Find Elinzanetant manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Weekly News Recap #Phispers

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Unii-nzw2bow35n, 929046-33-3, Nt-814, Elinzanetant [inn], Elinzanetant [usan], Nzw2bow35n
Molecular Formula
C33H35F7N4O3
Molecular Weight
668.6  g/mol
InChI Key
DWRIJNIPBUFCQS-DQEYMECFSA-N
FDA UNII
NZW2BOW35N

Elinzanetant
1 2D Structure

Elinzanetant

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[6-[(7S,9aS)-7-(hydroxymethyl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide
2.1.2 InChI
InChI=1S/C33H35F7N4O3/c1-19-9-23(34)5-6-26(19)27-13-29(44-16-25-18-47-8-7-43(25)15-24(44)17-45)41-14-28(27)42(4)30(46)31(2,3)20-10-21(32(35,36)37)12-22(11-20)33(38,39)40/h5-6,9-14,24-25,45H,7-8,15-18H2,1-4H3/t24-,25-/m0/s1
2.1.3 InChI Key
DWRIJNIPBUFCQS-DQEYMECFSA-N
2.1.4 Canonical SMILES
CC1=C(C=CC(=C1)F)C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CC5COCCN5CC4CO
2.1.5 Isomeric SMILES
CC1=C(C=CC(=C1)F)C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4C[C@H]5COCCN5C[C@H]4CO
2.2 Other Identifiers
2.2.1 UNII
NZW2BOW35N
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Unii-nzw2bow35n

2. 929046-33-3

3. Nt-814

4. Elinzanetant [inn]

5. Elinzanetant [usan]

6. Nzw2bow35n

7. Bay3427080

8. Bay-3427080

9. 2-(3,5-bis(trifluoromethyl)phenyl)-n-(4-(4-fluoro-2-methylphenyl)-6-((7s,9as)-7-(hydroxymethyl)hexahydropyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,2-dimethylpropanamide

10. 2-[3,5-bis(trifluoromethyl)phenyl]-n-{4-(4-fluoro-2-methylphenyl)-6-[(7s,9as)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1h)-yl]-3-pyridinyl}-n,2-dimethylpropanamide

11. Elinzanetant [who-dd]

12. Schembl303180

13. Chembl4802157

14. Dtxsid101337049

15. Ex-a6225

16. Who 10952

17. Hy-109171

18. Cs-0116361

19. 2-[3,5-bis(trifluoromethyl)phenyl]-n-{4-(4-fluoro-2-methylphenyl)-6-[(7s,9as)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1h)-yl]pyridin-3-yl}-n,2-dimethylpropanamide

20. Benzamide, 3-(5-methyl-2-tbenzeneacetamide, N-(4-(4-fluoro-2-methylphenyl)-6-((7s,9as)-hexahydro-7-(hydroxymethyl)pyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,.alpha.,.alpha.-trimethyl-3,5-bis(trifluoromethyl)-

21. Benzamide, 3-(5-methyl-2-tbenzeneacetamide, N-(4-(4-fluoro-2-methylphenyl)-6-((7s,9as)-hexahydro-7-(hydroxymethyl)pyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,alpha,alpha-trimethyl-3,5-bis(trifluoromethyl)-

22. N-[6-[(7s,9as)-7-(hydroxymethyl)-3,4,6,7,9,9a-hexahydro-1h-pyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-2-[3,5-bis(trifluoromethyl)phenyl]-n,2-dimethylpropanamide

2.4 Create Date
2007-05-22
3 Chemical and Physical Properties
Molecular Weight 668.6 g/mol
Molecular Formula C33H35F7N4O3
XLogP35.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count13
Rotatable Bond Count6
Exact Mass668.25973813 g/mol
Monoisotopic Mass668.25973813 g/mol
Topological Polar Surface Area69.1 Ų
Heavy Atom Count47
Formal Charge0
Complexity1060
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

Drugs in Development

read-more
read-more

Details:

BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.


