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    Chemistry

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    Also known as: 81409-90-7, Dostinex, Cabaser, Cabergolinum [latin], Cabergolina [spanish], Cabergolinum
    Molecular Formula
    C26H37N5O2
    Molecular Weight
    451.6  g/mol
    InChI Key
    KORNTPPJEAJQIU-KJXAQDMKSA-N
    FDA UNII
    LL60K9J05T
    Cabergoline
    An ergoline derivative and dopamine D2-agonist that inhibits PROLACTIN secretion. It is used in the management of HYPERPROLACTINEMIA, and to suppress lactation following childbirth for medical reasons. Cabergoline is also used in the management of PARKINSON DISEASE.
    Cabergoline is an Ergot Derivative.
    1 2D Structure

    Cabergoline

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (6aR,9R,10aR)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
    2.1.2 InChI
    InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21-,23-/m1/s1
    2.1.3 InChI Key
    KORNTPPJEAJQIU-KJXAQDMKSA-N
    2.1.4 Canonical SMILES
    CCNC(=O)N(CCCN(C)C)C(=O)C1CC2C(CC3=CNC4=CC=CC2=C34)N(C1)CC=C
    2.1.5 Isomeric SMILES
    CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)CC=C
    2.2 Other Identifiers
    2.2.1 UNII
    LL60K9J05T
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 1-((6-allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea

    2. 1-ethyl-2-(3'-dimethylaminopropyl)-3-(6'-allylergoline-8'-beta-carbonyl)urea Diphosphate

    3. Cabaser

    4. Cabaseril

    5. Cabergoline Diphosphate

    6. Dostinex

    7. Fce 21336

    8. Fce-21336

    9. Galastop

    2.3.2 Depositor-Supplied Synonyms

    1. 81409-90-7

    2. Dostinex

    3. Cabaser

    4. Cabergolinum [latin]

    5. Cabergolina [spanish]

    6. Cabergolinum

    7. Cabergolina

    8. Fce-21336

    9. Fce 21336

    10. Velactis

    11. 1-((6-allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea

    12. Cabaseril

    13. Chebi:3286

    14. Ll60k9j05t

    15. Dsstox_cid_2719

    16. 1-[(6-allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

    17. 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea

    18. (8r)-6-allyl-n-[3-(dimethylamino)propyl]-n-(ethylcarbamoyl)ergoline-8-carboxamide

    19. Dsstox_rid_76698

    20. Dsstox_gsid_22719

    21. (6ar,9r,10ar)-7-allyl-n-(3-(dimethylamino)propyl)-n-(ethylcarbamoyl)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide

    22. (8beta)-n-[3-(dimethylamino)propyl]-n-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide

    23. Sogilen

    24. Dostinex (tn)

    25. 1-[3-(dimethylamino)propyl]-3-ethyl-1-{[(2r,4r,7r)-6-(prop-2-en-1-yl)-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraen-4-yl]carbonyl}urea

    26. Cabaser (tn)

    27. Cas-81409-90-7

    28. Sr-05000001493

    29. Brn 6020775

    30. Unii-ll60k9j05t

    31. Caberlin

    32. Ncgc00167821-01

    33. Cabergoline [usan:usp:inn:ban]

    34. Cg-101

    35. Mfcd00867887

    36. Cabergoline [mi]

    37. Cabergoline [inn]

    38. Cabergoline [jan]

    39. Cabergoline [usan]

    40. Gtpl37

    41. Cabergoline [vandf]

    42. Cabergoline [mart.]

    43. Schembl42292

    44. Cabergoline [usp-rs]

    45. Cabergoline [who-dd]

    46. (8beta)-n-[3-(dimethylamino)propyl]-n-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide

