Find DTXSID50185290 manufacturers, exporters & distributors on PharmaCompass

DTXSID50185290

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 EU WC

1 API Suppliers
1 EU WC

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Hs2s9vk3nh, 313640-86-7, Unii-hs2s9vk3nh, Dtxsid50185290, Q27280070, 1h-benzimidazole, 2-((r)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-, hydrate (2:3)

Molecular Formula

C₃₂H₃₄F₆N₆O₇S₂

Molecular Weight

792.8 g/mol

InChI Key

XTQWZVSRVXCIGB-BBBDYAHLSA-N

FDA UNII

HS2S9VK3NH

The R-isomer of lansoprazole that is used to treat severe GASTROESOPHAGEAL REFLUX DISEASE.

1 2D Structure

DTXSID50185290

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole;trihydrate

2.1.2 InChI

InChI=1S/2C16H14F3N3O2S.3H2O/c2*1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15;;;/h2*2-7H,8-9H2,1H3,(H,21,22);3*1H2/t2*25-;;;/m11.../s1

2.1.3 InChI Key

XTQWZVSRVXCIGB-BBBDYAHLSA-N

2.1.4 Canonical SMILES

CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F.CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F.O.O.O

2.1.5 Isomeric SMILES

CC1=C(C=CN=C1C[S@@](=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F.CC1=C(C=CN=C1C[S@@](=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F.O.O.O

2.2 Other Identifiers

2.2.1 UNII

HS2S9VK3NH

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2-((r)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1h-benzimidazole

2. Dexilant

3. Dexlansoprazole

4. Lansoprazole, R Isomer

5. Lansoprazole, R-isomer

6. R Lansoprazole

7. R-isomer Lansoprazole

8. R-lansoprazole

9. T 168390

10. T-168390

11. T168390

12. Tak 390

13. Tak 390mr

14. Tak-390

15. Tak-390mr

16. Tak390

17. Tak390mr

2.3.2 Depositor-Supplied Synonyms

1. Hs2s9vk3nh

2. 313640-86-7

3. Unii-hs2s9vk3nh

4. Dtxsid50185290

5. Q27280070

6. 1h-benzimidazole, 2-((r)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-, Hydrate (2:3)

2.4 Create Date

2013-07-08

3 Chemical and Physical Properties

Molecular Formula	C₃₂H₃₄F₆N₆O₇S₂
Molecular Weight	792.8 g/mol
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	19
Rotatable Bond Count	10
Exact Mass	792.18345876 g/mol
Monoisotopic Mass	792.18345876 g/mol
Topological Polar Surface Area	177 Å²
Heavy Atom Count	53
Formal Charge	0
Complexity	480
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	5

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Ulcer Agents

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief. (See all compounds classified as Anti-Ulcer Agents.)

Proton Pump Inhibitors

Compounds that inhibit H(+)-K(+)-EXCHANGING ATPASE. They are used as ANTI-ULCER AGENTS and sometimes in place of HISTAMINE H2 ANTAGONISTS for GASTROESOPHAGEAL REFLUX. (See all compounds classified as Proton Pump Inhibitors.)

API SUPPLIERS