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Also known as: 496775-62-3, Revolade, Promacta, Eltrombopag (olamine), Unii-4u07f515lg, Sb-497115-gr
Molecular Formula
C29H36N6O6
Molecular Weight
564.6  g/mol
InChI Key
DJMJHIKGMVJYCW-UHFFFAOYSA-N
FDA UNII
4U07F515LG

Eltrombopag
Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
1 2D Structure

Eltrombopag

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-aminoethanol;3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid
2.1.2 InChI
InChI=1S/C25H22N4O4.2C2H7NO/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33;2*3-1-2-4/h4-13,28,30H,1-3H3,(H,32,33);2*4H,1-3H2
2.1.3 InChI Key
DJMJHIKGMVJYCW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N=NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(=O)O)C.C(CO)N.C(CO)N
2.2 Other Identifiers
2.2.1 UNII
4U07F515LG
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (1,1'-biphenyl)-3-carboxylic Acid, 3'-((2z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol-4-ylidene)hydrazino)-2'-hydroxy-

2. Ddl-701

3. Eltrombopag

4. Promacta

5. Revolade

6. Sb-497 115

7. Sb-497-115

8. Sb497115

2.3.2 Depositor-Supplied Synonyms

1. 496775-62-3

2. Revolade

3. Promacta

4. Eltrombopag (olamine)

5. Unii-4u07f515lg

6. Sb-497115-gr

7. Eltrombopag Diethanolamine Salt

8. 496775-62-3 (olamine)

9. Eltrombopag (as Olamine)

10. 4u07f515lg

11. Sb-497115gr

12. Eltrombopag Compd With 2-aminoethanol (1:2)

13. Eltrombopag Diethanolamine Salt;sb-497115gr

14. (z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxyiic Acid;2-aminoethan-1-ol (1:2)

15. 3'-((2z)-2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene)diazanyl)-2'-hydroxybiphenyl-3-carboxylic Acid Compound With 2-aminoethanol (1:2)

16. Promacta Olamine

17. Eltrombopagolamine

18. Eltrombopag Olamine [usan:jan]

19. Promacta (tn)

20. Sb 497115gr

21. Schembl210183

22. Amy267

23. Chembl3989691

24. Schembl16207741

25. Schembl23458316

26. Eltrombopag Olamine (jan/usan)

27. Eltrombopag Olamine [jan]

28. Eltrombopag Olamine [usan]

29. Bcp07055

30. Eltrombopag Olamine [mart.]

31. Eltrombopag Olamine [who-dd]

32. Hy-15306a

33. Mfcd22380664

34. S2229

35. Akos025396658

36. Akos037515856

37. Ccg-270074

38. Cs-1566

39. Sb19102

40. Eltrombopag Olamine [orange Book]

41. 2-aminoethan-1-ol Hemi((e)-3'-(2-(2-(3,4-dimethylphenyl)-5-methyl-3-oxo-2,3-dihydro-1h-pyrazol-4-yl)hydrazono)-2'-oxo-2',3'-dihydro-[1,1'-biphenyl]-3-carboxylate)

42. Ac-26286

43. Bs-17370

44. Ft-0773802

45. D03978

46. A904098

47. Q27260489

48. Eltrombopag Compd With 2-aminoethanol (1:2) [mi]

49. (1,1'-biphenyl)-3-carboxylic Acid, 3'-((2z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol-4-ylidene)hydrazino)-2'-hydroxy, Compound With 2-aminoethanol (1:2)

50. (1,1'-biphenyl)-3-carboxylic Acid, 3'-((2z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol-4-ylidene)hydrazino)-2'-hydroxy-, Compound With 2-aminoethanol (1:2)

51. (1,1'-biphenyl)-3-carboxylic Acid, 3'-(2-(1-(3,4-dimethylphenyl)-4,5-dihydro-3-methyl-5-oxo-1h-pyrazol-4-yl)diazenyl)-2'-hydroxy-, Compd. With 2-aminoethanol (1:2)

52. 2-aminoethan-1-ol Hemi((z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate)

53. 2-aminoethanol (e)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1h-pyrazol-4(5h)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate

54. 2-aminoethanol;3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1h-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic Acid

55. 3'-[(2z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid Bis-(monoethanolamine)

56. 3'-[(2z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid Bis-(monoethanolamine)

57. 3'-{(2z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4h-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic Acid 2-aminoethanol (1:2)

2.4 Create Date
2019-01-15
3 Chemical and Physical Properties
Molecular Weight 564.6 g/mol
Molecular Formula C29H36N6O6
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count11
Rotatable Bond Count7
Exact Mass564.26963289 g/mol
Monoisotopic Mass564.26963289 g/mol
Topological Polar Surface Area207 Ų
Heavy Atom Count41
Formal Charge0
Complexity822
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Indication

Revolade is indicated for the treatment of adult patients with primary immune thrombocytopenia (ITP) who are refractory to other treatments (e. g. corticosteroids, immunoglobulins) (see sections 4. 2 and 5. 1).