    47. Bidd:gt0775

    48. Cabergoline (jan/usp/inn)

    49. Chembl1201087

    50. Dtxsid6022719

    51. Cabergoline, >=98% (hplc)

    52. Cabergoline [orange Book]

    53. Cabergoline [ep Monograph]

    54. Hms2090a09

    55. Hms3886h05

    56. Cabergoline [usp Monograph]

    57. Zinc3800008

    58. Tox21_112589

    59. Bdbm50426497

    60. S5842

    61. Akos015961587

    62. Tox21_112589_1

    63. Db00248

    64. Fce-21336fce-21336

    65. Cabergoline [ema Epar Veterinary]

    66. Ncgc00344544-01

    67. (8beta)-n-[3-(dimethylamino)propyl]-n-[(ethylamino)carbonyl]-6-prop-2-en-1-ylergoline-8-carboxamide

    68. Ac-26126

    69. Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-n-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)-

    70. Ergoline-8beta-carboxamide, N-(3-(dimethylamino)propyl)-n-((ethylamino)carbonyl)-6-(2-propenyl)-

    71. Hy-15296

    72. C08187

    73. D00987

    74. F17353

    75. Ab01275484-01

    76. 409c907

    77. Q423308

    78. Sr-05000001493-1

    79. Sr-05000001493-2

    80. Brd-k86882815-001-01-6

    81. Cabergoline, European Pharmacopoeia (ep) Reference Standard

    82. Cabergoline, United States Pharmacopeia (usp) Reference Standard

    83. Ethyl4-methyl-2-pyridin-3-yl-1,3-thiazole-5-carboxylate

    84. 1-((6-allylergolin-8.beta.-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea

    85. 6-allyl-n-[3-(dimethylamino)propyl]-n-[(ethylamino)carbonyl]-ergoline-8beta-carboxamide

    86. N-[3-(dimethylamino)propyl]-n-(ethylcarbamoyl)-6-allyl-ergoline-8beta-carboxamide

    87. (6ar,9r,10ar)-n-[3-(dimethylamino)propyl]-n-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carboxamide

    88. (9r,10ar)-7-allyl-n-(3-(dimethylamino)propyl)-n-(ethylcarbamoyl)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide

    89. Ergoline-8.beta.-carboxamide, N-(3-(dimethylamino)propyl)-n-((ethylamino)carbonyl)-6-(2-propenyl)-

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 451.6 g/mol
    Molecular Formula C26H37N5O2
    XLogP33.4
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count8
    Exact Mass451.29472544 g/mol
    Monoisotopic Mass451.29472544 g/mol
    Topological Polar Surface Area71.7 Ų
    Heavy Atom Count33
    Formal Charge0
    Complexity713
    Isotope Atom Count0
    Defined Atom Stereocenter Count3
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameCabergoline
    PubMed HealthCabergoline (By mouth)
    Drug ClassesAntiparkinsonian, Prolactin Secretion Inhibitor
    Drug LabelCabergoline tablets contain cabergoline, a dopamine receptor agonist. The chemical name for cabergoline is 1-[(6-Allylergolin-8-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea. Its molecular formula is C26H37N5O2, and its molecular weight is 4...
    Active IngredientCabergoline
    Dosage FormTablet
    RouteOral
    Strength0.5mg
    Market StatusPrescription
    CompanyMylan Pharms; Ivax Sub Teva Pharms; Actavis Labs Fl; Apotex; Par Pharm; Impax Labs

    2 of 2  
    Drug NameCabergoline
    PubMed HealthCabergoline (By mouth)
    Drug ClassesAntiparkinsonian, Prolactin Secretion Inhibitor
    Drug LabelCabergoline tablets contain cabergoline, a dopamine receptor agonist. The chemical name for cabergoline is 1-[(6-Allylergolin-8-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea. Its molecular formula is C26H37N5O2, and its molecular weight is 4...
    Active IngredientCabergoline
    Dosage FormTablet
    RouteOral
    Strength0.5mg
    Market StatusPrescription
    CompanyMylan Pharms; Ivax Sub Teva Pharms; Actavis Labs Fl; Apotex; Par Pharm; Impax Labs

    4.2 Drug Indication

    For the treatment of hyperprolactinemic disorders, either idiopathic or due to prolactinoma (prolactin-secreting adenomas). May also be used to manage symptoms of Parkinsonian Syndrome as monotherapy during initial symptomatic management or as an adjunct to levodopa therapy during advanced stages of disease.

