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Chemistry

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Also known as: Ostarine, 841205-47-8, Gtx-024, Mk-2866, Enobosarm [usan], Mk-2866 (gtx-024)
Molecular Formula
C19H14F3N3O3
Molecular Weight
389.3  g/mol
InChI Key
JNGVJMBLXIUVRD-SFHVURJKSA-N
FDA UNII
O3571H3R8N

Enobosarm
Enobosarm is a non-steroidal agent with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, thus promoting and/or maintaining libido, fertility, prostate growth, and muscle growth and strength. Mimicking testosterone's action, this agent may increase lean body mass, thereby ameliorating muscle wasting in the hypermetabolic state of cancer cachexia.
1 2D Structure

Enobosarm

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
2.1.2 InChI
InChI=1S/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m0/s1
2.1.3 InChI Key
JNGVJMBLXIUVRD-SFHVURJKSA-N
2.1.4 Canonical SMILES
CC(COC1=CC=C(C=C1)C#N)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
2.1.5 Isomeric SMILES
C[C@](COC1=CC=C(C=C1)C#N)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
2.2 Other Identifiers
2.2.1 UNII
O3571H3R8N
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (2s)-3-(4-cyanophenoxy)-n-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide

2. Gtx 024

3. Gtx-024

4. Mk 2866

5. Mk-2866

6. Mk2866

7. Ostarine

2.3.2 Depositor-Supplied Synonyms

1. Ostarine

2. 841205-47-8

3. Gtx-024

4. Mk-2866

5. Enobosarm [usan]

6. Mk-2866 (gtx-024)

7. 1202044-20-9

8. Ostarine (mk2866)

9. Ostarine(mk-2866)

10. (2s)-3-(4-cyanophenoxy)-n-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

11. (s)-n-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide

12. Mk 2866

13. O3571h3r8n

14. Enobosarm (usan)

15. Propanamide, 3-(4-cyanophenoxy)-n-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methyl-, (2s)-

16. Mk2866

17. ((2s)-3-(4-cyanophenoxy)-n-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide)

18. Enobosarm [usan:inn]

19. Gtx 024

20. Unii-o3571h3r8n

21. Ostarine-d4

22. (s)-ostarine

23. (2s)-3-(4-cyanophenoxy)-n-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide

24. Enobosarm [inn]

25. Ostarine(mk-2286)

26. Enobosarm [who-dd]

27. Mls006010739

28. Sarm S-22

29. Schembl109069

30. Not For Sale-patented"

31. Chembl1738889

32. Dtxsid30233006

33. Ex-a638

34. Hms3654e16

35. Amy38131

36. Bcp02391

37. Bcp28483

38. Bdbm50529668

39. S1174

40. Zinc35793636

41. Akos005266718

42. Ccg-268514

43. Cs-0562

44. Db12078

45. Ex-8408

46. Sb16683

47. Ncgc00346499-01

48. Ac-30221

49. Hy-13273

50. Smr004701698

51. Sw219159-1

52. Ostarine(mk2286); 1202044-20-9

53. D10221

54. H12015

55. A864177

56. Q5379258

57. 1235370-13-4

58. Mk-2866(d4);mk2866(d4);gtx-024(d4);gtx024;(s)-n-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide-d4

59. Mk-2866; Gtx024;((2s)-3-(4-cyanophenoxy)-n-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide)

60. Propanamide, 3-?(4-?cyanophenoxy)?-?n-?[4-?cyano-?3-?(trifluoromethyl)?phenyl]?-?2-?hydroxy-?2-?methyl-?, (2s)?-

61. Rlj

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 389.3 g/mol
Molecular Formula C19H14F3N3O3
XLogP32.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass389.09872580 g/mol
Monoisotopic Mass389.09872580 g/mol
Topological Polar Surface Area106 Ų
Heavy Atom Count28
Formal Charge0
Complexity658
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Enobosarm Manufacturers

A Enobosarm manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Enobosarm, including repackagers and relabelers. The FDA regulates Enobosarm manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Enobosarm API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Enobosarm Suppliers

A Enobosarm supplier is an individual or a company that provides Enobosarm active pharmaceutical ingredient (API) or Enobosarm finished formulations upon request. The Enobosarm suppliers may include Enobosarm API manufacturers, exporters, distributors and traders.

Enobosarm NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Enobosarm as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Enobosarm API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Enobosarm as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Enobosarm and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Enobosarm NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Enobosarm suppliers with NDC on PharmaCompass.

Enobosarm GMP

Enobosarm Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Enobosarm GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Enobosarm GMP manufacturer or Enobosarm GMP API supplier for your needs.

Enobosarm CoA

A Enobosarm CoA (Certificate of Analysis) is a formal document that attests to Enobosarm's compliance with Enobosarm specifications and serves as a tool for batch-level quality control.

Enobosarm CoA mostly includes findings from lab analyses of a specific batch. For each Enobosarm CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Enobosarm may be tested according to a variety of international standards, such as European Pharmacopoeia (Enobosarm EP), Enobosarm JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Enobosarm USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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