Find Draflazine manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

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JDMF

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EU WC

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NDC API

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API REF. PRICE (USD/KG)

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$ 0

MARKET PLACE

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API

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FDF

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Australia

Australia

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Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

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DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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US Medicaid

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0RELATED EXCIPIENT COMPANIES

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Chemistry

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Also known as: 120770-34-5, R-75231, (s)-draflazine, 1-[2-(4-amino-2,6-dichloroanilino)-2-oxoethyl]-4-[5,5-bis(4-fluorophenyl)pentyl]piperazine-2-carboxamide, R 75231, R75231
Molecular Formula
C30H33Cl2F2N5O2
Molecular Weight
604.5  g/mol
InChI Key
IWMYIWLIESDFRZ-UHFFFAOYSA-N
FDA UNII
0Y25DT968Y

Draflazine
1 2D Structure

Draflazine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[2-(4-amino-2,6-dichloroanilino)-2-oxoethyl]-4-[5,5-bis(4-fluorophenyl)pentyl]piperazine-2-carboxamide
2.1.2 InChI
InChI=1S/C30H33Cl2F2N5O2/c31-25-15-23(35)16-26(32)29(25)37-28(40)18-39-14-13-38(17-27(39)30(36)41)12-2-1-3-24(19-4-8-21(33)9-5-19)20-6-10-22(34)11-7-20/h4-11,15-16,24,27H,1-3,12-14,17-18,35H2,(H2,36,41)(H,37,40)
2.1.3 InChI Key
IWMYIWLIESDFRZ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CN(C(CN1CCCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)C(=O)N)CC(=O)NC4=C(C=C(C=C4Cl)N)Cl
2.2 Other Identifiers
2.2.1 UNII
0Y25DT968Y
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-aminocarbonyl-n-(4-amino-2,6-dichlorophenyl)-4-(5,5-bis(4-fluorophenyl)-pentyl)-1-piperazineacetamide

2. R 75 231

3. R 75231

4. R 88 016

5. R 88016

6. R-75231

7. R-88016

8. R75231

2.3.2 Depositor-Supplied Synonyms

1. 120770-34-5

2. R-75231

3. (s)-draflazine

4. 1-[2-(4-amino-2,6-dichloroanilino)-2-oxoethyl]-4-[5,5-bis(4-fluorophenyl)pentyl]piperazine-2-carboxamide

5. R 75231

6. R75231

7. 0y25dt968y

8. R-70380

9. Draflazinum

10. R70380

11. Draflazina

12. Draflazinum [inn-latin]

13. Draflazina [inn-spanish]

14. Draflazine [usan:inn:ban]

15. Unii-0y25dt968y

16. Draflazine [inn]

17. Draflazine (usan/inn)

18. Draflazine [usan]

19. (+-)-4'-amino-4-(5,5-bis(p-fluorophenyl)pentyl)-2-carbamoyl-2',6'-dichloro-1-piperazineacetanilide

20. 1-piperazineacetamide, 2-(aminocarbonyl)-n-(4-amino-2,6-dichlorophenyl)-4-(5,5-bis(4-fluorophenyl)pentyl)-

21. Schembl215826

22. Gtpl4590

23. Chembl1628717

24. Dtxsid60869655

25. Benzenemethanesulfonylchloride, 2-methyl-

26. 1-piperazineacetamide, 2-(aminocarbonyl)-n-(4-amino-2,6-dichlorophenyl)-4-(5,5-bis(4-fluorophenyl)pentyl)-,(+-)-

27. Db-057830

28. Hy-106841

29. Cs-0026695

30. Ft-0743995

31. D03906

32. Q27077112

33. (+/-)-2-(aminocarbonyl)-n-(4-amino-2,6-dichlorophenyl)-4-(5,5-bis(4-fluorophenyl)pentyl)-1-piperazine-acetamide

34. (+/-)-4'-amino-4-(5,5-bis(p-fluorophenyl)pentyl)-2-carbamoyl-2',6'-dichloro-1-piperazineacetanilide

35. 1-{[(4-amino-2,6-dichlorophenyl)carbamoyl]methyl}-4-[5,5-bis(4-fluorophenyl)pentyl]piperazine-2-carboxamide

36. 1-piperazineacetamide, 2-(aminocarbonyl)-n-(4-amino-2,6-dichlorophenyl)-4-(5,5-bis(4-fluorophenyl)pentyl)-, (+/-)-

37. 2-(aminocarbonyl)-n-(4-amino-2,6-dichlorophenyl)-4-(5,5-bis(4-fluorophenyl)pentyl)-1-piperazineacetamide

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 604.5 g/mol
Molecular Formula C30H33Cl2F2N5O2
XLogP35.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count11
Exact Mass603.1979370 g/mol
Monoisotopic Mass603.1979370 g/mol
Topological Polar Surface Area105 Ų
Heavy Atom Count41
Formal Charge0
Complexity810
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cardiotonic Agents

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)


Platelet Aggregation Inhibitors

Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. (See all compounds classified as Platelet Aggregation Inhibitors.)


ABOUT THIS PAGE

Looking for 120770-34-5 / Draflazine API manufacturers, exporters & distributors?

Draflazine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Draflazine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Draflazine manufacturer or Draflazine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Draflazine manufacturer or Draflazine supplier.

PharmaCompass also assists you with knowing the Draflazine API Price utilized in the formulation of products. Draflazine API Price is not always fixed or binding as the Draflazine Price is obtained through a variety of data sources. The Draflazine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Draflazine

Synonyms

120770-34-5, R-75231, (s)-draflazine, 1-[2-(4-amino-2,6-dichloroanilino)-2-oxoethyl]-4-[5,5-bis(4-fluorophenyl)pentyl]piperazine-2-carboxamide, R 75231, R75231

Cas Number

120770-34-5

Unique Ingredient Identifier (UNII)

0Y25DT968Y

Draflazine Manufacturers

A Draflazine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Draflazine, including repackagers and relabelers. The FDA regulates Draflazine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Draflazine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Draflazine Suppliers

A Draflazine supplier is an individual or a company that provides Draflazine active pharmaceutical ingredient (API) or Draflazine finished formulations upon request. The Draflazine suppliers may include Draflazine API manufacturers, exporters, distributors and traders.

click here to find a list of Draflazine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Draflazine USDMF

A Draflazine DMF (Drug Master File) is a document detailing the whole manufacturing process of Draflazine active pharmaceutical ingredient (API) in detail. Different forms of Draflazine DMFs exist exist since differing nations have different regulations, such as Draflazine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Draflazine DMF submitted to regulatory agencies in the US is known as a USDMF. Draflazine USDMF includes data on Draflazine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Draflazine USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Draflazine suppliers with USDMF on PharmaCompass.

Draflazine GMP

Draflazine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Draflazine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Draflazine GMP manufacturer or Draflazine GMP API supplier for your needs.

Draflazine CoA

A Draflazine CoA (Certificate of Analysis) is a formal document that attests to Draflazine's compliance with Draflazine specifications and serves as a tool for batch-level quality control.

Draflazine CoA mostly includes findings from lab analyses of a specific batch. For each Draflazine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Draflazine may be tested according to a variety of international standards, such as European Pharmacopoeia (Draflazine EP), Draflazine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Draflazine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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