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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

9 API Suppliers, 4 USDMF, 2 CEP/COS, 2 JDMF, 1 EU WC, 3 NDC API, 3 Listed Suppliers, $ API Reference Price

9 API Suppliers
4 USDMF
2 CEP/COS
2 JDMF
1 EU WC
3 NDC API
3 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

28 FDF Dossiers, 2 Europe, 14 Canada, 7 South Africa, 5 Listed Dossiers

28 FDF Dossiers
2 Europe
14 Canada
7 South Africa
5 Listed Dossiers

RELATED EXCIPIENT COMPANIES

11 Evonik, 18 Rochem International Inc, 27 SPI Pharma, 2 Seqens, 29 DKSH, 2 Pharm-RX Chemical, 12 Faran Shimi Pharmaceutical, 6 Boai NKY Pharmaceuticals Ltd, 15 Gangwal Healthcare, 2 Kewpie Corporation, 29 Nanjing Well Pharmaceutical, 7 Pfanstiehl, 4 ACG Worldwide, 30 Actylis, 4 Aeon Procare, 2 Alcedo Pharmachem, 8 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 53 BASF, 8 Beneo, 2 Bioplus Life Sciences, 2 BioSpectra, 2 Clariant, 22 Corel Pharma Chem, 4 DFE Pharma, 6 Finar, 21 Gangwal Chemicals, 3 Hayashibara, 1 Huzhou Sunflower Pharmaceutical, 8 Ideal Cures Pvt Ltd, 5 Ingredion Pharma Solutions, 21 Kerry, 4 Kima Chemical, 6 Lonza Capsugel, 10 Lubrizol Life Science Health, 24 Microlex e.U, 2 Nanjing Bold Chemical, 2 Nippon Fine Chemical, 2 Nomisma Healthcare, 4 Novo Excipients, 3 Pharmatrans-Sanaq, 14 Pluviaendo, 4 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 2 Qualicaps, 49 Roquette, 31 Seppic, 3 Shandong Focus Biotechnology Co., Ltd, 1 Shanghai Hegeng Industrial Co. Ltd, 7 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 3 Shijiazhuang Huaxu Pharmaceutical, 11 Sigachi Industries, 3 The Dow Chemical Company, 1 TopChem Pharmaceuticals, 1 Ulanqab Kema New Material, 2 Valens Pharmachem, 4 Vasa Pharmachem, 3 Zhejiang Huakang Pharmaceutical

relatedExcipients
11 Evonik
18 Rochem International Inc
27 SPI Pharma
2 Seqens
29 DKSH
2 Pharm-RX Chemical
12 Faran Shimi Pharmaceutical
6 Boai NKY Pharmaceuticals Ltd
15 Gangwal Healthcare
2 Kewpie Corporation
29 Nanjing Well Pharmaceutical
7 Pfanstiehl
4 ACG Worldwide
30 Actylis
4 Aeon Procare
2 Alcedo Pharmachem
8 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
53 BASF
8 Beneo
2 Bioplus Life Sciences
2 BioSpectra
2 Clariant
22 Corel Pharma Chem
4 DFE Pharma
6 Finar
21 Gangwal Chemicals
3 Hayashibara
1 Huzhou Sunflower Pharmaceutical
8 Ideal Cures Pvt Ltd
5 Ingredion Pharma Solutions
21 Kerry
4 Kima Chemical
6 Lonza Capsugel
10 Lubrizol Life Science Health
24 Microlex e.U
2 Nanjing Bold Chemical
2 Nippon Fine Chemical
2 Nomisma Healthcare
4 Novo Excipients
3 Pharmatrans-Sanaq
14 Pluviaendo
4 Prachin Chemical
1 Qianhao Chemical (Hebei) Co., Ltd
2 Qualicaps
49 Roquette
31 Seppic
3 Shandong Focus Biotechnology Co., Ltd
1 Shanghai Hegeng Industrial Co. Ltd
7 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
1 Shanghai Welltone Material Technology Co., Ltd
3 Shijiazhuang Huaxu Pharmaceutical
11 Sigachi Industries
3 The Dow Chemical Company
1 TopChem Pharmaceuticals
1 Ulanqab Kema New Material
2 Valens Pharmachem
4 Vasa Pharmachem
3 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

