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ACTIVE PHARMA INGREDIENTS

15 API Suppliers, 12 USDMF, 1 EU WC, 7 NDC API, 6 Listed Suppliers, $ API Reference Price

15 API Suppliers
12 USDMF
1 EU WC
7 NDC API
6 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

6 Drugs in Development

6 Drugs in Development

FINISHED DOSAGE FORMULATIONS

26 FDF Dossiers, 21 FDA Orange Book, 1 Canada, 2 South Africa, 2 Listed Dossiers

26 FDF Dossiers
21 FDA Orange Book
1 Canada
2 South Africa
2 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

SOLUTION;INTRAVENOUS - 25MG/5ML (5MG/ML), SOLUTION;INTRAVENOUS - 50MG/ML (50MG/ML)

drugProductComposition
SOLUTION;INTRAVENOUS - 25MG/5ML (5MG/ML)
SOLUTION;INTRAVENOUS - 50MG/ML (50MG/ML)

RELATED EXCIPIENT COMPANIES

1 Rochem International Inc, 5 SPI Pharma, 2 Seqens, 7 DKSH, 5 Faran Shimi Pharmaceutical, 1 Boai NKY Pharmaceuticals Ltd, 11 Gangwal Healthcare, 4 ACG Worldwide, 6 Actylis, 1 Aeon Procare, 7 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 20 BASF, 10 Corel Pharma Chem, 3 DFE Pharma, 1 Finar, 8 Gangwal Chemicals, 7 Ideal Cures Pvt Ltd, 3 Ingredion Pharma Solutions, 17 Kerry, 3 Kima Chemical, 6 Lonza Capsugel, 11 Microlex e.U, 2 Nomisma Healthcare, 3 Novo Excipients, 2 Pharmatrans-Sanaq, 5 Pluviaendo, 3 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 2 Qualicaps, 23 Roquette, 7 Seppic, 5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 10 Sigachi Industries, 2 The Dow Chemical Company, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

55 Fillers, Diluents & Binders, 52 Coating Systems & Additives, 31 Controlled & Modified Release, 27 Direct Compression, 25 Thickeners and Stabilizers, 21 Disintegrants & Superdisintegrants, 18 Granulation, 16 Lubricants & Glidants, 13 Solubilizers, 12 Co-Processed Excipients, 10 Film Formers & Plasticizers, 10 Taste Masking, 9 Empty Capsules, 9 Topical, 7 Chewable & Orodispersible Aids, 7 Parenteral, 5 API Stability Enhancers, 4 Vegetarian Capsules, 4 Coloring Agents, 4 Emulsifying Agents, 3 Rheology Modifiers

DIGITAL CONTENT

2 DATA COMPILATION #PharmaFlow, 32 NEWS #PharmaBuzz

media
2 DATA COMPILATION #PharmaFlow
32 NEWS #PharmaBuzz

MARKET PLACE

2 APIs, 2 FDF Dossiers

marketPlace
2 APIs
2 FDF Dossiers

PATENTS & EXCLUSIVITIES

10 US Patents

patents
10 US Patents

REF. STANDARDS & IMPURITIES

1 USP , 1 Others

otherSolutions
1 USP
1 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 68

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

6DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

207 RELATED EXCIPIENT COMPANIES

342EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Ephedrine sulphate, Isofedrol, Akovaz, 134-72-5, Corphedra, Ephedrine sulfate [usp]

Molecular Formula

C₂₀H₃₂N₂O₆S

Molecular Weight

428.5 g/mol

InChI Key

CAVQBDOACNULDN-KHFUBBAMSA-N

FDA UNII

U6X61U5ZEG

A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.

1 2D Structure

Ephedrine Sulfate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(1R,2S)-2-(methylamino)-1-phenylpropan-1-ol;sulfuric acid

2.1.2 InChI

InChI=1S/2C10H15NO.H2O4S/c2*1-8(11-2)10(12)9-6-4-3-5-7-9;1-5(2,3)4/h2*3-8,10-12H,1-2H3;(H2,1,2,3,4)/t2*8-,10-;/m00./s1

2.1.3 InChI Key

CAVQBDOACNULDN-KHFUBBAMSA-N

2.1.4 Canonical SMILES

CC(C(C1=CC=CC=C1)O)NC.CC(C(C1=CC=CC=C1)O)NC.OS(=O)(=O)O

2.1.5 Isomeric SMILES

C[C@@H]([C@@H](C1=CC=CC=C1)O)NC.C[C@@H]([C@@H](C1=CC=CC=C1)O)NC.OS(=O)(=O)O

2.2 Other Identifiers

2.2.1 UNII

U6X61U5ZEG

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Ephedrine

2. Ephedrine Erythro Isomer

3. Ephedrine Hydrochloride

4. Ephedrine Renaudin

5. Erythro Isomer Of Ephedrine

6. Hydrochloride, Ephedrine

7. Renaudin, Ephedrine

8. Sal Phedrine

9. Sal-phedrine

10. Salphedrine

11. Sulfate, Ephedrine

2.3.2 Depositor-Supplied Synonyms

1. Ephedrine Sulphate

2. Isofedrol

3. Akovaz

4. 134-72-5

5. Corphedra

6. Ephedrine Sulfate [usp]

7. U6x61u5zeg

8. (-)-ephedrine Sulfate (2:1) (salt)

