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Docosahexaenoic Acid

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ACTIVE PHARMA INGREDIENTS

11 API Suppliers, 4 USDMF, 7 Listed Suppliers, $ API Reference Price

11 API Suppliers
4 USDMF
7 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

5 Drugs in Development

5 Drugs in Development

FINISHED DOSAGE FORMULATIONS

23 FDF Dossiers, 23 Listed Dossiers

23 FDF Dossiers
23 Listed Dossiers

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1 Evonik
5 Rochem International Inc
18 SPI Pharma
2 Seqens
9 DKSH
1 Pharm-RX Chemical
7 Faran Shimi Pharmaceutical
1 Boai NKY Pharmaceuticals Ltd
13 Gangwal Healthcare
2 Kewpie Corporation
6 Nanjing Well Pharmaceutical
2 Pfanstiehl
4 ACG Worldwide
9 Actylis
1 Aeon Procare
7 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
25 BASF
1 Bioplus Life Sciences
11 Corel Pharma Chem
3 DFE Pharma
2 Finar
12 Gangwal Chemicals
7 Ideal Cures Pvt Ltd
4 Ingredion Pharma Solutions
21 Kerry
4 Kima Chemical
6 Lonza Capsugel
13 Microlex e.U
1 Nanjing Bold Chemical
2 Nomisma Healthcare
3 Novo Excipients
2 Pharmatrans-Sanaq
8 Pluviaendo
3 Prachin Chemical
1 Qianhao Chemical (Hebei) Co., Ltd
2 Qualicaps
30 Roquette
13 Seppic
6 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
2 Shijiazhuang Huaxu Pharmaceutical
10 Sigachi Industries
3 The Dow Chemical Company
1 Valens Pharmachem
3 Vasa Pharmachem
2 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

76 Fillers, Diluents & Binders, 56 Coating Systems & Additives, 37 Direct Compression, 34 Controlled & Modified Release, 30 Thickeners and Stabilizers, 28 Solubilizers, 26 Taste Masking, 24 Parenteral, 22 Film Formers & Plasticizers, 22 Disintegrants & Superdisintegrants, 22 Granulation, 20 Topical, 19 Co-Processed Excipients, 17 Chewable & Orodispersible Aids, 16 Lubricants & Glidants, 13 Emulsifying Agents, 9 Empty Capsules, 8 API Stability Enhancers, 5 Coloring Agents, 4 Vegetarian Capsules, 4 Rheology Modifiers, 2 Surfactant & Foaming Agents, 1 Soft Gelatin

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5 APIs

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5 APIs

REF. STANDARDS & IMPURITIES

1 EDQM , 1 USP , 2 Others

otherSolutions
1 EDQM
1 USP
2 Others

ANALYTICAL

1 Analytical Methods

otherMethods
1 Analytical Methods

Symbiotec DHA

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 64

MARKET PLACE

API

FDF

0INTERMEDIATES

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FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

5DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

289 RELATED EXCIPIENT COMPANIES

495EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Doconexent, Cervonic acid, 6217-54-5, Cis-4,7,10,13,16,19-docosahexaenoic acid, Docosahexaenoate, (4z,7z,10z,13z,16z,19z)-docosa-4,7,10,13,16,19-hexaenoic acid

Molecular Formula

C₂₂H₃₂O₂

Molecular Weight

328.5 g/mol

InChI Key

MBMBGCFOFBJSGT-KUBAVDMBSA-N

FDA UNII

ZAD9OKH9JC

C22-unsaturated fatty acids found predominantly in FISH OILS.

