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    Chemistry

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    Also known as: 57808-66-9, Motilium, Nauzelin, Domperidonum, Domperidona, C22h24cln5o2
    Molecular Formula
    C22H24ClN5O2
    Molecular Weight
    425.9  g/mol
    InChI Key
    FGXWKSZFVQUSTL-UHFFFAOYSA-N
    FDA UNII
    5587267Z69
    Domperidone
    A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
    1 2D Structure

    Domperidone

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
    2.1.2 InChI
    InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)
    2.1.3 InChI Key
    FGXWKSZFVQUSTL-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O
    2.2 Other Identifiers
    2.2.1 UNII
    5587267Z69
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Apo Domperidone

    2. Apo-domperidone

    3. Domidon

    4. Domperidon

    5. Domperidon Al

    6. Domperidon Hexal

    7. Domperidon Stada

    8. Domperidon Teva

    9. Domperidon-teva

    10. Domperidona Gamir

    11. Domperidone Maleate

    12. Domperidone Maleate (1:1)

    13. Domperidone Monohydrochloride

    14. Gamir, Domperidona

    15. Gastrocure

    16. Hexal, Domperidon

    17. Maleate, Domperidone

    18. Monohydrochloride, Domperidone

    19. Motilium

    20. Nauzelin

    21. Novo Domperidone

    22. Novo-domperidone

    23. Nu Domperidone

    24. Nu-domperidone

    25. Pridys

    26. Pms Domperidone

    27. Pms-domperidone

    28. R-33,812

    29. R-33812

    30. R33,812

    31. R33812

    32. Ratio Domperidone

    33. Ratio-domperidone

    34. Stada, Domperidon

    2.3.2 Depositor-Supplied Synonyms

    1. 57808-66-9

    2. Motilium

    3. Nauzelin

    4. Domperidonum

    5. Domperidona

    6. C22h24cln5o2

    7. R-33812

    8. R 33,812

    9. 4-(5-chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine

    10. Nsc299589

    11. Nsc-299589

    12. 5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone

    13. Domperidone (motilium)

    14. R33812

    15. Nsc-759575

    16. Kw 5338

    17. 6-chloro-3-[1-[3-(2-oxo-3h-benzimidazol-1-yl)propyl]piperidin-4-yl]-1h-benzimidazol-2-one

    18. Mls000069343

    19. Chembl219916

    20. Chebi:31515

    21. Nsc 299589

    22. 2h-benzimidazol-2-one, 5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1h-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-

    23. 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1h-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2h-benzimidazol-2-one

    24. 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1h-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2h-benzimidazol-2-one

    25. Motinorm

    26. Costi

    27. 5-chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone

    28. Dsstox_cid_25116

    29. Dsstox_rid_80682

    30. Dsstox_gsid_45116

    31. 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1h-benzo[d]imidazol-2(3h)-one

    32. 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1h-benzo[d]imidazol-2(3h)-one

    33. 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1h-benzo[d]imidazol-2(3h)-one

    34. 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1h-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1h-1,3-benzodiazol-2-one

    35. 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one

    36. Domperidonum [inn-latin]

    37. Domperidona [inn-spanish]

    38. 5587267z69

    39. Motillium

    40. Motilium (tn)

    41. Smr000326802

    42. Cas-57808-66-9

    43. Kw-5338

    44. Lopac-d-122

    45. Sr-01000003002

    46. Einecs 260-968-7

    47. Brn 0903774

    48. Nauzelin Od

    49. Domperidone,(s)

    50. 5-chloro-1-{1-[3-(2,3-dihydro-2-oxo-1h-benzimidazol-1-yl)propyl]-4-piperidinyl}-1,3-dihydro-2h-benzimidazol-2-one

    51. Domperidone [usan:inn:ban:jan]

    52. Prestwick_794

    53. Mfcd00069256

    54. Nci299589

    55. Unii-5587267z69

    56. Hs-0067

    57. Spectrum_000391

    58. Opera_id_616

    59. Specplus_000825

    60. Domperidone [mi]

    61. Prestwick0_000461

    62. Prestwick1_000461

    63. Prestwick2_000461

    64. Prestwick3_000461

    65. Spectrum4_000087

    66. Domperidone [inn]

    67. Domperidone [jan]

    68. Domperidone [usan]

    69. Biomol-nt_000022

    70. Domperidone - Pharma Grade

    71. Domperidone [vandf]

    72. Ncistruc1_001686

    73. Ncistruc2_001819

    74. Domperidone [mart.]

    75. Lopac0_000427

    76. Schembl43729

    77. Bspbio_002350

    78. Domperidone [who-dd]

    79. Gtpl965

    80. Kbiogr_000354

    81. Kbioss_000871

    82. 5-24-02-00402 (beilstein Handbook Reference)