9. 134-72-5 (sulfate)

10. (-)-ephedrine Hemisulfate

11. Nci-c55652

12. Ephedrine Sulfate (usp)

13. Benzenemethanol, Alpha-((1s)-1-(methylamino)ethyl)-, (alphar)-, Sulfate (2:1) (salt)

14. (1r,2s)-2-(methylamino)-1-phenylpropan-1-ol;sulfuric Acid

15. L-ephedrine Sulfate

16. Unii-u6x61u5zeg

17. Expansyl

18. Ccris 1351

19. Ephedrini Sulfas

20. Pazo Ointment

21. Franol Plus

22. Franol-plus

23. (1r,2s)-2-(methylamino)-1-phenylpropan-1-ol Sulfate (2:1) (salt)

24. Pazo Suppositories

25. Corphedra (tn)

26. Emerphed (tn)

27. Einecs 205-154-4

28. Akovaz (tn)

29. Emerphed

30. Ephedrine L- Sulfate

31. 1-phenyl-2-methylamine-propanol-1-sulfate

32. Ec 205-154-4

33. Schembl41262

34. (1r,2s)-1-phenyl-2-methylaminopropanol-1 Sulfate

35. Ephedrine Sulfate [mi]

36. 1-alpha-(1-(methylamino)ethyl)benzyl Alcohol Sulfate

37. Chembl1523964

38. Dtxsid6020565

39. Ephedrine Sulfate [vandf]

40. Ephedrine Sulfate [mart.]

41. Ephedrine Sulfate [usp-rs]

42. Ephedrine Sulfate [who-dd]

43. Ephedrine Sulfate [who-ip]

44. (-)-erythro-1-hydroxy-2-(methylamino)-1-phenylpropane Sulfate

45. Bdbm50480314

46. Akos015901652

47. Ephedrine Sulfate [orange Book]

48. Ephedrini Sulfas [who-ip Latin]

49. Ephedrine Sulfate [usp Monograph]

50. Ncgc00093901-01

51. Ephedrine Sulfate (2:1) (salt), (-)-

52. Eu-0100501

53. D04018

54. E 3250

55. Q27290771

56. Ephedrine Sulphate 1.0 Mg/ml In Methanol (as Free Base)

57. Bis((r-(r*,s*))-beta-hydroxy-alpha-methylphenethyl)methylammonium Sulphate

58. Bis((r-(r*,s*))-beta-hydroxy-alpha-methylphenethyl)methylammonium) Sulphate

59. Benzenemethanol, Alpha-((1s)-1-(methylamino)ethyl)-, (alphar)-, Sulfate (2:1)

60. Benzenemethanol, Alpha-(1-(methylamino)ethyl)-, (r-(r*,s*))-, Sulfate (2:1) (salt)

61. Benzenemethanol, Alpha-(1-(methylamino)ethyl)-, (theta-(theta,s))-, Sulfate (2:1) (salt)

62. (r-(r*,s*))-.alpha.-(1-(methylamino)ethyl)benzenemethanol Sulfate (2:1) (salt) [who-ip]

63. Benzenemethanol, .alpha.-(1-(methylamino)ethyl)-, (r-(r*,s*))-, Sulfate (2:1) (salt)

2.4 Create Date

2005-07-19

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₃₂N₂O₆S
Molecular Weight	428.5 g/mol
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	6
Exact Mass	428.19810792 g/mol
Monoisotopic Mass	428.19810792 g/mol
Topological Polar Surface Area	148 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	202
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Adrenergic Agents

Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters. (See all compounds classified as Adrenergic Agents.)

Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

Vasoconstrictor Agents

Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)

Central Nervous System Stimulants

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)

4.2 FDA Pharmacological Classification

4.2.1 Pharmacological Classes

Adrenergic beta-Agonists [MoA]; Increased Norepinephrine Activity [PE]; Norepinephrine Releasing Agent [EPC]; alpha-Adrenergic Agonist [EPC]; beta-Adrenergic Agonist [EPC]; Adrenergic alpha-Agonists [MoA]

API SUPPLIERS

01

Malladi Drugs & Pharmaceuticals Li...

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

PharmaVenue

Not Confirmed

Malladi is a leader in Ephedrine, Pseudoephedrine Salts & Phenylephrine HCl // USFDA, EDQM, ANSM, KFDA, and TGA inspected.

Contact Supplier

India

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USDMF

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CEP/COS JDMF EU-WC NDC

KDMF VMF Others AUDIT

02

Pharm-RX Chemical

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

PharmaVenue

Not Confirmed

Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

Corporate PDF

03

Nortec Quimica

Brazil

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

PharmaVenue

Not Confirmed

Nortec Quimica is the largest API manufacturer in Latin America.