Revolade is indicated for the treatment of paediatric patients aged 1 year and above with primary immune thrombocytopenia (ITP) lasting 6 months or longer from diagnosis and who are refractory to other treatments (e. g. corticosteroids, immunoglobulins) (see sections 4. 2 and 5. 1).

Revolade is indicated in adult patients with chronic hepatitis C virus (HCV) infection for the treatment of thrombocytopenia, where the degree of thrombocytopenia is the main factor preventing the initiation or limiting the ability to maintain optimal interferon-based therapy (see sections 4. 4 and 5. 1).

Revolade is indicated in adult patients with acquired severe aplastic anaemia (SAA) who were either refractory to prior immunosuppressive therapy or heavily pretreated and are unsuitable for haematopoietic stem cell transplantation (see section 5. 1).


5 Pharmacology and Biochemistry
5.1 FDA Pharmacological Classification
5.1.1 Pharmacological Classes
Increased Megakaryocyte Maturation [PE]; Increased Platelet Production [PE]; Organic Anion Transporting Polypeptide 1B1 Inhibitors [MoA]; Thrombopoietin Receptor Agonist [EPC]; Thrombopoietin Receptor Agonists [MoA]; UGT1A1 Inhibitors [MoA]; UGT1A3 Inhibitors [MoA]; UGT1A4 Inhibitors [MoA]; UGT1A6 Inhibitors [MoA]; UGT1A9 Inhibitors [MoA]; UGT2B15 Inhibitors [MoA]; UGT2B7 Inhibitors [MoA]; Breast Cancer Resistance Protein Inhibitors [MoA]
5.2 ATC Code

B02BX05


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MAHARASHTRA","supplier":"CHEMO","supplierCountry":"SPAIN","foreign_port":"MADRID","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1.20","actualQuantity":"1.2","unit":"KGS","unitRateFc":"9200","totalValueFC":"11163.2","currency":"USD","unitRateINR":"771880","date":"21-Feb-2024","totalValueINR":"926256","totalValueInUsd":"11163.2","indian_port":"Bombay Air","hs_no":"29147990","bill_no":"2236614","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Micronized","supplierPort":"MADRID","supplierAddress":"MANUEL POMBO ANGULO, 28, 3RD FLOOR28050 MADRID SPAIN Madrid, , SpainSDNF Spain","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718389800,"product":"(FOC) ELTROMBOPAG CHOLINE API","address":"21-22, KALPATARU SQUARE, KONDIVITA","city":"ANDHERI (E), MUMBAI,MAHARASHTRA","supplier":"ACTAVIS INC","supplierCountry":"CROATIA","foreign_port":"MIAMI, FL","customer":"TEVA PHARMACEUTICAL INDUSTRIES","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"10","unit":"GMS","unitRateFc":"76.5","totalValueFC":"927","currency":"USD","unitRateINR":"7738.7","date":"15-Jun-2024","totalValueINR":"77387.4","totalValueInUsd":"927","indian_port":"Bombay Air","hs_no":"29331930","bill_no":"4023891","productDescription":"API","marketType":"REGULATED MARKET","country":"CROATIA","selfForZScoreResived":"Pharma Grade","supplierPort":"MIAMI, FL","supplierAddress":"2945 WEST CORPORATE LAKES BLVD WESTON, FLORIDA 33331SDNF United States","customerAddress":"21-22, KALPATARU SQUARE, KONDIVITA"}]
21-Jan-2021
23-Oct-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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FDA Orange Book

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01

BioFlorida Conference
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ELTROMBOPAG

Brand Name : ELTROMBOPAG

Dosage Form : TABLET;ORAL

Dosage Strength : 50MG

Approval Date :

Application Number : 208815

RX/OTC/DISCN :

RLD :

TE Code :

