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    Chemistry

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    Also known as: Mls001401438, Chembl1895091, Hms2051p14, Hms2233m10, Ccg-101038, Nc00288
    Molecular Formula
    C23H30N2O9
    Molecular Weight
    478.5  g/mol
    InChI Key
    AXAGNMKWGBWLMO-GQMFVQBYSA-N
    Formoterol Fumarate
    1 2D Structure

    Formoterol Fumarate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (E)-but-2-enedioic acid;N-[2-hydroxy-5-[(1S)-1-hydroxy-2-[[(2S)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide;hydrate
    2.1.2 InChI
    InChI=1S/C19H24N2O4.C4H4O4.H2O/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22;5-3(6)1-2-4(7)8;/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22);1-2H,(H,5,6)(H,7,8);1H2/b;2-1+;/t13-,19+;;/m0../s1
    2.1.3 InChI Key
    AXAGNMKWGBWLMO-GQMFVQBYSA-N
    2.1.4 Canonical SMILES
    CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O.C(=CC(=O)O)C(=O)O.O
    2.1.5 Isomeric SMILES
    C[C@@H](CC1=CC=C(C=C1)OC)NC[C@H](C2=CC(=C(C=C2)O)NC=O)O.C(=C/C(=O)O)\C(=O)O.O
    2.2 Synonyms
    2.2.1 Depositor-Supplied Synonyms

    1. Mls001401438

    2. Chembl1895091

    3. Hms2051p14

    4. Hms2233m10

    5. Ccg-101038

    6. Nc00288

    7. Smr000471620

    2.3 Create Date
    2007-12-08
    3 Chemical and Physical Properties
    Molecular Weight 478.5 g/mol
    Molecular Formula C23H30N2O9
    Hydrogen Bond Donor Count7
    Hydrogen Bond Acceptor Count10
    Rotatable Bond Count10
    Exact Mass478.19513054 g/mol
    Monoisotopic Mass478.19513054 g/mol
    Topological Polar Surface Area166 Ų
    Heavy Atom Count34
    Formal Charge0
    Complexity507
    Isotope Atom Count0
    Defined Atom Stereocenter Count2
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count1
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3

    API Reference Price

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ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"XXKE XXA","supplierCountry":"SPAIN","foreign_port":"BARCELONA","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"135000","totalValueFC":"136574.5","currency":"USD","unitRateINR":"11367000","date":"23-Oct-2023","totalValueINR":"11367000","totalValueInUsd":"136574.5","indian_port":"Indore-EPZ\/SEZ","hs_no":"29420090","bill_no":"1006964","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"BARCELONA","supplierAddress":"N\/A","customerAddress":"159, C.S.T. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1698690600,"product":"FORMOTEROL FUMARATE","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"CHEMO IBERICA, S.A.","supplierCountry":"ITALY","foreign_port":"N\/A","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"0.05","actualQuantity":"50","unit":"GMS","unitRateFc":"150","totalValueFC":"7587.5","currency":"USD","unitRateINR":"12630","date":"31-Oct-2023","totalValueINR":"631500","totalValueInUsd":"7587.5","indian_port":"Vizag-EPZ\/SEZ","hs_no":"29093090","bill_no":"1002009","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"MANUEL POMBO ANGULO, 3RD FLOOR 28050 MADRID, SPAIN","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1700677800,"product":"FORMOTEROL FUMARATE DIHYDRATE","address":"882\/1-871, NEAR KANKAVATI ,VILLAGE-","city":"AHMEDABAD, GUJARAT","supplier":"AMNEAL PHARMACEUTICALS","supplierCountry":"IRELAND","foreign_port":"DUBLIN","customer":"AMNEAL PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"10","unit":"GMS","unitRateFc":"219","totalValueFC":"2211.8","currency":"USD","unitRateINR":"18417.9","date":"23-Nov-2023","totalValueINR":"184179","totalValueInUsd":"2211.8","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29242990","bill_no":"1004738","productDescription":"API","marketType":"REGULATED MARKET","country":"IRELAND","selfForZScoreResived":"Pharma Grade","supplierPort":"DUBLIN","supplierAddress":"CAHIR ROAD,CASHEL, CO TIPPERARY,E25XD51, , IRELAND","customerAddress":"882\/1-871, NEAR KANKAVATI ,VILLAGE-"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1702578600,"product":"FORMOTEROL FUMARATE","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"INKE S.A","supplierCountry":"SPAIN","foreign_port":"BARCELONA","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"135068.9","totalValueFC":"136783.7","currency":"USD","unitRateINR":"11386304","date":"15-Dec-2023","totalValueINR":"11386304","totalValueInUsd":"136783.7","indian_port":"Indore-EPZ\/SEZ","hs_no":"29242970","bill_no":"1008145","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"BARCELONA","supplierAddress":"AREA INDUSTRIAL DEL LLOBREGATC\/ARGENT 1 08755 CASTELLBISBA BARCELONA, SPAIN SPAIN","customerAddress":"159, C.S.T. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1707849000,"product":"FORMOTEROL FUMARATE","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"INKE S.A","supplierCountry":"SPAIN","foreign_port":"BARCELONA","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"134759.2","totalValueFC":"136588.3","currency":"USD","unitRateINR":"11333250","date":"14-Feb-2024","totalValueINR":"11333250","totalValueInUsd":"136588.3","indian_port":"Indore-EPZ\/SEZ","hs_no":"29420090","bill_no":"1001005","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"BARCELONA","supplierAddress":"N\/A","customerAddress":"159, C.S.T. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715193000,"product":"FORMOTEROL FUMARATE (IUPAC NAME:N-(2-HYDROXY-5-(1-HYDROXY-2-((1-(4-METHOXYPHENYL)PROPAN-2-YL)AMINO)ETHYL)PHENYL)FORMAMID","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"INKE S.A","supplierCountry":"SPAIN","foreign_port":"BARCELONA","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"135000","totalValueFC":"136612.8","currency":"USD","unitRateINR":"11387250","date":"09-May-2024","totalValueINR":"11387250","totalValueInUsd":"136612.8","indian_port":"Indore-EPZ\/SEZ","hs_no":"29420090","bill_no":"1003275","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"BARCELONA","supplierAddress":"N\/A","customerAddress":"159, C.S.T. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717525800,"product":"FORMOTEROL FUMARATE (BATCH NO.P-126M) (15 GMS) FORMOTEROL FUMARATE DIHYDRATE","address":"B\/2 MAHALAXMI CHAMBERS","city":"MUMBAI. MAHARASHTRA","supplier":"INKE S.A","supplierCountry":"SPAIN","foreign_port":"BARCELONA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.02","actualQuantity":"0.015","unit":"KGS","unitRateFc":"176000","totalValueFC":"2925.3","currency":"EUR","unitRateINR":"16280000","date":"05-Jun-2024","totalValueINR":"244200","totalValueInUsd":"2925.3","indian_port":"Bombay Air","hs_no":"29349990","bill_no":"3844348","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"BARCELONA","supplierAddress":"AREA INDUSTRIAL DEL LIOBREGAT C\/ARGENT, 1 08755 CASTELBISBAL BARCELONASPAIN Barcelona, , Spain Spain","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717612200,"product":"FORMOTEROL FUMARATE (IUPAC NAME:N-(2-HYDROXY-5-(1-HYDROXY-2-((1-(4-METHOXYPHENYL)PROPAN-2-YL)AMINO)ETHYL)PHENYL)FORMAMID","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"INKE S.A","supplierCountry":"SPAIN","foreign_port":"BARCELONA","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"135000","totalValueFC":"272815.7","currency":"USD","unitRateINR":"11387250","date":"06-Jun-2024","totalValueINR":"22774500","totalValueInUsd":"272815.7","indian_port":"Indore-EPZ\/SEZ","hs_no":"29420090","bill_no":"1004048","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"BARCELONA","supplierAddress":"N\/A","customerAddress":"159, C.S.T. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722191400,"product":"FORMOTEROL FUMARATE (IUPAC NAME N-(2-HYDROXY-5-(1-HYDROXY-2-((1-(4-METHOXYPHENYL)PROPAN-2-YL)AMINO)ETHYL)PHENYL)FORMAMID","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"INKE S.A","supplierCountry":"SPAIN","foreign_port":"BARCELONA","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"135000","totalValueFC":"273097.3","currency":"USD","unitRateINR":"11414250","date":"29-Jul-2024","totalValueINR":"22828500","totalValueInUsd":"273097.3","indian_port":"Indore-EPZ\/SEZ","hs_no":"29420090","bill_no":"1005513","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"BARCELONA","supplierAddress":"N\/A","customerAddress":"159, C.S.T. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722364200,"product":"FORMOTEROL FUMARATE","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"XXKE XXA","supplierCountry":"SPAIN","foreign_port":"BARCELONA","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"0.27","actualQuantity":"266","unit":"GMS","unitRateFc":"148","totalValueFC":"39823.1","currency":"USD","unitRateINR":"12514.5","date":"31-Jul-2024","totalValueINR":"3328857","totalValueInUsd":"39823.1","indian_port":"Indore-EPZ\/SEZ","hs_no":"29242990","bill_no":"1005578","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"BARCELONA","supplierAddress":"N\/A","customerAddress":"159, C.S.T. ROAD,"}]
    04-Jan-2021
    19-Sep-2024
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - POWDER;INHALATION - 0.012MG/INH **Fe...DOSAGE - POWDER;INHALATION - 0.012MG/INH **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 20831