    83. Mls000859942

    84. Mls001306482

    85. Mls002222324

    86. Divk1c_006921

    87. Spectrum2300212

    88. Spbio_002501

    89. Bpbio1_000620

    90. Bpbio1_001185

    91. Domperidone [green Book]

    92. Dtxsid1045116

    93. Domperidone (jp17/usan/inn)

    94. Kbio1_001865

    95. Kbio2_000871

    96. Kbio2_003439

    97. Kbio2_006007

    98. Domperidone [ep Monograph]

    99. Hms1922n04

    100. Hms2089c14

    101. Hms2093n22

    102. Hms2096c21

    103. Hms2230n18

    104. Hms3261e16

    105. Hms3269o13

    106. Hms3370l03

    107. Hms3413f15

    108. Hms3656m21

    109. Hms3677f15

    110. Hms3713c21

    111. Hms3884n19

    112. Pharmakon1600-02300212

    113. Bcp28265

    114. Domperidone 1.0 Mg/ml In Methanol

    115. Hy-b0411

    116. Zinc4175569

    117. Tox21_110056

    118. Tox21_500427

    119. Bbl028136

    120. Bdbm50241107

    121. Ccg-37870

    122. Ncgc00014670

    123. Nsc759575

    124. S2461

    125. Stk622843

    126. Akos005555858

    127. Tox21_110056_1

    128. Ac-2037

    129. Db01184

    130. Domperidone, Powder, >=98% (hplc)

    131. Lp00427

    132. Nsc 759575

    133. Sdccgsbi-0050412.p004

    134. Ncgc00014670-01

    135. Ncgc00014670-02

    136. Ncgc00014670-03

    137. Ncgc00014670-04

    138. Ncgc00014670-05

    139. Ncgc00014670-06

    140. Ncgc00014670-07

    141. Ncgc00014670-08

    142. Ncgc00014670-09

    143. Ncgc00014670-10

    144. Ncgc00014670-11

    145. Ncgc00014670-12

    146. Ncgc00014670-13

    147. Ncgc00014670-14

    148. Ncgc00014670-16

    149. Ncgc00014670-17

    150. Ncgc00014670-28

    151. Ncgc00015306-01

    152. Ncgc00021472-02

    153. Ncgc00021472-03

    154. Ncgc00021472-04

    155. Ncgc00021472-05

    156. Ncgc00021472-06

    157. Ncgc00021472-07

    158. Ncgc00021472-08

    159. Ncgc00097773-01

    160. Ncgc00261112-01

    161. 2h-benzimidazol-2-one, 1,3-dihydro-5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1h-benzimidazol-1-yl)propyl)-4-piperidinyl)-

    162. 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1h-benzimidazol-1-yl)propyl)-4-piperidinyl)-1,3-dihydro-2h-benzimidazol-2-one

    163. 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1,3-dihydro-2h-benzo[d]imidazol-2-one

    164. Bd164379

    165. Nci60_002512

    166. Smr000058969

    167. Ab00052423

    168. D4125

    169. Eu-0100427

    170. Ft-0625588

    171. Sw196931-3

    172. C75710

    173. D01745

    174. Ab00052423-06

    175. Ab00052423-07

    176. Ab00052423_08

    177. Ab00052423_09

    178. 808d669

    179. A831618

    180. L000230

    181. Q424238

    182. R 33812

    183. Sr-01000003002-2

    184. Sr-01000003002-4

    185. Sr-01000003002-7

    186. W-105440

    187. Brd-k38305202-001-02-6

    188. Brd-k38305202-001-08-3

    189. Domperidone, European Pharmacopoeia (ep) Reference Standard

    190. 5-chloro-1-[1-[3-(2-oxo-1-benzimidazolyl)propyl]-4-piperidyl]benzimidazol-2-one

    191. 1h-benzimidazol-2-ol, 5-chloro-1-[1-[3-(2-hydroxy-1h-benzimidazol-1-yl)propyl]-4-piperidinyl]-

    192. 2h-benzimidazol-2-one,3-dihydro-2-oxo-1h-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-

    193. 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo -1h-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-d Ihydro-2h-benzimidazol-2-one

    194. 5-chloro-1-{1-[3-(1,3-dihydro-2-oxo-2h-benzimidazol-1-yl)propyl]-4-piperidinyl}-1,3-dihydro-2h-benzimidazol-2-one

