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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

13 API Suppliers, 2 USDMF, 1 EU WC, 6 KDMF, 1 NDC API, 10 Listed Suppliers, $ API Reference Price

13 API Suppliers
2 USDMF
1 EU WC
6 KDMF
1 NDC API
10 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

26 Drugs in Development

26 Drugs in Development

INTERMEDIATES

2 Intermediates Suppliers

2 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

16 FDF Dossiers, 3 FDA Orange Book, 7 Europe, 3 South Africa, 3 Listed Dossiers

16 FDF Dossiers
3 FDA Orange Book
7 Europe
3 South Africa
3 Listed Dossiers

DIGITAL CONTENT

2 DATA COMPILATION #PharmaFlow, 2 STOCK RECAP #PipelineProspector, 74 NEWS #PharmaBuzz

media
2 DATA COMPILATION #PharmaFlow
2 STOCK RECAP #PipelineProspector
74 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

7 Finished Drug Prices, 24 Annual Reports

globalSalesInformation
7 Finished Drug Prices
24 Annual Reports

MARKET PLACE

5 APIs, 2 FDF Dossiers

marketPlace
5 APIs
2 FDF Dossiers

ANALYTICAL

1 BioAnalytical Methods

otherMethods
1 BioAnalytical Methods

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

67,938

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Schembl16402708

Molecular Formula

C₂₁H₂₉N₆O₅P

Molecular Weight

476.5 g/mol

InChI Key

LDEKQSIMHVQZJK-LYTUVDLCSA-N

1 2D Structure

Tenofovir Alafenamide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

propan-2-yl (2S)-2-[[1-(6-aminopurin-9-yl)propan-2-yloxymethyl-phenoxyphosphoryl]amino]propanoate

2.1.2 InChI

InChI=1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)/t15?,16-,33+/m0/s1

2.1.3 InChI Key

LDEKQSIMHVQZJK-LYTUVDLCSA-N

2.1.4 Canonical SMILES

CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3

2.1.5 Isomeric SMILES

C[C@@H](C(=O)OC(C)C)N[P@@](=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Schembl16402708

2.3 Create Date

2013-04-19

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₂₉N₆O₅P
Molecular Weight	476.5 g/mol
XLogP3	1.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	12
Exact Mass	476.19370504 g/mol
Monoisotopic Mass	476.19370504 g/mol
Topological Polar Surface Area	144 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	680
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