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    DOSAGE - POWDER, METERED;INHALATION - 0.4MG/I...DOSAGE - POWDER, METERED;INHALATION - 0.4MG/INH;0.012MG/INH

    USFDA APPLICATION NUMBER - 210595

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.08MG...DOSAGE - AEROSOL, METERED;INHALATION - 0.08MG/INH;0.0045MG/INH

    USFDA APPLICATION NUMBER - 21929

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.16MG...DOSAGE - AEROSOL, METERED;INHALATION - 0.16MG/INH;0.0045MG/INH

    USFDA APPLICATION NUMBER - 21929

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.005M...DOSAGE - AEROSOL, METERED;INHALATION - 0.005MG/INH;0.05MG/INH

    USFDA APPLICATION NUMBER - 22518

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.005M...DOSAGE - AEROSOL, METERED;INHALATION - 0.005MG/INH;0.1MG/INH

    USFDA APPLICATION NUMBER - 22518

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.005M...DOSAGE - AEROSOL, METERED;INHALATION - 0.005MG/INH;0.2MG/INH

    USFDA APPLICATION NUMBER - 22518

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    01

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    Patent Expiration Date : 2031-03-17

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    US Patent Number : 8815258

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    Application Number : 212122

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    Patent Expiration Date : 2031-03-17

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    Patent Expiration Date : 2029-04-07

    BUDESONIDE; FORMOTEROL FUMARATE DIHYDRATE

    US Patent Number : 8616196

    Drug Substance Claim :

    Drug Product Claim : Y

    Application Number : 21929

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    Patent Expiration Date : 2029-04-07

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    Patent Expiration Date : 2038-10-05

    BUDESONIDE; FORMOTEROL FUMARATE; GLYCOPYRROLATE

    US Patent Number : 11331442

    Drug Substance Claim :

    Drug Product Claim : Y

    Application Number : 212122

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    Patent Expiration Date : 2038-10-05

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    Patent Expiration Date : 2026-04-10

    BUDESONIDE; FORMOTEROL FUMARATE DIHYDRATE

    US Patent Number : 7587988

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    Application Number : 21929

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    Patent Expiration Date : 2026-04-10

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    ASTRAZENECA

    United Kingdom
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    Patent Expiration Date : 2029-04-16

    BUDESONIDE; FORMOTEROL FUMARATE DIHYDRATE

    US Patent Number : 8528545*PED

    Drug Substance Claim :

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    Application Number : 21929

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    Patent Expiration Date : 2029-04-16

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    ASTRAZENECA

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    ASTRAZENECA

    United Kingdom
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    Patent Expiration Date : 2031-03-17

    FORMOTEROL FUMARATE; GLYCOPYRROLATE

    US Patent Number : 8815258

    Drug Substance Claim :

    Drug Product Claim :

    Application Number : 208294

    Patent Use Code : U-2889

    Delist Requested :

    Patent Use Description :

    Patent Expiration Date : 2031-03-17

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    ASTRAZENECA

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    Patent Expiration Date : 2027-03-26

    BUDESONIDE; FORMOTEROL FUMARATE DIHYDRATE

    US Patent Number : 8387615

    Drug Substance Claim :

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    Delist Requested :

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    Patent Expiration Date : 2027-03-26

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    ASTRAZENECA

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    Patent Expiration Date : 2029-04-16

    BUDESONIDE; FORMOTEROL FUMARATE DIHYDRATE

    US Patent Number : 8528545*PED

    Drug Substance Claim :

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    Patent Use Description :

    Patent Expiration Date : 2029-04-16

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    ASTRAZENECA

    FORMOTEROL FUMARATE; GLYCOPYRROLATE

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    ASTRAZENECA

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    Patent Expiration Date : 2030-05-28

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    Patent Expiration Date : 2029-03-13

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    US Patent Number : 10085974

    Drug Substance Claim :

    Drug Product Claim : Y

    Application Number : 210595

    Patent Use Code : U-2513

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    Patent Expiration Date : 2029-03-13

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