123 Topical, 110 Fillers, Diluents & Binders, 83 Thickeners and Stabilizers, 76 Solubilizers, 67 Coating Systems & Additives, 56 Taste Masking, 54 Parenteral, 50 Direct Compression, 48 Controlled & Modified Release, 40 Emulsifying Agents, 38 Granulation, 37 Film Formers & Plasticizers, 36 Lubricants & Glidants, 34 Disintegrants & Superdisintegrants, 29 Chewable & Orodispersible Aids, 27 Surfactant & Foaming Agents, 25 Co-Processed Excipients, 15 Rheology Modifiers, 12 API Stability Enhancers, 9 Empty Capsules, 5 Coloring Agents, 4 Vegetarian Capsules, 1 Soft Gelatin

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 3 NEWS #PharmaBuzz

media
1 DATA COMPILATION #PharmaFlow
3 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 Finished Drug Prices

globalSalesInformation
1 Finished Drug Prices

MARKET PLACE

10 APIs, 1 FDF Dossiers, 10 EXCIPIENTS

marketPlace
10 APIs
1 FDF Dossiers
10 EXCIPIENTS

REF. STANDARDS & IMPURITIES

2 EDQM

otherSolutions
2 EDQM

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 11

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

564 RELATED EXCIPIENT COMPANIES

979EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 107-51-7, Trisiloxane, octamethyl-, Poly(dimethylsiloxane), 1,1,1,3,3,5,5,5-octamethyltrisiloxane, Dimeticone, Dimethyl-bis(trimethylsilyloxy)silane

