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Chemistry

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Also known as: 112108-01-7, Sch-39166, Ecopipam [inn], Sch 39166, Sch39166, Chembl298406
Molecular Formula
C19H20ClNO
Molecular Weight
313.8  g/mol
InChI Key
DMJWENQHWZZWDF-PKOBYXMFSA-N
FDA UNII
0X748O646K

Ecopipam
Ecopipam has been used in trials studying the treatment of Tourette's Syndrome, Lesch-Nyhan Disease, Pathological Gambling, and Self-injurious Behavior.
1 2D Structure

Ecopipam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(6aS,13bR)-11-chloro-7-methyl-5,6,6a,8,9,13b-hexahydronaphtho[1,2-a][3]benzazepin-12-ol
2.1.2 InChI
InChI=1S/C19H20ClNO/c1-21-9-8-13-10-16(20)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-17(19)21/h2-5,10-11,17,19,22H,6-9H2,1H3/t17-,19+/m0/s1
2.1.3 InChI Key
DMJWENQHWZZWDF-PKOBYXMFSA-N
2.1.4 Canonical SMILES
CN1CCC2=CC(=C(C=C2C3C1CCC4=CC=CC=C34)O)Cl
2.1.5 Isomeric SMILES
CN1CCC2=CC(=C(C=C2[C@@H]3[C@@H]1CCC4=CC=CC=C34)O)Cl
2.2 Other Identifiers
2.2.1 UNII
0X748O646K
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 6,7,7a,8,9,13b-hexahydro-3-chloro-2-hydroxy-n-methyl-5h-benzo(d)naphtho-(2,1b)azepine

2. Sch 39166

3. Sch-39166

4. Sch39166

2.3.2 Depositor-Supplied Synonyms

1. 112108-01-7

2. Sch-39166

3. Ecopipam [inn]

4. Sch 39166

5. Sch39166

6. Chembl298406

7. 0x748o646k

8. 5h-benzo(d)naphth(2,1-b)azepin-12-ol, 11-chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-, (6as,13br)-

9. Dsstox_cid_23814

10. Dsstox_rid_80075

11. Dsstox_gsid_43814

12. (-)-(6as,13br)-11-chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5h-benzo(d)naphth(2,1-b)azepin-12-ol

13. (6as,13br)-11-chloro-7-methyl-6,6a,7,8,9,13b-hexahydro-5h-benzo[d]naphtho[2,1-b]azepin-12-ol

14. Cas-112108-01-7

15. Ncgc00092362-01

16. Unii-0x748o646k

17. Ecopipam [who-dd]

18. 6,7,7a,8,9,13b-hexahydro-3-chloro-2-hydroxy-n-methyl-5h-benzo(d)naphtho(2,1b)azepine

19. 5h-benzo(d)naphth(2,1-b)azepin-12-ol, 11-chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-, Trans-(-)-

20. Psyrx-101

21. Gtpl3304

22. Schembl1649794

23. Zinc3897

24. Dtxsid8043814

25. Chebi:93645

26. 11-chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6h-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol

27. Tox21_111197

28. Bdbm50004823

29. Tox21_111197_1

30. Db12273

31. (6as,13br)-11-chloro-7-methyl-5,6,6a,8,9,13b-hexahydronaphtho[1,2-a][3]benzazepin-12-ol

32. Ncgc00092362-02

33. Hy-14690

34. Cs-0003511

35. Q5333851

36. Brd-k94270326-004-01-0

37. (6as,13br)-11-chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6h-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol

38. Trans-(-) 11-chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6h-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 313.8 g/mol
Molecular Formula C19H20ClNO
XLogP34.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass313.1233420 g/mol
Monoisotopic Mass313.1233420 g/mol
Topological Polar Surface Area23.5 Ų
Heavy Atom Count22
Formal Charge0
Complexity403
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)


Dopamine Antagonists

Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. (See all compounds classified as Dopamine Antagonists.)


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ABOUT THIS PAGE

Looking for 112108-01-7 / Ecopipam API manufacturers, exporters & distributors?

Ecopipam manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Ecopipam API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ecopipam manufacturer or Ecopipam supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ecopipam manufacturer or Ecopipam supplier.

PharmaCompass also assists you with knowing the Ecopipam API Price utilized in the formulation of products. Ecopipam API Price is not always fixed or binding as the Ecopipam Price is obtained through a variety of data sources. The Ecopipam Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ecopipam

Synonyms

112108-01-7, Sch-39166, Ecopipam [inn], Sch 39166, Sch39166, Chembl298406

Cas Number

112108-01-7

Unique Ingredient Identifier (UNII)

0X748O646K

About Ecopipam

Ecopipam has been used in trials studying the treatment of Tourette's Syndrome, Lesch-Nyhan Disease, Pathological Gambling, and Self-injurious Behavior.

Ecopipam Manufacturers

A Ecopipam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ecopipam, including repackagers and relabelers. The FDA regulates Ecopipam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ecopipam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ecopipam Suppliers

A Ecopipam supplier is an individual or a company that provides Ecopipam active pharmaceutical ingredient (API) or Ecopipam finished formulations upon request. The Ecopipam suppliers may include Ecopipam API manufacturers, exporters, distributors and traders.

Ecopipam GMP

Ecopipam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ecopipam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ecopipam GMP manufacturer or Ecopipam GMP API supplier for your needs.

Ecopipam CoA

A Ecopipam CoA (Certificate of Analysis) is a formal document that attests to Ecopipam's compliance with Ecopipam specifications and serves as a tool for batch-level quality control.

Ecopipam CoA mostly includes findings from lab analyses of a specific batch. For each Ecopipam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ecopipam may be tested according to a variety of international standards, such as European Pharmacopoeia (Ecopipam EP), Ecopipam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ecopipam USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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