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Chemistry

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Also known as: 69-25-0, Eledone peptide, Eld 950, Eld-950, Eledoisin [inn], Chembl373569
Molecular Formula
C54H85N13O15S
Molecular Weight
1188.4  g/mol
InChI Key
AYLPVIWBPZMVSH-FCKMLYJASA-N

Eledoisin
A peptide extracted from the posterior salivary glands of certain small octopi (Eledone spp., Mollusca), or obtained by synthesis. Its actions resemble those of SUBSTANCE P; it is a potent vasodilator and increases capillary permeability. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1364)
1 2D Structure

Eledoisin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(3S)-3-[[(2S)-6-amino-2-[[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
2.1.2 InChI
InChI=1S/C54H85N13O15S/c1-7-30(4)44(53(81)57-27-42(70)60-36(24-29(2)3)49(77)61-33(45(56)73)20-23-83-6)66-50(78)37(25-32-14-9-8-10-15-32)63-46(74)31(5)58-48(76)38(26-43(71)72)64-47(75)34(16-11-12-21-55)62-51(79)39(28-68)65-52(80)40-17-13-22-67(40)54(82)35-18-19-41(69)59-35/h8-10,14-15,29-31,33-40,44,68H,7,11-13,16-28,55H2,1-6H3,(H2,56,73)(H,57,81)(H,58,76)(H,59,69)(H,60,70)(H,61,77)(H,62,79)(H,63,74)(H,64,75)(H,65,80)(H,66,78)(H,71,72)/t30-,31-,33-,34-,35-,36-,37-,38-,39-,40-,44-/m0/s1
2.1.3 InChI Key
AYLPVIWBPZMVSH-FCKMLYJASA-N
2.1.4 Canonical SMILES
CCC(C)C(C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C3CCC(=O)N3
2.1.5 Isomeric SMILES
CC[C@H](C)[C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCC(=O)N3
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. 69-25-0

2. Eledone Peptide

3. Eld 950

4. Eld-950

5. Eledoisin [inn]

6. Chembl373569

7. Eledoisin (inn)

8. Eledoisinum

9. Eledoisina

10. Eledoisine

11. 5-oxo-l-prolyl-l-prolyl-l-seryl-l-lysyl-l-alpha-aspartyl-l-alanyl-l-phenylalanyl-l-isoleucylglycyl-l-leucyl-l-methioninamide

12. Eledoisine [inn-french]

13. Eledoisina [inn-spanish]

14. Fi 6225 Tf/ocoa

15. Unii-oky3285j18

16. Brn 4796573

17. Dsstox_cid_26926

18. Dsstox_rid_82022

19. Dsstox_gsid_46926

20. Schembl158143

21. Gtpl2086

22. Dtxsid1046926

23. Chebi:135903

24. Oky3285j18

25. Tox21_112815

26. Bdbm50194558

27. Akos024456851

28. Cas-69-25-0

29. Ncgc00167276-01

30. Ntoc00000202-01

31. 5-oxo-l-prolyl-l-prolyl-l-seryl-l-lysyl-l-aspartyl-l-alanyl-l-phenylalanyl-l-isoleucylglycyl-l-leucyl-l-methioninamide

32. C20029

33. D07936

34. 069e250

35. 076e373

36. Q5358600

2.3 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 1188.4 g/mol
Molecular Formula C54H85N13O15S
XLogP3-3.6
Hydrogen Bond Donor Count14
Hydrogen Bond Acceptor Count17
Rotatable Bond Count36
Exact Mass1187.60088023 g/mol
Monoisotopic Mass1187.60088023 g/mol
Topological Polar Surface Area463 Ų
Heavy Atom Count83
Formal Charge0
Complexity2270
Isotope Atom Count0
Defined Atom Stereocenter Count11
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Neurotransmitter Agents

Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. (See all compounds classified as Neurotransmitter Agents.)


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Looking for 69-25-0 / Eledoisin API manufacturers, exporters & distributors?

Eledoisin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Eledoisin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Eledoisin manufacturer or Eledoisin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Eledoisin manufacturer or Eledoisin supplier.

PharmaCompass also assists you with knowing the Eledoisin API Price utilized in the formulation of products. Eledoisin API Price is not always fixed or binding as the Eledoisin Price is obtained through a variety of data sources. The Eledoisin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Eledoisin

Synonyms

69-25-0, Eledone peptide, Eld 950, Eld-950, Eledoisin [inn], Chembl373569

Cas Number

69-25-0

About Eledoisin

A peptide extracted from the posterior salivary glands of certain small octopi (Eledone spp., Mollusca), or obtained by synthesis. Its actions resemble those of SUBSTANCE P; it is a potent vasodilator and increases capillary permeability. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1364)

Eledoisin Manufacturers

A Eledoisin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Eledoisin, including repackagers and relabelers. The FDA regulates Eledoisin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Eledoisin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Eledoisin Suppliers

A Eledoisin supplier is an individual or a company that provides Eledoisin active pharmaceutical ingredient (API) or Eledoisin finished formulations upon request. The Eledoisin suppliers may include Eledoisin API manufacturers, exporters, distributors and traders.

Eledoisin GMP

Eledoisin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Eledoisin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Eledoisin GMP manufacturer or Eledoisin GMP API supplier for your needs.

Eledoisin CoA

A Eledoisin CoA (Certificate of Analysis) is a formal document that attests to Eledoisin's compliance with Eledoisin specifications and serves as a tool for batch-level quality control.

Eledoisin CoA mostly includes findings from lab analyses of a specific batch. For each Eledoisin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Eledoisin may be tested according to a variety of international standards, such as European Pharmacopoeia (Eledoisin EP), Eledoisin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Eledoisin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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