    For use in the herd management programme of dairy cows as an aid in the abrupt drying-off by reducing milk production to:

    - reduce milk leakage at drying off;

    - reduce the risk of new intramammary infections during the dry period;

    - reduce discomfort.

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Cabergoline stimulates centrally-located dopaminergic receptors resulting in a number of pharmacologic effects. Five dopamine receptor types from two dopaminergic subfamilies have been identified. The dopaminergic D1 receptor subfamily consists of D1 and D5 subreceptors, which are associated with dyskinesias. The dopaminergic D2 receptor subfamily consists of D2, D3 and D4 subreceptors, which are associated with improvement of symptoms of movement disorders. Thus, agonist activity specific for D2 subfamily receptors, primarily D2 and D3 receptor subtypes, are the primary targets of dopaminergic antiparkinsonian agents. It is thought that postsynaptic D2 stimulation is primarily responsible for the antiparkinsonian effect of dopamine agonists, while presynaptic D2 stimulation confers neuroprotective effects. This semisynthetic ergot derivative exhibits potent agonist activity on dopamine D2- and D3-receptors. It also exhibits: agonist activity (in order of decreasing binding affinities) on 5-hydroxytryptamine (5-HT)2B, 5-HT2A, 5-HT1D, dopamine D4, 5-HT1A, dopamine D1, 5-HT1B and 5-HT2C receptors and antagonist activity on α2B, α2A, and α2C receptors. Parkinsonian Syndrome manifests when approximately 80% of dopaminergic activity in the nigrostriatal pathway of the brain is lost. As this striatum is involved in modulating the intensity of coordinated muscle activity (e.g. movement, balance, walking), loss of activity may result in dystonia (acute muscle contraction), Parkinsonism (including symptoms of bradykinesia, tremor, rigidity, and flattened affect), akathesia (inner restlessness), tardive dyskinesia (involuntary muscle movements usually associated with long-term loss of dopaminergic activity), and neuroleptic malignant syndrome, which manifests when complete blockage of nigrostriatal dopamine occurs. High dopaminergic activity in the mesolimbic pathway of the brain causes hallucinations and delusions; these side effects of dopamine agonists are manifestations seen in patients with schizophrenia who have overractivity in this area of the brain. The hallucinogenic side effects of dopamine agonists may also be due to 5-HT2A agonism. The tuberoinfundibular pathway of the brain originates in the hypothalamus and terminates in the pituitary gland. In this pathway, dopamine inhibits lactotrophs in anterior pituitary from secreting prolactin. Increased dopaminergic activity in the tuberoinfundibular pathway inhibits prolactin secretion.

    5.2 MeSH Pharmacological Classification

    Antiparkinson Agents

    Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists. (See all compounds classified as Antiparkinson Agents.)

    Dopamine Agonists

    Drugs that bind to and activate dopamine receptors. (See all compounds classified as Dopamine Agonists.)

    5.3 FDA Pharmacological Classification
    5.3.1 Active Moiety
    CABERGOLINE
    5.3.2 FDA UNII
    LL60K9J05T
    5.3.3 Pharmacological Classes
    Ergot Derivative [EPC]; Ergolines [CS]
    5.4 ATC Code

    QG02CB03

    G02CB03

    S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

    G - Genito urinary system and sex hormones

    G02 - Other gynecologicals

    G02C - Other gynecologicals

    G02CB - Prolactine inhibitors

    G02CB03 - Cabergoline

    N - Nervous system

    N04 - Anti-parkinson drugs

    N04B - Dopaminergic agents

    N04BC - Dopamine agonists

    N04BC06 - Cabergoline

    5.5 Absorption, Distribution and Excretion

    Absorption

    First-pass effect is seen, however the absolute bioavailability is unknown.