1 2D Structure

DHA

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid

2.1.2 InChI

InChI=1S/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-

2.1.3 InChI Key

MBMBGCFOFBJSGT-KUBAVDMBSA-N

2.1.4 Canonical SMILES

CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)O

2.1.5 Isomeric SMILES

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O

2.2 Other Identifiers

2.2.1 UNII

ZAD9OKH9JC

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Acid, Docosahexaenoic

2. Acids, Docosahexaenoic

3. Acids, Docosahexenoic

4. Docosahexaenoate

5. Docosahexaenoic Acid (all-z Isomer)

6. Docosahexaenoic Acid Dimer (all-z Isomer)

7. Docosahexaenoic Acid, 3,6,9,12,15,18-isomer

8. Docosahexaenoic Acid, 4,7,10,13,16,19-(all-z-isomer)

9. Docosahexaenoic Acid, 4,7,10,13,16,19-(all-z-isomer), Cerium Salt

10. Docosahexaenoic Acid, 4,7,10,13,16,19-(all-z-isomer), Cesium Salt

11. Docosahexaenoic Acid, 4,7,10,13,16,19-(all-z-isomer), Potassium Salt

12. Docosahexaenoic Acid, 4,7,10,13,16,19-(z,z,z,z,z,e-isomer)

13. Docosahexaenoic Acid, 4,7,10,13,16,19-isomer

14. Docosahexaenoic Acid, 4,7,10,13,16,19-isomer, Sodium Salt

15. Docosahexaenoic Acid, Sodium Salt

16. Docosahexaenoic Acids

17. Docosahexenoic Acids

2.3.2 Depositor-Supplied Synonyms

1. Doconexent

2. Cervonic Acid

3. 6217-54-5

4. Cis-4,7,10,13,16,19-docosahexaenoic Acid

5. Docosahexaenoate

6. (4z,7z,10z,13z,16z,19z)-docosa-4,7,10,13,16,19-hexaenoic Acid

7. All-cis-dha

8. Doconexento

9. Doconexentum

10. Doxonexent

11. Aquagrow Advantage

12. All-z-docosahexaenoic Acid

13. Doconexent [inn]

14. Martek Dha Hm

15. Ropufa 60

16. All-cis-4,7,10,13,16,19-docosahexaenoic Acid

17. (4z,7z,10z,13z,16z,19z)-docosahexaenoic Acid

18. Docosaheaenoic-acid

19. Docosahexaenoic Acid (all-z)

20. Ccris 7670

21. All-cis-docosa-4,7,10,13,16,19-hexaenoic Acid

22. Zad9okh9jc

23. Docosahexanoic Acid

24. (all-z)-4,7,10,13,16,19-docosahexaenoic Acid

25. Docosa-4,7,10,13,16,19-hexaenoic Acid

26. (4z,7z,10z,13z,16z,19z)-4,7,10,13,16,19-docosahexaenoic Acid

27. Chembl367149

28. Docosahexaenoic Acid(dha)

29. Chebi:28125

30. Delta4,7,10,13,16,19-docosahexaenoic Acid

31. 4-cis,7-cis,10-cis,13-cis,16-cis,19-cis-docosahexaenoic Acid

32. 4z,7z,10z,13z,16z,19z-docosahexaenoic Acid

33. Docosahexaenoic Acid (c22:6 N3)

34. Omega-3 Marine Triglycerides

35. Mfcd00065722

36. 4,7,10,13,16,19-docosahexaenoic Acid, (all-z)-

37. Fa 22:6

38. Efalex

39. Ncgc00161345-04

40. C22:6 (n-3)

41. Docosahexaenoic Acid (22:6 N-3)

42. 22:6 N-3

43. 22:6(n-3)

