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Also known as: 144143-96-4, Teveten, Eprosartan mesilate, Eprosartan methanesulfonate, Eprosartan monomethanesulfonate, Eprosartan (mesylate)
Molecular Formula
C24H28N2O7S2
Molecular Weight
520.6  g/mol
InChI Key
DJSLTDBPKHORNY-XMMWENQYSA-N
FDA UNII
8N2L1NX8S3

Eprosartan Mesylate
Eprosartan Mesylate is the mesylate salt form of eprosartan, a non-biphenyl, non-tetrazole, nonpeptide angiotensin II antagonist with antihypertensive activity. Eprosartan mesylate antagonizes angiotensin II type I receptors in tissues such as vascular smooth muscle and the adrenal gland. This prevents angiotensin II-induced vasoconstriction and prevents angiotensin II-mediated stimulation of aldosterone secretion by the adrenal cortex, which decreases the excretion of sodium and water and increases the excretion of potassium.
1 2D Structure

Eprosartan Mesylate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[[2-butyl-5-[(E)-2-carboxy-3-thiophen-2-ylprop-1-enyl]imidazol-1-yl]methyl]benzoic acid;methanesulfonic acid
2.1.2 InChI
InChI=1S/C23H24N2O4S.CH4O3S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27;1-5(2,3)4/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H,28,29);1H3,(H,2,3,4)/b18-12+;
2.1.3 InChI Key
DJSLTDBPKHORNY-XMMWENQYSA-N
2.1.4 Canonical SMILES
CCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)C=C(CC3=CC=CS3)C(=O)O.CS(=O)(=O)O
2.1.5 Isomeric SMILES
CCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)/C=C(\CC3=CC=CS3)/C(=O)O.CS(=O)(=O)O
2.2 Other Identifiers
2.2.1 UNII
8N2L1NX8S3
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-thiophenepropanoic Acid, Alpha-((2-butyl-1-((4- Carboxyphenyl)methyl)-lh-imidazol-5-yl)methylene)-, (e)-

2. Eprosartan

3. Sk And F 108566

4. Skf-108566

5. Teveten

2.3.2 Depositor-Supplied Synonyms

1. 144143-96-4

2. Teveten

3. Eprosartan Mesilate

4. Eprosartan Methanesulfonate

5. Eprosartan Monomethanesulfonate

6. Eprosartan (mesylate)

7. Sk&f 108566-j

8. Sk&f-108566-j

9. 8n2l1nx8s3

10. Chebi:48409

11. (e)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimidazole-5-acrylic Acid, Monomethanesulfonate

12. 4-[[2-butyl-5-[(e)-2-carboxy-3-thiophen-2-ylprop-1-enyl]imidazol-1-yl]methyl]benzoic Acid;methanesulfonic Acid

13. Eprosartan Mesylate (usan)

14. Dsstox_cid_24217

15. Dsstox_rid_80124

16. Dsstox_gsid_44217

17. Eprosartan Mesylate [usan]

18. 4-({2-butyl-5-[(1e)-2-carboxy-2-(thiophen-2-ylmethyl)eth-1-en-1-yl]-1h-imidazol-1-yl}methyl)benzoic Acid; Methanesulfonic Acid

19. Cas-144143-96-4

20. Eprosartan Mesylate [usan:ban]

21. Ncgc00164557-01

22. Unii-8n2l1nx8s3

23. Futuran

24. Navixen

25. Regulaten

26. Tevetenz

27. Epro-sartan Mesylate Dihydrate

28. Sr-05000001450

29. Eprosartanmesylate

30. Teveten Sb

31. Skf-108566j

32. Teveten (tn)

33. Schembl41396

34. Chembl1200987

35. Dtxsid7044217

36. Hms3262b17

37. Hms3885b05

38. Eprosartan Mesylate [vandf]

39. Eprosartan Mesilate [mart.]

40. Tox21_112186

41. Tox21_500808

42. Eprosartan Mesilate [who-dd]

43. Eprosartan Mesylate [usp-rs]

44. Hy-15834a

45. Mfcd08141807

46. S4102

47. Akos015994738

48. Eprosartan Mesylate, >=98% (hplc)

49. Tox21_112186_1

50. Am84399

51. Ccg-222112

52. Ks-1233

53. Eprosartan Mesylate [orange Book]

54. Ncgc00167505-02

55. Ncgc00261493-01

56. (e)-4-((2-butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1h-imidazol-1-yl)methyl)benzoic Acid Compound With Methanesulfonic Acid (1:1)

57. 2-thiophenepropanoic Acid, Alpha-((2-butyl-1-((4-carboxyphenyl)methyl)-1h-imidazol-5-yl)methylene)-, (e)-, Monomethanesulfonate

58. Eprosartan Mesylate [usp Monograph]

59. Eprosartan Monomethanesulfonate [mi]

60. E-145

61. E1161

62. Sw219286-1

63. A13747

64. D02082

65. Teveten Hct Component Eprosartan Mesylate

66. 143e964

67. A808180

68. Eprosartan Mesylate Component Of Teveten Hct

69. J-007923

70. Sr-05000001450-2

71. Q27121190

72. Eprosartan Mesylate, United States Pharmacopeia (usp) Reference Standard

73. (e)-2-butyl-1-(p-carboxybenzyl)-.alpha.-2-thenylimidazole-5-acrylic Acid, Monomethanesulfonate