    195. 5-chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1h-benzoimidazol-2-ol

    196. 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)

    197. 6-chloro-3-[1-[3-(2-oxo-3a,7a-dihydro-3h-benzimidazol-1-yl)propyl]-4-piperidyl]-3a,7a-dihydro-1h-benzimidazol-2-one

    198. Domperidone5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one

    2.4 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 425.9 g/mol
    Molecular Formula C22H24ClN5O2
    XLogP33.9
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count5
    Exact Mass425.1618527 g/mol
    Monoisotopic Mass425.1618527 g/mol
    Topological Polar Surface Area67.9 Ų
    Heavy Atom Count30
    Formal Charge0
    Complexity655
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Indication

    For management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Domperidone is a specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.

    5.2 MeSH Pharmacological Classification

    Antiemetics

    Drugs used to prevent NAUSEA or VOMITING. (See all compounds classified as Antiemetics.)

    Dopamine Antagonists

    Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. (See all compounds classified as Dopamine Antagonists.)

    5.3 ATC Code

    A03FA03

    S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

    A - Alimentary tract and metabolism

    A03 - Drugs for functional gastrointestinal disorders

    A03F - Propulsives

    A03FA - Propulsives

    A03FA03 - Domperidone

    5.4 Metabolism/Metabolites

    Domperidone has known human metabolites that include 1-Propyl-1,3-dihydro-2H-benzimidazol-2-one, 3-[3-[4-(5-Chloro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-6-hydroxy-1H-benzimidazol-2-one, and 5-Chloro-1-(piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one.

    S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560

    5.5 Biological Half-Life

    7 hours

    5.6 Mechanism of Action

    Domperidone acts as a gastrointestinal emptying (delayed) adjunct and peristaltic stimulant. The gastroprokinetic properties of domperidone are related to its peripheral dopamine receptor blocking properties. Domperidone facilitates gastric emptying and decreases small bowel transit time by increasing esophageal and gastric peristalsis and by lowering esophageal sphincter pressure. Antiemetic: The antiemetic properties of domperidone are related to its dopamine receptor blocking activity at both the chemoreceptor trigger zone and at the gastric level. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which - among others - regulates nausea and vomiting

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    USDMF CEP/COS JDMF EU-WCInactive-api
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    Date of Issue : 2023-02-14

    Valid Till : 2024-02-26

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    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 24424

    Submission : 2010-12-13

    Status : Active

    Type : II

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    Certificate Number : R1-CEP 1997-094 - Rev 09

    Issue Date : 2019-11-12

    Type : Chemical

    Substance Number : 1009

    Status : Valid

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    Registration Number : 227MF10272

    Registrant's Address : C-4, Industrial Area, Uppal Khalsa (V), Uppal (M), Medchal-Malkajgiri (Dist.), Hyderabad-500039. Telangana, India.

    Initial Date of Registration : 2015-12-01

    Latest Date of Registration : --

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    NDC Package Code : 66326-101

    Start Marketing Date : 2020-01-20

    End Marketing Date : 2024-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

     KDMF arrow-down
    ✖

    Registrant Name : Cheongsol Biotech Co., Ltd.

    Registration Date : 2007-12-28

    Registration Number : 20071228-79-D-68-02

    Manufacturer Name : SRI KRISHNA Pharmaceuticals limited

    Manufacturer Address : C-4 industrial area uppal hydrabad-500039

     VMF Others AUDIT
    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

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    06

    Johnson & Johnson Innovative Medic...

    U.S.A

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    ASC 2024
    Not Confirmed
    arrow

    Johnson & Johnson Innovative Medic...

    U.S.A

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    ASC 2024
    Not Confirmed
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 5402

    Submission : 1984-05-17

    Status : Inactive

    Type : II

     CEP/COS arrow-down
    ✖

    Certificate Number : R1-CEP 1996-069 - Rev 10

    Issue Date : 2019-10-22

    Type : Chemical

    Substance Number : 1009

    Status : Valid

     JDMF arrow-down
    ✖

    Registration Number : 218MF10687

    Registrant's Address : Turnhoutseweg 30 B-2340 Beerse Belgium

    Initial Date of Registration : 2006-08-11

    Latest Date of Registration : --

     EU-WC NDC KDMF VMF Others AUDIT
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    07

    Vasudha Pharma Chem

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    ASC 2024
    Not Confirmed
    arrow

    Vasudha Pharma Chem

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    ASC 2024
    Not Confirmed
    USDMF CEP/COS arrow-down
    ✖

    Certificate Number : R0-CEP 2020-315 - Rev 01

    Issue Date : 2023-01-31

    Type : Chemical

    Substance Number : 1009

    Status : Valid

     JDMF arrow-down
    ✖

    Registration Number : 304MF10034

    Registrant's Address : 78/A, Bengalrao Nagar, Hyderabad-500 038, Telangana State, India.