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02

BioFlorida Conference
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ELTROMBOPAG OLAMINE

Brand Name : ELTROMBOPAG OLAMINE

Dosage Form : FOR SUSPENSION;ORAL

Dosage Strength : EQ 12.5MG ACID/PACKET

Approval Date : 2024-04-18

Application Number : 216620

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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03

BioFlorida Conference
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ELTROMBOPAG OLAMINE

Brand Name : ELTROMBOPAG OLAMINE

Dosage Form : FOR SUSPENSION;ORAL

Dosage Strength : EQ 25MG ACID/PACKET

Approval Date : 2024-04-18

Application Number : 216620

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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04

BioFlorida Conference
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ELTROMBOPAG CHOLINE

Brand Name : ALVAIZ

Dosage Form : TABLET;ORAL

Dosage Strength : EQ 9MG BASE

Approval Date : 2023-11-29

Application Number : 216774

RX/OTC/DISCN : RX

RLD : Yes

TE Code :

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05

NOVARTIS

Switzerland
BioFlorida Conference
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Switzerland
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BioFlorida Conference
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ELTROMBOPAG OLAMINE

Brand Name : PROMACTA

Dosage Form : TABLET;ORAL

Dosage Strength : EQ 25MG ACID

Approval Date : 2008-11-20

Application Number : 22291

RX/OTC/DISCN : RX

RLD : Yes

TE Code :

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06

NOVARTIS

Switzerland
BioFlorida Conference
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NOVARTIS

Switzerland
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BioFlorida Conference
Not Confirmed

ELTROMBOPAG OLAMINE

Brand Name : PROMACTA

Dosage Form : TABLET;ORAL

Dosage Strength : EQ 50MG ACID

Approval Date : 2008-11-20

Application Number : 22291

RX/OTC/DISCN : RX

RLD : Yes

TE Code :

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07

NOVARTIS

Switzerland
BioFlorida Conference
Not Confirmed
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NOVARTIS

Switzerland
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BioFlorida Conference
Not Confirmed

ELTROMBOPAG OLAMINE

Brand Name : PROMACTA

Dosage Form : TABLET;ORAL

Dosage Strength : EQ 75MG ACID

Approval Date : 2009-09-08

Application Number : 22291

RX/OTC/DISCN : RX

RLD : Yes

TE Code :

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08

NOVARTIS

Switzerland
BioFlorida Conference
Not Confirmed
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NOVARTIS

Switzerland
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BioFlorida Conference
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ELTROMBOPAG OLAMINE

Brand Name : PROMACTA KIT

Dosage Form : FOR SUSPENSION;ORAL

Dosage Strength : EQ 25MG ACID/PACKET

Approval Date : 2015-08-24

Application Number : 207027

RX/OTC/DISCN : RX

RLD : Yes

TE Code : AB

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09

NOVARTIS

Switzerland
BioFlorida Conference
Not Confirmed
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NOVARTIS

Switzerland
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BioFlorida Conference
Not Confirmed

ELTROMBOPAG OLAMINE

Brand Name : PROMACTA KIT

Dosage Form : FOR SUSPENSION;ORAL

Dosage Strength : EQ 12.5MG ACID/PACKET

Approval Date : 2018-09-27

Application Number : 207027

RX/OTC/DISCN : RX

RLD : Yes

TE Code : AB

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10

BioFlorida Conference
Not Confirmed
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BioFlorida Conference
Not Confirmed

ELTROMBOPAG

Brand Name : ELTROMBOPAG

Dosage Form : TABLET;ORAL

Dosage Strength : 12.5MG

Approval Date :

Application Number : 209938

RX/OTC/DISCN :

RLD :

TE Code :

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Europe

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01

  • fda
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  • WHO-GMP

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Flag Germany
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Regulatory Info : EU Dossier Readiness-Q2 2019

Registration Country : Germany

Eltrombopag

Brand Name :

Dosage Form : Film Coated Tablet

Dosage Strength : 12.5MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : EU Dossier Readiness-Q2 2019

Registration Country : Germany

Tiefenbacher Compnay Banner

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothWe are the TIEFENBACHER GROUP, Health Pioneers since 1963.

Flag Germany
Digital Content Digital Content

Regulatory Info : EU Dossier Readiness-Q2 2019

Registration Country : Germany

Eltrombopag

Brand Name :

Dosage Form : Film Coated Tablet

Dosage Strength : 25MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : EU Dossier Readiness-Q2 2019

Registration Country : Germany

Tiefenbacher Compnay Banner

03

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothWe are the TIEFENBACHER GROUP, Health Pioneers since 1963.