    Route of Elimination

    After oral dosing of radioactive cabergoline to five healthy volunteers, approximately 22% and 60% of the dose was excreted within 20 days in the urine and feces, respectively. Less than 4% of the dose was excreted unchanged in the urine.

    Clearance

    renal cl=0,008 L/min

    nonrenal cl=3.2 L/min

    5.6 Metabolism/Metabolites

    Hepatic. Cabergoline is extensively metabolized, predominately via hydrolysis of the acylurea bond of the urea moiety. Cytochrome P-450 mediated metabolism appears to be minimal. The main metabolite identified in urine is 6-allyl-8b-carboxy-ergoline (4-6% of dose). Three other metabolites were identified urine (less than 3% of dose).

    5.7 Biological Half-Life

    The elimination half-life is estimated from urinary data of 12 healthy subjects to range between 63 to 69 hours.

    5.8 Mechanism of Action

    The dopamine D2 receptor is a 7-transmembrane G-protein coupled receptor associated with Gi proteins. In lactotrophs, stimulation of dopamine D2 causes inhibition of adenylyl cyclase, which decreases intracellular cAMP concentrations and blocks IP3-dependent release of Ca2+ from intracellular stores. Decreases in intracellular calcium levels may also be brought about via inhibition of calcium influx through voltage-gated calcium channels, rather than via inhibition of adenylyl cyclase. Additionally, receptor activation blocks phosphorylation of p42/p44 MAPK and decreases MAPK/ERK kinase phosphorylation. Inhibition of MAPK appears to be mediated by c-Raf and B-Raf-dependent inhibition of MAPK/ERK kinase. Dopamine-stimulated growth hormone release from the pituitary gland is mediated by a decrease in intracellular calcium influx through voltage-gated calcium channels rather than via adenylyl cyclase inhibition. Stimulation of dopamine D2 receptors in the nigrostriatal pathway leads to improvements in coordinated muscle activity in those with movement disorders. Cabergoline is a long-acting dopamine receptor agonist with a high affinity for D2 receptors. Receptor-binding studies indicate that cabergoline has low affinity for dopamine D1, α1,- and α2- adrenergic, and 5-HT1- and 5-HT2-serotonin receptors.