44. Cis-4,7,10,13,16,19-docosahexanoic Acid

45. 4,7,10,13,16,19-docosahexaenoic Acid

46. C22:6n-3,6,9,12,15,18

47. Monolife 50

48. Marinol D 50tg

49. Sr-05000002130

50. Unii-zad9okh9jc

51. Doconexentum [inn-latin]

52. Doconexento [inn-spanish]

53. Dha-[21,21,22,22,22-d5]

54. Cervonate

55. Dtxsid5040465

56. 1fdq

57. Algal Dha

58. Docohexanenoic Acid

59. Docosahexanenoic Acid

60. Omega 3 Fatty Acid

61. All-z-docosahexaenoate

62. Spectrum5_002062

63. Docosahexaenoic Acid (6ci)

64. Dsstox_cid_20465

65. Dsstox_rid_79498

66. Dsstox_gsid_40465

67. Schembl19577

68. Bspbio_001298

69. Docoshexaenoic Acid (powder)

70. Mls004773950

71. Bml3-b02

72. Gtpl1051

73. Retriacyl (proposed Trade Name)

74. Bcbcmap01_000145

75. Docosahexaenoic Acid [mi]

76. Hms1361a20

77. Hms1791a20

78. Hms1989a20

79. Hms3402a20

80. Hms3649j15

81. Docosahexaenoic Acid [inci]

82. Hy-b2167

83. Zinc4474564

84. Docosahexaenoic Acid [vandf]

85. Tox21_111992

86. Bdbm50210259

87. Docosahexaenoic Acid [mart.]

88. Lmfa01030185

89. Docosahexaenoic Acid [usp-rs]

90. Docosahexaenoic Acid [who-dd]

91. Akos015962159

92. Ac-1010

93. Ccg-207958

94. Ccg-208135

95. Cs-6261

96. Db03756

97. Kl-0761

98. Idi1_033768

99. 4,7,10,13,16,19-docosahexaenoate

100. Ncgc00161345-01

101. Ncgc00161345-02

102. Ncgc00161345-03

103. Ncgc00161345-05

104. Ncgc00161345-07

105. All Cis- Docosahexaenoic Acid (cis-dha)

106. Smr001881493

107. Cas-6217-54-5

108. Cis-4,7,10,13,16,19-docosahexanoate

109. D2226

110. S6454

111. C06429

112. H10987

113. Ab01563379_01

114. Docosahexaenoic Acid (dha) (c22:6 N3)

115. Docosahexaenoic Acid-rich Single Cell Oil

116. 217d545

117. Q423345

118. Sr-05000002130-1

119. Sr-05000002130-4

120. Brd-k39965020-001-02-6

121. 4,7,10,13,16,19-docosahexaenoic Acid, (all Cis)-

122. A320050000

123. Cis-4,7,10,13,16,19-docosahexaenoic Acid, >=98%

124. Fa(22:6(4z,7z,10z,13z,16z,19z))

125. Z,z,z,z,z,z-docosa-4,7,10,13,16,19-hexaenoic Acid

126. (all-z)-4,7,10,13,16,19-docosahexaenoic Acid, Dha

127. 800e8e72-bbf4-46f7-a60b-b8f2b54669c7

128. C22h32o2 (cis-4,7,10,13,16,19-docosahexaenoic Acid)

129. 4,7,10,13,16,19-docosahexaenoic Acid, (all-z)- (8ci)

130. Cis-4,7,10,13,16,19-docosahexaenoic Acid, Analytical Standard

131. Docosa-4z,7z,10z,13z,16z,19z-hexaenoic Acid (22:6, N-3)

132. (4z,7z,10z,13z,16z, 19z)-docosa-4,7,10,13,16,19-hexaenoic Acid

133. (4z,7z,10z,13z,16z,19z)-docosa-4, 7,10,13,16,19-hexaenoic Acid

134. (4z,7z,10z,13z,16z,19z)-docosa-4,7,10,13,16,19- Hexaenoic Acid

135. Cis-4,7,13,16,19-docosahexaenoic Acid (stabilized With Vitamine E)

136. 4,7,10,13,16,19-docosahexaenoic Acid, (4z,7z,10z,13z,16z,19z)- (9ci)

137. Docosahexaenoic Acid (dha) (c22:6) (constituent Of Krill Oil) [dsc]

138. 1024594-51-1

139. Cis-4,7,10,13,16,19-docosahexaenoic Acid, 500 Mug/ml In Ethanol, Certified Reference Material

2.4 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₃₂O₂
Molecular Weight	328.5 g/mol
XLogP3	6.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	14
Exact Mass	328.240230259 g/mol
Monoisotopic Mass	328.240230259 g/mol
Topological Polar Surface Area	37.3 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	462
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	6
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Indication

Used as a high-docosahexaenoic acid (DHA) oral supplement.

Treatment of Retinitis Pigmentosa

5 Pharmacology and Biochemistry

5.1 Pharmacology

DHA in the central nervous system is found in the phospholipid bilayers where it modulates the physical environment and increase the free volume within the membrane bilayer. It influences the G-protein coupled receptor activity and affects transmembrane transport and cell interaction with the exterior world. It is also reported to promote apoptosis, neuronal differentiation and ion channel activity. Like other polyunsaturated fatty acids, DHA acts as a ligand at PPARs that plays an anti-inflammatory effect and regulate inflammatory gene expression and NFB activation. DHA also gives rise to resolvins and related compounds (e.g., protectins) through pathways involving cyclooxygenase and lipoxygenase enzymes to resolve the inflammatory responses.