74. (e)-2-butyl-1-(p-carboxybenzyl)-.alpha.-2-thenylimidazole-5-acrylic Acid, Monomethanesulphonate

75. (e)-4-((2-butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1h-imidazol-1-yl)methyl)benzoic Acid Methanesulfonic Acid Salt

76. (e)-alpha-((2-butyl-1-((4-carboxyphenyl)methyl)-1h-imidazol-5-yl)methylene)-2-thiophenepropanoic Acid Monomethanesulfonate

77. 2-thiophenepropanoic Acid, .alpha.-((2-butyl-1-((4-carboxyphenyl)methyl)-1h-imidazol-5-yl)methylene)-, (e)-, Monomethanesulfonate

78. 2-thiophenepropanoic Acid, .alpha.-((2-butyl-1-((4-carboxyphenyl)methyl)-1h-imidazol-5-yl)methylene)-, (e)-, Monomethanesulphonate

79. 2-thiophenepropanoic Acid, Alpha-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1h-imidazol-5-yl]methylene]-, (alphae)-, Methanesulfonate (1:1)

80. 4-({2-butyl-5-[(1e)-2-carboxy-3-(2-thienyl)prop-1-en-1-yl]-1h-imidazol-1-yl}methyl)benzoic Acid Methanesulfonate

81. 4-[[2-butyl-5-[(e)-2-carboxy-3-(2-thienyl)prop-1-enyl]imidazol-1-yl]methyl]benzoic Acid; Methanesulfonic Acid

82. 4-[[2-butyl-5-[(e)-2-carboxy-3-thiophen-2-ylprop-1-enyl]imidazol-1-yl]methyl]benzoic Acid;methanesulfonic Acid.

83. Eprosartan Mesylate

84. Sk&f 108566

85. (?e)-?-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1h-imidazol-5-yl]methylene]-2-thiophenepropanoic Acid Methanesulfonate

2.4 Create Date
2005-10-11
3 Chemical and Physical Properties
Molecular Weight 520.6 g/mol
Molecular Formula C24H28N2O7S2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count10
Exact Mass520.13379358 g/mol
Monoisotopic Mass520.13379358 g/mol
Topological Polar Surface Area183 Ų
Heavy Atom Count35
Formal Charge0
Complexity711
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameEprosartan mesylate
PubMed HealthEprosartan (By mouth)
Drug ClassesCardiovascular Agent, Renal Protective Agent
Drug LabelTEVETEN (eprosartan mesylate) is a non-biphenyl non-tetrazole angiotensin II receptor (AT1) antagonist. A selective non-peptide molecule, TEVETEN is chemically described as the monomethanesulfonate of (E )-2-butyl-1-(p-carboxybenzyl)--2-thienyl...
Active IngredientEprosartan mesylate
Dosage FormTablet
RouteOral
Strengtheq 600mg base; eq 400mg base
Market StatusPrescription
CompanyMylan Pharms

2 of 4  
Drug NameTeveten
Drug LabelTEVETEN (eprosartan mesylate) is a non-biphenyl non-tetrazole angiotensin II receptor (AT1) antagonist. A selective non-peptide molecule, TEVETEN is chemically described as the monomethanesulfonate of (E )-2-butyl-1-(p-carboxybenzyl)--2-thienyl...
Active IngredientEprosartan mesylate
Dosage FormTablet
RouteOral
Strengtheq 600mg base; eq 400mg base
Market StatusPrescription
CompanyAbbvie

3 of 4  
Drug NameEprosartan mesylate
PubMed HealthEprosartan (By mouth)
Drug ClassesCardiovascular Agent, Renal Protective Agent
Drug LabelTEVETEN (eprosartan mesylate) is a non-biphenyl non-tetrazole angiotensin II receptor (AT1) antagonist. A selective non-peptide molecule, TEVETEN is chemically described as the monomethanesulfonate of (E )-2-butyl-1-(p-carboxybenzyl)--2-thienyl...
Active IngredientEprosartan mesylate
Dosage FormTablet
RouteOral
Strengtheq 600mg base; eq 400mg base
Market StatusPrescription
CompanyMylan Pharms

4 of 4  
Drug NameTeveten
Drug LabelTEVETEN (eprosartan mesylate) is a non-biphenyl non-tetrazole angiotensin II receptor (AT1) antagonist. A selective non-peptide molecule, TEVETEN is chemically described as the monomethanesulfonate of (E )-2-butyl-1-(p-carboxybenzyl)--2-thienyl...
Active IngredientEprosartan mesylate
Dosage FormTablet
RouteOral
Strengtheq 600mg base; eq 400mg base
Market StatusPrescription
CompanyAbbvie

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Antihypertensive Agents

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)


Angiotensin II Type 2 Receptor Blockers

Agents that antagonize the ANGIOTENSIN II TYPE 2 RECEPTOR. (See all compounds classified as Angiotensin II Type 2 Receptor Blockers.)


