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1. 5 Methionine Enkephalin
2. 5-methionine Enkephalin
3. Enkephalin, 5-methionine
4. Enkephalin, Methionine
5. Met Enkephalin
6. Met(5)-enkephalin
7. Methionine Enkephalin
1. 58569-55-4
2. Methionine Enkephalin
3. H-tyr-gly-gly-phe-met-oh
4. Tyr-gly-gly-phe-met-oh
5. Tyr-gly-gly-phe-met
6. [met]enkephalin
7. [5-methionine]enkephalin
8. (met5)-enkephalin
9. Opioid Growth Factor
10. Metenkefalin [inn]
11. Metenkefalin
12. 9jez9od3as
13. Chembl13786
14. Enkephalin, Methionine
15. (2s)-2-[[(2s)-2-[[2-[[2-[[(2s)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic Acid
16. [met5]-enkephalin
17. [met5]enkephalin Acetate Salt Hydrate
18. (2s)-2-[[(2s)-2-[[2-[[2-[[(2s)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenyl-propanoyl]amino]-4-methylsulfanyl-butanoic Acid
19. Opioid Growth Factor (ogf)
20. 82362-17-2
21. Unii-9jez9od3as
22. Chebi:6618
23. Porcine Beta-endorphin 1-5
24. Met-enkefalin
25. Ccris 4225
26. Met5-enkephalin
27. Np2 Enkephalin
28. Nsc-374896
29. [met]-enkephalin
30. Met-enk
31. 1-5 Adrenorphin
32. 2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic Acid
33. Einecs 261-335-8
34. Sh-pentapeptide-19
35. Nsc 374896
36. Inno-105
37. L-methionine, L-tyrosylglycylglycyl-l-phenylalanyl-
38. 1-5-adrenorphin (human)
39. Enkephalin-(5-l-methionine)
40. Metenkefalin [who-dd]
41. Schembl632433
42. Gtpl1614
43. Dtxsid80332078
44. Irt-101
45. Hy-p0073
46. Sh-pentapeptide-19 [inci]
47. Zinc4102171
48. Bdbm50019056
49. Mfcd00076415
50. Cs-5426
51. Db12668
52. Ncgc00163683-01
53. As-58159
54. C75740
55. 569t554
56. A915141
57. Met-enkephalin (h-l-tyr-gly-gly-l-phe-l-met-oh)
58. N-(n-(n-(n-l-tyrosylglycyl)glycyl)-l-phenylalanyl)-l-methionine
59. Adrenorphin (human), 6-de-l-arginine-7-de-l-arginine-8-de-l-valinamide-
60. ([met]-enkephalin)2-[2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric Acid([met]-enkephalin
61. (s)-2-[(s)-2-(2-{2-[(s)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric Acid
62. 2-[(s)-2-(2-{2-[(s)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methylsulfanyl-butyric Acid
63. 2-[1-[1-amino-2-(4-hydroxyphenyl)-(1s)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1s)-ethylcarboxamido]-4-methylsulfanyl-(2s)-butanoic Acid
64. 2-[2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric Acid
65. L-tyrosylglycylglycyl-l-phenylalanyl-l-methionine .beta.-endorphin Human-(1-5)-peptide
Molecular Weight | 573.7 g/mol |
---|---|
Molecular Formula | C27H35N5O7S |
XLogP3 | -2.1 |
Hydrogen Bond Donor Count | 7 |
Hydrogen Bond Acceptor Count | 9 |
Rotatable Bond Count | 16 |
Exact Mass | 573.22571965 g/mol |
Monoisotopic Mass | 573.22571965 g/mol |
Topological Polar Surface Area | 225 Ų |
Heavy Atom Count | 40 |
Formal Charge | 0 |
Complexity | 847 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 3 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Metenkefalin is indicated in Bosnia for the treatment of relapsing-remitting multiple sclerosis.
Neurotransmitter Agents
Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. (See all compounds classified as Neurotransmitter Agents.)
Absorption
Metenkefalin reaches a Cmax of 1266.14pg/mL, with a Tmax of 0.16h, and an AUC of 360.64pg\*h/mL.
The half life of metenkefalin is 4.2-39 minutes.
Metenkefalin is an agonist of and opioid receptors. It also causes immunostimulation at low doses and immunosuppression at higher doses. Metenkefalin can also inhibit the production of aldosterone, deoxycorticosterone, and corticosterone. Unfortuneately, the mechanisms by which these effects occur have not been well described in the literature.