Contact Supplier

Brazil

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

04

Embio Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

PharmaVenue

Not Confirmed

05

Siegfried AG

Switzerland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

PharmaVenue

Not Confirmed

06

Siegfried AG

Switzerland

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

PharmaVenue

Not Confirmed

07

elm-plastic GmbH

Germany

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

PharmaVenue

Not Confirmed

08

Catalytica

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

PharmaVenue

Not Confirmed

09

Avon Organics Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

PharmaVenue

Not Confirmed

10

Krebs Biochemicals & Industries Lt...

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

PharmaVenue

Not Confirmed

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API Reference Price

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Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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DOSAGE - SOLUTION;INTRAVENOUS - 25MG/5ML (5MG...DOSAGE - SOLUTION;INTRAVENOUS - 25MG/5ML (5MG/ML)

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ABOUT THIS PAGE

Ephedrine Sulfate Manufacturers

A Ephedrine Sulfate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ephedrine Sulfate, including repackagers and relabelers. The FDA regulates Ephedrine Sulfate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ephedrine Sulfate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ephedrine Sulfate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ephedrine Sulfate Suppliers

A Ephedrine Sulfate supplier is an individual or a company that provides Ephedrine Sulfate active pharmaceutical ingredient (API) or Ephedrine Sulfate finished formulations upon request. The Ephedrine Sulfate suppliers may include Ephedrine Sulfate API manufacturers, exporters, distributors and traders.

click here to find a list of Ephedrine Sulfate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ephedrine Sulfate USDMF

A Ephedrine Sulfate DMF (Drug Master File) is a document detailing the whole manufacturing process of Ephedrine Sulfate active pharmaceutical ingredient (API) in detail. Different forms of Ephedrine Sulfate DMFs exist exist since differing nations have different regulations, such as Ephedrine Sulfate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Ephedrine Sulfate DMF submitted to regulatory agencies in the US is known as a USDMF. Ephedrine Sulfate USDMF includes data on Ephedrine Sulfate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ephedrine Sulfate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Ephedrine Sulfate suppliers with USDMF on PharmaCompass.

Ephedrine Sulfate WC

A Ephedrine Sulfate written confirmation (Ephedrine Sulfate WC) is an official document issued by a regulatory agency to a Ephedrine Sulfate manufacturer, verifying that the manufacturing facility of a Ephedrine Sulfate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Ephedrine Sulfate APIs or Ephedrine Sulfate finished pharmaceutical products to another nation, regulatory agencies frequently require a Ephedrine Sulfate WC (written confirmation) as part of the regulatory process.

click here to find a list of Ephedrine Sulfate suppliers with Written Confirmation (WC) on PharmaCompass.

Ephedrine Sulfate NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Ephedrine Sulfate as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Ephedrine Sulfate API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Ephedrine Sulfate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Ephedrine Sulfate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Ephedrine Sulfate NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Ephedrine Sulfate suppliers with NDC on PharmaCompass.

Ephedrine Sulfate GMP

Ephedrine Sulfate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ephedrine Sulfate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ephedrine Sulfate GMP manufacturer or Ephedrine Sulfate GMP API supplier for your needs.

Ephedrine Sulfate CoA

A Ephedrine Sulfate CoA (Certificate of Analysis) is a formal document that attests to Ephedrine Sulfate's compliance with Ephedrine Sulfate specifications and serves as a tool for batch-level quality control.

Ephedrine Sulfate CoA mostly includes findings from lab analyses of a specific batch. For each Ephedrine Sulfate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ephedrine Sulfate may be tested according to a variety of international standards, such as European Pharmacopoeia (Ephedrine Sulfate EP), Ephedrine Sulfate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ephedrine Sulfate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

15 API Suppliers

12 USDMF

1 EU WC

7 NDC API

6 Listed Suppliers

$ API Reference Price

DEVELOPMENTS

6 Drugs in Development

FINISHED DOSAGE FORMULATIONS

26 FDF Dossiers

21 FDA Orange Book

1 Canada

2 South Africa

2 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

SOLUTION;INTRAVENOUS - 25MG/5ML (5MG/ML)

SOLUTION;INTRAVENOUS - 50MG/ML (50MG/ML)

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EXCIPIENTS BY APPLICATIONS

55 Fillers, Diluents & Binders

52 Coating Systems & Additives

31 Controlled & Modified Release

27 Direct Compression

25 Thickeners and Stabilizers

21 Disintegrants & Superdisintegrants

18 Granulation

16 Lubricants & Glidants

13 Solubilizers

12 Co-Processed Excipients

10 Film Formers & Plasticizers

10 Taste Masking

9 Empty Capsules

9 Topical

7 Chewable & Orodispersible Aids

7 Parenteral

5 API Stability Enhancers

4 Vegetarian Capsules

4 Coloring Agents

4 Emulsifying Agents