Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

DEVELOPMENTS

2 Drugs in Development

2 Drugs in Development

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

2DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Enzomenib [inn], Vw83y2jlz5, Chembl5314915, Schembl21782940, Us10815241, example 6, Bdbm470581

Molecular Formula

C₃₃H₄₃FN₆O₃

Molecular Weight

590.7 g/mol

InChI Key

JQHJEDMMWUIYCE-FVVBACEJSA-N

FDA UNII

VW83Y2JLZ5

DSP-5336 is a menin inhibitor.

1 2D Structure

Enzomenib

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

5-fluoro-2-[4-[7-[(1S,3S,4R)-5-methylidene-2-azabicyclo[2.2.2]octane-3-carbonyl]-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl]oxy-N,N-di(propan-2-yl)benzamide

2.1.2 InChI

InChI=1S/C33H43FN6O3/c1-20(2)40(21(3)4)31(41)26-15-23(34)6-9-27(26)43-28-16-35-19-36-30(28)39-17-33(18-39)10-12-38(13-11-33)32(42)29-25-8-7-24(37-29)14-22(25)5/h6,9,15-16,19-21,24-25,29,37H,5,7-8,10-14,17-18H2,1-4H3/t24-,25+,29-/m0/s1

2.1.3 InChI Key

JQHJEDMMWUIYCE-FVVBACEJSA-N

2.1.4 Canonical SMILES

CC(C)N(C(C)C)C(=O)C1=C(C=CC(=C1)F)OC2=CN=CN=C2N3CC4(C3)CCN(CC4)C(=O)C5C6CCC(N5)CC6=C

2.1.5 Isomeric SMILES

CC(C)N(C(C)C)C(=O)C1=C(C=CC(=C1)F)OC2=CN=CN=C2N3CC4(C3)CCN(CC4)C(=O)[C@@H]5[C@@H]6CC[C@H](N5)CC6=C

2.2 Other Identifiers

2.2.1 UNII

VW83Y2JLZ5

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. Enzomenib [inn]

2. Vw83y2jlz5

3. Chembl5314915

4. Schembl21782940

5. Us10815241, Example 6

6. Bdbm470581

7. Dsp-5336

8. 2412555-70-3

9. 5-fluoro-2-[(4-{7-[(1s,3s,4r)-5-methylidene-2-azabicyclo[2.2.2]octane-3-carbonyl]-2,7-diazaspiro[3.5]nonan-2-yl}pyrimidin-5-yl)oxy]-n,n-di(propan-2-yl)benzamide

10. 5-fluoro-2-[[4-[7-[[(1s,3s,4r)-5-methylene-2-azabicyclo[2.2.2]oct-3-yl]carbonyl]-2,7-diazaspiro[3.5]non-2-yl]-5-pyrimidinyl]oxy]-n,n-bis(1-methylethyl)benzamide

11. Benzamide, 5-fluoro-2-((4-(7-(((1s,3s,4r)-5-methylene-2-azabicyclo(2.2.2)oct-3-yl)carbonyl)-2,7-diazaspiro(3.5)non-2-yl)-5-pyrimidinyl)oxy)-n,n-bis(1-methylethyl)-

2.4 Create Date

2020-06-27

3 Chemical and Physical Properties

Molecular Formula	C₃₃H₄₃FN₆O₃
Molecular Weight	590.7 g/mol
XLogP3	4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	7
Exact Mass	g/mol
Monoisotopic Mass	g/mol
Topological Polar Surface Area	90.9
Heavy Atom Count	43
Formal Charge	0
Complexity	1030
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1