Flag Germany
Digital Content Digital Content

Regulatory Info : EU Dossier Readiness-Q2 2019

Registration Country : Germany

Eltrombopag

Brand Name :

Dosage Form : Film Coated Tablet

Dosage Strength : 50MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : EU Dossier Readiness-Q2 2019

Registration Country : Germany

Tiefenbacher Compnay Banner

04

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothWe are the TIEFENBACHER GROUP, Health Pioneers since 1963.

Flag Germany
Digital Content Digital Content

Regulatory Info : EU Dossier Readiness-Q2 2019

Registration Country : Germany

Eltrombopag

Brand Name :

Dosage Form : Film Coated Tablet

Dosage Strength : 75MG

Packaging :

Approval Date :

Application Number :

Regulatory Info : EU Dossier Readiness-Q2 2019

Registration Country : Germany

Tiefenbacher Compnay Banner

05

euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Eltrombopagum

Brand Name : Revolade

Dosage Form : Filmtable

Dosage Strength : 25mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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06

euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
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Eltrombopagum

Brand Name : Revolade

Dosage Form : Filmtable

Dosage Strength : 25mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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07

euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Eltrombopagum

Brand Name : Revolade

Dosage Form : Filmtable

Dosage Strength : 50mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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08

euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Eltrombopagum

Brand Name : Revolade

Dosage Form : Filmtable

Dosage Strength : 50mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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09

euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Eltrombopagum

Brand Name : Revolade

Dosage Form : Filmtabl

Dosage Strength : 75mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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10

euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
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Eltrombopagum

Brand Name : Revolade

Dosage Form : Filmtable

Dosage Strength : 12.5mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Switzerland

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Canada

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01

APOTEX INC

Canada
American Pharma Summit
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APOTEX INC

Canada
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Not Confirmed

ELTROMBOPAG (ELTROMBOPAG OLAMINE)

Brand Name : APO-ELTROMBOPAG

Dosage Form : TABLET

Dosage Strength : 25MG

Packaging :

Approval Date :

Application Number : 2506742

Regulatory Info : Prescription

Registration Country : Canada

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02

APOTEX INC

Canada
American Pharma Summit
Not Confirmed
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APOTEX INC

Canada
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American Pharma Summit
Not Confirmed

ELTROMBOPAG (ELTROMBOPAG OLAMINE)

Brand Name : APO-ELTROMBOPAG

Dosage Form : TABLET

Dosage Strength : 50MG

Packaging :

Approval Date :

Application Number : 2506769

Regulatory Info : Prescription

Registration Country : Canada

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03

American Pharma Summit
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American Pharma Summit
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ELTROMBOPAG (ELTROMBOPAG OLAMINE)

Brand Name : REVOLADE

Dosage Form : TABLET

Dosage Strength : 25MG

Packaging : 14/28

Approval Date :

Application Number : 2361825

Regulatory Info : Prescription

Registration Country : Canada

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04

American Pharma Summit
Not Confirmed
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American Pharma Summit
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ELTROMBOPAG (ELTROMBOPAG OLAMINE)

Brand Name : REVOLADE

Dosage Form : TABLET

Dosage Strength : 50MG

Packaging : 14/28

Approval Date :

Application Number : 2361833

Regulatory Info : Prescription

Registration Country : Canada

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - TABLET;ORAL - EQ 100MG ACID **Federa...DOSAGE - TABLET;ORAL - EQ 100MG ACID **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 22291

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DOSAGE - TABLET;ORAL - EQ 12.5MG ACID

USFDA APPLICATION NUMBER - 22291

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DOSAGE - TABLET;ORAL - EQ 25MG ACID

USFDA APPLICATION NUMBER - 22291

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DOSAGE - TABLET;ORAL - EQ 50MG ACID

USFDA APPLICATION NUMBER - 22291

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DOSAGE - TABLET;ORAL - EQ 75MG ACID

USFDA APPLICATION NUMBER - 22291

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Chewable & Orodispersible Aids

