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Chemistry

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Also known as: 4235-95-4, Dopc, Pc(18:1(9z)/18:1(9z)), 1,2-dioleoyl-l-alpha-lecithin, (r)-2,3-bis(oleoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate, 1,2-di-(9z-octadecenoyl)-sn-glycero-3-phosphocholine
Molecular Formula
C44H84NO8P
Molecular Weight
786.1  g/mol
InChI Key
SNKAWJBJQDLSFF-NVKMUCNASA-N
FDA UNII
H026DM5V6U

DOPC
PC(18:1(9Z)/18:1(9Z)) is a metabolite found in or produced by Saccharomyces cerevisiae.
1 2D Structure

DOPC

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl] 2-(trimethylazaniumyl)ethyl phosphate
2.1.2 InChI
InChI=1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,42H,6-19,24-41H2,1-5H3/b22-20-,23-21-/t42-/m1/s1
2.1.3 InChI Key
SNKAWJBJQDLSFF-NVKMUCNASA-N
2.1.4 Canonical SMILES
CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC
2.1.5 Isomeric SMILES
CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC
2.2 Other Identifiers
2.2.1 UNII
H026DM5V6U
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1,2-dioleoyl Glycerophosphocholine

2. 1,2-dioleoyl-sn-glycerol-3-ethylphosphocholine

3. 1,2-dioleoylglycerophosphocholine

4. 1,2-docpc

5. 1,2-oleoyl-sn-glycero-3-phosphocholine

6. 1,2-oleoylphosphatidylcholine

7. 1,2-oleoylphosphatidylcholine, (e,e)-isomer

8. 1,2-oleoylphosphatidylcholine, (l-alpha)-(r-(z,z))-isomer

9. 1,2-oleoylphosphatidylcholine, (r-(e,e))-isomer

10. 1,2-oleoylphosphatidylcholine, (z,z)-(+-)-isomer

11. 1,2-oleoylphosphatidylcholine, 14c-labeled, (r-(z,z))-isomer

12. Dielaidinoyl Lecithin

13. Dielaidoylphosphatidylcholine

14. Dioleoyl Lecithin

15. Dioleoyl Phosphatidylcholine

16. Dioleoylphosphatidylcholine

17. Dioleoylphosphatidylcholine, Dl-

18. Dioleylphosphatidylcholine

19. Dopc

2.3.2 Depositor-Supplied Synonyms

1. 4235-95-4

2. Dopc

3. Pc(18:1(9z)/18:1(9z))

4. 1,2-dioleoyl-l-alpha-lecithin

5. (r)-2,3-bis(oleoyloxy)propyl (2-(trimethylammonio)ethyl) Phosphate

6. 1,2-di-(9z-octadecenoyl)-sn-glycero-3-phosphocholine

7. H026dm5v6u

8. Pc(18:1/18:1)

9. (r)-2,3-bis(oleoyloxy)propyl [2-(trimethylammonio)ethyl] Phosphate

10. Choline Phosphate, 3-ester With L-1,2-diolein

11. (r-(z,z))-(7-oleoyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-enyl)trimethylammonium 4-oxide

12. Olein, 1,2-di-, L-, Dihydrogen Phosphate, Monoester With Choline Hydroxide

13. Pc 18:1

14. Pc 36:2

15. [(2r)-2,3-bis[[(z)-octadec-9-enoyl]oxy]propyl] 2-(trimethylazaniumyl)ethyl Phosphate

16. Choline, Hydroxide, Dihydrogen Phosphate, Inner Salt, Ester With L-1,2-diolein

17. Dioleoylphosphatidylcholine

18. Unii-h026dm5v6u

19. 1,2-dioleoyllec

20. Einecs 224-193-8

21. Mfcd00135191

22. Phosphatidylcholine 18:1

23. Dopc, L-

24. Dopc, R-

25. Schembl24888

26. 1,2-dioleoyl-sn-glycero-3-pc

27. Chebi:74669

28. Pdd 111

29. Dtxsid101274283

30. (z,z)-(1)-(7-oleoyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-enyl)trimethylammonium 4-oxide