    Initial Date of Registration : 2022-02-10

    Latest Date of Registration : --

     EU-WCarrow-down
    ✖

    Date of Issue : 2022-06-15

    Valid Till : 2025-07-14

    Written Confirmation Number : WC-0183nA2

    Address of the Firm :

    NDC KDMF arrow-down
    ✖

    Registrant Name : Daeshin Pharmaceutical Co., Ltd.

    Registration Date : 2023-06-22

    Registration Number : 20230111-11-B-472-07(1)

    Manufacturer Name : Vasudha Pharma Chem Limited

    Manufacturer Address : Unit-II, Plot No. 79, Jawaharlal Nehru Pharma City, Thanam(V), Parawada, Visakhapatnam District - 531019 Andhra Pradesh, India

     VMF Others AUDIT
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    08

    Vasudha Pharma Chem

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    ASC 2024
    Not Confirmed
    arrow

    Vasudha Pharma Chem

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    ASC 2024
    Not Confirmed
    USDMF CEP/COS arrow-down
    ✖

    Certificate Number : R1-CEP 2007-203 - Rev 04

    Issue Date : 2020-09-03

    Type : Chemical

    Substance Number : 1009

    Status : Valid

     JDMF arrow-down
    ✖

    Registration Number : 220MF10225

    Registrant's Address : 78/A,Vengalrao Nagar,Hyderabad-500 038,Telangana State,INDIA

    Initial Date of Registration : 2008-11-10

    Latest Date of Registration : --

     EU-WCarrow-down
    ✖

    Date of Issue : 2022-06-14

    Valid Till : 2025-07-04

    Written Confirmation Number : WC-0070

    Address of the Firm :

    NDC KDMF arrow-down
    ✖

    Registrant Name : Daeshin Pharmaceutical Co., Ltd.

    Registration Date : 2023-06-22

    Registration Number : 20230111-11-B-472-07(1)

    Manufacturer Name : Vasudha Pharma Chem Limited

    Manufacturer Address : Unit-II, Plot No. 79, Jawaharlal Nehru Pharma City, Thanam(V), Parawada, Visakhapatnam District - 531019 Andhra Pradesh, India

     VMF Others AUDIT
    blank

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    09

    Sri Krishna Pharmaceuticals

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    ASC 2024
    Not Confirmed
    arrow

    Sri Krishna Pharmaceuticals

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    ASC 2024
    Not Confirmed
    USDMF CEP/COS arrow-down
    ✖

    Certificate Number : R0-CEP 2022-374 - Rev 00

    Issue Date : 2023-01-16

    Type : Chemical

    Substance Number : 1009

    Status : Valid

     JDMF EU-WC NDC arrow-down
    ✖

    NDC Package Code : 66326-101

    Start Marketing Date : 2020-01-20

    End Marketing Date : 2024-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

     KDMF arrow-down
    ✖

    Registrant Name : Cheongsol Biotech Co., Ltd.

    Registration Date : 2007-12-28

    Registration Number : 20071228-79-D-68-02

    Manufacturer Name : SRI KRISHNA Pharmaceuticals limited

    Manufacturer Address : C-4 industrial area uppal hydrabad-500039

     VMF Others AUDIT
    blank

    Portfolio PDF

    Product Web Link

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    Digital Content

    Website

    Corporate PDF

    10

    Aurobindo Pharma Limited

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    ASC 2024
    Not Confirmed
    arrow

    Aurobindo Pharma Limited

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    ASC 2024
    Not Confirmed
    USDMF CEP/COS arrow-down
    ✖

    Certificate Number : CEP 2004-096 - Rev 05

    Issue Date : 2023-11-14

    Type : Chemical

    Substance Number : 1009

    Status : Valid

     JDMF arrow-down
    ✖

    Registration Number : 226MF10135

    Registrant's Address : Plot No. 2, Maitrivihar, Ameerpet, Hyderabad Andhra Pradesh, India

    Initial Date of Registration : 2014-07-02

    Latest Date of Registration : --

     EU-WCarrow-down
    ✖

    Date of Issue : 2022-06-06

    Valid Till : 2025-06-10

    Written Confirmation Number : WC-0017

    Address of the Firm :

    NDC KDMF VMF Others AUDIT
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    Only 10 entries up to this point, click to access all click full view read-more
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    Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

