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Chemistry

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Also known as: 86408-72-2, Ecabet sodium salt, Ta-2711, Sulfodehydroabietic acid monosodium salt, 51mo2b2osb, Ta-2711e
Molecular Formula
C20H27NaO5S
Molecular Weight
402.5  g/mol
InChI Key
RCVIHORGZULVTN-YGJXXQMASA-M
FDA UNII
51MO2B2OSB

Ecabet Sodium
1 2D Structure

Ecabet Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(4bS,8R,8aR)-8-carboxy-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonate
2.1.2 InChI
InChI=1S/C20H28O5S.Na/c1-12(2)14-10-13-6-7-17-19(3,8-5-9-20(17,4)18(21)22)15(13)11-16(14)26(23,24)25;/h10-12,17H,5-9H2,1-4H3,(H,21,22)(H,23,24,25);/q;+1/p-1/t17-,19-,20-;/m1./s1
2.1.3 InChI Key
RCVIHORGZULVTN-YGJXXQMASA-M
2.1.4 Canonical SMILES
CC(C)C1=C(C=C2C(=C1)CCC3C2(CCCC3(C)C(=O)O)C)S(=O)(=O)[O-].[Na+]
2.1.5 Isomeric SMILES
CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)O)C)S(=O)(=O)[O-].[Na+]
2.2 Other Identifiers
2.2.1 UNII
51MO2B2OSB
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-1-phenanthrenecarboxylic Acid 6-sodium Salt

2. 12-sulfodehydroabietic Acid

3. Ecabet

4. Ta 2711

5. Ta-2711

6. Ta-2711e

2.3.2 Depositor-Supplied Synonyms

1. 86408-72-2

2. Ecabet Sodium Salt

3. Ta-2711

4. Sulfodehydroabietic Acid Monosodium Salt

5. 51mo2b2osb

6. Ta-2711e

7. Gastrom

8. Ecabet Sodium [jan]

9. Unii-51mo2b2osb

10. Ecabet (sodium Salt)

11. Ecabet Monosodium

12. 12-sulfodehydroabietic Acid Monosodium Salt

13. Mls006010228

14. Ecabet Sodium [mart.]

15. Schembl1650174

16. Ecabet Sodium Salt [mi]

17. Ecabet Monosodium [who-dd]

18. Amy18112

19. Bcp11708

20. Mfcd00866896

21. Akos022171692

22. Ccg-268671

23. Smr004701309

24. E1224

25. Q27260913

26. 1-phenanthrenecarboxylic Acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-, (1r-(1-alpha,4a-beta,10a-alpha))-, Monosodium Salt

27. 1-phenanthrenecarboxylic Acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-, Monosodium Salt, (1r,4as,10ar)-

28. Sodium (4bs,8r,8ar)-8-carboxy-2-isopropyl-4b,8-dimethyl-4b,5,6,7,8,8a,9,10-octahydrophenanthrene-3-sulfonate

29. Sodium (4bs,8r,8ar)-8-carboxy-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 402.5 g/mol
Molecular Formula C20H27NaO5S
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass402.14768941 g/mol
Monoisotopic Mass402.14768941 g/mol
Topological Polar Surface Area103 Ų
Heavy Atom Count27
Formal Charge0
Complexity672
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Infective Agents

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)


Anti-Ulcer Agents

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief. (See all compounds classified as Anti-Ulcer Agents.)


Anticarcinogenic Agents

Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved. (See all compounds classified as Anticarcinogenic Agents.)


Protease Inhibitors

Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES). (See all compounds classified as Protease Inhibitors.)


API SUPPLIERS

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21-Apr-2021
11-May-2022
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ABOUT THIS PAGE

Ecabet Sodium Manufacturers

A Ecabet Sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ecabet Sodium, including repackagers and relabelers. The FDA regulates Ecabet Sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ecabet Sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ecabet Sodium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ecabet Sodium Suppliers

A Ecabet Sodium supplier is an individual or a company that provides Ecabet Sodium active pharmaceutical ingredient (API) or Ecabet Sodium finished formulations upon request. The Ecabet Sodium suppliers may include Ecabet Sodium API manufacturers, exporters, distributors and traders.

click here to find a list of Ecabet Sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ecabet Sodium USDMF

A Ecabet Sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Ecabet Sodium active pharmaceutical ingredient (API) in detail. Different forms of Ecabet Sodium DMFs exist exist since differing nations have different regulations, such as Ecabet Sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Ecabet Sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Ecabet Sodium USDMF includes data on Ecabet Sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ecabet Sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Ecabet Sodium suppliers with USDMF on PharmaCompass.

Ecabet Sodium JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Ecabet Sodium Drug Master File in Japan (Ecabet Sodium JDMF) empowers Ecabet Sodium API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Ecabet Sodium JDMF during the approval evaluation for pharmaceutical products. At the time of Ecabet Sodium JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Ecabet Sodium suppliers with JDMF on PharmaCompass.

Ecabet Sodium GMP

Ecabet Sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ecabet Sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ecabet Sodium GMP manufacturer or Ecabet Sodium GMP API supplier for your needs.

Ecabet Sodium CoA

A Ecabet Sodium CoA (Certificate of Analysis) is a formal document that attests to Ecabet Sodium's compliance with Ecabet Sodium specifications and serves as a tool for batch-level quality control.

Ecabet Sodium CoA mostly includes findings from lab analyses of a specific batch. For each Ecabet Sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ecabet Sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Ecabet Sodium EP), Ecabet Sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ecabet Sodium USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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