DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Contact Supplier

Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 USDMF, 1 NDC API

1 API Suppliers
1 USDMF
1 NDC API

MARKET PLACE

1 APIs

marketPlace
1 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 51543-39-6, (s)-flurbiprofen, (s)-(+)-2-fluoro-alpha-methyl-4-biphenylacetic acid, (s)-2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoic acid, S-flurbiprofen, (2s)-2-(2-fluorobiphenyl-4-yl)propanoic acid

Molecular Formula

C₁₅H₁₃FO₂

Molecular Weight

244.26 g/mol

InChI Key

SYTBZMRGLBWNTM-JTQLQIEISA-N

FDA UNII

J5ZZK9P7MX

Esflurbiprofen is under investigation in clinical trial NCT03434197 (Safety and Efficacy of SFPP in Knee Osteoarthritis).

1 2D Structure

Esflurbiprofen

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2S)-2-(3-fluoro-4-phenylphenyl)propanoic acid

2.1.2 InChI

InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m0/s1

2.1.3 InChI Key

SYTBZMRGLBWNTM-JTQLQIEISA-N

2.1.4 Canonical SMILES

CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O

2.1.5 Isomeric SMILES

C[C@@H](C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O

2.2 Other Identifiers

2.2.1 UNII

J5ZZK9P7MX

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 51543-39-6

2. (s)-flurbiprofen

3. (s)-(+)-2-fluoro-alpha-methyl-4-biphenylacetic Acid

4. (s)-2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoic Acid

5. S-flurbiprofen

6. (2s)-2-(2-fluorobiphenyl-4-yl)propanoic Acid

7. Flurbiprofen, (s)-

8. (s)-2-(2-fluorobiphenyl-4-yl)propanoic Acid

9. Bts 24332

10. Bts-24332

11. Tt-063

12. J5zzk9p7mx

13. (2s)-2-(3-fluoro-4-phenylphenyl)propanoic Acid

14. (s)-2-fluoro-alpha-methyl-4-biphenylacetic Acid

15. Chembl435298

16. Chebi:42446

17. Esflurbiprofen (jan)

18. Esflurbiprofen [jan]

19. (s)-2-fluoro-alpha-methyl(1,1'-biphenyl)-4-acetic Acid

20. Esflurbiprofene

21. Esflurbiprofeno

22. Esflurbiprofenum

23. Sfpp

24. Smr000471846

25. Esflurbiprofene [french]

26. Esflurbiprofenum [latin]

27. (s)-(+)-flurbiprofen

28. Esflurbiprofeno [spanish]

29. Unii-j5zzk9p7mx

30. Esflurbiprofen [inn:ban]

31. Flurwood

32. Urbifen

33. (+)-flurbiprofen

34. Flp

35. Einecs 257-263-1

36. Flurbiprofen-(s)-(+)

37. Esflurbiprofen [inn]

38. Zinc323

39. Mls001066337

40. Mls001333207

41. Mls001333208

42. Schembl505817

43. Gtpl9420

44. Esflurbiprofen [who-dd]

45. (s)-2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoicacid

46. Dtxsid201316678

47. Hms2232e18

48. Hms3649p05

49. Hms3884i06

50. Bcp24046

51. Bdbm50172479

52. Mfcd00866152

53. Nsc685700

54. S1679

55. Akos016844131

56. Ccg-266907

57. Nsc-685700

58. As-78108

59. Hy-15123

60. Nci60_030810

61. Nci60_030811

62. Db-008733

63. Cs-0003779

64. Sw202926-2

65. A21120

66. D10254

67. Sr-01000946685

68. (s)-(+)-2-fluoro-?-methyl-4-biphenylacetic Acid

69. Sr-01000946685-1

70. Q27104495

71. (s)-(+)-2-fluoro-.alpha.-methyl-4-biphenylacetic Acid

72. (2s)-2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic Acid

73. (s)-2-fluoro-.alpha.-methyl-4-biphenylacetic Acid

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₅H₁₃FO₂
Molecular Weight	244.26 g/mol
XLogP3	4.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	244.08995782 g/mol
Monoisotopic Mass	244.08995782 g/mol
Topological Polar Surface Area	37.3 Å²
Heavy Atom Count	18
Formal Charge	0
Complexity	286
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1