    USDMF

    read-more
    read-more

    01

    World Dairy Expo 2024
    Not Confirmed

    01

    Janssen Pharmaceutica Nv

    U.S.A
    arrow
    World Dairy Expo 2024
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 5402

    Submission : 1984-05-17

    Status : Inactive

    Type : II

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    02

    World Dairy Expo 2024
    Not Confirmed

    02

    Sri Krishna Pharmaceuticals Ltd

    India
    arrow
    World Dairy Expo 2024
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 24424

    Submission : 2010-12-13

    Status : Active

    Type : II

    blank

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    Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

    API Reference Price

    read-more
    read-more
    [{"dataSource":"API Export","activeIngredients":"DOMPERIDONE","year":"2021","qtr":"Q1","strtotime":1609525800,"product":"ACTIVE PHARMACEUTICAL INGREDIENT(2001261 106 DT.29.12.2020) DOMPERIDONE EP\/BP(GRO UP: B )(MEIS SLNO. 1434)","address":"78\/A,VENGALARAO NAGARHYDERABAD","city":"ANDHRA PRADESH","supplier":"VASUDHA PHARMA CHEM","supplierCountry":"INDIA","foreign_port":"SHANGHAI - PU DONG","customer":"TO THE ORDER OF","customerCountry":"CHINA","quantity":"2500.00","actualQuantity":"2500","unit":"KGS","unitRateFc":"146.8","totalValueFC":"371518.6","currency":"USD","unitRateINR":10868.67764,"date":"02-Jan-2021","totalValueINR":"27171694.1","totalValueInUsd":"371518.6","indian_port":"HYDERABAD AIR","hs_no":"29225024","bill_no":"7635453","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"78\/A,VENGALARAO NAGARHYDERABAD, ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE","year":"2021","qtr":"Q1","strtotime":1609871400,"product":"PANTAPROZOLE 40 MG + DOMPERIDONE 30MG PE LLETS BLEND BATCH NO-PD\/SF\/1061220 MFG DATE-2020\/12 EXP DATE-2023\/11","address":"PLOT NO. 59, G-3. SRI VENKATESWARATOWERS,BHAGYANAGAR COLONY","city":"KUKATPALLY OPP KPHB,HYDERABAD, A.P.","supplier":"SPANSULES FORMULATIONS","supplierCountry":"INDIA","foreign_port":"BIRGUNJ","customer":"SAMAR PHARMA COMPANY ","customerCountry":"NEPAL","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"33.1","totalValueFC":"3349.9","currency":"USD","unitRateINR":2450,"date":"06-Jan-2021","totalValueINR":"245000","totalValueInUsd":"3349.9","indian_port":"RAXAUL","hs_no":"29333990","bill_no":"7727512","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pellets","supplierPort":"RAXAUL","supplierAddress":"PLOT NO. 59, G-3. SRI VENKATESWARATOWERS,BHAGYANAGAR COLONY, KUKATPALLY OPP KPHB,HYDERABAD, A.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE","year":"2021","qtr":"Q1","strtotime":1610303400,"product":"PHARMACEUTICAL RAW MATERIAL (DOMPERIDONE B.P)","address":"OPPOSITE - POST OFFICE , DELHI GATE","city":"PALANPUR , GUJARAT","supplier":"B SHARDA PHARMA ","supplierCountry":"INDIA","foreign_port":"HONG KONG","customer":"HEIAN NET LTD","customerCountry":"HONG KONG","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"44.9","totalValueFC":"4547.4","currency":"USD","unitRateINR":3325.8000000000002,"date":"11-Jan-2021","totalValueINR":"332580","totalValueInUsd":"4547.4","indian_port":"AHMEDABAD AIR","hs_no":"29225024","bill_no":"7836446","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"HONG KONG","selfForZScoreResived":"Pharma Grade","supplierPort":"AHMEDABAD AIR","supplierAddress":"OPPOSITE - POST OFFICE , DELHI GATE, PALANPUR , GUJARAT","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE MALEATE","year":"2021","qtr":"Q1","strtotime":1610562600,"product":"DOMPERIDONE MALEATE BP 2019","address":"B-312, KNOX PLAZA,OFF LINK ROAD, NEAR MIND SPACE,NEXT TO TANGENT SHOWROOM MALAD-W","city":"MUMBAI","supplier":"DARNAX PHARMA PRIVATE ","supplierCountry":"INDIA","foreign_port":"HO CHI MINH CITY","customer":"TO