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Chemistry

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Also known as:
Molecular Formula
C10H12N4O3
Molecular Weight
236.23  g/mol
InChI Key
BXZVVICBKDXVGW-NKWVEPMBSA-N

Didanosine
1 2D Structure

Didanosine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
9-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
2.1.2 InChI
InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1
2.1.3 InChI Key
BXZVVICBKDXVGW-NKWVEPMBSA-N
2.1.4 Canonical SMILES
C1CC(OC1CO)N2C=NC3=C2NC=NC3=O
2.1.5 Isomeric SMILES
C1C[C@@H](O[C@@H]1CO)N2C=NC3=C2NC=NC3=O
2.2 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 236.23 g/mol
Molecular Formula C10H12N4O3
XLogP3-1.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass236.09094026 g/mol
Monoisotopic Mass236.09094026 g/mol
Topological Polar Surface Area88.7 A^2
Heavy Atom Count17
Formal Charge0
Complexity348
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameDidanosine
Drug LabelDidanosine delayed-release capsules are an enteric-coated formulation of didanosine, (ddl), a synthetic purine nucleoside analogue active against the Human Immunodeficiency Virus (HIV). Didanosine delayed-release capsules, containing enteric-coated p...
Active IngredientDidanosine
Dosage FormCapsule, delayed rel pellets; Tablet, for suspension; For solution
RouteOral
Strength200mg; 250mg; 100mg; 125mg; 150mg; 10mg/ml; 400mg
Market StatusPrescription
CompanyMylan Pharms; Aurobindo; Aurobindo Pharma; Barr

2 of 6  
Drug NameVidex
PubMed HealthDidanosine (By mouth)
Drug ClassesAntiretroviral Agent
Drug LabelVIDEX is a brand name for didanosine, USP, a synthetic purine nucleoside analogue active against HIV-1. Didanosine is available as VIDEX, a Pediatric Powder for Oral Solution [see How Supplied/Storage and Handling (16)] and as VIDEX EC Delayed-Re...
Active IngredientDidanosine
Dosage FormFor solution
RouteOral
Strength10mg/ml
Market StatusPrescription
CompanyBristol Myers Squibb

3 of 6  
Drug NameVidex ec
PubMed HealthDidanosine (By mouth)
Drug ClassesAntiretroviral Agent
Drug LabelVIDEX EC is the brand name for an enteric-coated formulation of didanosine, USP, a synthetic purine nucleoside analogue active against HIV-1. VIDEX EC Delayed-Release Capsules, containing enteric-coated beadlets, are available for oral administrati...
Active IngredientDidanosine
Dosage FormCapsule, delayed rel pellets
RouteOral
Strength200mg; 250mg; 125mg; 400mg
Market StatusPrescription
CompanyBristol Myers Squibb

4 of 6  
Drug NameDidanosine
Drug LabelDidanosine delayed-release capsules are an enteric-coated formulation of didanosine, (ddl), a synthetic purine nucleoside analogue active against the Human Immunodeficiency Virus (HIV). Didanosine delayed-release capsules, containing enteric-coated p...
Active IngredientDidanosine
Dosage FormCapsule, delayed rel pellets; Tablet, for suspension; For solution
RouteOral
Strength200mg; 250mg; 100mg; 125mg; 150mg; 10mg/ml; 400mg
Market StatusPrescription
CompanyMylan Pharms; Aurobindo; Aurobindo Pharma; Barr

5 of 6  
Drug NameVidex
PubMed HealthDidanosine (By mouth)
Drug ClassesAntiretroviral Agent
Drug LabelVIDEX is a brand name for didanosine, USP, a synthetic purine nucleoside analogue active against HIV-1. Didanosine is available as VIDEX, a Pediatric Powder for Oral Solution [see How Supplied/Storage and Handling (16)] and as VIDEX EC Delayed-Re...
Active IngredientDidanosine
Dosage FormFor solution
RouteOral
Strength10mg/ml
Market StatusPrescription
CompanyBristol Myers Squibb

6 of 6  
Drug NameVidex ec
PubMed HealthDidanosine (By mouth)
Drug ClassesAntiretroviral Agent
Drug LabelVIDEX EC is the brand name for an enteric-coated formulation of didanosine, USP, a synthetic purine nucleoside analogue active against HIV-1. VIDEX EC Delayed-Release Capsules, containing enteric-coated beadlets, are available for oral administrati...
Active IngredientDidanosine
Dosage FormCapsule, delayed rel pellets
RouteOral
Strength200mg; 250mg; 125mg; 400mg
Market StatusPrescription
CompanyBristol Myers Squibb

DRUG PRODUCT COMPOSITIONS

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DOSAGE - FOR SOLUTION;ORAL - 10MG/ML

USFDA APPLICATION NUMBER - 20156

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DOSAGE - CAPSULE, DELAYED REL PELLETS;ORAL - ...DOSAGE - CAPSULE, DELAYED REL PELLETS;ORAL - 125MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 21183

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DOSAGE - CAPSULE, DELAYED REL PELLETS;ORAL - ...DOSAGE - CAPSULE, DELAYED REL PELLETS;ORAL - 200MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 21183

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DOSAGE - CAPSULE, DELAYED REL PELLETS;ORAL - ...DOSAGE - CAPSULE, DELAYED REL PELLETS;ORAL - 250MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 21183

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DOSAGE - CAPSULE, DELAYED REL PELLETS;ORAL - ...DOSAGE - CAPSULE, DELAYED REL PELLETS;ORAL - 400MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 21183

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