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PMC Isochem Elbasvir

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Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

4 API Suppliers, 1 KDMF, 1 NDC API, 4 Listed Suppliers

4 API Suppliers
1 KDMF
1 NDC API
4 Listed Suppliers

INTERMEDIATES

8 Intermediates Suppliers

8 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

3 FDF Dossiers, 1 FDA Orange Book, 1 Europe, 1 Listed Dossiers

3 FDF Dossiers
1 FDA Orange Book
1 Europe
1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 13 SPI Pharma, 1 Seqens, 4 DKSH, 1 PMC Isochem, 5 Faran Shimi Pharmaceutical, 2 Boai NKY Pharmaceuticals Ltd, 9 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 2 Actylis, 1 Alcedo Pharmachem, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 9 BASF, 1 Bioplus Life Sciences, 5 DFE Pharma, 5 Gangwal Chemicals, 1 Huzhou Sunflower Pharmaceutical, 1 Ideal Cures Pvt Ltd, 2 Ingredion Pharma Solutions, 19 Kerry, 12 Microlex e.U, 1 Novo Excipients, 1 Pharmatrans-Sanaq, 5 Pluviaendo, 3 Prachin Chemical, 13 Roquette, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shijiazhuang Huaxu Pharmaceutical, 10 Sigachi Industries, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

63 Fillers, Diluents & Binders, 32 Direct Compression, 18 Granulation, 15 Co-Processed Excipients, 14 Disintegrants & Superdisintegrants, 14 Taste Masking, 13 Thickeners and Stabilizers, 13 Lubricants & Glidants, 11 Chewable & Orodispersible Aids, 10 Coating Systems & Additives, 9 Film Formers & Plasticizers, 7 Parenteral, 6 Controlled & Modified Release, 5 Emulsifying Agents, 3 Solubilizers, 3 Coloring Agents, 2 API Stability Enhancers, 2 Surfactant & Foaming Agents, 2 Topical, 2 Rheology Modifiers

DIGITAL CONTENT

2 DATA COMPILATION #PharmaFlow, 32 NEWS #PharmaBuzz

media
2 DATA COMPILATION #PharmaFlow
32 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 Finished Drug Prices, 6 Annual Reports

globalSalesInformation
1 Finished Drug Prices
6 Annual Reports

MARKET PLACE

3 APIs

marketPlace
3 APIs

PATENTS & EXCLUSIVITIES

2 US Patents, 1 US Exclusivities

patents
2 US Patents
1 US Exclusivities

Elbasvir

Synopsis

ACTIVE PHARMA INGREDIENTS

4

API Suppliers

0

USDMF

0

CEP/COS

CEP/COS Certifications

0

JDMF

0

EU WC

1

KDMF

1

NDC API

0

VMF

4

Listed Suppliers

API REF. PRICE (USD/KG)

$

$ 0

MARKET PLACE

3

API

0

FDF

8INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

3

FDF Dossiers

1

FDA Orange Book

FDA (Orange Book)

1

Europe

0

Canada

0

Australia

0

South Africa

1

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

2

US Patents

1

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

2

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

32

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

NA

Annual Reports (USD Million)

3,335

Finished Drug Prices

142 RELATED EXCIPIENT COMPANIES

244EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Dtxsid10160043, Akos025401976, Ac-27741, Ac-28948

Molecular Formula

C₄₉H₅₅N₉O₇

Molecular Weight

882.0 g/mol

InChI Key

UXXFHLOGQYUBLD-JFOPJMDSSA-N

Elbasvir

1 2D Structure

Elbasvir

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

methyl N-[(2S)-1-[(2S)-2-[4-[(6S)-3-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-4H-imidazol-4-yl]-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazin-10-yl]-2H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate

2.1.2 InChI

InChI=1S/C49H55N9O7/c1-27(2)41(54-48(61)63-5)45(59)56-20-10-14-37(56)43-50-25-34(52-43)30-17-19-36-32(22-30)23-39-33-18-16-31(24-40(33)65-47(58(36)39)29-12-8-7-9-13-29)35-26-51-44(53-35)38-15-11-21-57(38)46(60)42(28(3)4)55-49(62)64-6/h7-9,12-13,16-19,22-28,35,37-38,41-43,47H,10-11,14-15,20-21H2,1-6H3,(H,54,61)(H,55,62)/t35?,37-,38-,41-,42-,43?,47-/m0/s1

2.1.3 InChI Key

UXXFHLOGQYUBLD-JFOPJMDSSA-N

2.1.4 Canonical SMILES

CC(C)C(C(=O)N1CCCC1C2N=CC(=N2)C3=CC4=C(C=C3)N5C(OC6=C(C5=C4)C=CC(=C6)C7C=NC(=N7)C8CCCN8C(=O)C(C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC

2.1.5 Isomeric SMILES

CC(C)[C@@H](C(=O)N1CCC[C@H]1C2N=CC(=N2)C3=CC4=C(C=C3)N5[C@@H](OC6=C(C5=C4)C=CC(=C6)C7C=NC(=N7)[C@@H]8CCCN8C(=O)[C@H](C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Dtxsid10160043

2. Akos025401976

3. Ac-27741

4. Ac-28948

2.3 Create Date

2013-09-21

3 Chemical and Physical Properties

Molecular Formula	C₄₉H₅₅N₉O₇
Molecular Weight	882.0 g/mol
XLogP3	5.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	13
Exact Mass	881.42244513 g/mol
Monoisotopic Mass	881.42244513 g/mol
Topological Polar Surface Area	181 Å²
Heavy Atom Count	65
Formal Charge	0
Complexity	1900
Isotope Atom Count	0
Defined Atom Stereocenter Count	5
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

API SUPPLIERS

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KDMF

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INTERMEDIATES SUPPLIERS

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FDF Dossiers

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FDA Orange Book

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Europe

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Excipients by Applications

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Fillers, Diluents & Binders

Direct Compression

Granulation

Co-Processed Excipients

Disintegrants & Superdisintegrants

Taste Masking

Thickeners and Stabilizers

Lubricants & Glidants

Chewable & Orodispersible Aids

Coating Systems & Additives

Film Formers & Plasticizers

Parenteral

Controlled & Modified Release

Emulsifying Agents

Solubilizers

Coloring Agents

API Stability Enhancers

Surfactant & Foaming Agents

Topical

Rheology Modifiers

Digital Content

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DATA COMPILATION #PharmaFlow

NEWS #PharmaBuzz

Global Sales Information

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Finished Drug Prices

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Annual Reports

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Market Place

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APIs

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Patents & EXCLUSIVITIES

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US Patents

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US Exclusivities

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