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HAVRE","customer":"VIATRIS","customerCountry":"FRANCE","quantity":"3680.38","actualQuantity":"3680.38","unit":"KGS","unitRateFc":"227.1","totalValueFC":"956581.1","currency":"CHF","unitRateINR":21839.649210135907,"date":"05-Oct-2024","totalValueINR":"80378208.16","totalValueInUsd":"956581.1","indian_port":"Ahmedabad ICD","hs_no":"29420090","bill_no":"4607745","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad ICD","supplierAddress":"BHADRA-RAJ CHAMBER,,SWASTIK CROSS, AHMEDABAD,GUJARAT","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732300200,"product":"EPROSARTAN MESYLATE","address":"Plot no 564-A-22, Road No 92 ,? Jubilee Hills, Film Nagar, Shaikpet, ,? Hyderabad , ?HYDERABAD ,? TELANGANA,? 500096","city":"N\/A","supplier":"TIANISH LABORATORIES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"FOS SUR MER","customer":"VIATRIS","customerCountry":"FRANCE","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"240","totalValueFC":"237758.4","currency":"USD","unitRateINR":20064,"date":"23-Nov-2024","totalValueINR":"20064000","totalValueInUsd":"237758.4","indian_port":"Hyderabad ICD","hs_no":"29332990","bill_no":"5853902","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad ICD","supplierAddress":"Plot no 564-A-22, Road No 92 ,? Jubilee Hills, Film Nagar, Shaikpet, ,? Hyderabad , ?HYDERABAD ,? TELANGANA,? 500096, N\/A","customerAddress":""}]
09-Jun-2021
23-Nov-2024
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Average Price (USD/KGS)

Number of Transactions

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Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

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ABOUT THIS PAGE

Eprosartan Mesylate Manufacturers

A Eprosartan Mesylate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Eprosartan Mesylate, including repackagers and relabelers. The FDA regulates Eprosartan Mesylate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Eprosartan Mesylate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Eprosartan Mesylate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Eprosartan Mesylate Suppliers

A Eprosartan Mesylate supplier is an individual or a company that provides Eprosartan Mesylate active pharmaceutical ingredient (API) or Eprosartan Mesylate finished formulations upon request. The Eprosartan Mesylate suppliers may include Eprosartan Mesylate API manufacturers, exporters, distributors and traders.

click here to find a list of Eprosartan Mesylate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Eprosartan Mesylate USDMF

A Eprosartan Mesylate DMF (Drug Master File) is a document detailing the whole manufacturing process of Eprosartan Mesylate active pharmaceutical ingredient (API) in detail. Different forms of Eprosartan Mesylate DMFs exist exist since differing nations have different regulations, such as Eprosartan Mesylate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Eprosartan Mesylate DMF submitted to regulatory agencies in the US is known as a USDMF. Eprosartan Mesylate USDMF includes data on Eprosartan Mesylate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Eprosartan Mesylate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Eprosartan Mesylate suppliers with USDMF on PharmaCompass.

Eprosartan Mesylate KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Eprosartan Mesylate Drug Master File in Korea (Eprosartan Mesylate KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Eprosartan Mesylate. The MFDS reviews the Eprosartan Mesylate KDMF as part of the drug registration process and uses the information provided in the Eprosartan Mesylate KDMF to evaluate the safety and efficacy of the drug.

After submitting a Eprosartan Mesylate KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Eprosartan Mesylate API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Eprosartan Mesylate suppliers with KDMF on PharmaCompass.

Eprosartan Mesylate WC

A Eprosartan Mesylate written confirmation (Eprosartan Mesylate WC) is an official document issued by a regulatory agency to a Eprosartan Mesylate manufacturer, verifying that the manufacturing facility of a Eprosartan Mesylate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Eprosartan Mesylate APIs or Eprosartan Mesylate finished pharmaceutical products to another nation, regulatory agencies frequently require a Eprosartan Mesylate WC (written confirmation) as part of the regulatory process.

click here to find a list of Eprosartan Mesylate suppliers with Written Confirmation (WC) on PharmaCompass.

Eprosartan Mesylate NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Eprosartan Mesylate as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Eprosartan Mesylate API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Eprosartan Mesylate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Eprosartan Mesylate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Eprosartan Mesylate NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Eprosartan Mesylate suppliers with NDC on PharmaCompass.

Eprosartan Mesylate GMP

Eprosartan Mesylate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Eprosartan Mesylate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Eprosartan Mesylate GMP manufacturer or Eprosartan Mesylate GMP API supplier for your needs.

Eprosartan Mesylate CoA

A Eprosartan Mesylate CoA (Certificate of Analysis) is a formal document that attests to Eprosartan Mesylate's compliance with Eprosartan Mesylate specifications and serves as a tool for batch-level quality control.

Eprosartan Mesylate CoA mostly includes findings from lab analyses of a specific batch. For each Eprosartan Mesylate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Eprosartan Mesylate may be tested according to a variety of international standards, such as European Pharmacopoeia (Eprosartan Mesylate EP), Eprosartan Mesylate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Eprosartan Mesylate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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