ORDER","customerCountry":"VIETNAM","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"60.4","totalValueFC":"30596.9","currency":"USD","unitRateINR":4475.5185999999994,"date":"14-Jan-2021","totalValueINR":"2237759.3","totalValueInUsd":"30596.9","indian_port":"JNPT","hs_no":"29225090","bill_no":"7904228","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"VIETNAM, DEMOCRATIC REP. OF","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"B-312, KNOX PLAZA,OFF LINK ROAD, NEAR MIND SPACE,NEXT TO TANGENT SHOWROOM MALAD-W, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE MALEATE","year":"2021","qtr":"Q1","strtotime":1610821800,"product":"DOMPERIDONE MALEATE","address":"44-FAIZ-E-EDROOS,371-373 NARSI NATHA STREET,MASJID BUNDER","city":"MUMBAI ,MAHARASHTRA","supplier":"JAYANA PHARMA","supplierCountry":"INDIA","foreign_port":".NEPAL","customer":"PANAS PHARMACEUTICALS PVT ","customerCountry":"NEPAL","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"59.5","totalValueFC":"602.6","currency":"USD","unitRateINR":4407.4160000000002,"date":"17-Jan-2021","totalValueINR":"44074.16","totalValueInUsd":"602.6","indian_port":"LCS Nepalgunj Road","hs_no":"29225024","bill_no":"7961802","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"NEPAL","selfForZScoreResived":"Pharma Grade","supplierPort":"LCS Nepalgunj Road","supplierAddress":"44-FAIZ-E-EDROOS,371-373 NARSI NATHA STREET,MASJID BUNDER, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE","year":"2021","qtr":"Q1","strtotime":1611167400,"product":"PHARMACEUTICALS RAW MATERIALS: 20012611 62 & 11.01.2021 DOMPERIDONE BP (GROUP:C) (MEIS SLNO.1434)","address":"78\/A,VENGALARAO NAGARHYDERABAD","city":"ANDHRA PRADESH","supplier":"VASUDHA PHARMA CHEM","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"TO THE ORDER OF.......","customerCountry":"BANGLADESH","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"59","totalValueFC":"1493.4","currency":"USD","unitRateINR":4369.04,"date":"21-Jan-2021","totalValueINR":"109226","totalValueInUsd":"1493.4","indian_port":"HYDERABAD AIR","hs_no":"29225024","bill_no":"8049632","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"78\/A,VENGALARAO NAGARHYDERABAD, ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE MALEATE","year":"2021","qtr":"Q1","strtotime":1611167400,"product":"ACTIVE PHARMACEUTICAL INGREDIENT(2001261 175 DT:18.01.2021) DOMPERIDONE MALEATE P H.EUR MEIS GROUP:B SL NO.1535","address":"78\/A,VENGALARAO NAGARHYDERABAD","city":"ANDHRA PRADESH","supplier":"VASUDHA PHARMA CHEM","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"TO THE ORDER OF","customerCountry":"TURKEY","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"175","totalValueFC":"8856.6","currency":"USD","unitRateINR":12954.857400000001,"date":"21-Jan-2021","totalValueINR":"647742.87","totalValueInUsd":"8856.6","indian_port":"HYDERABAD AIR","hs_no":"29225090","bill_no":"8058169","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"78\/A,VENGALARAO NAGARHYDERABAD, ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE MALEATE","year":"2021","qtr":"Q1","strtotime":1611167400,"product":"PHARMACEUTICALS RAW MATERIALS: 20012611 62 & 11.01.2021 DOMPERIDONE MALEATE BP ( GROUP:C)(MEIS SLNO.1435)","address":"78\/A,VENGALARAO NAGARHYDERABAD","city":"ANDHRA PRADESH","supplier":"VASUDHA PHARMA CHEM","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"TO THE ORDER OF.......","customerCountry":"BANGLADESH","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"59","totalValueFC":"5973.8","currency":"USD","unitRateINR":4369.04,"date":"21-Jan-2021","totalValueINR":"436904","totalValueInUsd":"5973.8","indian_port":"HYDERABAD AIR","hs_no":"29225090","bill_no":"8049632","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"78\/A,VENGALARAO NAGARHYDERABAD, ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE","year":"2021","qtr":"Q1","strtotime":1611340200,"product":"ACTIVE