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Docusate Potassium

Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

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ACTIVE PHARMA INGREDIENTS

7 API Suppliers, 3 USDMF, 3 NDC API, 4 Listed Suppliers

7 API Suppliers
3 USDMF
3 NDC API
4 Listed Suppliers

DEVELOPMENTS

1 Drugs in Development

1 Drugs in Development

FINISHED DOSAGE FORMULATIONS

19 FDF Dossiers, 1 Europe, 14 Canada, 2 Australia, 2 Listed Dossiers

19 FDF Dossiers
1 Europe
14 Canada
2 Australia
2 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 Evonik, 10 Rochem International Inc, 20 SPI Pharma, 2 Seqens, 13 DKSH, 2 Jai Radhe Sales, 2 Pharm-RX Chemical, 9 Faran Shimi Pharmaceutical, 4 Boai NKY Pharmaceuticals Ltd, 13 Gangwal Healthcare, 2 Kewpie Corporation, 11 Nanjing Well Pharmaceutical, 2 Pfanstiehl, 4 ACG Worldwide, 13 Actylis, 2 Aeon Procare, 8 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 1 Avesta Pharma, 32 BASF, 1 Bioplus Life Sciences, 3 Clariant, 13 Corel Pharma Chem, 3 DFE Pharma, 3 Doshion Polyscience, 2 Finar, 13 Gangwal Chemicals, 7 Ideal Cures Pvt Ltd, 4 Ingredion Pharma Solutions, 19 Kerry, 5 Kima Chemical, 6 Lonza Capsugel, 17 Microlex e.U, 2 Nanjing Bold Chemical, 2 Nomisma Healthcare, 3 Novo Excipients, 2 Pharmatrans-Sanaq, 11 Pluviaendo, 4 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 2 Qualicaps, 35 Roquette, 14 Seppic, 7 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 2 Shijiazhuang Huaxu Pharmaceutical, 10 Sigachi Industries, 4 The Dow Chemical Company, 2 Ulanqab Kema New Material, 2 Valens Pharmachem, 3 Vasa Pharmachem, 2 Zhejiang Huakang Pharmaceutical

relatedExcipients
1 Evonik
10 Rochem International Inc
20 SPI Pharma
2 Seqens
13 DKSH
2 Jai Radhe Sales
2 Pharm-RX Chemical
9 Faran Shimi Pharmaceutical
4 Boai NKY Pharmaceuticals Ltd
13 Gangwal Healthcare
2 Kewpie Corporation
11 Nanjing Well Pharmaceutical
2 Pfanstiehl
4 ACG Worldwide
13 Actylis
2 Aeon Procare
8 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
1 Avesta Pharma
32 BASF
1 Bioplus Life Sciences
3 Clariant
13 Corel Pharma Chem
3 DFE Pharma
3 Doshion Polyscience
2 Finar
13 Gangwal Chemicals
7 Ideal Cures Pvt Ltd
4 Ingredion Pharma Solutions
19 Kerry
5 Kima Chemical
6 Lonza Capsugel
17 Microlex e.U
2 Nanjing Bold Chemical
2 Nomisma Healthcare
3 Novo Excipients
2 Pharmatrans-Sanaq
11 Pluviaendo
4 Prachin Chemical
1 Qianhao Chemical (Hebei) Co., Ltd
2 Qualicaps
35 Roquette
14 Seppic
7 Shanghai Shenmei Pharmaceutical Technology Co., Ltd
1 Shanghai Welltone Material Technology Co., Ltd
2 Shijiazhuang Huaxu Pharmaceutical
10 Sigachi Industries
4 The Dow Chemical Company
2 Ulanqab Kema New Material
2 Valens Pharmachem
3 Vasa Pharmachem
2 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

91 Fillers, Diluents & Binders, 62 Coating Systems & Additives, 45 Thickeners and Stabilizers, 41 Direct Compression, 40 Taste Masking, 39 Solubilizers, 38 Controlled & Modified Release, 30 Topical, 30 Parenteral, 30 Film Formers & Plasticizers, 27 Granulation, 25 Disintegrants & Superdisintegrants, 24 Lubricants & Glidants, 19 Chewable & Orodispersible Aids, 19 Co-Processed Excipients, 14 Emulsifying Agents, 10 Rheology Modifiers, 10 API Stability Enhancers, 9 Empty Capsules, 5 Coloring Agents, 5 Surfactant & Foaming Agents, 4 Vegetarian Capsules, 1 Soft Gelatin

