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1. 2-phenylbenzimidazole-5-sulfonic Acid
2. 2-phenylbenzimidazole-5-sulfonic Acid, Monosodium Salt
3. Eusolex 232
4. Novantisol
5. Phenylbenzimidazole Sulfonic Acid
6. Phenylbenzimidazole Sulphonic Acid
1. 27503-81-7
2. 2-phenylbenzimidazole-5-sulfonic Acid
3. Phenylbenzimidazole Sulfonic Acid
4. 2-phenyl-1h-benzo[d]imidazole-5-sulfonic Acid
5. 2-phenyl-5-benzimidazolesulfonic Acid
6. 1h-benzimidazole-5-sulfonic Acid, 2-phenyl-
7. 2-phenyl-1h-benzo[d]imidazole-6-sulfonic Acid
8. 2-phenyl-1h-benzimidazole-5-sulfonic Acid
9. 2-phenyl-3h-benzimidazole-5-sulfonic Acid
10. Parsol Hs
11. 2-phenyl-1h-benzimidazole-5-sulphonic Acid
12. 9yq9di1w42
13. 1h-benzimidazole-6-sulfonic Acid, 2-phenyl-
14. Ncgc00166262-01
15. 1h-benzimidazole-5-sulfonic Acid-2-phenyl-
16. Dsstox_cid_18852
17. Dsstox_rid_79408
18. Dsstox_gsid_38852
19. Ensulizole [inn]
20. Cas-27503-81-7
21. Ultraviolet Absorbent Uv-t
22. Unii-9yq9di1w42
23. Ensulizole [usan:usp:inn]
24. Einecs 248-502-0
25. 2-phenylbenzimidazole-5-sulfonicacid
26. Mfcd00053007
27. Pbsa
28. Ensulizole [mi]
29. Ensulizole (usp/inn)
30. Ensulizole [usan]
31. Ec 248-502-0
32. Ensulizole [mart.]
33. Ensulizole [usp-rs]
34. Ensulizole [who-dd]
35. Schembl16277
36. Phenylbenzimidazole-sulfonic-acid
37. Chembl1987518
38. Dtxsid3038852
39. Chebi:135132
40. Bdbm181124
41. Ensulizole [usp Monograph]
42. Bcp17614
43. Zinc6467621
44. Tox21_112381
45. Tox21_200995
46. Bbl028055
47. S4419
48. Stk034479
49. 2-phenylbenzimidazole-5-sulphonic Acid
50. Akos005381771
51. Akos006029164
52. Parsol Hs 100 Microg/ml In Methanol
53. Tox21_112381_1
54. Us9138393, 2-phenyl Benzimidazole
55. Us9144538, 2-phenyl Benzimidazole
56. Ccg-245160
57. Db11115
58. 2-phenylbenz-imidazole-5-sulphonic Acid
59. Ncgc00166262-02
60. Ncgc00166262-03
61. Ncgc00258548-01
62. Ac-11988
63. As-12559
64. 2-phenylbenzo[d]imidazole-5-sulfonic Acid
65. Db-021496
66. Hy-109654
67. 2-phenyl-3h-benzimidazol-1-ium-5-sulfonate
68. 2-phenyl-5-benzimidazolesulfonic Acid, 96%
69. Cs-0033783
70. Ft-0613323
71. P1670
72. 2-phenyl-1h-1,3-benzodiazole-6-sulfonic Acid
73. D10005
74. H11816
75. Phenylbenzimidazole Sulfonic Acid [inci]
76. Ab00090049-01
77. 503p817
78. A819096
79. Sr-01000883690
80. Q-200317
81. Q7181424
82. Sr-01000883690-1
83. 2-phenylbenzimidazole-5-sulfonic Acid [vandf]
84. Us9138393, 2-phenyl-5- Benzimidazole Sulfonic Acid
85. Z275232302
86. Ensulizole, United States Pharmacopeia (usp) Reference Standard
87. 2-phenyl-5-benzimidazolesulfonic Acid, Analytical Reference Material
88. 2-phenyl-7ah-benzimidazole-5-sulfonic Acid;2-phenylbenzimidazole-5-sulfonic Acid
89. Ensulizole(2-phenylbenzimidazole 5-sulfonic Acid), Pharmaceutical Secondary Standard; Certified Reference Material
Molecular Weight | 274.30 g/mol |
---|---|
Molecular Formula | C13H10N2O3S |
XLogP3 | 2 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 2 |
Exact Mass | 274.04121336 g/mol |
Monoisotopic Mass | 274.04121336 g/mol |
Topological Polar Surface Area | 91.4 Ų |
Heavy Atom Count | 19 |
Formal Charge | 0 |
Complexity | 414 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Indicated to be used as an UV-B-absorbing molecule in sunscreen formulations.
Ensulizole is a selective UV-B filter with little activity against UV-A wavelengths. _In vitro_, ensulizole oxidizes guanine bases upon photoexcitation by UV-B and may cause photodamage on DNA, proteins and lipids in the cellular context.
Ensulizole strongly absorbs UV-B wavelengths. It offers protection against UV-B-induced cyclobutane pyrimidine dimers. Based on the findings in vitro and in cellulo, ensulizole induces damage on the DNA, causes DNA strand breaks and photosensitizes the formation of oxidized guanines via type I and II photosensitization mechanisms following UV-A or UV-B irradiation. Ensulizole is capable of generating reactive oxygen species, including singlet oxygen upon photoexcitation.