PHARMACEUTICAL INGREDIENT (2001261172&16.01.2021)DOMPERIDONE BP\/PH .EUR (MEIS GROUP B SL.NO : 1434)","address":"78\/A,VENGALARAO NAGARHYDERABAD","city":"ANDHRA PRADESH","supplier":"VASUDHA PHARMA CHEM","supplierCountry":"INDIA","foreign_port":"BOGOTA","customer":"TO THE ORDER OF","customerCountry":"COLOMBIA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"127.7","totalValueFC":"1293.3","currency":"USD","unitRateINR":9458.6149999999998,"date":"23-Jan-2021","totalValueINR":"94586.15","totalValueInUsd":"1293.3","indian_port":"HYDERABAD AIR","hs_no":"29225024","bill_no":"8111806","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"COLOMBIA","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"78\/A,VENGALARAO NAGARHYDERABAD, ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE","year":"2021","qtr":"Q1","strtotime":1611858600,"product":"ACTIVE PHARMACEUTICAL INGREDIENT 2001261 191 & 21.01.2021 DOMPERIDONE BP","address":"78\/A,VENGALARAO NAGARHYDERABAD","city":"ANDHRA PRADESH","supplier":"VASUDHA PHARMA CHEM","supplierCountry":"INDIA","foreign_port":"GUARULHOS","customer":"TO THE ORDER","customerCountry":"BRAZIL","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"107.1","totalValueFC":"1084.4","currency":"USD","unitRateINR":7931,"date":"29-Jan-2021","totalValueINR":"79310","totalValueInUsd":"1084.4","indian_port":"HYDERABAD AIR","hs_no":"29225024","bill_no":"8238298","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"78\/A,VENGALARAO NAGARHYDERABAD, ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE MALEATE","year":"2021","qtr":"Q1","strtotime":1611945000,"product":"DOMPERIDONE MALEATE BP (OTHER)","address":"101, SAI SIDDHI BLDG, PLOTNO.264 H, SECTOR-3, AIROLI,","city":"NAVI MUMBAI, M.S.","supplier":"ZEON PHARMA INDUSTRIES INDIA PVT LTD","supplierCountry":"INDIA","foreign_port":"CHITTAGONG","customer":"ISLAMI BANK BANGLAD","customerCountry":"BANGLADESH","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"38.5","totalValueFC":"11362.3","currency":"USD","unitRateINR":2770,"date":"30-Jan-2021","totalValueINR":"831000","totalValueInUsd":"11362.3","indian_port":"JNPT","hs_no":"29225090","bill_no":"8271466","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"101, SAI SIDDHI BLDG, PLOTNO.264 H, SECTOR-3, AIROLI,, NAVI MUMBAI, M.S.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"DOMPERIDONE","year":"2021","qtr":"Q1","strtotime":1612117800,"product":"PHARMACEUTICAL BULK DRUG DOMPERIDONE MAL EATE BP 2019 ( DTLS AS PER INV)","address":"247 & 248, UDYOG BHAVAN, SONAWALAROAD, GOREGAON EAST,","city":"MUMBAI. MAHARASHTRA","supplier":"AASTRID INTERNATIONAL PVT. LTD","supplierCountry":"INDIA","foreign_port":"HO CHI MINH CITY","customer":"TO THE ORDER OF,,,.,,,","customerCountry":"VIETNAM","quantity":"700.00","actualQuantity":"700","unit":"KGS","unitRateFc":"69.9","totalValueFC":"48400.6","currency":"USD","unitRateINR":5034.125,"date":"01-Feb-2021","totalValueINR":"3523887.5","totalValueInUsd":"48400.6","indian_port":"JNPT","hs_no":"29225024","bill_no":"8330624","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"VIETNAM, DEMOCRATIC REP. OF","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"247 & 248, UDYOG BHAVAN, SONAWALAROAD, GOREGAON EAST,, MUMBAI. 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    02-Jan-2021
    30-Aug-2024
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    Qatar.png
    USP/ BP Grade Domperidone (10 mg) Pellets needed in Qatar [ENA19757]
    A leading pharmaceutical company that focuses on the development & manufacturing of OSDs, intravenous solutions, eye drops, hemodialysis solutions, creams and lotions is looking for suppliers of USP/ BP Grade Domperidone (10 mg) Pellets for commercial purposes. The required quantity is 25 kg. The suppliers must support this enquiry with CoA.
    20 Jun 2024

