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1. Sodium Edetate
2. 64-02-8
3. Edta Tetrasodium
4. Ethylenediaminetetraacetic Acid Tetrasodium Salt
5. Tetrasodium Edta
6. Edta Sodium
7. Edta Tetrasodium Salt
8. Sodium Edta
9. Complexone
10. Edta, Tetrasodium
11. Calsol
12. Versene 100
13. Endrate Tetrasodium
14. Tetrasodium Edetate
15. Sequestrene
16. Tetrine
17. Syntes 12a
18. Trilon B
19. Tetrasodium Ethylenediaminetetraacetate
20. Versene 220
21. Na4edta
22. Edetate Sodium [usan]
23. Tetrasodium Salt Of Edta
24. Nervanaid
25. Nullapo
26. Sodium Ethylenediaminetetraacetate
27. 67401-50-7
28. Mp1j8420lu
29. Glycine, N,n'-1,2-ethanediylbis(n-(carboxymethyl)-, Sodium Salt (1:4)
30. Edta, Tetrasodium Salt, Ultra Pure
31. Aquamollin
32. Irgalon
33. Komplexon
34. Nullapon
35. Questex
36. Tetracemin
37. Tyclarosol
38. Distol
39. Edetate Sodium (usan)
40. Ergon
41. Kalex
42. Natrii Edetas
43. Versene Beads
44. Versene Flake
45. Versene Powder
46. Sequestrene St
47. Aquamoline Bc
48. Metaquest C
49. Nervanaid B
50. Nullapon B
51. Kutrilon Cs
52. Natrium Aedeticum
53. Syntron B
54. Cheelox Bf
55. Clewat T
56. Conigon Bc
57. Nullapon Bfc
58. Sequestrene 30a
59. Celon E
60. Celon H
61. Ergon B
62. Questex 4
63. Celon Is
64. Sequestrene Na 4
65. Distol 8
66. Nervanaid B Liquid
67. Nervanaid-b Liquid
68. Hamp-ene Na4
69. Warkeelate S-42
70. Nullapon Bfc Xonc
71. Chemcolox 200
72. Versene 67
73. Perma Kleer 100
74. Perma-kleer 100
75. Ethylene Diamine Tetra Acetic Acid Tetra Sodium Salt
76. Nullapon Bf-12
77. Nullapon Bf-78
78. Warkeelate Ps-42
79. Warkeelate Ps-43
80. Warkeelate Ps-47
81. Clewat S 2
82. Edathanil Tetrasodium
83. Buffer Concentrate, Ph 7.00
84. Nullapon Bfc Liquid
85. Cheelox Bf-12
86. Cheelox Bf-13
87. Cheelox Bf-78
88. Cheelox Br-33
89. Chelest 400
90. Kemplex 100
91. Perma-kleer Tetra Cp
92. Sodium (edetate De)
93. Perma Kleer Tetra Cp
94. Chelon 100
95. Hamp-ene 100s
96. Caswell No. 846
97. Glycine, N,n'-1,2-ethanediylbis(n-(carboxymethyl)-, Tetrasodium Salt
98. Hamp-ene 100
99. Hamp-ene 215
100. Hamp-ene 220
101. Tetracemate Tetrasodium
102. Tetrasodium Salt Edta
103. Chemcolox 240 Powder
104. Tetrasodium Ethylenediaminetetraacetate Trihydrate
105. Nullapon Bfc Xonc Beads
106. Perma Kleer 50 Crystals
107. Ethylenediaminetetraaceticacidtetrasodiumsalt
108. Versene Powder Tetra Sodium
109. Edetic Acid Tetrasodium Salt
110. Ccris 6797
111. Glycine, N,n'-1,2-ethanediylbis[n-(carboxymethyl)-, Tetrasodium Salt
112. Hsdb 5003
113. 8013-51-2
114. Einecs 200-573-9
115. Tetrasodium Ethylenediaminetetracetate
116. Sodium Ethylenediaminetetraacetic Acid
117. Epa Pesticide Chemical Code 039107
118. Unii-mp1j8420lu
119. Edta Tetrasodium Salt Hydrate
120. Ethylenediamine Tetraacetic Acid Tetrasodium Salt
121. Tetrasodium (ethylenedinitrilo)tetraacetate
122. Ai3-17182
123. Ethylene Diamine Tetraacetic Acid Sodium Salt
124. Tetranatrium Ethylendiamintetraacetat [czech]
125. Sodium Salt Of Ethylenediaminetetraacetic Acid
126. Tetrasodium Ethylenediaminetetraacetate Hydrate
127. Tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate
128. Edetate Tetrasodium
129. Ethylenebis(iminodiacetic Acid) Tetrasodium Salt
130. Ethylenediaminetetraacetic Acid, Tetrasodium Salt
131. Tetrasodium Salt Of Edta Solution
132. Tetrasodium Salt Of Ethylenediaminetetracetic Acid
133. N,n'-ethylenediaminediacetic Acid Tetrasodium Salt
134. Tetranatrium Ethylendiamintetraacetat
135. (ethylenedinitrilo)tetraacetic Acid Tetrasodium Salt
136. Tetrasodium Ethylenediamine-n,n,n',n'-tetraacetate
137. Tetrasodium(ethylenedinitrilo)tetraacetate
138. Edta 4na
139. Edetate [vandf]
140. 7379-28-4
141. N,n'-1,2-ethanediylbis(n-(carboxymethyl)glycine) Tetrasodium Salt
142. Ec 200-573-9
143. Edetate Sodium [ii]
144. Edetate Sodium [hsdb]
145. Edetate Sodium [vandf]
146. Tetrasodium Edta [inci]
147. Acetic Acid, (ethylenedinitrilo)tetra-, Tetrasodium Salt
148. Chembl2104344
149. Dtxsid3026350
150. Edta Tetrasodium [vandf]
151. Ethylenediaminetetraacetic Acid, Tetrasodium Salt Solution
152. Sodium Edetate [who-dd]
153. Edta Tetrasodium Salt [mi]
154. Sodium Edetate [green Book]
155. Tetrasodium Edetate [mart.]
156. Glycine, N,n'-1,2-ethanediylbis(n-carboxymethyl-, Tetrasodium Salt
157. Mfcd00012460
158. N,n'-1,2-ethanediylbis(n-(carboxymethyl)glycine), Tetrasodium Salt
159. Akos015960370
160. Tetrasodium Edta Tetrahydrate, Powder
161. Db13404
162. Ac-10617
163. E0099
164. E0565
165. Ft-0626315
166. Sodium Salt Of Ethylenediamine Tetracetic Acid
167. D03946
168. E75734
169. Ethylenediaminetetraacetic Acid Tetra Sodium Salt
170. A834617
171. Acetic Acid, (ethylenedinitrilo)tetra-, Sodium Salt