5.2 Absorption, Distribution and Excretion

Absorption

Like other omega-3 fatty acids, DHA is hydrolyzed from the intestines and delivered through the lymphatic circulation. Plasma DHA concentrations increase in a dose-dependent and saturable manner.

Volume of Distribution

DHA is the most abundant n3 fatty acid in membranes and is present in all organs. It is also the most variable among organs and is particularly abundant in neural tissue, such as brain and retina, where it is several hundred-fold more abundant than EPA.

5.3 Metabolism/Metabolites

DHA can be metabolized into DHA-derived specialized pro-resolving mediators (SPMs), DHA epoxides, electrophilic oxo-derivatives (EFOX) of DHA, neuroprostanes, ethanolamines, acylglycerols, docosahexaenoyl amides of amino acids or neurotransmitters, and branched DHA esters of hydroxy fatty acids, among others. It is converted to 17-hydroperoxy-DHA derivatives via COX-2 and 15-LOX and 5-LOX activity. These derivatives are further converted into D-series resolvins and protectins with potent anti-inflammatory potential and potent neuroprotective effect. DHA may also be metabolized to 19,20-epoxydocosapentaenoic acids (EDPs) and isomers via CYP2C9 activity. Epoxy metabolites are reported to mediate anti-tumor activity by inhibiting angiogenesis, tumor growth, and metastasis.

5.4 Biological Half-Life

Approximately 20 hours.

5.5 Mechanism of Action

DHA and its conversion to other lipid signalling moleccules compete with the arachidonic acid cascade from endogenous phospholipids and shift the inflammatory state to being more anti-inflammatory. DHA inhibits endotoxin-stimulated production of IL-6 and IL-8 in human endothelial cells. Derivatives of DHA are anti-inflammatory lipid mediators. Lipid mediators resolvin D1 and protectin D1 all inhibit transendothelial migration of neutrophils, so preventing neutrophilic infiltration at sites of inflammation, resolvin D1 inhibits IL-1 production, and protectin D1 inhibits TNF and IL-1 production. Monoxydroxy derivative of DHA converted by LOX inhibit thromboxane-induced platelet aggregation. DHA supplementation has also shown to reduce the levels of serum C-reactive protein (CRP) and other circulating markers of inflammation such as neutrophils in hypertriglyceridemic men. DHA acts as a ligand at peroxisome proliferator-activated receptor (PPAR) gamma and alpha that regulate lipid signalling molecule-mediated transduction pathways and modulate inflammation. As a natural ligand, DHA induces a protective effect in retinal tissues by activating retinoid x receptors and subsequent ERK/MAPK signaling pathway in photoreceptors to promote their survival and differentiation, stimulating the expression of antiapoptotic proteins such as Bcl-2 and preserving mitochondrial membrane potential.