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EAST","city":"MUMBAI,MAHARASHTRA","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"NA","customer":"CENTAUR PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.55","actualQuantity":"0.55","unit":"KGS","unitRateFc":"350000","totalValueFC":"194125.2","currency":"USD","unitRateINR":"26285000","date":"22-Nov-2021","totalValueINR":"14456750","totalValueInUsd":"194125.2","indian_port":"BOMBAY AIR","hs_no":"29396900","bill_no":"6358814","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"CENTAUR HOUSE, SHANTI NAGAR,,VAKOL A, SANTACRUZ - EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1640197800,"product":"CABERGOLINE","address":"SUN HOUSE,PLOT NO.201 B\/1,WESTERN EXPRESS HIGHWAY,GOREGAON EAST Conta","city":"MUMBAI","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"N\/A","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"190000","totalValueFC":"194342.4","currency":"USD","unitRateINR":"14658500","date":"23-Dec-2021","totalValueINR":"14658500","totalValueInUsd":"194342.4","indian_port":"BOMBAY AIR","hs_no":"29396900","bill_no":"6805038","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"","customerAddress":"SUN HOUSE,PLOT NO.201 B\/1,WESTERN EXPRESS HIGHWAY,GOREGAON EAST Conta"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1645813800,"product":"CABERGOLINE","address":"SUN HOUSE,PLOT NO.201 B\/1,WESTERN EXPRESS HIGHWAY,GOREGAON EAST Conta","city":"MUMBAI","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"NA","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"190000","totalValueFC":"38554.2","currency":"USD","unitRateINR":"14449500","date":"26-Feb-2022","totalValueINR":"2889900","totalValueInUsd":"38554.2","indian_port":"BOMBAY AIR","hs_no":"29396900","bill_no":"7656838","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SUN HOUSE,PLOT NO.201 B\/1,WESTERN EXPRESS HIGHWAY,GOREGAON EAST Conta"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1647887400,"product":"CABERGOLINE","address":"SPARC TANDALJA","city":"VADODARA","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"NA","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"0.42","actualQuantity":"0.42","unit":"KGS","unitRateFc":"375000","totalValueFC":"158906.2","currency":"USD","unitRateINR":"28837500","date":"22-Mar-2022","totalValueINR":"12111750","totalValueInUsd":"158906.2","indian_port":"DELHI AIR","hs_no":"29419090","bill_no":"7965212","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SPARC TANDALJA"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1655922600,"product":"CABERGOLINE -0.550KGS- FOC (FREE SUPPLY OF RAW MATERIAL AGAINST EXPORT ORDER)","address":"CENTAUR HOUSE, SHANTI NAGAR,,VAKOL A, SANTACRUZ - EAST","city":"MUMBAI,MAHARASHTRA","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"NA","customer":"CENTAUR PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.55","actualQuantity":"0.55","unit":"KGS","unitRateFc":"350000","totalValueFC":"194806.4","currency":"USD","unitRateINR":"27632500","date":"23-Jun-2022","totalValueINR":"15197875","totalValueInUsd":"194806.4","indian_port":"BOMBAY AIR","hs_no":"29396900","bill_no":"9245666","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"CENTAUR HOUSE, SHANTI NAGAR,,VAKOL A, SANTACRUZ - EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670956200,"product":"CABERGOLINE, (BATCH NO: 70235001122)","address":"SPARC TANDALJA","city":"VADODARA","supplier":"TEVA PHARMACEUTICAL INDUSTRIES","supplierCountry":"CZECH REPUBLIC","foreign_port":"NA","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"394500","totalValueFC":"78511","currency":"USD","unitRateINR":"32349000","date":"14-Dec-2022","totalValueINR":"6469800","totalValueInUsd":"78511","indian_port":"DELHI AIR","hs_no":"29396900","bill_no":"3740509","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SPARC TANDALJA"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1683225000,"product":"CABERGOLINE BATCH NO 70235000323","address":"SUN HOUSE,PLOT NO.201 B,1,WESTERN ,EXPRESS HIGHWAY,GOREGAON ,EAST","city":"MUMBAI","supplier":"M S TEVI API B V","supplierCountry":"CZECH REPUBLIC","foreign_port":"PRAGUE RUZYNE","customer":"SUN PHARMACEUTICAL INDUSTRIES LIMITED","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"152000","totalValueFC":"152583.3","currency":"USD","unitRateINR":"12555200","date":"05-May-2023","totalValueINR":"12555200","totalValueInUsd":"152583.3","indian_port":"BOMBAY AIR","hs_no":"29396900","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"Czech Republic","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE RUZYNE","supplierAddress":"","customerAddress":"SUN HOUSE,PLOT NO.201 B,1,WESTERN ,EXPRESS HIGHWAY,GOREGAON ,EAST"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1693420200,"product":"CABERGOLINE 600 GMS","address":"H.NO. 1-2-11\/1, B-15-2, 1ST FLOOR, ,,STREET NO. 2, HABSIGUDA, ,KAKATIYANAGAR ABOVE SBI BANKHYDERAB","city":"HYDERABAD","supplier":"WELDING GMBH & CO.KG","supplierCountry":"CZECH REPUBLIC","foreign_port":"NA","customer":"OPTIMUS