API SUPPLIERS

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USDMF

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EU WC

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KDMF

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NDC API

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Listed Suppliers

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API Reference Price

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","customerCountry":"THAILAND","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"1473.8","totalValueFC":"4348.5","currency":"USD","unitRateINR":105524.66666666667,"date":"19-Mar-2021","totalValueINR":"316574","totalValueInUsd":"4348.5","indian_port":"Vizag-RPCIPL SEZ","hs_no":"29335990","bill_no":"4000307","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"THAILAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Vizag-RPCIPL SEZ","supplierAddress":"564\/A\/22, ROAD NO.92, HYDERABAD,ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1637519400,"product":"TENOFOVIR ALAFENAMIDE FUMARATE(BATCH NO;","address":"N0 116\/117, KIADB INDUSTRIAL AREA,JIGANI","city":"BANGALORE","supplier":"CDYMAX (INDIA) PHARMA PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES, BA","customer":"M\/S.LABORATORIOS RICHMOND,","customerCountry":"ARGENTINA","quantity":"4.00","actualQuantity":"4","unit":"KGS","unitRateFc":"4000","totalValueFC":"15334.8","currency":"USD","unitRateINR":285500,"date":"22-Nov-2021","totalValueINR":"1142000","totalValueInUsd":"15334.8","indian_port":"BANGALORE AIR","hs_no":"29420090","bill_no":"6171964","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGALORE AIR","supplierAddress":"N0 116\/117, KIADB INDUSTRIAL AREA,JIGANI, BANGALORE","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1639679400,"product":"TENOFOVIR ALAFENAMIDE FUMARATE (OTHER RE","address":"NATCO HOUSE, ROAD NO.2,,BANJARA H ILLS,","city":"HYDERABAD,TELANGANA","supplier":"NATCO PHARMA","supplierCountry":"INDIA","foreign_port":"HO CHI MINH C","customer":"BRV HEALTHCARE COMPANY ","customerCountry":"VIETNAM","quantity":"18.00","actualQuantity":"18","unit":"KGS","unitRateFc":"3100","totalValueFC":"55630.6","currency":"USD","unitRateINR":233111.11111111112,"date":"17-Dec-2021","totalValueINR":"4196000","totalValueInUsd":"55630.6","indian_port":"HYDERABAD AIR","hs_no":"29309099","bill_no":"6817929","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"VIETNAM, DEMOCRATIC REP. OF","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"NATCO HOUSE, ROAD NO.2,,BANJARA H ILLS,, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1645036200,"product":"TENOFOVIR ALAFENAMIDE FUMARATE BATCH NO;","address":"N0 116\/117, KIADB INDUSTRIAL AREA, ,JIGANI 2ND PHASE","city":"BANGALORE,KARNATAKA","supplier":"CDYMAX (INDIA) PHARMA PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES, BA","customer":"THE CONSIGNEE","customerCountry":"ARGENTINA","quantity":"7.00","actualQuantity":"7","unit":"KGS","unitRateFc":"4000","totalValueFC":"27002.2","currency":"USD","unitRateINR":289142.85714285716,"date":"17-Feb-2022","totalValueINR":"2024000","totalValueInUsd":"27002.2","indian_port":"BANGALORE AIR","hs_no":"29335990","bill_no":"8289043","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGALORE AIR","supplierAddress":"N0 116\/117, KIADB INDUSTRIAL AREA, ,JIGANI 2ND PHASE, BANGALORE,KARNATAKA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1657218600,"product":"TENOFOVIR ALAFENAMIDE FUMARATE BATCH NO;","address":"N0 116\/117, KIADB INDUSTRIAL AREA, ,JIGANI 2ND PHASE","city":"BANGALORE,KARNATAKA","supplier":"CDYMAX (INDIA) PHARMA PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES, BA","customer":"THE CONSIGNEE","customerCountry":"ARGENTINA","quantity":"7.00","actualQuantity":"7","unit":"KGS","unitRateFc":"3800","totalValueFC":"25290.3","currency":"USD","unitRateINR":287285.71428571426,"date":"08-Jul-2022","totalValueINR":"2011000","totalValueInUsd":"25290.3","indian_port":"BANGALORE AIR","hs_no":"29335990","bill_no":"2684362","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGALORE AIR","supplierAddress":"N0 116\/117, KIADB INDUSTRIAL AREA, ,JIGANI 2ND PHASE, BANGALORE,KARNATAKA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1664994600,"product":"TENOFOVIR ALAFENAMIDE HEMI FUMARATE BATC","address":"N0 116\/117, KIADB INDUSTRIAL AREA, ,JIGANI 2ND PHASE","city":"BANGALORE,KARNATAKA","supplier":"CDYMAX (INDIA) PHARMA PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"EVA PHARMA","customerCountry":"EGYPT","quantity":"7.50","actualQuantity":"7.5","unit":"KGS","unitRateFc":"3650","totalValueFC":"25703.6","currency":"USD","unitRateINR":282000,"date":"06-Oct-2022","totalValueINR":"2115000","totalValueInUsd":"25703.6","indian_port":"BANGALORE AIR","hs_no":"29420090","bill_no":"4641188","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGALORE AIR","supplierAddress":"N0 116\/117, KIADB INDUSTRIAL AREA, ,JIGANI 2ND PHASE, BANGALORE,KARNATAKA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1668018600,"product":"TENOFOVIR ALAFENAMIDE FUMARATE IP","address":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. 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