Find Ethacizine manufacturers, exporters & distributors on PharmaCompass

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Synopsis

ACTIVE PHARMA INGREDIENTS

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API REF. PRICE (USD/KG)

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Chemistry

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Also known as: Etacizin, Ethacizin, Ethacyzin, 33414-33-4, Etmozine daa, Nik-244
Molecular Formula
C22H27N3O3S
Molecular Weight
413.5  g/mol
InChI Key
PQXGNJKJMFUPPM-UHFFFAOYSA-N
FDA UNII
FE5SPV1Z6G

Ethacizine
1 2D Structure

Ethacizine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
ethyl N-[10-[3-(diethylamino)propanoyl]phenothiazin-2-yl]carbamate
2.1.2 InChI
InChI=1S/C22H27N3O3S/c1-4-24(5-2)14-13-21(26)25-17-9-7-8-10-19(17)29-20-12-11-16(15-18(20)25)23-22(27)28-6-3/h7-12,15H,4-6,13-14H2,1-3H3,(H,23,27)
2.1.3 InChI Key
PQXGNJKJMFUPPM-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCN(CC)CCC(=O)N1C2=CC=CC=C2SC3=C1C=C(C=C3)NC(=O)OCC
2.2 Other Identifiers
2.2.1 UNII
FE5SPV1Z6G
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 10-(3-(diethylamino)-1-oxopropyl)-10h-(phenothiazin-2-yl)carbamic Acid Ethyl Ester

2. 2-(ethoxycarbonylamino)-10-(3-(diethylamino)propionyl)phenothiazine

3. Etacizin

4. Etacyzine

5. Etatsizin

6. Etatsizine

7. Nik 244

8. Nik0244

2.3.2 Depositor-Supplied Synonyms

1. Etacizin

2. Ethacizin

3. Ethacyzin

4. 33414-33-4

5. Etmozine Daa

6. Nik-244

7. Fe5spv1z6g

8. Nsc-621878

9. Ethyl N-[10-[3-(diethylamino)propanoyl]phenothiazin-2-yl]carbamate

10. Ez-55

11. Ethmozine Daa

12. Ez 55

13. Unii-fe5spv1z6g

14. Brn 4827533

15. Ethyl (10-(3-(diethylamino)-1-oxopropyl)-10h-phenothiazin-2-yl)carbamate

16. Phenothiazine-2-carbamic Acid, 10-(n,n-diethyl-beta-alanyl)-, Ethyl Ester

17. Ethacizine [mart.]

18. Ethacizine [who-dd]

19. Oprea1_817639

20. Chembl1997663

21. Schembl22882766

22. Dtxsid50187057

23. Chebi:134732

24. Zinc4182572

25. Nsc621878

26. Stk995917

27. Akos001680764

28. Db13645

29. Nsc 621878

30. Carbamic Acid, (10-(3-(diethylamino)-1-oxopropyl)-10h-phenothiazin-2-yl)-, Ethyl Ester

31. Nci60_006381

32. D10503

33. Q15408408

34. Ethyl [10-(n,n-diethyl-beta-alanyl)-10h-phenothiazin-2-yl]carbamate

35. Ethyl 10-(3-(diethylamino)propionyl)phenothiazine-2-carbamate

36. Ethyl N-{10-[3-(diethylamino)propanoyl]-10h-phenothiazin-2-yl}carbamate

37. 4596-66-1

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 413.5 g/mol
Molecular Formula C22H27N3O3S
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Exact Mass413.17731291 g/mol
Monoisotopic Mass413.17731291 g/mol
Topological Polar Surface Area87.2 Ų
Heavy Atom Count29
Formal Charge0
Complexity557
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Arrhythmia Agents

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)


Psychotropic Drugs

A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents). (See all compounds classified as Psychotropic Drugs.)


4.2 ATC Code

C - Cardiovascular system

C01 - Cardiac therapy

C01B - Antiarrhythmics, class i and iii

C01BC - Antiarrhythmics, class ic

C01BC09 - Ethacizine


API SUPPLIERS

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01

Optimus Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM
Not Confirmed
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ABOUT THIS PAGE

Ethacizine Manufacturers

A Ethacizine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ethacizine, including repackagers and relabelers. The FDA regulates Ethacizine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ethacizine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ethacizine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ethacizine Suppliers

A Ethacizine supplier is an individual or a company that provides Ethacizine active pharmaceutical ingredient (API) or Ethacizine finished formulations upon request. The Ethacizine suppliers may include Ethacizine API manufacturers, exporters, distributors and traders.

click here to find a list of Ethacizine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ethacizine GMP

Ethacizine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ethacizine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ethacizine GMP manufacturer or Ethacizine GMP API supplier for your needs.

Ethacizine CoA

A Ethacizine CoA (Certificate of Analysis) is a formal document that attests to Ethacizine's compliance with Ethacizine specifications and serves as a tool for batch-level quality control.

Ethacizine CoA mostly includes findings from lab analyses of a specific batch. For each Ethacizine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ethacizine may be tested according to a variety of international standards, such as European Pharmacopoeia (Ethacizine EP), Ethacizine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ethacizine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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