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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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MARKET PLACE

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API

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FDF

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Canada

Canada

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Australia

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DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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GLOBAL SALES INFORMATION

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Chemistry

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Also known as: Dimeflin, Dimelfin, Malivan, Reanimil, 1165-48-6, Remeflin
Molecular Formula
C20H21NO3
Molecular Weight
323.4  g/mol
InChI Key
ZXFQRFXLFWWKLX-UHFFFAOYSA-N
FDA UNII
9WII5M0DU3

Dimefline
1 2D Structure

Dimefline

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenylchromen-4-one
2.1.2 InChI
InChI=1S/C20H21NO3/c1-13-18(22)15-10-11-17(23-4)16(12-21(2)3)20(15)24-19(13)14-8-6-5-7-9-14/h5-11H,12H2,1-4H3
2.1.3 InChI Key
ZXFQRFXLFWWKLX-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(OC2=C(C1=O)C=CC(=C2CN(C)C)OC)C3=CC=CC=C3
2.2 Other Identifiers
2.2.1 UNII
9WII5M0DU3
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Dimefline Hydrochloride

2.3.2 Depositor-Supplied Synonyms

1. Dimeflin

2. Dimelfin

3. Malivan

4. Reanimil

5. 1165-48-6

6. Remeflin

7. Nsc 169869

8. Remeflin (van)

9. Nsc169869

10. Nsc-169869

11. 8-(dimethylaminomethyl)-7-methoxy-3-methylflavone

12. 9wii5m0du3

13. 8-((dimethylamino)methyl)-7-methoxy-3-methylflavone

14. 4h-1-benzopyran-4-one, 8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenyl-

15. N-(7-methoxy-3-methyl-4-oxo-2-phenyl-4h-chromen-8-yl)methyl-n,n-dimethylamine

16. Dimefline (inn)

17. 4h-1-benzopyran-4-one, 8-((dimethylamino)methyl)-7-methoxy-3-methyl-2-phenyl-

18. Dimefline [inn]

19. Dw 62

20. 8-[(dimethylamino)methyl]-7-methoxy-3-methylflavone

21. Flavone, 8-[(dimethylamino)methyl]-7-methoxy-3-methyl-

22. Dimeflinum

23. Dimeflina

24. Dimefline [inn:ban]

25. Dimeflinum [inn-latin]

26. Dimeflina [inn-spanish]

27. 8-((dimethylamino)methyl)-7-methoxy-3-methyl-2-phenyl-4h-chromen-4-one

28. Nsc114650

29. Hsdb 2110

30. Ncgc00181097-01

31. Einecs 214-616-4

32. Unii-9wii5m0du3

33. Flavone, 8-((dimethylamino)methyl)-7-methoxy-3-methyl-

34. Brn 1395114

35. Flavone, 8-(dimethylaminomethyl)-7-methoxy-3-methyl-

36. 8-dimethylaminomethyl-7-methoxy-3-methyl-2-phenylchromone

37. 8-((dimethylamino)methyl)-7-methoxy-3-methyl-2-phenylflavone

38. Dimefline [mi]

39. Dimefline [hsdb]

40. Dw 62 (salt/mix)

41. 8-((dimethylamino)methyl)-7-methoxy-3-methyl-2-phenyl-4h-1-benzopyran-4-one

42. Dimefline [who-dd]

43. 3-methyl-7-methoxy-8-dimethylamino-methylflavone

44. Zinc223

45. 5-18-12-00083 (beilstein Handbook Reference)

46. Schembl668130

47. Chembl519364

48. Dtxsid0048268

49. Rec 7/0267 (salt/mix)

50. Chebi:135374

51. Db13482

52. Nci60_000333

53. Nci60_001369

54. D07847

55. Wln: T66 Bo Evj Cr& D1 Io1 J1n1&1

56. Q5277233

57. 3-methyl-7-methoxy-8-[(dimethylamino)methyl]flavone

58. 8-((dimethylamino)methyl)-7-methoxy-3-methyl-2-phenylchromone

59. 8-(dimethylaminomethyl)-7-methoxy-3-methyl-2-phenyl-chromen-4-one

60. 8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenylchromen-4-one

61. 8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenyl-4h-chromen-4-one #

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 323.4 g/mol
Molecular Formula C20H21NO3
XLogP33.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass323.15214353 g/mol
Monoisotopic Mass323.15214353 g/mol
Topological Polar Surface Area38.8 Ų
Heavy Atom Count24
Formal Charge0
Complexity493
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

R - Respiratory system

R07 - Other respiratory system products

R07A - Other respiratory system products

R07AB - Respiratory stimulants

R07AB08 - Dimefline


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ABOUT THIS PAGE

Dimefline Manufacturers

A Dimefline manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Dimefline, including repackagers and relabelers. The FDA regulates Dimefline manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Dimefline API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Dimefline manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Dimefline Suppliers

A Dimefline supplier is an individual or a company that provides Dimefline active pharmaceutical ingredient (API) or Dimefline finished formulations upon request. The Dimefline suppliers may include Dimefline API manufacturers, exporters, distributors and traders.

click here to find a list of Dimefline suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Dimefline GMP

Dimefline Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Dimefline GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Dimefline GMP manufacturer or Dimefline GMP API supplier for your needs.

Dimefline CoA

A Dimefline CoA (Certificate of Analysis) is a formal document that attests to Dimefline's compliance with Dimefline specifications and serves as a tool for batch-level quality control.

Dimefline CoA mostly includes findings from lab analyses of a specific batch. For each Dimefline CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Dimefline may be tested according to a variety of international standards, such as European Pharmacopoeia (Dimefline EP), Dimefline JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Dimefline USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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