PHARMA","customerCountry":"INDIA","quantity":"0.60","actualQuantity":"0.6","unit":"KGS","unitRateFc":"350000","totalValueFC":"212654","currency":"USD","unitRateINR":"29065535.7","date":"31-Aug-2023","totalValueINR":"17615476.2","totalValueInUsd":"212654","indian_port":"HYDERABAD AIR","hs_no":"29396900","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"H.NO. 1-2-11\/1, B-15-2, 1ST FLOOR, ,,STREET NO. 2, HABSIGUDA, ,KAKATIYANAGAR ABOVE SBI BANKHYDERAB"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1701714600,"product":"CABERGOLINE -0.500KGS- FOC (FREE SUPPLY OF RAW MATERIAL AGAINST EXPORT ORDER)","address":"CENTAUR HOUSE, SHANTI NAGAR,","city":"MUMBAI ,MAHARASHTRA","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"PRAGUE - RUZYNE","customer":"CENTAUR PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"350000","totalValueFC":"185995","currency":"USD","unitRateINR":"30965620","date":"05-Dec-2023","totalValueINR":"15482810","totalValueInUsd":"185995","indian_port":"Bombay Air","hs_no":"29396900","bill_no":"9080647","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE - RUZYNE","supplierAddress":"400 INTERPACE PARKWAY, MORRIS CORPORATE PARK III PARSIPPANY, NJ 07054USA BILLED TO: INGENUS PHARMACEUTIC United States","customerAddress":"CENTAUR HOUSE, SHANTI NAGAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1706121000,"product":"CABERGOLINE- (BATCH.NO 230100607) (GOODS RETURNED BACK TO THE SUPPLIER FOR RE-PROCESSING)","address":"NO.1,2ND FLOOR,OPP CANARA BANK,","city":"BANGALORE","supplier":"JAZEERA PHARMACEUTICALS INDUSTRIESAL","supplierCountry":"INDIA","foreign_port":"RIYADH","customer":"GLOBAL CALCIUM","customerCountry":"INDIA","quantity":"0.24","actualQuantity":"0.24358","unit":"KGS","unitRateFc":"210000","totalValueFC":"51953.1","currency":"USD","unitRateINR":"17726871.6","date":"25-Jan-2024","totalValueINR":"4317911.39","totalValueInUsd":"51953.1","indian_port":"Bangalore Air","hs_no":"29396900","bill_no":"9837255","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"RIYADH","supplierAddress":"PO . BOX 10622911666 RIYADH-SAUDIARABIA SAUDI ARABIA","customerAddress":"NO.1,2ND FLOOR,OPP CANARA BANK,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713897000,"product":"CABERGOLINE - 0.500KGS- FOC (FREE SUPPLY OF RAW MATERIAL AGAINST EXPORT ORDER)","address":"CENTAUR HOUSE, SHANTI NAGAR,","city":"MUMBAI ,MAHARASHTRA","supplier":"TEVA API","supplierCountry":"CZECH REPUBLIC","foreign_port":"PRAGUE - RUZYNE","customer":"CENTAUR PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"350000","totalValueFC":"186068","currency":"USD","unitRateINR":"31076080","date":"24-Apr-2024","totalValueINR":"15538040","totalValueInUsd":"186068","indian_port":"Bombay Air","hs_no":"29396900","bill_no":"3177451","productDescription":"API","marketType":"REGULATED MARKET","country":"CZECH REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE - RUZYNE","supplierAddress":"400 INTERPACE PARKWAY, MORRIS CORPORATE PARK III PARSIPPANY, NJ 07054USA BILLED TO: INGENUS PHARMACEUTIC United States","customerAddress":"CENTAUR HOUSE, SHANTI NAGAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1716316200,"product":"CABERGOLINE (QTY:14 X 125 MG, VALUE: USD 2543\/EACH) (FOC)","address":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,","city":"TURKAPALLY(V),SHAMEERPET, HYDERABAD","supplier":"USP","supplierCountry":"ITALY","foreign_port":"WASHINGTON, DULLES I","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.00175","unit":"KGS","unitRateFc":"20344000","totalValueFC":"36625.7","currency":"USD","unitRateINR":"1744518120","date":"22-May-2024","totalValueINR":"3052906.71","totalValueInUsd":"36625.7","indian_port":"Hyderabad Air","hs_no":"29396900","bill_no":"3604587","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"7135 ENGLISH MUFFIN WAY FREDERICK,MD 21704 USA Frederick, , United States United States","customerAddress":"P.NO. D6 D8, SY.NO. 234\/2,234\/3,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1719858600,"product":"CABERGOLINE(702350)","address":"FLAT NO 305, TARA TOWERS, SALEEM NAGAR, MALAKPET, HEYDERABAD","city":"HYDERABAD","supplier":"TEVA API","supplierCountry":"NETHERLANDS","foreign_port":"PRAGUE - RUZYNE","customer":"RITSA PHARMA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.21","actualQuantity":"0.21","unit":"KGS","unitRateFc":"350000","totalValueFC":"74123.3","currency":"USD","unitRateINR":"29505000","date":"02-Jul-2024","totalValueINR":"6196050","totalValueInUsd":"74123.3","indian_port":"Hyderabad Air","hs_no":"29182990","bill_no":"4290760","productDescription":"API","marketType":"REGULATED MARKET","country":"NETHERLANDS","selfForZScoreResived":"Pharma Grade","supplierPort":"PRAGUE - RUZYNE","supplierAddress":"Piet Hein Building, Piet Heinkade107,1019 GM AmsterdamThe Netherlands NL","customerAddress":"FLAT NO 305, TARA TOWERS, SALEEM NAGAR, MALAKPET, HEYDERABAD"}]
    04-Mar-2021
    27-Nov-2024
    KGS
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    ABOUT THIS PAGE