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Global Sales Information

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Market Place

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Patents & EXCLUSIVITIES

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US Patents

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01

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ELTROMBOPAG CHOLINE

US Patent Number : 11072586

Drug Substance Claim : Y

Drug Product Claim : Y

Application Number : 216774

Patent Use Code : U-3937

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2038-11-05

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02

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BioFlorida Conference
Not Confirmed
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BioFlorida Conference
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ELTROMBOPAG CHOLINE

US Patent Number : 11072586

Drug Substance Claim : Y

Drug Product Claim : Y

Application Number : 216774

Patent Use Code : U-3936

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2038-11-05

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03

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BioFlorida Conference
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NOVARTIS

Switzerland
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BioFlorida Conference
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ELTROMBOPAG OLAMINE

US Patent Number : 7547719

Drug Substance Claim : Y

Drug Product Claim : Y

Application Number : 22291

Patent Use Code : U-2451

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2025-07-13

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04

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BioFlorida Conference
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NOVARTIS

Switzerland
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BioFlorida Conference
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ELTROMBOPAG OLAMINE

US Patent Number : 8071129*PED

Drug Substance Claim :

Drug Product Claim :

Application Number : 22291

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2028-02-01

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05

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BioFlorida Conference
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NOVARTIS

Switzerland
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BioFlorida Conference
Not Confirmed

ELTROMBOPAG OLAMINE

US Patent Number : 8052994

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 22291

Patent Use Code : U-2451

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2027-08-01

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06

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BioFlorida Conference
Not Confirmed

NOVARTIS

Switzerland
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BioFlorida Conference
Not Confirmed

ELTROMBOPAG OLAMINE

US Patent Number : 8052994

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 22291

Patent Use Code : U-1714

Delist Requested :

Patent Use Description : TREATMENT OF THROMBOCY...

Patent Expiration Date : 2027-08-01

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07

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BioFlorida Conference
Not Confirmed

NOVARTIS

Switzerland
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BioFlorida Conference
Not Confirmed

ELTROMBOPAG OLAMINE

US Patent Number : 8062665*PED

Drug Substance Claim :

Drug Product Claim :

Application Number : 22291

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2028-02-01

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08

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BioFlorida Conference
Not Confirmed

NOVARTIS

Switzerland
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BioFlorida Conference
Not Confirmed

ELTROMBOPAG OLAMINE

US Patent Number : 8062665*PED

Drug Substance Claim :

Drug Product Claim :

Application Number : 22291

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2028-02-01

blank

09

arrow
BioFlorida Conference
Not Confirmed

NOVARTIS

Switzerland
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BioFlorida Conference
Not Confirmed

ELTROMBOPAG OLAMINE

US Patent Number : 8828430

Drug Substance Claim :

Drug Product Claim : Y

Application Number : 22291

Patent Use Code : U-2451

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2027-08-01

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10

arrow
BioFlorida Conference
Not Confirmed

NOVARTIS

Switzerland
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BioFlorida Conference
Not Confirmed

ELTROMBOPAG OLAMINE

US Patent Number : 8828430*PED

Drug Substance Claim :

Drug Product Claim :

Application Number : 22291

Patent Use Code :

Delist Requested :

Patent Use Description :

Patent Expiration Date : 2028-02-01

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US Exclusivities

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01

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euroPLX 86 Munich
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NOVARTIS

Switzerland
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euroPLX 86 Munich
Not Confirmed

ELTROMBOPAG OLAMINE

Exclusivity Code : ODE-210

Exclusivity Expiration Date : 2025-11-16

Application Number : 22291

Product Number : 1

Exclusivity Details :

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02

arrow
euroPLX 86 Munich
Not Confirmed

NOVARTIS

Switzerland
arrow
euroPLX 86 Munich
Not Confirmed

ELTROMBOPAG OLAMINE

Exclusivity Code : ODE-210

Exclusivity Expiration Date : 2025-11-16

Application Number : 22291

Product Number : 2

Exclusivity Details :

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03

arrow
euroPLX 86 Munich
Not Confirmed

NOVARTIS

Switzerland
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euroPLX 86 Munich
Not Confirmed

ELTROMBOPAG OLAMINE

Exclusivity Code : ODE-210

Exclusivity Expiration Date : 2025-11-16

Application Number : 22291

Product Number : 3

Exclusivity Details :

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04

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euroPLX 86 Munich
Not Confirmed

NOVARTIS

Switzerland
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euroPLX 86 Munich
Not Confirmed

ELTROMBOPAG OLAMINE

Exclusivity Code : ODE-210

Exclusivity Expiration Date : 2025-11-16

Application Number : 22291

Product Number : 4

Exclusivity Details :

