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    ACTIVE PHARMA INGREDIENTS

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    Synopsis

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    Chemistry

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    Also known as:
    Molecular Formula
    C17H20N4S
    Molecular Weight
    312.4  g/mol
    InChI Key
    WXPNDRBBWZMPQG-UHFFFAOYSA-N
    Olanzapine
    1 2D Structure

    Olanzapine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine
    2.1.2 InChI
    InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3
    2.1.3 InChI Key
    WXPNDRBBWZMPQG-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=CC2=C(NC3=CC=CC=C3N=C2S1)N4CCN(CC4)C
    2.1.5 Isomeric SMILES
    CC1=CC2=C(NC3=CC=CC=C3N=C2S1)N4CCN(CC4)C
    2.2 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 312.4 g/mol
    Molecular Formula C17H20N4S
    XLogP32.8
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count1
    Exact Mass312.14086783 g/mol
    Monoisotopic Mass312.14086783 g/mol
    Topological Polar Surface Area56.2 A^2
    Heavy Atom Count22
    Formal Charge0
    Complexity543
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 8  
    Drug NameOlanzapine
    PubMed HealthOlanzapine
    Drug ClassesAntipsychotic
    Drug LabelOlanzapine is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresponds to a...
    Active IngredientOlanzapine
    Dosage FormTablet; Injectable; Tablet, orally disintegrating
    Routeoral; Oral; Intramuscular
    Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
    Market StatusTentative Approval; Prescription
    CompanyMylan Pharms; Apotex; Aurobindo Pharma; Sun Pharm Inds; Torrent Pharms; Barr Labs; Sandoz; Par Pharm; Roxane; Teva Pharms; Macleods Pharms; Jubilant Generics; Luitpold; Dr Reddys Labs; Orchid Hlthcare; Mylan

    2 of 8  
    Drug NameSymbyax
    PubMed HealthOlanzapine/Fluoxetine (By mouth)
    Drug ClassesAntidepressant, Antipsychotic
    Active IngredientFluoxetine hydrochloride; olanzapine
    Dosage FormCapsule
    RouteOral
    Strengtheq 50mg base; eq 6mg base; eq 12mg base; eq 3mg base; eq 25mg base
    Market StatusPrescription
    CompanyLilly

    3 of 8  
    Drug NameZyprexa
    Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
    Active IngredientOlanzapine
    Dosage FormTablet; Injectable
    RouteOral; Intramuscular
    Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
    Market StatusPrescription
    CompanyLilly

    4 of 8  
    Drug NameZyprexa zydis
    Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
    Active IngredientOlanzapine
    Dosage FormTablet, orally disintegrating
    RouteOral
    Strength15mg; 5mg; 10mg; 20mg
    Market StatusPrescription
    CompanyLilly

    5 of 8  
    Drug NameOlanzapine
    PubMed HealthOlanzapine
    Drug ClassesAntipsychotic
    Drug LabelOlanzapine is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresponds to a...
    Active IngredientOlanzapine
    Dosage FormTablet; Injectable; Tablet, orally disintegrating
    Routeoral; Oral; Intramuscular
    Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
    Market StatusTentative Approval; Prescription
    CompanyMylan Pharms; Apotex; Aurobindo Pharma; Sun Pharm Inds; Torrent Pharms; Barr Labs; Sandoz; Par Pharm; Roxane; Teva Pharms; Macleods Pharms; Jubilant Generics; Luitpold; Dr Reddys Labs; Orchid Hlthcare; Mylan

    6 of 8  
    Drug NameSymbyax
    PubMed HealthOlanzapine/Fluoxetine (By mouth)
    Drug ClassesAntidepressant, Antipsychotic
    Active IngredientFluoxetine hydrochloride; olanzapine
    Dosage FormCapsule
    RouteOral
    Strengtheq 50mg base; eq 6mg base; eq 12mg base; eq 3mg base; eq 25mg base
    Market StatusPrescription
    CompanyLilly

    7 of 8  
    Drug NameZyprexa
    Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
    Active IngredientOlanzapine
    Dosage FormTablet; Injectable
    RouteOral; Intramuscular
    Strength2.5mg; 10mg/vial; 7.5mg; 15mg; 5mg; 10mg; 20mg
    Market StatusPrescription
    CompanyLilly

    8 of 8  
    Drug NameZyprexa zydis
    Drug LabelZYPREXA (olanzapine) is an atypical antipsychotic that belongs to the thienobenzodiazepine class. The chemical designation is 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b] [1,5]benzodiazepine. The molecular formula is C17H20N4S, which corresp...
    Active IngredientOlanzapine
    Dosage FormTablet, orally disintegrating
    RouteOral
    Strength15mg; 5mg; 10mg; 20mg
    Market StatusPrescription
    CompanyLilly

    API Reference Price

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1) -PH EUR, MFG DT:JA N- 2024, RETEST DT:DEC-2024, BATCH NO: OZ P2401004.S\/B#78","address":"PLOT NO.1-A SEC-16A","city":"NOIDA (U.P) INDIA","supplier":"SANOFI","supplierCountry":"INDIA","foreign_port":"DUBAI","customer":"JUBILANT PHARMOVA","customerCountry":"INDIA","quantity":"17.90","actualQuantity":"17.9","unit":"KGS","unitRateFc":"1030","totalValueFC":"18649.5","currency":"USD","unitRateINR":"86520","date":"28-Mar-2024","totalValueINR":"1548708","totalValueInUsd":"18649.5","indian_port":"Bangalore Air","hs_no":"29349990","bill_no":"2789201","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"DUBAI","supplierAddress":"ESENTEPE MAH. BUYUKDERE CAD, 193 APT NO:193\/14 SISLI ISTANBUL Istanbul, , Turkey Turkey","customerAddress":"PLOT NO.1-A SEC-16A"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715106600,"product":"OLANZAPINE","address":"SHANKAR TOWERS PLOT NO. A30,A.I.E","city":"HYDERABAD,TELANGANA","supplier":"ZHEJIANG SUPOR PHARMACEUTICALS CO., LTD","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"ANTHEA PHARMA PVT LTD","customerCountry":"INDIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"20000","totalValueFC":"60944.6","currency":"USD","unitRateINR":"1687000","date":"08-May-2024","totalValueINR":"5061000","totalValueInUsd":"60944.6","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"3386822","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"LTD. YUEDONG ROAD,PAOJIANG INDUSTRIAL ZONE,SHAOXING, ZHEJIANG 312071 CHINA","customerAddress":"SHANKAR TOWERS PLOT NO. A30,A.I.E"}]
    05-Jan-2021
    29-Aug-2024
    KGS
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - TABLET;ORAL - 10MG

    USFDA APPLICATION NUMBER - 20592

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    DOSAGE - TABLET;ORAL - 15MG

    USFDA APPLICATION NUMBER - 20592

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    DOSAGE - TABLET;ORAL - 2.5MG

    USFDA APPLICATION NUMBER - 20592

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    DOSAGE - TABLET;ORAL - 20MG

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    DOSAGE - TABLET;ORAL - 5MG

    USFDA APPLICATION NUMBER - 20592

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    DOSAGE - TABLET;ORAL - 7.5MG

    USFDA APPLICATION NUMBER - 20592

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    DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL -...DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL - 10MG

    USFDA APPLICATION NUMBER - 21086

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    DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL -...DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL - 15MG

    USFDA APPLICATION NUMBER - 21086

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    DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL -...DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL - 20MG

    USFDA APPLICATION NUMBER - 21086

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    DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL -...DOSAGE - TABLET, ORALLY DISINTEGRATING;ORAL - 5MG

    USFDA APPLICATION NUMBER - 21086

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