Find Diprenorphine manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 14357-78-9, Diprenorfin, Revivon, Dea no. 9058, 1f0l5n25zz, Chebi:4650
Molecular Formula
C26H35NO4
Molecular Weight
425.6  g/mol
InChI Key
OIJXLIIMXHRJJH-KNLIIKEYSA-N
FDA UNII
1F0L5N25ZZ

Diprenorphine
A narcotic antagonist similar in action to NALOXONE. It is used to remobilize animals after ETORPHINE neuroleptanalgesia and is considered a specific antagonist to etorphine.
1 2D Structure

Diprenorphine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-(2-hydroxypropan-2-yl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
2.1.2 InChI
InChI=1S/C26H35NO4/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25/h6-7,15,18-19,22,28-29H,4-5,8-14H2,1-3H3/t18-,19-,22-,24-,25+,26-/m1/s1
2.1.3 InChI Key
OIJXLIIMXHRJJH-KNLIIKEYSA-N
2.1.4 Canonical SMILES
CC(C)(C1CC23CCC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)O
2.1.5 Isomeric SMILES
CC(C)([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)O
2.2 Other Identifiers
2.2.1 UNII
1F0L5N25ZZ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Diprenorphine Hydrochloride

2. Hydrochloride, Diprenorphine

3. Revivon

2.3.2 Depositor-Supplied Synonyms

1. 14357-78-9

2. Diprenorfin

3. Revivon

4. Dea No. 9058

5. 1f0l5n25zz

6. Chebi:4650

7. Chembl281786

8. M. 5050

9. Diprenorphine (inn)

10. M50-50 Injection

11. M5050

12. Diprenorphine [inn:ban]

13. Diprenorphine [inn]

14. M-5050

15. Diprenorfina [inn-spanish]

16. (1s,2s,6r,14r,15r,16r)-5-(cyclopropylmethyl)-16-(2-hydroxypropan-2-yl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol

17. Diprenorfina

18. Diprenorphinum

19. 21-cyclopropyl-6,7,8,14-tetrahydro-7alpha-(1-hydroxy-1-methylethyl)-6,14-endo-ethanooripavine

20. Diprenorphinum [inn-latin]

21. Unii-1f0l5n25zz

22. (5?,7?)-17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-?,?-dimethyl-6,14-ethenomorphinan-7-methanol

23. Einecs 238-325-7

24. M 5050 Injection

25. Diprenorphine-hcl

26. Diprenorphine [mi]

27. M50-50

28. Schembl164910

29. Gtpl1617

30. Dtxsid00903941

31. Zinc4102215

32. Bdbm50001714

33. Akos024457358

34. Db01548

35. 6,14-ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-.alpha.,.alpha.-dimethyl-, (5.alpha.,7.alpha.)-

36. 6,14-ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha,alpha-dimethyl-, (5alpha,7alpha)-

37. Hy-107742

38. D07863

39. M 5050

40. Q424009

41. Epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha,alpha-dimethyl-, (5alpha,7alpha)-

42. (5alpha,7alpha)-17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha,alpha-dimethyl-6,14-ethenomorphinan-7-methanol

43. 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-?,?-dimethyl-6,14-ethenomorphinan-7-methanol

44. 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1s,2r,6s,14r,15r,16r)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-2-propanol

45. 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1s,2r,6s,14r,15r,16r)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-2-propanol(diprenorphine)

46. 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7(12),8,10-trien-16-yl]-2-propanol

47. 6,14-endo-ethanotetrahydrooripavine, 21-cyclopropyl-7a-(1-hydroxy-1-methylethyl)- (8ci) 1-n-cyclopropylmethyl-6,7,8,14-tetrahydro-6,14-endoethano-7-(2'-hydroxy-2'-propyl)nororipavine

48. 6,14-ethenomorphinan-3-ol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-18-(1-hydroxy-1-methylethyl)-6-methoxy-, (5alpha,6beta,14beta,18r)-

49. 6,14-ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha,alpha-dimethyl-, (5alpha,7alpha)- (9ci)

2.4 Create Date
2005-06-01
3 Chemical and Physical Properties
Molecular Weight 425.6 g/mol
Molecular Formula C26H35NO4
XLogP33.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass425.25660860 g/mol
Monoisotopic Mass425.25660860 g/mol
Topological Polar Surface Area62.2 Ų
Heavy Atom Count31
Formal Charge0
Complexity783
Isotope Atom Count0
Defined Atom Stereocenter Count6
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Diprenorphine is indicated to reverse the effects of powerful opioids including etorphine and carfentanil, often used for tranquilizing large animals. This drug is not approved for use in humans.


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Narcotic Antagonists

Agents inhibiting the effect of narcotics on the central nervous system. (See all compounds classified as Narcotic Antagonists.)


5.2 Mechanism of Action

Diprenorphine binds approximately equally to the three subtypes of opioid receptorsand antagonizes them.


ABOUT THIS PAGE

Diprenorphine Manufacturers

A Diprenorphine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Diprenorphine, including repackagers and relabelers. The FDA regulates Diprenorphine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Diprenorphine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Diprenorphine Suppliers

A Diprenorphine supplier is an individual or a company that provides Diprenorphine active pharmaceutical ingredient (API) or Diprenorphine finished formulations upon request. The Diprenorphine suppliers may include Diprenorphine API manufacturers, exporters, distributors and traders.

Diprenorphine GMP

Diprenorphine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Diprenorphine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Diprenorphine GMP manufacturer or Diprenorphine GMP API supplier for your needs.

Diprenorphine CoA

A Diprenorphine CoA (Certificate of Analysis) is a formal document that attests to Diprenorphine's compliance with Diprenorphine specifications and serves as a tool for batch-level quality control.

Diprenorphine CoA mostly includes findings from lab analyses of a specific batch. For each Diprenorphine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Diprenorphine may be tested according to a variety of international standards, such as European Pharmacopoeia (Diprenorphine EP), Diprenorphine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Diprenorphine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty