List of Suppliers' Chewable Orodispersible Aids Excipients Application used in dyclonine hydrochloride on PharmaCompass.com

Dyclonine Hydrochloride

EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

5 API Suppliers, 3 USDMF, 5 NDC API, 2 Listed Suppliers

5 API Suppliers
3 USDMF
5 NDC API
2 Listed Suppliers

FINISHED DOSAGE FORMULATIONS

5 FDF Dossiers, 4 FDA Orange Book, 1 Listed Dossiers

5 FDF Dossiers
4 FDA Orange Book
1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

3 Rochem International Inc, 3 SPI Pharma, 4 DKSH, 2 Gangwal Healthcare, 5 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 5 Actylis, 11 BASF, 2 Finar, 2 Gangwal Chemicals, 6 Kerry, 2 Microlex e.U, 2 Pluviaendo, 13 Roquette, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Valens Pharmachem, 1 Zhejiang Huakang Pharmaceutical

relatedExcipients
3 Rochem International Inc
3 SPI Pharma
4 DKSH
2 Gangwal Healthcare
5 Nanjing Well Pharmaceutical
1 Pfanstiehl
5 Actylis
11 BASF
2 Finar
2 Gangwal Chemicals
6 Kerry
2 Microlex e.U
2 Pluviaendo
13 Roquette
1 Shijiazhuang Huaxu Pharmaceutical
1 Valens Pharmachem
1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

13 Film Formers & Plasticizers, 13 Coating Systems & Additives, 12 Taste Masking, 11 Topical, 10 Parenteral, 7 Solubilizers, 7 Fillers, Diluents & Binders, 6 Lubricants & Glidants, 6 Co-Processed Excipients, 5 Granulation, 5 Thickeners and Stabilizers, 4 Direct Compression, 3 Controlled & Modified Release, 2 Coloring Agents, 2 Chewable & Orodispersible Aids, 1 Soft Gelatin, 1 Surfactant & Foaming Agents, 1 Emulsifying Agents

excipientsByApplications
13 Film Formers & Plasticizers
13 Coating Systems & Additives
12 Taste Masking
11 Topical
10 Parenteral
7 Solubilizers
7 Fillers, Diluents & Binders
6 Lubricants & Glidants
6 Co-Processed Excipients
5 Granulation
5 Thickeners and Stabilizers
4 Direct Compression
3 Controlled & Modified Release
2 Coloring Agents
2 Chewable & Orodispersible Aids
1 Soft Gelatin
1 Surfactant & Foaming Agents
1 Emulsifying Agents

DIGITAL CONTENT

2 NEWS #PharmaBuzz

media
2 NEWS #PharmaBuzz

MARKET PLACE

1 APIs

marketPlace
1 APIs

REF. STANDARDS & IMPURITIES

1 USP , 1 Others

otherSolutions
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

64 RELATED EXCIPIENT COMPANIES

109EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 536-43-6, Dyclonine hcl, Dyclone, Dyclothane, Dyclocaine hydrochloride, Tanaclone

Molecular Formula

C₁₈H₂₈ClNO₂

Molecular Weight

325.9 g/mol

InChI Key

KNZADIMHVBBPOA-UHFFFAOYSA-N

FDA UNII

ZEC193879Q

Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.

1 2D Structure

Dyclonine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride

2.1.2 InChI

InChI=1S/C18H27NO2.ClH/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19;/h7-10H,2-6,11-15H2,1H3;1H

2.1.3 InChI Key

KNZADIMHVBBPOA-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2.Cl

2.2 Other Identifiers

2.2.1 UNII

ZEC193879Q

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Dyclone

2. Dyclonine

3. Dyclonine Hcl

4. Sucrets

5. Tanac

2.3.2 Depositor-Supplied Synonyms

1. 536-43-6

2. Dyclonine Hcl

3. Dyclone

4. Dyclothane

5. Dyclocaine Hydrochloride

6. Tanaclone

7. Dyclonine (hydrochloride)

8. Diclonina

9. 4'-butoxy-3-piperidinopropiophenone Hydrochloride

10. 1-propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)-, Hydrochloride

11. P-267

12. Nsc-23018

13. 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride

14. Diclonia

15. Dyclonine Hydrochloride [usp]

16. Mls000069532

17. Zec193879q

18. Dyclocainum

19. Mfcd00035386

20. Smr000038382

21. Dsstox_cid_25323

22. Dsstox_rid_80802

23. Dsstox_gsid_45323

24. Dyclonine Hydrochloride (usp)

25. Wln: T6ntj A2vr Do4 &gh

26. Chebi:4725

27. Dycloninehydrochloride

28. Dyclonine, Hydrochloride

29. Ncgc00016498-01

30. Cas-536-43-6

31. Einecs 208-633-6

32. Nsc 23018

33. 4-n-butoxy-.beta.-(1-piperidyl)propiophenone Hydrochloride

34. Unii-zec193879q

35. Sr-01000000032

36. S 154

37. C 5422

38. Dyclopro (tn)

39. Prestwick_674

40. Dyclone (tn)

41. Piperidine, 1-(2-(4-butoxybenzoyl)ethyl), Hydrochloride

42. Opera_id_1265

43. Mls001077359

44. Mls002222240

45. Schembl317219

46. Spectrum1500268

47. Propiophenone, 4'-butoxy-3-piperidino-, Hydrochloride

48. Chembl1200478

49. Dtxsid6045323

50. Hy-b0364a

51. Hms1568f10

52. Hms1920k06

53. Pharmakon1600-01500268

54. Bcp28402

55. Nsc23018

56. Nsc25588

57. Dyclonine Hydrochloride [mi]

58. Tox21_110459

59. Ccg-40231

60. Nsc-25588

61. Nsc756745

62. S2041

63. Akos015951364

64. Tox21_110459_1

65. Ac-8346

66. Ds-3341

67. Dyclonine Hydrochloride [mart.]

68. Dyclonine Hydrochloride [vandf]

69. Nsc-756745

70. Dyclonine Hydrochloride [usp-rs]

71. Dyclonine Hydrochloride [who-dd]

72. Ncgc00016498-08

73. Ncgc00094662-01

74. Ncgc00094662-02

75. Ncgc00094662-03

76. Ncgc00094662-04

77. Sy066681

78. D4303

79. Dyclonine Hydrochloride [orange Book]

80. Ft-0625635

81. Sw196829-3

82. Dyclonine Hcl;dyclone;dyclocaine Hydrochloride

83. D00735

84. Dyclonine Hydrochloride [usp Monograph]

85. N12006

86. A829700

87. Sr-01000000032-4

88. W-105718

89. Q27106453

90. 4-butoxy-3-piperidinopropiophenone Hydrochloride

91. 4-n-butoxy-.beta.-piperidonopropiophenone Hydrochloride

92. 1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone Hydrochloride

93. 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydron;chloride

94. 1-propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)hydrochloride

95. Dyclonine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

96. Dyclonine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₈H₂₈ClNO₂
Molecular Weight	325.9 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	8
Exact Mass	325.1808568 g/mol
Monoisotopic Mass	325.1808568 g/mol
Topological Polar Surface Area	29.5 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	292
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anesthetics, Local

Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

NDC API

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

FDF Dossiers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

FDA Orange Book

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Dossiers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Related Excipient Companies

Upload your portfolio for free, ask us

Excipients by Applications

Click here to find the perfect excipient manufacturers by their capabilities

Film Formers & Plasticizers

Coating Systems & Additives

Taste Masking

Topical

Parenteral

Solubilizers

Fillers, Diluents & Binders

Lubricants & Glidants

Co-Processed Excipients

Granulation

Thickeners and Stabilizers

Direct Compression

Controlled & Modified Release

Coloring Agents

Chewable & Orodispersible Aids

Soft Gelatin

Surfactant & Foaming Agents

Emulsifying Agents

Digital Content

Create Content with PharmaCompass, ask us

NEWS #PharmaBuzz

Market Place

Do you need sourcing support? Ask us

APIs

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

REF. STANDARDS & IMPURITIES

Upload your portfolio for free, ask us

USP

Others

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

ABOUT THIS PAGE

Market Place

Home

Post Enquiry

Market Place

List of Suppliers' Chewable Orodispersible Aids Excipients Application used in dyclonine hydrochloride on PharmaCompass.com

Dyclonine Hydrochloride

ACCESS ALL DATA

Browse all information

CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

5 API Suppliers

3 USDMF

5 NDC API

2 Listed Suppliers

FINISHED DOSAGE FORMULATIONS

5 FDF Dossiers

4 FDA Orange Book

1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

3 Rochem International Inc

3 SPI Pharma

4 DKSH

2 Gangwal Healthcare

5 Nanjing Well Pharmaceutical

1 Pfanstiehl

5 Actylis

11 BASF

2 Finar

2 Gangwal Chemicals

6 Kerry

2 Microlex e.U

2 Pluviaendo

13 Roquette

1 Shijiazhuang Huaxu Pharmaceutical

1 Valens Pharmachem

1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

13 Film Formers & Plasticizers

13 Coating Systems & Additives

12 Taste Masking

11 Topical

10 Parenteral

7 Solubilizers

7 Fillers, Diluents & Binders

6 Lubricants & Glidants

6 Co-Processed Excipients

5 Granulation

5 Thickeners and Stabilizers

4 Direct Compression

3 Controlled & Modified Release

2 Coloring Agents

2 Chewable & Orodispersible Aids

1 Soft Gelatin

1 Surfactant & Foaming Agents

1 Emulsifying Agents

DIGITAL CONTENT

2 NEWS #PharmaBuzz

MARKET PLACE

1 APIs

REF. STANDARDS & IMPURITIES

1 USP

1 Others

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

GLOBAL SALES INFORMATION

64 RELATED EXCIPIENT COMPANIES

109EXCIPIENTS BY APPLICATIONS

What are you looking for?