DIGITAL CONTENT

11 NEWS #PharmaBuzz

media
11 NEWS #PharmaBuzz

MARKET PLACE

10 APIs, 1 EXCIPIENTS

marketPlace
10 APIs
1 EXCIPIENTS

REF. STANDARDS & IMPURITIES

1 EDQM , 3 USP , 1 Others

otherSolutions
1 EDQM
3 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

1DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

356 RELATED EXCIPIENT COMPANIES

618EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 7491-09-0, Rectalad enema, Rectalad, Dioctyl potassium sulfosuccinate, Cik9f54zhr, Potassium;1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate

Molecular Formula

C₂₀H₃₇KO₇S

Molecular Weight

460.7 g/mol

InChI Key

CACRHRQTJDKAPJ-UHFFFAOYSA-M

FDA UNII

CIK9F54ZHR

All-purpose surfactant, wetting agent, and solubilizer used in the drug, cosmetics, and food industries. It has also been used in laxatives and as cerumenolytics. It is usually administered as either the calcium, potassium, or sodium salt.

1 2D Structure

Docusate Potassium

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

potassium;1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate

2.1.2 InChI

InChI=1S/C20H38O7S.K/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2;/h16-18H,5-15H2,1-4H3,(H,23,24,25);/q;+1/p-1

2.1.3 InChI Key

CACRHRQTJDKAPJ-UHFFFAOYSA-M

2.1.4 Canonical SMILES

CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)[O-].[K+]

2.2 Other Identifiers

2.2.1 UNII

CIK9F54ZHR

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Aerosol Ot

2. Colace

3. Deh Na Ss

4. Deh-na-ss

5. Diethylhexyl Sodium Sulfosuccinate

6. Dioctyl Sulfosuccinate

7. Dioctyl Sulfosuccinate, Sodium

8. Dioctyl Sulfosuccinates

9. Dioctyl Sulfosuccinic Acid

10. Dioctyl Sulfosuccinic Acid, Ammonium Salt

11. Dioctyl Sulfosuccinic Acid, Barium Salt

12. Dioctyl Sulfosuccinic Acid, Calcium Salt

13. Dioctyl Sulfosuccinic Acid, Magnesium Salt

14. Dioctyl Sulfosuccinic Acid, Potassium Salt

15. Dioctyl Sulfosuccinic Acid, Sodium Salt

16. Dioctylsulfosuccinate

17. Dioctylsulphosuccinate, Sodium

18. Docusate

19. Docusate Calcium

20. Docusate Sodium

21. Doss

22. Sodium Bis(2-ethylhexyl)sulfosuccinate

23. Sodium Dioctyl Sulfosuccinate

24. Sodium Dioctylsulphosuccinate

25. Sodium Sulfosuccinate, Diethylhexyl

26. Sulfosuccinate, Diethylhexyl Sodium

27. Sulfosuccinate, Dioctyl

28. Sulfosuccinates, Dioctyl

29. Sulfosuccinic Acid Bis(2-ethylhexyl) Ester

2.3.2 Depositor-Supplied Synonyms

1. 7491-09-0

2. Rectalad Enema

3. Rectalad

4. Dioctyl Potassium Sulfosuccinate

5. Cik9f54zhr

6. Potassium;1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate

7. Potassium 1,4-bis(2-ethylhexyl) Sulfosuccinate

8. Butanedioic Acid, Sulfo-, 1,4-bis(2-ethylhexyl) Ester, Potassium Salt

9. Potassium 1,4-bis((2-ethylhexyl)oxy)-1,4-dioxobutane-2-sulfonate

10. Potassium 1,2-bis(2-ethylhexyloxycarbonyl)ethanesulfonate

11. Docusat Kalium

12. Potassium 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonate

13. Dioctylkaliumsulfosuccinat

14. Unii-cik9f54zhr

15. Docusate Potassium [usan]

16. Docusate Potassium [usan:usp]

17. Einecs 231-308-5

18. Rectalad Enema (tn)

19. Potassium 1,2-bis(2-ethylhexyloxycarbonyl)ethanesulphonate

20. Docusate Potassium (usp)

21. Ec 231-308-5

22. Schembl61043

23. Docusate Potassium [mi]

24. Chembl2107648

25. Dtxsid60996394

26. Docusate Potassium [vandf]

27. Docusate Potassium [mart.]

28. Docusate Potassium [usp-rs]

29. Docusate Potassium [who-dd]

30. Akos037645443

31. As-60792

32. Docusate Potassium [usp Monograph]

33. Cs-0455423

34. D03886

35. D93009

36. Bis(2-ethylhexyl) Sulfosuccinate Potassium Salt

37. Q27275483

2.4 Create Date

2008-02-05

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₃₇KO₇S
Molecular Weight	460.7 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	18
Exact Mass	460.18970617 g/mol
Monoisotopic Mass	460.18970617 g/mol
Topological Polar Surface Area	118 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	546
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	3
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Surface-Active Agents

Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics. (See all compounds classified as Surface-Active Agents.)

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