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- Manufacturers

    A Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)-, including repackagers and relabelers. The FDA regulates Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- Suppliers

    A Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- supplier is an individual or a company that provides Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- active pharmaceutical ingredient (API) or Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- finished formulations upon request. The Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- suppliers may include Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- API manufacturers, exporters, distributors and traders.

    click here to find a list of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- USDMF

    A Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- DMF (Drug Master File) is a document detailing the whole manufacturing process of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- active pharmaceutical ingredient (API) in detail. Different forms of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- DMFs exist exist since differing nations have different regulations, such as Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- DMF submitted to regulatory agencies in the US is known as a USDMF. Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- USDMF includes data on Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)-'s chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- suppliers with USDMF on PharmaCompass.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- Drug Master File in Japan (Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- JDMF) empowers Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- JDMF during the approval evaluation for pharmaceutical products. At the time of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- suppliers with JDMF on PharmaCompass.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- Drug Master File in Korea (Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)-. The MFDS reviews the Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- KDMF as part of the drug registration process and uses the information provided in the Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- suppliers with KDMF on PharmaCompass.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CEP

    A Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CEP of the European Pharmacopoeia monograph is often referred to as a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- Certificate of Suitability (COS). The purpose of a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- to their clients by showing that a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CEP has been issued for it. The manufacturer submits a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CEP (COS) as part of the market authorization procedure, and it takes on the role of a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CEP holder for the record. Additionally, the data presented in the Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- DMF.

    A Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- suppliers with CEP (COS) on PharmaCompass.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- WC

    A Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- written confirmation (Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- WC) is an official document issued by a regulatory agency to a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- manufacturer, verifying that the manufacturing facility of a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- APIs or Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- finished pharmaceutical products to another nation, regulatory agencies frequently require a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- WC (written confirmation) as part of the regulatory process.

    click here to find a list of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- suppliers with Written Confirmation (WC) on PharmaCompass.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- suppliers with NDC on PharmaCompass.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- GMP

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- GMP manufacturer or Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- GMP API supplier for your needs.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CoA

    A Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CoA (Certificate of Analysis) is a formal document that attests to Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)-'s compliance with Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- specifications and serves as a tool for batch-level quality control.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CoA mostly includes findings from lab analyses of a specific batch. For each Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- may be tested according to a variety of international standards, such as European Pharmacopoeia (Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- EP), Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-, (8-beta)- USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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