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Encainide

Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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ACTIVE PHARMA INGREDIENTS

2 API Suppliers, 2 USDMF

2 API Suppliers
2 USDMF

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: 66794-74-9, Encainide hcl, Enkaid, Encainide (hydrochloride), Encainide hydrochloride [usan], Mj 9067-1

Molecular Formula

C₂₂H₂₉ClN₂O₂

Molecular Weight

388.9 g/mol

InChI Key

OJIIZIWOLTYOBS-UHFFFAOYSA-N

FDA UNII

4CH7J36N9S

One of the ANTI-ARRHYTHMIA AGENTS, it blocks VOLTAGE-GATED SODIUM CHANNELS and slows conduction within the His-Purkinje system and MYOCARDIUM.

1 2D Structure

Encainide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-methoxy-N-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]benzamide;hydrochloride

2.1.2 InChI

InChI=1S/C22H28N2O2.ClH/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18;/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25);1H

2.1.3 InChI Key

OJIIZIWOLTYOBS-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN1CCCCC1CCC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)OC.Cl

2.2 Other Identifiers

2.2.1 UNII

4CH7J36N9S

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Encainide

2. Encainide Hydrochloride, (+-)-isomer

3. Encainide, (+)-isomer

4. Encainide, (-)-isomer

5. Enkaid

6. Mj 9067

7. Mj-9067

8. Mj9067

2.3.2 Depositor-Supplied Synonyms

1. 66794-74-9

2. Encainide Hcl

3. Enkaid

4. Encainide (hydrochloride)

5. Encainide Hydrochloride [usan]

6. Mj 9067-1

7. Mj-9067

8. Encainidehydrochloride

9. 4-methoxy-2'-(2-(1-methyl-2-piperidyl)ethyl)benzanilide Hydrochloride

10. (+-)-2'-(2-(1-methyl-2-piperidyl)ethyl)-p-anisanilide Monohydrochloride

11. 4ch7j36n9s

12. Chebi:59880

13. 4-methoxy-n-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]benzamide;hydrochloride

14. (+/-)-4-methoxy-n-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]benzamide Hydrochloride

15. Mj-9067-1

16. Encainide Hydrochloride (usan)

17. 2-(2-{2-[(4-methoxybenzoyl)amino]phenyl}ethyl)-1-methylpiperidinium Chloride

18. 4-methoxy-n-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide Hydrochloride

19. Enkade; Enkaid;benzamide, 4-methoxy-n-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]-, Monohydrochloride (9ci); Benzamide, 4-methoxy-n-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]-, Monohydrochloride, (+/-)-

20. Ncgc00185765-01

21. Unii-4ch7j36n9s

22. Mfcd01667688

23. Dsstox_cid_28930

24. Dsstox_rid_83196

25. Dsstox_gsid_49004

26. Mls004712064

27. Schembl121261

28. Chembl2106155

29. Dtxsid2049004

30. Encainide Hydrochloride [mi]

31. Tox21_113498

32. Nsc299238

33. Akos025311581

34. Encainide Hydrochloride [mart.]

35. Encainide Hydrochloride [vandf]

36. Nsc-299238

37. Encainide Hydrochloride [who-dd]

38. Benzamide, 4-methoxy-n-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)-, Monohydrochloride, (+-)-

39. Hy-12531

40. Smr002529683

41. Cas-66794-74-9

42. Cs-0011988

43. D03991

44. H11012

45. Encainide Hydrochloride, >=98% (hplc), Powder

46. Q27126935

47. 4-methoxy-2' -[2-(1-methyl- 2-piperidyl)athyl]benzanilid-hydrochlorid

48. (+/-)-2'-(2-(1-methyl-2-piperidyl)ethyl)-p-anisanilide Monohydrochloride

49. Benzamide, 4-methoxy-n-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)-, Monohydrochloride, (+/-)-

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₂₉ClN₂O₂
Molecular Weight	388.9 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	6
Exact Mass	388.1917559 g/mol
Monoisotopic Mass	388.1917559 g/mol
Topological Polar Surface Area	41.6 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	434
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Arrhythmia Agents

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

Voltage-Gated Sodium Channel Blockers

A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS. (See all compounds classified as Voltage-Gated Sodium Channel Blockers.)

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ABOUT THIS PAGE

Encainide Manufacturers

A Encainide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Encainide, including repackagers and relabelers. The FDA regulates Encainide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Encainide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Encainide Suppliers

A Encainide supplier is an individual or a company that provides Encainide active pharmaceutical ingredient (API) or Encainide finished formulations upon request. The Encainide suppliers may include Encainide API manufacturers, exporters, distributors and traders.

click here to find a list of Encainide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Encainide USDMF

A Encainide DMF (Drug Master File) is a document detailing the whole manufacturing process of Encainide active pharmaceutical ingredient (API) in detail. Different forms of Encainide DMFs exist exist since differing nations have different regulations, such as Encainide USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Encainide DMF submitted to regulatory agencies in the US is known as a USDMF. Encainide USDMF includes data on Encainide's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Encainide USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Encainide suppliers with USDMF on PharmaCompass.

Encainide GMP

Encainide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Encainide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Encainide GMP manufacturer or Encainide GMP API supplier for your needs.

Encainide CoA

A Encainide CoA (Certificate of Analysis) is a formal document that attests to Encainide's compliance with Encainide specifications and serves as a tool for batch-level quality control.

Encainide CoA mostly includes findings from lab analyses of a specific batch. For each Encainide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Encainide may be tested according to a variety of international standards, such as European Pharmacopoeia (Encainide EP), Encainide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Encainide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.