Molecular Formula

C₈H₂₄O₂Si₃

Molecular Weight

236.53 g/mol

InChI Key

CXQXSVUQTKDNFP-UHFFFAOYSA-N

FDA UNII

9G1ZW13R0G

1 2D Structure

Dimethicone

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

dimethyl-bis(trimethylsilyloxy)silane

2.1.2 InChI

InChI=1S/C8H24O2Si3/c1-11(2,3)9-13(7,8)10-12(4,5)6/h1-8H3

2.1.3 InChI Key

CXQXSVUQTKDNFP-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C

2.2 Other Identifiers

2.2.1 UNII

9G1ZW13R0G

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Baysilon

2. Macroplastique

3. Poly(dimethylsiloxane)

4. Polydimethylsiloxane

5. Rtv S-5392

6. Silastic

7. Siliconique

8. Silikon 1000

9. Simpa

2.3.2 Depositor-Supplied Synonyms

1. 107-51-7

2. Trisiloxane, Octamethyl-

3. Poly(dimethylsiloxane)

4. 1,1,1,3,3,5,5,5-octamethyltrisiloxane

5. Dimeticone

6. Dimethyl-bis(trimethylsilyloxy)silane

7. Dimethicone 350

8. 63148-62-9

9. Pentamethyl(trimethylsilyloxy)disiloxane

10. Dimethylbis(trimethylsiloxy)silane

11. 9g1zw13r0g

12. Chebi:9147

13. Trisiloxane, 1,1,1,3,3,5,5,5-octamethyl-

14. Dimethylbis(trimethylsilyloxy)silane

15. Dimethicones

16. Poly(dimethylsiloxane), Hydroxy Terminated

17. Mfcd00084411

18. Mfcd00134211

19. Mfcd00148360

20. Ccris 3198

21. Poly(dimethylsiloxane), Trimethylsiloxy Terminated

22. Einecs 203-497-4

23. Dimeticonum

24. Unii-9g1zw13r0g

25. Dimeticona

26. Frd 20

27. Ctamethyltrisiloxane

28. Mfcd00008264

29. Pentamethyl(trimethylsiloxy)disiloxane

30. Octamethyl-trisiloxane

31. Pdms

32. Dimethicone Macromolecule

33. Volasil Dm-1

34. Silicon Oil For Oil Bath

35. Trisiloxane [inci]

36. Dm-fluid 1.0cs

37. Ec 203-497-4

38. Octamethyltrisiloxane, 98%

39. Dsstox_cid_20710

40. Dsstox_rid_79558

41. Dsstox_gsid_40710

42. Os 20 (siloxane)

43. Schembl23459

44. Siliconoil Pharma 100 Cst.

45. Dimethyl Polysiloxane, Bis(trimethylsilyl)-terminated

46. Dow Corning High-vacuum Grease

47. Chembl2142985

48. Dtxsid9040710

49. Chebi:31498

50. Cxqxsvuqtkdnfp-uhfffaoysa-

51. Kf 96a1

52. Octamethyltrisiloxane [mi]

53. Dimethylbis(trimethylsiloxy)siliane

54. Polydimethylsiloxane, 1000 Cst.

55. Alpha-(trimethylsilyl)-omega-methylpoly(oxy(dimethylsilylene))

56. [(ch3)3sio]2si(ch3)2

57. Tox21_301002

58. Co9816

59. Mfcd00165850

60. Silane, Dimethylbis(trimethylsiloxy)-

61. Akos015840180

62. Zinc169747808

63. Antifoam Compound For Anhydrous Systems

64. Fs-4459

65. Ncgc00164100-01

66. Ncgc00164100-02

67. Ncgc00254904-01

68. Cas-107-51-7

69. Db-040764

70. Ft-0631598

71. Ft-0696355

72. O0257

73. O9816

74. C07261

75. D91850

76. S12475

77. A801717

78. Xiameter(r) Pmx-200 Silicone Fluid 1 Cst

79. J-001906

80. Poly(dimethylsiloxane), Viscosity 1.0 Cst (25 C)

81. Q2013799

82. Xiameter(r) Pmx-200 Silicone Fluid 20 Cs

83. 2,2,4,4,6,6-hexamethyl-3,5-dioxa-2,4,6-trisilaheptane

84. Polydimethylsiloxane, 20,000 Cst. Trimethoxysilyl Terminated

85. Polydimethylsiloxane, Extreme Low Volatility, Viscosity 1000 Cst.

86. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 20% Active, Viscosity 1500cst

87. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 30% Active, Viscosity 1500cst

88. Polydimethylsiloxane, Trimethylsiloxy Terminated, Reduced Volatility, Viscosity 20 Cst.

89. 28349-86-2

90. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 10% Active, Viscosity 1000-2000cst

91. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 10% Active, Viscosity 800-2000cst

92. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 20% Active, Viscosity 1000-2000cst

93. Intermediate Viscosity Polydimethylsiloxane Antifoam Emulsion, 30% Active, Viscosity 1000-2000cst

94. Polydimethylsiloxane, Trimethylsiloxy Terminated, Extreme Low Volatility, Viscosity 12.500 Cst.

2.4 Create Date

2005-03-27

3 Chemical and Physical Properties

Molecular Formula	C₈H₂₄O₂Si₃
Molecular Weight	236.53 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Exact Mass	236.10840961 g/mol
Monoisotopic Mass	236.10840961 g/mol
Topological Polar Surface Area	18.5 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	149
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 FDA Pharmacological Classification

4.1.1 Pharmacological Classes

Skin Barrier Activity [PE]

4.2 ATC Code

P - Antiparasitic products, insecticides and repellents

P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents

P03A - Ectoparasiticides, incl. scabicides

P03AX - Other ectoparasiticides, incl. scabicides

P03AX05 - Dimeticone

API SUPPLIERS

01

Jai Radhe Sales

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

Jai Radhe Sales is your partner for all your sourcing needs.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

02

Pharm-RX Chemical

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

Corporate PDF

03

RioCare India Pvt. Ltd.

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

04

RioCare India Pvt. Ltd.

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

05

The Dow Chemical Company

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

06

The Dow Chemical Company

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

07

Sichuan Renan Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

08

Dupont

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

09

Dupont

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

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USDMF

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CEP/COS

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JDMF

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EU WC

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NDC API

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Listed Suppliers

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API Reference Price

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MAHARASHTRA.","supplier":"CRODA INTERNATIONAL PLC","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. K","customer":"CRODA INTERNATIONAL PLC","customerCountry":"INDIA","quantity":"72.00","actualQuantity":"72","unit":"KGS","unitRateFc":"47.4","totalValueFC":"3989.9","currency":"USD","unitRateINR":"4612.9","date":"21-Dec-2023","totalValueINR":"332130.88","totalValueInUsd":"3989.9","indian_port":"Bombay Air","hs_no":"29232090","bill_no":"9340238","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"777 SCUDDERS MILL ROAD, BLDG. 2 SUITE 200 PLAINSBORO, NJ 08536 New JERSEY, , UNITED STATES UNITED STATES","customerAddress":"PLOT NO 1\/1 PART TTC INDL AREA"}]