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    20 Jun 2024

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    Reply Comment (27)

    20 Jun 2024

    india-flag.png
    Domperidone (20%) SR Pellets needed in India [ENA18443]
    A company that focuses on manufacturing of tablets, capsules, injections, syrups, drops, ointments & creams is looking for suppliers of Domperidone (20%) SR Pellets for commercial purposes. The required quantity is 50 kg. The suppliers must support this enquiry with CoA.
    25 Oct 2023

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    25 Oct 2023

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    Reply Comment (6)

    25 Oct 2023

    Mexico.png
    Domperidone (250 kg) API needed in Mexico [ENA17971]
    A company that focuses on research, development, manufacturing & marketing of various pharmaceutical products for the treatment of gastroenterology, gynecology, overweight and obesity is looking for suppliers of Domperidone (250 kg) API for commercial purposes. The suppliers must support this enquiry with CoA.
    07 Sep 2023

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    07 Sep 2023

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    07 Sep 2023

    Switzerland.png
    Various APIs needed in Switzerland [ENA16696]
    A leading research-based pharmaceutical company that focuses on the development & manufacturing of a broad range of finished formulations in immunology, infectiology, oncology, pulmonary hypertension and pain is looking for Various APIs for commercial purposes. The suppliers must support this enquiry with CEP or DMF. 1. Domperidone API 2. Flubendazole API 3. Mebendazole API 4. Cinnarizine API 5. Miconazole API 6. Miconazole Nitrate API 7. Loperamide API 8. Levocabastine API 9. Econazole Nitrate API 10. Ketoconazole API
    23 Mar 2023

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    23 Mar 2023

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    Reply Comment (19)

    23 Mar 2023

    india-flag.png
    Various APIs needed in India [ENA16230]
    A company that focuses on the development and manufacturing of nasal, eye & ear drops is looking for suppliers of Various APIs for development purposes. The required quantity is MOQ for each. The suppliers must support this enquiry with CoA. 1. IP/ BP/ USP Grade Pantoprazole API 2. IP/ BP/ USP Grade Domperidone API 3. BP Grade Flunarizine Dihydrochloride API 4. IP Grade Acetazolamide API 5. IP Grade Methylcobalamine API
    28 Jan 2023

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    28 Jan 2023

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    28 Jan 2023

    india-flag.png
    Various APIs needed in India [ENA16208]
    A company that focuses on the manufacturing of pellets is looking for suppliers of Various APIs for commercial purposes. The suppliers must support this enquiry with CoA. 1. Itraconazole (200 kg/ month) API 2. Pantoprazole (500 kg - 600 kg) API 3. Rabeprazole (500 kg - 600 kg) API 4. Esomeprazole (500 kg - 600 kg) API 5. Itopride (500 kg - 600 kg) API 6. Levosulpiride (500 kg - 600 kg) API 7. Domperidone (500 kg - 600 kg) API
    25 Jan 2023

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    25 Jan 2023

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    Reply Comment (8)

    25 Jan 2023

    india-flag.png
    IP Grade Domperidone (2 kg) API needed in India [ENA16037]
    A company that deals in various pharmaceutical products like injections, syrups & hygiene products is looking for suppliers of IP Grade Domperidone (2 kg) API for commercial purposes. The suppliers must support this enquiry with CoA.
    09 Jan 2023

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    09 Jan 2023

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    09 Jan 2023

    india-flag.png
    Various APIs needed in India [ENA15845]
    A contract research organization that focuses on the formulation development of conventional and novel drug delivery products is looking for suppliers of Various APIs for development purposes. The required quantity is MOQ for each. The suppliers must support this enquiry with CoA. 1. IP/ BP Grade Benfotiamine API 2. IP/ BP Grade Methylcobalamin API 3. IP/ BP Grade Gabapentin API 4. IP/ BP Grade Domperidone API 5. IP/ BP Grade Rabeprazole API
    16 Dec 2022

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    16 Dec 2022

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    Reply Comment (11)

    16 Dec 2022

    india-flag.png
    BP/ USP Grade Domperidone (MOQ) API needed in India [ENA15364]
    A pharmaceutical company that specializes in the development & manufacturing of oral formulations is looking for suppliers of BP/ USP Grade Domperidone (MOQ) API for commercial purpose. The suppliers must support this enquiry with CoA.
    19 Oct 2022

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    19 Oct 2022

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    19 Oct 2022

    VietNam.png
    Domperidone API needed in Vietnam [ENA14361]
    A company that deals in various pharmaceutical products is looking for suppliers of Domperidone API for commercial purpose. The suppliers must support this enquiry with CoA.
    15 Jul 2022

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    15 Jul 2022

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    15 Jul 2022

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    Domperidone Manufacturers | Traders | Suppliers

    Domperidone Manufacturers, Traders, Suppliers 1
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    We have 5 companies offering Domperidone

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    1. Aurobindo Pharma Limited
    2. Derivados Quimicos SAU
    3. Johnson & Johnson Innovative Medicine
    4. Sri Krishna Pharmaceuticals
    5. Vasudha Pharma Chem
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