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05

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euroPLX 86 Munich
Not Confirmed

NOVARTIS

Switzerland
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euroPLX 86 Munich
Not Confirmed

ELTROMBOPAG OLAMINE

Exclusivity Code : ODE-210

Exclusivity Expiration Date : 2025-11-16

Application Number : 22291

Product Number : 5

Exclusivity Details :

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06

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euroPLX 86 Munich
Not Confirmed

NOVARTIS

Switzerland
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euroPLX 86 Munich
Not Confirmed

ELTROMBOPAG OLAMINE

Exclusivity Code : ODE*

Exclusivity Expiration Date : 2025-11-16

Application Number : 207027

Product Number : 1

Exclusivity Details :

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07

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euroPLX 86 Munich
Not Confirmed

NOVARTIS

Switzerland
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euroPLX 86 Munich
Not Confirmed

ELTROMBOPAG OLAMINE

Exclusivity Code : ODE*

Exclusivity Expiration Date : 2025-11-16

Application Number : 207027

Product Number : 2

Exclusivity Details :

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Health Canada Patents

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01

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euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Eltrombopag

Brand Name : REVOLADE

Patent Number : 2486697

Filing Date : 2003-05-21

Strength per Unit : 25 mg

Dosage Form : Tablet

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2023-05-21

Date Granted : 2009-01-06

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02

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euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Eltrombopag

Brand Name : REVOLADE

Patent Number : 2411468

Filing Date : 2001-05-24

Strength per Unit : 25 mg

Dosage Form : Tablet

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2021-05-24

Date Granted : 2008-04-15

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03

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euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Eltrombopag

Brand Name : REVOLADE

Patent Number : 2685831

Filing Date : 2007-08-01

Strength per Unit : 25 mg

Dosage Form : Tablet

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2027-08-01

Date Granted : 2013-11-26

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04

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euroPLX 86 Munich
Not Confirmed
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euroPLX 86 Munich
Not Confirmed

Eltrombopag

Brand Name : REVOLADE

Patent Number : 2486697

Filing Date : 2003-05-21

Strength per Unit : 50 mg

Dosage Form : Tablet

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2023-05-21

Date Granted : 2009-01-06

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05

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euroPLX 86 Munich
Not Confirmed
arrow
euroPLX 86 Munich
Not Confirmed

Eltrombopag

Brand Name : REVOLADE

Patent Number : 2411468

Filing Date : 2001-05-24

Strength per Unit : 50 mg

Dosage Form : Tablet

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2021-05-24

Date Granted : 2008-04-15

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06

arrow
euroPLX 86 Munich
Not Confirmed
arrow
euroPLX 86 Munich
Not Confirmed

Eltrombopag

Brand Name : REVOLADE

Patent Number : 2685831

Filing Date : 2007-08-01

Strength per Unit : 50 mg

Dosage Form : Tablet

Human Or VET : Human

Route of Administration : Oral

Patent Expiration Date : 2027-08-01

Date Granted : 2013-11-26

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07

arrow
euroPLX 86 Munich
Not Confirmed
arrow
euroPLX 86 Munich
Not Confirmed

Eltrombopag

Brand Name : REVOLADE

Patent Number : 2685831

Filing Date : 2007-08-01

Strength per Unit : 75 mg

Dosage Form : TABLET

Human Or VET : Human

Route of Administration : ORAL

Patent Expiration Date : 2027-08-01

Date Granted : 2013-11-06

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08

arrow
euroPLX 86 Munich
Not Confirmed
arrow
euroPLX 86 Munich
Not Confirmed

Eltrombopag

Brand Name : REVOLADE

Patent Number : 2411468

Filing Date : 2001-05-24

Strength per Unit : 75 mg

Dosage Form : TABLET

Human Or VET : Human

Route of Administration : ORAL

Patent Expiration Date : 2021-05-24

Date Granted : 2008-04-15

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09

arrow
euroPLX 86 Munich
Not Confirmed
arrow
euroPLX 86 Munich
Not Confirmed

Eltrombopag

Brand Name : REVOLADE

Patent Number : 2486697

Filing Date : 2003-05-21

Strength per Unit : 75 mg

Dosage Form : TABLET

Human Or VET : Human

Route of Administration : ORAL

Patent Expiration Date : 2023-05-21

Date Granted : 2009-01-06

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