Find Dromostanolone Propionate manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Dromostanolone propionate, 521-12-0, Permastril, Emdisterone, Masterid, Masteron
Molecular Formula
C23H36O3
Molecular Weight
360.5  g/mol
InChI Key
NOTIQUSPUUHHEH-UXOVVSIBSA-N
FDA UNII
X20UZ57G4O

Dromostanolone Propionate
Dromostanolone Propionate is the propionate salt form of dromostanolone, a synthetic anabolic steroid related to dihydrotestosterone that has antiestrogenic effects. Dromostanolone inhibits the growth of estrogen receptor-presenting breast cancers; its virilizing effects limit its clinical usefulness. (NCI)
1 2D Structure

Dromostanolone Propionate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(2R,5S,8R,9S,10S,13S,14S,17S)-2,10,13-trimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] propanoate
2.1.2 InChI
InChI=1S/C23H36O3/c1-5-21(25)26-20-9-8-17-16-7-6-15-12-19(24)14(2)13-23(15,4)18(16)10-11-22(17,20)3/h14-18,20H,5-13H2,1-4H3/t14-,15+,16+,17+,18+,20+,22+,23+/m1/s1
2.1.3 InChI Key
NOTIQUSPUUHHEH-UXOVVSIBSA-N
2.1.4 Canonical SMILES
CCC(=O)OC1CCC2C1(CCC3C2CCC4C3(CC(C(=O)C4)C)C)C
2.1.5 Isomeric SMILES
CCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C@H](C(=O)C4)C)C)C
2.2 Other Identifiers
2.2.1 UNII
X20UZ57G4O
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2 Alpha-methyldihydrotestosterone Propionate

2. Drolban

3. Dromostanolone Propionate

4. Masteril

5. Masterone

6. Nsc 12198

7. Nsc-12198

2.3.2 Depositor-Supplied Synonyms

1. Dromostanolone Propionate

2. 521-12-0

3. Permastril

4. Emdisterone

5. Masterid

6. Masteron

7. Blackburn Compound

8. Drolban

9. 2mdtp

10. 2m-dhtp

11. Masteril

12. Masterone

13. Medrotestron Propionate

14. Medrotestrone Propanoate

15. Medrotestrone Propionate

16. Mdht

17. Dromostanolone Proprionate

18. Lilly 32379

19. Re 346

20. Nsc-1298

21. Dromostanolone 17-propionate

22. Rs 1567

23. 2alpha-methyl-4,5-dihydrotestosterone Propionate

24. Testosterone, 4,5alpha-dihydro-2alpha-methyl-, Propionate

25. Nsc-12198

26. 17beta-hydroxy-2alpha-methyl-5alpha-androstan-3-one Propionate

27. X20uz57g4o

28. Chebi:31523

29. Dromostanolone Propionate [usan]

30. [(2r,5s,8r,9s,10s,13s,14s,17s)-2,10,13-trimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] Propanoate

31. Androstan-3-one, 2-methyl-17-(1-oxopropoxy)-, (2a,5a,17b)-

32. 2.alpha.-methyldihydrotestosterone Propionate

33. 17.beta.-hydroxy-2.alpha.-methyl-5.alpha.-androstan-3-one Propionate

34. 2.alpha.-methyl-4,5-dihydrotestosterone Propionate

35. Drostanolone Propionate (jan)

36. 2alpha-methyl-3-oxo-5alpha-androstan-17beta-yl Propanoate

37. Dromostanolone Propionate (usan)

38. Nomasteron

39. Drostanolone Propionate [jan]

40. (2r,5s,8r,9s,10s,13s,14s,17s)-2,10,13-trimethyl-3-oxohexadecahydro-1h-cyclopenta[a]phenanthren-17-yl Propionate

41. Drolban (tn)

42. Unii-x20uz57g4o

43. Masteron (tn)

44. Einecs 208-303-1

45. Dromostanolone Propionate [usan:usp]

46. Brn 3161958

47. Ai3-52810

48. Schembl3173

49. Androstan-3-one, 2-methyl-17-(1-oxopropoxy)-

50. 4-08-00-00654 (beilstein Handbook Reference)

51. 17b-hydroxy-2a-methyl-5a-androstan-3-one Propionate

52. Gtpl6947

53. Chembl1201048

54. Dtxsid1022972

55. Androstan-3-one, 2-methyl-17-(1-oxopropoxy)-, (2.alpha.,5.alpha.,17.beta.)-

56. (2alpha,5alpha,17beta)-2-methyl-3-oxoandrostan-17-yl Propanoate

57. Nsc12198

58. Zinc4213057

59. Mfcd01669961

60. S4794

61. Dromostanolone Propionate [mi]

62. Akos015895157

63. Ccg-268166

64. Db14655

65. Drostanolone Propionate [mart.]

66. Ds-3972

67. Drostanolone Propionate [who-dd]

68. Ncgc00507798-01

69. Hy-107344

70. Cs-0028187

71. C15917

72. D01534

73. Dromostanolone Propionate [orange Book]

74. 521d120

75. A828929

76. Q5308606

77. W-105852

78. Drostanolone Propionate 100 Microg/ml In Acetonitrile

79. Testosterone,5.alpha.-dihydro-2.alpha.-methyl-, Propionate

80. Testosterone, 4,5.alpha.-dihydro-2.alpha.-methyl-, Propionate

81. Androstan-3-one,2-methyl-17-(1-oxopropoxy)-,(2

82. A,5

83. A,17

84. A)-

85. 5-alpha-androstan-3-one, 17-beta-hydroxy-2-alpha-methyl-, Propionate

86. 5.alpha.-androstan-3-one, 17.beta.-hydroxy-2.alpha.-methyl-, Propionate

87. Androstan-3-one, 2-methyl-17-(1-oxopropoxy)-, (2alpha,5alpha,17beta)-

88. 2-methyl-3-oxoandrostan-17-yl Propionate, (2.alpha.,5.alpha.,17.beta.)- #

89. Androstan-3-one, 2-methyl-17-(1-oxopropoxy)-, (2.alpha.,5.alpha.,17.beta

90. [(2r,5s,8r,9s,10s,13s,14s,17s)-2,10,13-trimethyl-3-oxidanylidene-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] Propanoate

91. Propanoic Acid [(2r,5s,8r,9s,10s,13s,14s,17s)-2,10,13-trimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] Ester

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 360.5 g/mol
Molecular Formula C23H36O3
XLogP35.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass360.26644501 g/mol
Monoisotopic Mass360.26644501 g/mol
Topological Polar Surface Area43.4 Ų
Heavy Atom Count26
Formal Charge0
Complexity598
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

For use in females, for palliation of androgenresponsive recurrent mammary cancer in women who are more than one year but less than five years postmenopausal.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Dromostanolone is a synthetic androgen, or male hormone, similar to testosterone. Dromostanolone works by attaching itself to androgen receptors; this causes it to interact with the parts of the cell involved in the making of proteins. It may cause an increase in the synthesis of some proteins or a decrease in the synthesis of others. These proteins have a variety of effects, including blocking the growth of some types of breast cancer cells, stimulating cells that cause male sexual characteristics, and stimulating the production of red blood cells.


5.2 Absorption, Distribution and Excretion

Absorption

Well absorbed following parenteral administration.


5.3 Mechanism of Action

Dromostanolone is a synthetic androgenic anabolic steroid and is approximately 5 times as potent as natural methyltestosterone. Like testosterone and other androgenic hormones, dromostanolone binds to the androgen receptor. This causes downstream genetic transcriptional changes. This ultimately causes retention of nitrogen, potassium, and phosphorus; increases protein anabolism; and decreases amino acid catabolism. The antitumour activity of dromostanolone appears related to reduction or competitive inhibition of prolactin receptors or estrogen receptors or production.


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Looking for 521-12-0 / Dromostanolone Propionate API manufacturers, exporters & distributors?

Dromostanolone Propionate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Dromostanolone Propionate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Dromostanolone Propionate manufacturer or Dromostanolone Propionate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Dromostanolone Propionate manufacturer or Dromostanolone Propionate supplier.

PharmaCompass also assists you with knowing the Dromostanolone Propionate API Price utilized in the formulation of products. Dromostanolone Propionate API Price is not always fixed or binding as the Dromostanolone Propionate Price is obtained through a variety of data sources. The Dromostanolone Propionate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Dromostanolone Propionate

Synonyms

521-12-0, Permastril, Emdisterone, Masterid, Masteron, Blackburn compound

Cas Number

521-12-0

Unique Ingredient Identifier (UNII)

X20UZ57G4O

About Dromostanolone Propionate

Dromostanolone Propionate is the propionate salt form of dromostanolone, a synthetic anabolic steroid related to dihydrotestosterone that has antiestrogenic effects. Dromostanolone inhibits the growth of estrogen receptor-presenting breast cancers; its virilizing effects limit its clinical usefulness. (NCI)

Dromostanolone Propionate Manufacturers

A Dromostanolone Propionate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Dromostanolone Propionate, including repackagers and relabelers. The FDA regulates Dromostanolone Propionate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Dromostanolone Propionate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Dromostanolone Propionate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Dromostanolone Propionate Suppliers

A Dromostanolone Propionate supplier is an individual or a company that provides Dromostanolone Propionate active pharmaceutical ingredient (API) or Dromostanolone Propionate finished formulations upon request. The Dromostanolone Propionate suppliers may include Dromostanolone Propionate API manufacturers, exporters, distributors and traders.

click here to find a list of Dromostanolone Propionate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Dromostanolone Propionate USDMF

A Dromostanolone Propionate DMF (Drug Master File) is a document detailing the whole manufacturing process of Dromostanolone Propionate active pharmaceutical ingredient (API) in detail. Different forms of Dromostanolone Propionate DMFs exist exist since differing nations have different regulations, such as Dromostanolone Propionate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Dromostanolone Propionate DMF submitted to regulatory agencies in the US is known as a USDMF. Dromostanolone Propionate USDMF includes data on Dromostanolone Propionate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Dromostanolone Propionate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Dromostanolone Propionate suppliers with USDMF on PharmaCompass.

Dromostanolone Propionate GMP

Dromostanolone Propionate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Dromostanolone Propionate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Dromostanolone Propionate GMP manufacturer or Dromostanolone Propionate GMP API supplier for your needs.

Dromostanolone Propionate CoA

A Dromostanolone Propionate CoA (Certificate of Analysis) is a formal document that attests to Dromostanolone Propionate's compliance with Dromostanolone Propionate specifications and serves as a tool for batch-level quality control.

Dromostanolone Propionate CoA mostly includes findings from lab analyses of a specific batch. For each Dromostanolone Propionate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Dromostanolone Propionate may be tested according to a variety of international standards, such as European Pharmacopoeia (Dromostanolone Propionate EP), Dromostanolone Propionate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Dromostanolone Propionate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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