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Chemistry

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Also known as: 35898-87-4, Dilazep [inn], F8klc2bd5z, Chembl126075, 3,3'-(1,4-diazepan-1,4-diyl)dipropyl bis(3,4,5-trimethoxybenzoat), Dilazep (inn)
Molecular Formula
C31H44N2O10
Molecular Weight
604.7  g/mol
InChI Key
QVZCXCJXTMIDME-UHFFFAOYSA-N
FDA UNII
F8KLC2BD5Z

Dilazepam
Coronary vasodilator with some antiarrhythmic activity.
1 2D Structure

Dilazepam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-[4-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]-1,4-diazepan-1-yl]propyl 3,4,5-trimethoxybenzoate
2.1.2 InChI
InChI=1S/C31H44N2O10/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4/h18-21H,7-17H2,1-6H3
2.1.3 InChI Key
QVZCXCJXTMIDME-UHFFFAOYSA-N
2.1.4 Canonical SMILES
COC1=CC(=CC(=C1OC)OC)C(=O)OCCCN2CCCN(CC2)CCCOC(=O)C3=CC(=C(C(=C3)OC)OC)OC
2.2 Other Identifiers
2.2.1 UNII
F8KLC2BD5Z
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Asta C 4898

2. Biopropazepan Trimethoxybenzoate

3. C 4898, Asta

4. Cormelian

5. Trimethoxybenzoate, Biopropazepan

2.3.2 Depositor-Supplied Synonyms

1. 35898-87-4

2. Dilazep [inn]

3. F8klc2bd5z

4. Chembl126075

5. 3,3'-(1,4-diazepan-1,4-diyl)dipropyl Bis(3,4,5-trimethoxybenzoat)

6. Dilazep (inn)

7. Ncgc00016747-03

8. (1,4-diazepane-1,4-diyl)di(propane-3,1-diyl) Bis(3,4,5-trimethoxybenzoate)

9. Dsstox_cid_25425

10. Dsstox_rid_80871

11. Tetrahydro-1h-1,4-diazepine-1,4(5h)-dipropanol 3,4,5-trimethoxybenzoate (diester)

12. Dsstox_gsid_45425

13. Dilazepam

14. Dilazepum

15. 3-[4-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]-1,4-diazepan-1-yl]propyl 3,4,5-trimethoxybenzoate

16. Dilazepum [inn-latin]

17. Dilazepam [inn-spanish]

18. Benzoic Acid, 3,4,5-trimethoxy-,(tetrahydro-1h-1,4-diazepine-1,4(5h)-diyl)di-3,1-propanediyl Ester

19. Cas-35898-87-4

20. Unii-f8klc2bd5z

21. Benzoic Acid, 3,4,5-trimethoxy-, (tetrahydro-1h-1,4-diazepine-1,4(5h)-diyl)di-3,1-propanediyl Ester

22. Ki 2119

23. Tocris-0481

24. Dilazep [mi]

25. 20153-98-4

26. Prestwick0_000236

27. Prestwick1_000236

28. Prestwick2_000236

29. Prestwick3_000236

30. Dilazep [who-dd]

31. Lopac0_000369

32. Schembl48830

33. Bspbio_000311

34. Spbio_002232

35. Bpbio1_000343

36. Gtpl4717

37. Dtxsid9045425

38. Chebi:92842

39. Glxc-25687

40. Hms2090a11

41. 1,4-bis(3,4,5-trimethoxybenzyloxy)propyl)perhydro-1,4-diazepin

42. Tox21_110588

43. Bdbm50017691

44. Zinc22454221

45. 3,3'-(1,4-diazepan-1,4-diyl)dipropyl Bis(3,4,5-trimethoxybenzoat) [iupac]

46. Tox21_110588_1

47. Db13715

48. Ncgc00016747-01

49. Ncgc00016747-02

50. Ncgc00016747-04

51. Ncgc00016747-05

52. Ncgc00016747-07

53. Ncgc00024610-01

54. Ncgc00024610-02

55. 3-{4-[3-(3,4,5-trimethoxybenzoyloxy)propyl]-1,4-diazepan-1-yl}propyl 3,4,5-trimethoxybenzoate

56. Cas-20153-98-4

57. D07843

58. Q5276700

59. Sr-01000075817-3

60. Brd-k48722258-003-04-5

61. Brd-k48722258-300-03-7

62. Brd-k48722258-300-05-2

63. Brd-k48722258-300-07-8

64. (1,4-diazepane-1,4-diyl)bis(propane-3,1-diyl) Bis(3,4,5-trimethoxybenzoate)

65. 3,3'-(1,4-diazepane-1,4-diyl)bis(propane-3,1-diyl) Bis(3,4,5-trimethoxybenzoate)

66. 3,4,5-trimethoxybenzoic Acid 3-[4-[3-[oxo-(3,4,5-trimethoxyphenyl)methoxy]propyl]-1,4-diazepan-1-yl]propyl Ester

67. 8dz

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 604.7 g/mol
Molecular Formula C31H44N2O10
XLogP34.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count12
Rotatable Bond Count18
Exact Mass604.29959560 g/mol
Monoisotopic Mass604.29959560 g/mol
Topological Polar Surface Area115 Ų
Heavy Atom Count43
Formal Charge0
Complexity727
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Vasodilator Agents

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)


4.2 ATC Code

C - Cardiovascular system

C01 - Cardiac therapy

C01D - Vasodilators used in cardiac diseases

C01DX - Other vasodilators used in cardiac diseases

C01DX10 - Dilazep


ABOUT THIS PAGE

Dilazepam Manufacturers

A Dilazepam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Dilazepam, including repackagers and relabelers. The FDA regulates Dilazepam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Dilazepam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Dilazepam Suppliers

A Dilazepam supplier is an individual or a company that provides Dilazepam active pharmaceutical ingredient (API) or Dilazepam finished formulations upon request. The Dilazepam suppliers may include Dilazepam API manufacturers, exporters, distributors and traders.

Dilazepam GMP

Dilazepam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Dilazepam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Dilazepam GMP manufacturer or Dilazepam GMP API supplier for your needs.

Dilazepam CoA

A Dilazepam CoA (Certificate of Analysis) is a formal document that attests to Dilazepam's compliance with Dilazepam specifications and serves as a tool for batch-level quality control.

Dilazepam CoA mostly includes findings from lab analyses of a specific batch. For each Dilazepam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Dilazepam may be tested according to a variety of international standards, such as European Pharmacopoeia (Dilazepam EP), Dilazepam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Dilazepam USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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