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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

API REF. PRICE (USD/KG)

MARKET PLACE

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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US Patents

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Health Canada Patents

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Data Compilation #PharmaFlow

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Stock Recap #PipelineProspector

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News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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Finished Drug Prices

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0RELATED EXCIPIENT COMPANIES

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Chemistry

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Also known as: 155030-63-0, Emodepside [inn], Bay-44-4400, Bay 44-4400, Yz647y5gc9, Chebi:78739
Molecular Formula
C60H90N6O14
Molecular Weight
1119.4  g/mol
InChI Key
ZMQMTKVVAMWKNY-YSXLEBCMSA-N
FDA UNII
YZ647Y5GC9

Emodepside
Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the octadepsipeptides, a relatively new class of anthelmintic.
1 2D Structure

Emodepside

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(3S,6R,9S,12R,15S,18R,21S,24R)-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone
2.1.2 InChI
InChI=1S/C60H90N6O14/c1-37(2)31-47-57(71)77-41(9)53(67)61(11)50(34-40(7)8)60(74)80-52(36-44-17-21-46(22-18-44)66-25-29-76-30-26-66)56(70)64(14)48(32-38(3)4)58(72)78-42(10)54(68)62(12)49(33-39(5)6)59(73)79-51(55(69)63(47)13)35-43-15-19-45(20-16-43)65-23-27-75-28-24-65/h15-22,37-42,47-52H,23-36H2,1-14H3/t41-,42-,47+,48+,49+,50+,51-,52-/m1/s1
2.1.3 InChI Key
ZMQMTKVVAMWKNY-YSXLEBCMSA-N
2.1.4 Canonical SMILES
CC1C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)O1)CC(C)C)C)CC2=CC=C(C=C2)N3CCOCC3)CC(C)C)C)C)CC(C)C)C)CC4=CC=C(C=C4)N5CCOCC5)CC(C)C)C
2.1.5 Isomeric SMILES
C[C@@H]1C(=O)N([C@H](C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N([C@H](C(=O)O1)CC(C)C)C)CC2=CC=C(C=C2)N3CCOCC3)CC(C)C)C)C)CC(C)C)C)CC4=CC=C(C=C4)N5CCOCC5)CC(C)C)C
2.2 Other Identifiers
2.2.1 UNII
YZ647Y5GC9
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 155030-63-0

2. Emodepside [inn]

3. Bay-44-4400

4. Bay 44-4400

5. Yz647y5gc9

6. Chebi:78739

7. Pf-1022-221

8. (3s,6r,9s,12r,15s,18r,21s,24r)-3,9,15,21-tetraisobutyl-4,6,10,16,18,22-hexamethyl-12,24-bis(4-morpholinobenzyl)-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosan-2,5,8,11,14,17,20,23-octaone

9. Pf 1022-221

10. (3s,6r,9s,12r,15s,18r,21s,24r)-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone

11. Cyclo((r)-lactoyl-n-methyl-l-leucyl-(r)-3-(p-morpholinophenyl)lactoyl-n-methyl-l-leucyl-(r)-lactoyl-n-methyl-l-leucyl-(r)-3-(p-morpholinophenyl)lactoyl-n-methyl-l-leucyl)

12. (3~{s},6~{r},9~{s},12~{r},15~{s},18~{r},21~{s},24~{r})-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone

13. Emodepsida

14. Emodepsidum

15. Unii-yz647y5gc9

16. Cyclo[(r)-lactoyl-n-methyl-l-leucyl-(r)-3-(p-morpholinophenyl)lactoyl-n-methyl-l-leucyl-(r)-lactoyl-n-methyl-l-leucyl-(r)-3-(p-morpholinophenyl)lactoyl-n-methyl-l-leucyl]

17. Emodepside [mi]

18. Schembl167580

19. Emodepside [green Book]

20. Chembl2104404

21. Dtxsid50165799

22. Procox Component Emodepside

23. Profender Component Emodepside

24. Emodepside Component Of Procox

25. Db11403

26. Emodepside [ema Epar Veterinary]

27. Emodepside Component Of Profender

28. Ncgc00507682-01

29. Ac-31930

30. C18390

31. E74446

32. A929940

33. Q1339032

34. (3s,6r,9s,12r,15s,18r,21s,24r)-3,9,15,21-tetraisobutyl-4,6,10,16,18,22-hexamethyl-12,24-bis[4-(morpholin-4-yl)benzyl]-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane-2,5,8,11,14,17,20,23-octone

35. 4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone

36. 8i2

37. Cyclo [d-2-hydroxypropanoyl-n-methyl-l-leucyl-3-[4-(4-morpholinyl)phenyl]-d-2-hydroxypropanoyl-n-methyl-l-leucyl-d-2-hydroxypropanoyl-n-methyl-l-leucyl-3-[4-(4-morpholinyl)phenyl]-d-2-hydroxypropanoyl-n-methyl-l-leucyl]

38. Cyclo {d-lactoyl-n-methyl-l-leucyl-3-[4-(4-morpholinyl)phenyl]-d-lactoyl-n-methyl-l-leucyl-d-lactoyl-n-methyl-l-leucyl-3-[4-(4-morpholinyl)phenyl]-d-lactoyl-n-methyl-l-leucyl}

39. Cyclo((.alpha.r)-.alpha.-hydroxy-4-(4-morpholinyl)benzenepropanoyl-n-methyl-l-leucyl-(2r)-2-hydroxypropanoyl-n-methyl-l-leucyl-(.alpha.r)-.alpha.-hydroxy-4-(4-morpholinyl)benzenepropanoyl-n-methyl-l-leucyl-(2r)-2-hydroxypropanoyl-n-methyl-l-leucyl)

2.4 Create Date
2006-07-28
3 Chemical and Physical Properties
Molecular Weight 1119.4 g/mol
Molecular Formula C60H90N6O14
XLogP39
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count16
Rotatable Bond Count14
Exact Mass1118.65150157 g/mol
Monoisotopic Mass1118.65150157 g/mol
Topological Polar Surface Area211 Ų
Heavy Atom Count80
Formal Charge0
Complexity1900
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antiparasitic Agents

Drugs used to treat or prevent parasitic infections. (See all compounds classified as Antiparasitic Agents.)


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ABOUT THIS PAGE

Emodepside Manufacturers

A Emodepside manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Emodepside, including repackagers and relabelers. The FDA regulates Emodepside manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Emodepside API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Emodepside manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Emodepside Suppliers

A Emodepside supplier is an individual or a company that provides Emodepside active pharmaceutical ingredient (API) or Emodepside finished formulations upon request. The Emodepside suppliers may include Emodepside API manufacturers, exporters, distributors and traders.

click here to find a list of Emodepside suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Emodepside GMP

Emodepside Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Emodepside GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Emodepside GMP manufacturer or Emodepside GMP API supplier for your needs.

Emodepside CoA

A Emodepside CoA (Certificate of Analysis) is a formal document that attests to Emodepside's compliance with Emodepside specifications and serves as a tool for batch-level quality control.

Emodepside CoA mostly includes findings from lab analyses of a specific batch. For each Emodepside CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Emodepside may be tested according to a variety of international standards, such as European Pharmacopoeia (Emodepside EP), Emodepside JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Emodepside USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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