API SUPPLIERS

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USDMF

01

Ak And Mn Biofarm Co Ltd

South Korea

PharmaVenue

Not Confirmed

02

Basf Pharma Callanish Ltd

Country

PharmaVenue

Not Confirmed

03

Chemport Inc

United Kingdom

PharmaVenue

Not Confirmed

04

Skuny Bioscience Co Ltd

China

PharmaVenue

Not Confirmed

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Listed Suppliers

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API Reference Price

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SHAANXI POINEER BIOTEC CO,LTD","supplierCountry":"CHINA","foreign_port":"NA","customer":"AURIGENE PHARMACEUTICAL SERVICES","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"400","totalValueFC":"401.7","currency":"USD","unitRateINR":"30094.8","date":"06-Oct-2021","totalValueINR":"30094.8","totalValueInUsd":"401.7","indian_port":"BANGALORE AIR","hs_no":"29339990","bill_no":"5727420","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"39-40 KIADB INDUSTRIAL AREA,ELECTR ONIC CITY PHASE II HOSUR ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1641407400,"product":"DRY N-3(R) DHA 11A [DOCOSAHEXAENOIC ACID]","address":"F6 SHAGUN ARCADE GEN AK VAIDYA MAR G,DINDOSHI MALAD EAST","city":"MUMBAI,MAHARASHTRA","supplier":"BASF","supplierCountry":"DENMARK","foreign_port":"#N\/A","customer":"ATLANTIC CHEMICALS TRADING","customerCountry":"INDIA","quantity":"2600.00","actualQuantity":"2600","unit":"KGS","unitRateFc":"23.5","totalValueFC":"104811.9","currency":"USD","unitRateINR":"3003","date":"06-Jan-2022","totalValueINR":"7807800","totalValueInUsd":"104811.9","indian_port":"JNPT","hs_no":"29161990","bill_no":"6978962","productDescription":"API","marketType":"REGULATED MARKET","country":"DENMARK","selfForZScoreResived":"Pharma Grade","supplierPort":"#N\/A","supplierAddress":"","customerAddress":"F6 SHAGUN ARCADE GEN AK VAIDYA MAR G,DINDOSHI MALAD EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1667413800,"product":"DOCOSAHEXAENOIC ACID (OTHER ORGANO COMPOUND)BATCH NO. DDH2210003","address":"A-1\/2,MAHENDRU ENCLAVE G T KARNAL ROAD","city":"DELHI,DELHI","supplier":"HANGZHOU XUANDA BIOTECHNOLOGY ","supplierCountry":"CHINA","foreign_port":"NA","customer":"CORAL ORGANICALS","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"38.5","totalValueFC":"3957.9","currency":"USD","unitRateINR":"3230.2","date":"03-Nov-2022","totalValueINR":"323015","totalValueInUsd":"3957.9","indian_port":"DELHI AIR","hs_no":"29319090","bill_no":"3144690","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"A-1\/2,MAHENDRU ENCLAVE G T KARNAL ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1671474600,"product":"DHA OIL (DOCOSAHEXAENOIC ACID OIL 40%)","address":"PLOT NO 4 GROUND FLOOR KH NO-1050 ,MAIN ROAD BHALSWA VILLAGE","city":"NEW DELHI,DELHI","supplier":"QUANZHOU FORTUNE TRADE ","supplierCountry":"CHINA","foreign_port":"NA","customer":"HERBOSYNTH INDIA","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"35","totalValueFC":"3548.6","currency":"USD","unitRateINR":"2924.3","date":"20-Dec-2022","totalValueINR":"292425","totalValueInUsd":"3548.6","indian_port":"DELHI AIR","hs_no":"29161990","bill_no":"3821826","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"PLOT NO 4 GROUND FLOOR KH NO-1050 ,MAIN ROAD BHALSWA VILLAGE"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1682620200,"product":"DOCOSAHEXAENOIC ACID (OTHER ORGANIC COMPOUN)","address":"A-4\/603 KRISHNA APRA GARDEN STORE, NO R\/25 VAIBHAV KHAND INDRAPURAM","city":"GHAZIABAD,UTTAR PRADESH","supplier":"GTX EXPORTS","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"MAGIK RETAIL","customerCountry":"INDIA","quantity":"280.00","actualQuantity":"280","unit":"KGS","unitRateFc":"41.1","totalValueFC":"11683.1","currency":"USD","unitRateINR":"3419.5","date":"28-Apr-2023","totalValueINR":"957472.25","totalValueInUsd":"11683.1","indian_port":"DELHI AIR","hs_no":"29319090","bill_no":"5727599","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"A-4\/603 KRISHNA APRA GARDEN STORE, NO R\/25 VAIBHAV KHAND INDRAPURAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1719858600,"product":"DOCOSAHEXAENOIC ACID (OTHER ORGANO COMPOUND)","address":"A-4\/603 KRISHNA APRA GARDEN STORE,","city":"GHAZIABAD,UTTAR PRADESH","supplier":"GTX EXPORTS","supplierCountry":"UNITED STATES","foreign_port":"ATLANTA, HARTSFIELD","customer":"MAGIK RETAIL","customerCountry":"INDIA","quantity":"800.00","actualQuantity":"800","unit":"KGS","unitRateFc":"26.3","totalValueFC":"22964.2","currency":"USD","unitRateINR":"2399.5","date":"02-Jul-2024","totalValueINR":"1919606.26","totalValueInUsd":"22964.2","indian_port":"Delhi Air","hs_no":"29319090","bill_no":"4283392","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"ATLANTA, HARTSFIELD","supplierAddress":"6207 W HILLSBOROUGHB AV UNIT E 10TAMPA FL 33634 UNITED STATESSDNF SDNF","customerAddress":"A-4\/603 KRISHNA APRA GARDEN STORE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727461800,"product":"DOCOSAHEXAENOIC ACID (OTHER ORGANIC COMPOUND)","address":"A-4\/603 KRISHNA APRA GARDEN STORE,","city":"GHAZIABAD,UTTAR PRADESH","supplier":"GTX EXPORTS","supplierCountry":"UNITED STATES","foreign_port":"ATLANTA, HARTSFIELD","customer":"MAGIK RETAIL","customerCountry":"INDIA","quantity":"800.00","actualQuantity":"800","unit":"KGS","unitRateFc":"26.2","totalValueFC":"22906.4","currency":"USD","unitRateINR":"2399.5","date":"28-Sep-2024","totalValueINR":"1919585","totalValueInUsd":"22906.4","indian_port":"Delhi Air","hs_no":"29319090","bill_no":"5852273","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"ATLANTA, HARTSFIELD","supplierAddress":"6207 W HILLSBOROUGHB AV UNIT E 10 TAMPA FL 33634 UNITED STATES SDNF SDNF","customerAddress":"A-4\/603 KRISHNA APRA GARDEN STORE,"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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Drugs in Development