Lead Product(s): Elinzanetant

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: BAY3427080

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 15, 2024

blank

01

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Details : BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.

Brand Name : BAY3427080

Molecule Type : Small molecule

Upfront Cash : Not Applicable

October 15, 2024

blank

Details:

BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.


Lead Product(s): Elinzanetant

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: BAY3427080

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 09, 2024

blank

02

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Details : BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.

Brand Name : BAY3427080

Molecule Type : Small molecule

Upfront Cash : Not Applicable

October 09, 2024

blank

Details:

BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.


Lead Product(s): Elinzanetant

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: BAY3427080

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 10, 2024

blank

03

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Details : BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.

Brand Name : BAY3427080

Molecule Type : Small molecule

Upfront Cash : Not Applicable

September 10, 2024

blank

Details:

BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.


Lead Product(s): Elinzanetant

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: BAY3427080

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 04, 2024

blank

04

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Details : BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.

Brand Name : BAY3427080

Molecule Type : Small molecule

Upfront Cash : Not Applicable

September 04, 2024

blank

Details:

BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.


Lead Product(s): Elinzanetant

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: BAY3427080

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 01, 2024

blank

05

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Details : BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.

Brand Name : BAY3427080

Molecule Type : Small molecule

Upfront Cash : Not Applicable

August 01, 2024

blank

Details:

BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.


Lead Product(s): Elinzanetant

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: BAY3427080

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 16, 2024

blank

06

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Details : BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms.

Brand Name : BAY3427080

Molecule Type : Small molecule

Upfront Cash : Not Applicable

May 16, 2024

blank

Details:

BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for moderate to severe vasomotor symptoms (VMS, also known as hot flashes.


Lead Product(s): Elinzanetant

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: BAY3427080

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 08, 2024

blank

07

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Details : BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for moderate to severe vasomotor symptoms (VMS, also known as hot flashes.

Brand Name : BAY3427080

Molecule Type : Small molecule

Upfront Cash : Not Applicable

May 08, 2024

blank

Details:

BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms (known as hot flashes).


Lead Product(s): Elinzanetant

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: BAY3427080

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 19, 2024

blank

08

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Details : BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms (known as hot flashes).

Brand Name : BAY3427080

Molecule Type : Small molecule

Upfront Cash : Not Applicable

March 19, 2024

blank

Details:

BAY-3427080 (elinzanetant) is a first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is in phase 2 clinical development for the treatment of sleep disturbances associated with menopause.


Lead Product(s): Elinzanetant

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: BAY-3427080

Study Phase: Phase IIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 08, 2024

blank

09

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Details : BAY-3427080 (elinzanetant) is a first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is in phase 2 clinical development for the treatment of sleep disturbances associated with menopause.

Brand Name : BAY-3427080

Molecule Type : Small molecule

Upfront Cash : Not Applicable

January 08, 2024

blank

Details:

BAY-3427080 (elinzanetant) is a first dual NK-1,3 receptor antagonist in late-stage clinical development for moderate to severe VMS associated with menopause, administered orally once daily.


Lead Product(s): Elinzanetant

Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Brand Name: BAY-3427080

Study Phase: Phase IIIProduct Type: Small molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 08, 2024

blank

10

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Bayer AG

Germany
arrow
Compamed
Not Confirmed

Details : BAY-3427080 (elinzanetant) is a first dual NK-1,3 receptor antagonist in late-stage clinical development for moderate to severe VMS associated with menopause, administered orally once daily.

Brand Name : BAY-3427080

Molecule Type : Small molecule

Upfront Cash : Not Applicable

January 08, 2024

blank
click full view
Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Digital Content read-more

Create Content with PharmaCompass, ask us

STOCK RECAP #PipelineProspector

read-more
read-more

NEWS #PharmaBuzz

read-more
read-more

ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty