menu
    • menu

    Find Dyclonine manufacturers, exporters & distributors on PharmaCompass

    Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.

    Virtual Booth

    Contact Supplier

    AbbVie CDMO has been working with global companies to develop, manufacture & scale biopharmaceutical products.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

    Virtual Booth

    Contact Supplier

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    MARKET PLACE

    REF. STANDARDS & IMPURITIES

    PharmaCompass

    Synopsis

    Product SearchProduct Search

    Synopsis

    ACTIVE PHARMA INGREDIENTS

    5

    API Suppliers

    API Suppliers

    3

    USDMF

    US DMFs Filed

    0

    CEP/COS

    CEP/COS Certifications

    0

    JDMF

    JDMFs Filed

    0

    EU WC

    EU WC

    0

    KDMF

    KDMF

    5

    NDC API

    NDC API

    0

    VMF

    NDC API

    2

    Listed Suppliers

    Other Suppliers

    API REF. PRICE (USD/KG)

    $
    $ 0

    MARKET PLACE

    1

    API

    0

    FDF

    0INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    5

    FDF Dossiers

    FDF Dossiers

    4

    FDA Orange Book

    FDA (Orange Book)

    0

    Europe

    Europe

    0

    Canada

    Canada

    0

    Australia

    Australia

    0

    South Africa

    South Africa

    1

    Listed Dossiers

    Listed Dossiers

    0 DRUGS IN DEVELOPMENT

    FDF Dossiers

    DRUG PRODUCT COMPOSITIONS

    REF. STANDARDS OR IMPURITIES

    0

    EDQM

    1

    USP

    0

    JP

    1

    Others

    PATENTS & EXCLUSIVITIES

    0

    US Patents

    0

    US Exclusivities

    0

    Health Canada Patents

    DIGITAL CONTENT

    0

    Data Compilation #PharmaFlow

    0

    Stock Recap #PipelineProspector

    0

    Weekly News Recap #Phispers

    2

    News #PharmaBuzz

    GLOBAL SALES INFORMATION

    US Medicaid

    NA

    Annual Reports

    NA

    Finished Drug Prices

    NA

    63 RELATED EXCIPIENT COMPANIES

    108EXCIPIENTS BY APPLICATIONS

    Chemistry

    Click the arrow to open the dropdown
    read-moreClick the button for full data set
    read-moreClick the button for full data set
    Also known as: 536-43-6, Dyclonine hcl, Dyclone, Dyclothane, Dyclocaine hydrochloride, Tanaclone
    Molecular Formula
    C18H28ClNO2
    Molecular Weight
    325.9  g/mol
    InChI Key
    KNZADIMHVBBPOA-UHFFFAOYSA-N
    FDA UNII
    ZEC193879Q
    Dyclonine
    Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.
    1 2D Structure

    Dyclonine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride
    2.1.2 InChI
    InChI=1S/C18H27NO2.ClH/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19;/h7-10H,2-6,11-15H2,1H3;1H
    2.1.3 InChI Key
    KNZADIMHVBBPOA-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    ZEC193879Q
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Dyclone

    2. Dyclonine

    3. Dyclonine Hcl

    4. Sucrets

    5. Tanac

    2.3.2 Depositor-Supplied Synonyms

    1. 536-43-6

    2. Dyclonine Hcl

    3. Dyclone

    4. Dyclothane

    5. Dyclocaine Hydrochloride

    6. Tanaclone

    7. Dyclonine (hydrochloride)

    8. Diclonina

    9. 4'-butoxy-3-piperidinopropiophenone Hydrochloride

    10. 1-propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)-, Hydrochloride

    11. P-267

    12. Nsc-23018

    13. 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride

    14. Diclonia

    15. Dyclonine Hydrochloride [usp]

    16. Mls000069532

    17. Zec193879q

    18. Dyclocainum

    19. Mfcd00035386

    20. Smr000038382

    21. Dsstox_cid_25323

    22. Dsstox_rid_80802

    23. Dsstox_gsid_45323

    24. Dyclonine Hydrochloride (usp)

    25. Wln: T6ntj A2vr Do4 &gh

    26. Chebi:4725

    27. Dycloninehydrochloride

    28. Dyclonine, Hydrochloride

    29. Ncgc00016498-01

    30. Cas-536-43-6

    31. Einecs 208-633-6

    32. Nsc 23018

    33. 4-n-butoxy-.beta.-(1-piperidyl)propiophenone Hydrochloride

    34. Unii-zec193879q

    35. Sr-01000000032

    36. S 154

    37. C 5422

    38. Dyclopro (tn)

    39. Prestwick_674

    40. Dyclone (tn)

    41. Piperidine, 1-(2-(4-butoxybenzoyl)ethyl), Hydrochloride

    42. Opera_id_1265

    43. Mls001077359

    44. Mls002222240

    45. Schembl317219

    46. Spectrum1500268

    47. Propiophenone, 4'-butoxy-3-piperidino-, Hydrochloride

    48. Chembl1200478

    49. Dtxsid6045323

    50. Hy-b0364a

    51. Hms1568f10

    52. Hms1920k06

    53. Pharmakon1600-01500268

    54. Bcp28402

    55. Nsc23018

    56. Nsc25588

    57. Dyclonine Hydrochloride [mi]

    58. Tox21_110459

    59. Ccg-40231

    60. Nsc-25588

    61. Nsc756745

    62. S2041

    63. Akos015951364

    64. Tox21_110459_1

    65. Ac-8346

    66. Ds-3341

    67. Dyclonine Hydrochloride [mart.]

    68. Dyclonine Hydrochloride [vandf]

    69. Nsc-756745

    70. Dyclonine Hydrochloride [usp-rs]

    71. Dyclonine Hydrochloride [who-dd]

    72. Ncgc00016498-08

    73. Ncgc00094662-01

    74. Ncgc00094662-02

    75. Ncgc00094662-03

    76. Ncgc00094662-04

    77. Sy066681

    78. D4303

    79. Dyclonine Hydrochloride [orange Book]

    80. Ft-0625635

    81. Sw196829-3

    82. Dyclonine Hcl;dyclone;dyclocaine Hydrochloride

    83. D00735

    84. Dyclonine Hydrochloride [usp Monograph]

    85. N12006

    86. A829700

    87. Sr-01000000032-4

    88. W-105718

    89. Q27106453

    90. 4-butoxy-3-piperidinopropiophenone Hydrochloride

    91. 4-n-butoxy-.beta.-piperidonopropiophenone Hydrochloride

    92. 1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone Hydrochloride

    93. 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydron;chloride

    94. 1-propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)hydrochloride

    95. Dyclonine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    96. Dyclonine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 325.9 g/mol
    Molecular Formula C18H28ClNO2
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count8
    Exact Mass325.1808568 g/mol
    Monoisotopic Mass325.1808568 g/mol
    Topological Polar Surface Area29.5 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity292
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anesthetics, Local

    Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)

    Related Excipient Companies

    Upload your portfolio for free, ask us

    Excipients by Applications

    Click here to find the perfect excipient manufacturers by their capabilities

    Coating Systems & Additives

    read-more
    read-more

    Film Formers & Plasticizers

    read-more
    read-more

    Taste Masking

    read-more
    read-more

    Topical

    read-more
    read-more

    Parenteral

    read-more
    read-more

    Fillers, Diluents & Binders

    read-more
    read-more

    Solubilizers

    read-more
    read-more

    Lubricants & Glidants

    read-more
    read-more

    Co-Processed Excipients

    read-more
    read-more

    Granulation

    read-more
    read-more

    Thickeners and Stabilizers

    read-more
    read-more

    Direct Compression

    read-more
    read-more

    Controlled & Modified Release

    read-more
    read-more

    Coloring Agents

    read-more
    read-more

    Chewable & Orodispersible Aids

    read-more
    read-more

    Soft Gelatin

    read-more
    read-more

    Surfactant & Foaming Agents

    read-more
    read-more

    Emulsifying Agents

    read-more
    read-more

    Digital Content read-more

    Create Content with PharmaCompass, ask us

    NEWS #PharmaBuzz

    read-more
    read-more

    Market Place

    Do you need sourcing support? Ask us

    REF. STANDARDS & IMPURITIES

    Upload your portfolio for free, ask us

    USP

    read-more
    read-more

    ABOUT THIS PAGE

    Ask Us for Pharmaceutical Supplier and Partner
    Ask Us, Find A Supplier / Partner
    No Commissions, No Strings Attached, Get Connected for FREE

    What are you looking for?

    How can we help you?

    The request can't be empty

    Please read our Privacy Policy carefully

    You must agree to the privacy policy

    The name can't be empty
    The company can't be empty.
    The email can't be empty Please enter a valid email.
    The mobile can't be empty

    Market Place

    Market Place

    PharmaCompass

    Home

    Market Place

    Menu

    Post Enquiry

    Post Enquiry

    Market Place

    Market Place

    Search