Please Wait
Applying Filters...
menu
    • menu
    Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.

    Virtual Booth

    Contact Supplier

    AbbVie CDMO has been working with global companies to develop, manufacture & scale biopharmaceutical products.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

    Virtual Booth

    Contact Supplier

    ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    Menu

    Encainide

    ACTIVE PHARMA INGREDIENTS

    PharmaCompass
    Xls

    Filters

    clear-filterReset all filters
    2D Structure
    Also known as: 66794-74-9, Encainide hcl, Enkaid, Encainide (hydrochloride), Encainide hydrochloride [usan], Mj 9067-1
    Molecular Formula
    C22H29ClN2O2
    Molecular Weight
    388.9  g/mol
    InChI Key
    OJIIZIWOLTYOBS-UHFFFAOYSA-N
    FDA UNII
    4CH7J36N9S
    One of the ANTI-ARRHYTHMIA AGENTS, it blocks VOLTAGE-GATED SODIUM CHANNELS and slows conduction within the His-Purkinje system and MYOCARDIUM.
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-methoxy-N-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]benzamide;hydrochloride
    2.1.2 InChI
    InChI=1S/C22H28N2O2.ClH/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18;/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25);1H
    2.1.3 InChI Key
    OJIIZIWOLTYOBS-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CN1CCCCC1CCC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)OC.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    4CH7J36N9S
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Encainide

    2. Encainide Hydrochloride, (+-)-isomer

    3. Encainide, (+)-isomer

    4. Encainide, (-)-isomer

    5. Enkaid

    6. Mj 9067

    7. Mj-9067

    8. Mj9067

    2.3.2 Depositor-Supplied Synonyms

    1. 66794-74-9

    2. Encainide Hcl

    3. Enkaid

    4. Encainide (hydrochloride)

    5. Encainide Hydrochloride [usan]

    6. Mj 9067-1

    7. Mj-9067

    8. Encainidehydrochloride

    9. 4-methoxy-2'-(2-(1-methyl-2-piperidyl)ethyl)benzanilide Hydrochloride

    10. (+-)-2'-(2-(1-methyl-2-piperidyl)ethyl)-p-anisanilide Monohydrochloride

    11. 4ch7j36n9s

    12. Chebi:59880

    13. 4-methoxy-n-[2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl]benzamide;hydrochloride

    14. (+/-)-4-methoxy-n-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]benzamide Hydrochloride

    15. Mj-9067-1

    16. Encainide Hydrochloride (usan)

    17. 2-(2-{2-[(4-methoxybenzoyl)amino]phenyl}ethyl)-1-methylpiperidinium Chloride

    18. 4-methoxy-n-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide Hydrochloride

    19. Enkade; Enkaid;benzamide, 4-methoxy-n-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]-, Monohydrochloride (9ci); Benzamide, 4-methoxy-n-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]-, Monohydrochloride, (+/-)-

    20. Ncgc00185765-01

    21. Unii-4ch7j36n9s

    22. Mfcd01667688

    23. Dsstox_cid_28930

    24. Dsstox_rid_83196

    25. Dsstox_gsid_49004

    26. Mls004712064

    27. Schembl121261

    28. Chembl2106155

    29. Dtxsid2049004

    30. Encainide Hydrochloride [mi]

    31. Tox21_113498

    32. Nsc299238

    33. Akos025311581

    34. Encainide Hydrochloride [mart.]

    35. Encainide Hydrochloride [vandf]

    36. Nsc-299238

    37. Encainide Hydrochloride [who-dd]

    38. Benzamide, 4-methoxy-n-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)-, Monohydrochloride, (+-)-

    39. Hy-12531

    40. Smr002529683

    41. Cas-66794-74-9

    42. Cs-0011988

    43. D03991

    44. H11012

    45. Encainide Hydrochloride, >=98% (hplc), Powder

    46. Q27126935

    47. 4-methoxy-2' -[2-(1-methyl- 2-piperidyl)athyl]benzanilid-hydrochlorid

    48. (+/-)-2'-(2-(1-methyl-2-piperidyl)ethyl)-p-anisanilide Monohydrochloride

    49. Benzamide, 4-methoxy-n-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)-, Monohydrochloride, (+/-)-

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 388.9 g/mol
    Molecular Formula C22H29ClN2O2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count3
    Rotatable Bond Count6
    Exact Mass388.1917559 g/mol
    Monoisotopic Mass388.1917559 g/mol
    Topological Polar Surface Area41.6 Ų
    Heavy Atom Count27
    Formal Charge0
    Complexity434
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Anti-Arrhythmia Agents

    Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)

    Voltage-Gated Sodium Channel Blockers

    A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS. (See all compounds classified as Voltage-Gated Sodium Channel Blockers.)