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Bernofarm Pharmaceutical Company

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Analytical Methods

ABOUT THIS PAGE

Docosahexaenoic Acid Manufacturers

A Docosahexaenoic Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Docosahexaenoic Acid, including repackagers and relabelers. The FDA regulates Docosahexaenoic Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Docosahexaenoic Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Docosahexaenoic Acid manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Docosahexaenoic Acid Suppliers

A Docosahexaenoic Acid supplier is an individual or a company that provides Docosahexaenoic Acid active pharmaceutical ingredient (API) or Docosahexaenoic Acid finished formulations upon request. The Docosahexaenoic Acid suppliers may include Docosahexaenoic Acid API manufacturers, exporters, distributors and traders.

click here to find a list of Docosahexaenoic Acid suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Docosahexaenoic Acid USDMF

A Docosahexaenoic Acid DMF (Drug Master File) is a document detailing the whole manufacturing process of Docosahexaenoic Acid active pharmaceutical ingredient (API) in detail. Different forms of Docosahexaenoic Acid DMFs exist exist since differing nations have different regulations, such as Docosahexaenoic Acid USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Docosahexaenoic Acid DMF submitted to regulatory agencies in the US is known as a USDMF. Docosahexaenoic Acid USDMF includes data on Docosahexaenoic Acid's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Docosahexaenoic Acid USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Docosahexaenoic Acid suppliers with USDMF on PharmaCompass.

Docosahexaenoic Acid GMP

Docosahexaenoic Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Docosahexaenoic Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Docosahexaenoic Acid GMP manufacturer or Docosahexaenoic Acid GMP API supplier for your needs.

Docosahexaenoic Acid CoA

A Docosahexaenoic Acid CoA (Certificate of Analysis) is a formal document that attests to Docosahexaenoic Acid's compliance with Docosahexaenoic Acid specifications and serves as a tool for batch-level quality control.

Docosahexaenoic Acid CoA mostly includes findings from lab analyses of a specific batch. For each Docosahexaenoic Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Docosahexaenoic Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (Docosahexaenoic Acid EP), Docosahexaenoic Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Docosahexaenoic Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

11 API Suppliers

4 USDMF

7 Listed Suppliers

$ API Reference Price

DEVELOPMENTS

5 Drugs in Development

FINISHED DOSAGE FORMULATIONS

23 FDF Dossiers

23 Listed Dossiers

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EXCIPIENTS BY APPLICATIONS

76 Fillers, Diluents & Binders

56 Coating Systems & Additives

37 Direct Compression

34 Controlled & Modified Release

30 Thickeners and Stabilizers

28 Solubilizers

26 Taste Masking

24 Parenteral

22 Film Formers & Plasticizers

22 Disintegrants & Superdisintegrants

22 Granulation

20 Topical

19 Co-Processed Excipients

17 Chewable & Orodispersible Aids

16 Lubricants & Glidants

13 Emulsifying Agents

9 Empty Capsules

8 API Stability Enhancers