31. Lmgp01010890

32. 1-oleoyl-2-oleoyl-phosphatidylcholine

33. Akos024418773

34. 1-18:1-2-18:1-phosphatidylcholine

35. Hy-113424a

36. Dioleoyl Phosphatidylcholine, L-

37. Dioleoyl Phosphatidylcholine, R-

38. As-72051

39. Bp-25710

40. 1,2-dioleoyl-rac-glycero-3-phosphocholine

41. 1, 2-dioleoyl-sn-glycero-3-phosphocholine

42. 1,2-dioleoyl-sn-glycero-3-phosphocho-line

43. Cs-0063306

44. D4250

45. 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine

46. 18:1-18:1-pc

47. 1-18:1-2-18:1-sn--glycerol-3-phosphocholine

48. A872903

49. Sn-glycerol-3-phosphocholine (1-18:1-2-18:1)

50. W-202732

51. 1,2-(9z-octadecenoyl)-sn--glycero-3-phosphocholine

52. Q27144815

53. 1,2-dioleoyl-sn-glycero-3-phosphocholine [ii]

54. 1-c18:1(omega-9)-2-c18:1(omega-9)-phosphatidylcholine

55. N,n,n-trimethyl 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

56. (r)-2,3-bis(oleoyloxy)propyl(2-(trimethylammonio)ethyl)phosphate

57. 1-(9z)-octadecenoyl-2-(9z)-octadecenoyl-sn-glycero-3-phosphocholine

58. (2-{[(2r)-2,3-bis[(9z)-octadec-9-enoyloxy]propyl Phosphonato]oxy}ethyl)trimethylazanium

59. (2r)-2,3-bis[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylazaniumyl)ethyl Phosphate

60. [(2s)-2,3-bis[[(z)-octadec-9-enoyl]oxy]propyl] 2-(trimethylazaniumyl)ethyl Phosphate

61. 18:1 (delta9-cis) Pc (dopc), 1,2-dioleoyl-sn-glycero-3-phosphocholine, Powder

62. (z,z)-4-hydroxy-n,n,n-trimethyl-10-oxo-7-[(1-oxo-9-octadecenyl)oxy]-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide Hydroxide Inner Salt

63. 3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium, 4-hydroxy-n,n,n-trimethyl-10-oxo-7-[(1-oxo-9-octadecenyl)oxy]-, Inner Salt, 4-oxide, [r-(z,z)]-

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 786.1 g/mol
Molecular Formula C44H84NO8P
XLogP313.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count42
Exact Mass785.59345564 g/mol
Monoisotopic Mass785.59345564 g/mol
Topological Polar Surface Area111 Ų
Heavy Atom Count54
Formal Charge0
Complexity972
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

DOPC Manufacturers

A DOPC manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of DOPC, including repackagers and relabelers. The FDA regulates DOPC manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. DOPC API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

DOPC Suppliers

A DOPC supplier is an individual or a company that provides DOPC active pharmaceutical ingredient (API) or DOPC finished formulations upon request. The DOPC suppliers may include DOPC API manufacturers, exporters, distributors and traders.

click here to find a list of DOPC suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

DOPC USDMF

A DOPC DMF (Drug Master File) is a document detailing the whole manufacturing process of DOPC active pharmaceutical ingredient (API) in detail. Different forms of DOPC DMFs exist exist since differing nations have different regulations, such as DOPC USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A DOPC DMF submitted to regulatory agencies in the US is known as a USDMF. DOPC USDMF includes data on DOPC's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The DOPC USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of DOPC suppliers with USDMF on PharmaCompass.

DOPC GMP

DOPC Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of DOPC GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right DOPC GMP manufacturer or DOPC GMP API supplier for your needs.

DOPC CoA

A DOPC CoA (Certificate of Analysis) is a formal document that attests to DOPC's compliance with DOPC specifications and serves as a tool for batch-level quality control.

DOPC CoA mostly includes findings from lab analyses of a specific batch. For each DOPC CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

DOPC may be tested according to a variety of international standards, such as European Pharmacopoeia (DOPC EP), DOPC JP (Japanese Pharmacopeia) and the US Pharmacopoeia (DOPC USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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