Find Enprostil manufacturers, exporters & distributors on PharmaCompass

Enprostil

Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 USDMF

1 API Suppliers
1 USDMF

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 73121-56-9, Camleed, Gardrin, Rs-84135, Rs 84135-004, Gardrine

Molecular Formula

C₂₃H₂₈O₆

Molecular Weight

400.5 g/mol

InChI Key

PTOJVMZPWPAXER-VFJVYMGBSA-N

A synthetic PGE2 analog that has an inhibitory effect on gastric acid secretion, a mucoprotective effect, and a postprandial lowering effect on gastrin. It has been shown to be efficient and safe in the treatment of gastroduodenal ulcers.

1 2D Structure

Enprostil

2 Identification

2.1 Computed Descriptors

2.1.1 InChI

InChI=1S/C23H28O6/c1-28-23(27)12-8-3-2-7-11-19-20(22(26)15-21(19)25)14-13-17(24)16-29-18-9-5-4-6-10-18/h3-7,9-10,13-14,17,19-20,22,24,26H,8,11-12,15-16H2,1H3/b14-13+/t2?,17-,19-,20-,22-/m1/s1

2.1.2 InChI Key

PTOJVMZPWPAXER-VFJVYMGBSA-N

2.1.3 Canonical SMILES

COC(=O)CCC=C=CCC1C(C(CC1=O)O)C=CC(COC2=CC=CC=C2)O

2.1.4 Isomeric SMILES

COC(=O)CCC=C=CC[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](COC2=CC=CC=C2)O

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Enprostil, (1alpha(r*),2beta(1e,3r*),3alpha)-(+-)-isomer

2. Enprostil, (1alpha(r*),2beta(1e,3s*),3alpha)-(+-)-isomer

3. Enprostil, (1alpha,2alpha(1e,3s*),3beta)-(+-)-isomer

4. Enprostil, (1alpha,2beta(1e,3r*),3alpha)-(+-)-isomer

5. Enprostil, (1r-(1(r*),2beta(1e,3r*),3alpha))-isomer

6. Enprostil, (1r-(1alpha(s*),2beta(1e,3r*),3alpha))-isomer

7. Enprostil, (1r-(1alpha,2beta(1e,3r*),3alpha))-isomer

8. Enprostil, (1s-(1alpha(r*),2beta(1e,3r*),3alpha))-isomer

9. Enprostil, (1s-(1alpha(s*),2beta(1e,3r*),3alpha))-isomer

10. Gardrin

11. Rs 84135

12. Rs-84135

13. Rs84135

2.2.2 Depositor-Supplied Synonyms

1. 73121-56-9

2. Camleed

3. Gardrin

4. Rs-84135

5. Rs 84135-004

6. Gardrine

7. Syngard

8. Enprostil (jan/usan/inn)

9. Camleed (tn)

10. Rs-86505-007

11. Schembl186877

12. Gtpl1918

13. Chembl2104194

14. Dtxsid401021647

15. Ex-a6212

16. Zinc3812898

17. Akos016014109

18. D01891

19. Methyl 7-[(1r,2r,3r)-3-hydroxy-2-[(e,3r)-3-hydroxy-4-(phenoxy)but-1-enyl]-5-oxocyclopentyl]hepta-4,5-dienoate

2.3 Create Date

2005-12-16

3 Chemical and Physical Properties

Molecular Formula	C₂₃H₂₈O₆
Molecular Weight	400.5 g/mol
XLogP3	1.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	11
Exact Mass	400.18858861 g/mol
Monoisotopic Mass	400.18858861 g/mol
Topological Polar Surface Area	93.1 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	613
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Ulcer Agents

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief. (See all compounds classified as Anti-Ulcer Agents.)

4.2 ATC Code

A - Alimentary tract and metabolism

A02 - Drugs for acid related disorders

A02B - Drugs for peptic ulcer and gastro-oesophageal reflux disease (gord)

A02BB - Prostaglandins

A02BB02 - Enprostil

API SUPPLIERS