172. J-006165
173. J-521350
174. Q27284152
175. Ethylenediamine Tetraacetic Acid Tetrasodiumsalt, 86-88%
176. Edta, Tetrasodium Tetrahydrate Salt - Cas 13235-36-4
177. Tetrasodium 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate
178. Tetrasodium 2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate
179. Tetrasodium 2-[2-[bis(2-oxidanidyl-2-oxidanylidene-ethyl)amino]ethyl-(2-oxidanidyl-2-oxidanylidene-ethyl)amino]ethanoate
| Molecular Weight | 380.17 g/mol |
|---|---|
| Molecular Formula | C10H12N2Na4O8 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 7 |
| Exact Mass | 380.01844247 g/mol |
| Monoisotopic Mass | 380.01844247 g/mol |
| Topological Polar Surface Area | 167 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 293 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 5 |
Tetrasodium edetate used in dust as sequestering agent should not be applied to eye unless first neutralized, because it forms solution sufficiently alkaline to be injurious to eye.
Grant, W.M. Toxicology of the Eye. 3rd ed. Springfield, IL: Charles C. Thomas Publisher, 1986., p. 390
/Investigators/ examined the efficacy of tetrasodium EDTA in eradicating biofilms derived from salivary inocula or pure cultures of Candida albicans on discs of polymethyl methacrylate (PMMA) denture base or on toothbrushes that had been used normally for 4-8 weeks. Its efficiency in virus neutralization was also determined. Overnight (16 hr) treatment with 4% (w/v) tetrasodium EDTA solution reduced salivary and C. albicans biofilm viable counts by > or =99%. Biofilm removal was confirmed using confocal laser scanning microscopy. Presence/absence of sucrose during biofilm formation had no effect on killing efficacy. Prolonged treatment of PMMA with tetrasodium EDTA did not influence subsequent formation of C. albicans biofilms or affect surface roughness of the PMMA, but it reduced subsequent biofilm formation from a salivary inoculum. Infectivities of herpes simplex virus and polio virus suspensions were reduced by >99.99% by treatment for 1 and 2 hr, respectively. Tetrasodium EDTA solution efficiently disinfected toothbrushes and PMMA discs, with the detachment of biofilms, and rapidly neutralized both nonenveloped and enveloped viruses. Dentures and toothbrushes become contaminated by bacterial biofilms and by viruses. There is a need for disinfection methods that are rapidly effective, cost-effective, nontoxic and easily implemented. These studies indicate that tetrasodium EDTA solution has disinfection applications in the oral care field.
PMID:18045435 Devine DA et al; J Appl Microbiol 103 (6): 2516-24 (2007)
Central venous catheter (CVC)-related bloodstream infections (BSIs) are known to increase rates of morbidity and mortality in both inpatients and outpatients, including hematology-oncology patients and those undergoing hemodialysis or home infusion therapy. Biofilm-associated organisms on the lumens of these catheters have reduced susceptibility to antimicrobial chemotherapy. This study tested the efficacy of tetrasodium EDTA as a catheter lock solution on biofilms of several clinically relevant microorganisms. Biofilms of Staphylococcus epidermidis, methicillin-resistant S. aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and Candida albicans were grown to levels of approximately 1 x 10+5 colony-forming units (CFU) cm(-1) on CVC segments in a model system, then subjected to the tetrasodium EDTA lock treatment. Comparisons of biofilms before and after exposure to the 40-mg mL(-1) tetrasodium EDTA lock for 21 hours showed that the biofilm viable cell counts of all organisms tested were significantly reduced (P < 0.05) after exposure to the treatment. Antimicrobial lock treatment using 40 mg mL(-1) of tetrasodium EDTA for at least 21 hours could significantly reduce or potentially eradicate CVC-associated biofilms of clinically relevant microorganisms.
PMID:16018425 Percival SL et al; Infect Control Hosp Epidemiol 26 (6): 515-9 (2005)
Exptl use: trilon b had significant therapeutic effect when injected iv at 50 mg/kg into rabbits and 150-175 mg/kg ip into mice poisoned with lithium chloride.
Samilov N et al; BYULL EKSP-BIOL MED 74 (8): 46 (1972)
...Tetrasodium edta is effective for treating lime burns of cornea and /as chelating agent/ for treating hypercalcemia patients by removing blood calcium.
Luckey, T.D. and B. Venugopal. Metal Toxicity in Mammals, 1. New York: Plenum Press, 1977., p. 119
S - Sensory organs
S01 - Ophthalmologicals
S01X - Other ophthalmologicals
S01XA - Other ophthalmologicals
S01XA05 - Sodium edetate
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