Find Ethyl Loflazepate manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Victan, Meilax, 29177-84-2, Ethyl fluclozepate, Cm 6912, Loflazepic acid, ethyl ester
Molecular Formula
C18H14ClFN2O3
Molecular Weight
360.8  g/mol
InChI Key
CUCHJCMWNFEYOM-UHFFFAOYSA-N
FDA UNII
VJB5FW9W9J

Ethyl Loflazepate
1 2D Structure

Ethyl Loflazepate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylate
2.1.2 InChI
InChI=1S/C18H14ClFN2O3/c1-2-25-18(24)16-17(23)21-14-8-7-10(19)9-12(14)15(22-16)11-5-3-4-6-13(11)20/h3-9,16H,2H2,1H3,(H,21,23)
2.1.3 InChI Key
CUCHJCMWNFEYOM-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCOC(=O)C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F
2.2 Other Identifiers
2.2.1 UNII
VJB5FW9W9J
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cm 6912

2. Ethyl Flucozepate

3. Victan

2.3.2 Depositor-Supplied Synonyms

1. Victan

2. Meilax

3. 29177-84-2

4. Ethyl Fluclozepate

5. Cm 6912

6. Loflazepic Acid, Ethyl Ester

7. Vjb5fw9w9j

8. Ethyl 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-2-oxo-1h-1,4-benzodiazepine-3-carboxylate

9. 1h-1,4-benzodiazepine-3-carboxylic Acid, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-oxo-, Ethyl Ester

10. Ethylis Loflazepas

11. Ethyl Loflazepate [inn:jan]

12. Loflazepate D'ethyle

13. Loflazepato De Etilo

14. Ethylis Loflazepas [inn-latin]

15. Loflazepate D'ethyle [inn-french]

16. Loflazepato De Etilo [inn-spanish]

17. Einecs 249-489-4

18. Unii-vjb5fw9w9j

19. Brn 0765264

20. Dea No. 2758

21. Meilax (tn)

22. Cm-6912

23. Ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylate

24. 5-25-08-00124 (beilstein Handbook Reference)

25. Ethyl Loflazepate (jan/inn)

26. Schembl156702

27. Ethyl Loflazepate [mi]

28. Ethyl Loflazepate [inn]

29. Ethyl Loflazepate [jan]

30. Chembl1213460

31. Chebi:31573

32. Dtxsid60865475

33. Ethyl Loflazepate [mart.]

34. Ethyl Loflazepate [who-dd]

35. Db01545

36. Ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1h-1,4-benzodiazepine-3-carboxylate

37. D01293

38. Q5404460

39. Ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1h-1,4-benzodiazepine-3-carboxylate #

40. (e)-ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1h-benzo[e][1,4]diazepine-3-carboxylate

41. Ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1h-benzo[e][1,4]diazepine-3-carboxylate

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 360.8 g/mol
Molecular Formula C18H14ClFN2O3
XLogP32.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass360.0676982 g/mol
Monoisotopic Mass360.0676982 g/mol
Topological Polar Surface Area67.8 Ų
Heavy Atom Count25
Formal Charge0
Complexity556
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Anxiety Agents

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)


4.2 ATC Code

N - Nervous system

N05 - Psycholeptics

N05B - Anxiolytics

N05BA - Benzodiazepine derivatives

N05BA18 - Ethyl loflazepate


ABOUT THIS PAGE

Ethyl Loflazepate Manufacturers

A Ethyl Loflazepate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ethyl Loflazepate, including repackagers and relabelers. The FDA regulates Ethyl Loflazepate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ethyl Loflazepate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ethyl Loflazepate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ethyl Loflazepate Suppliers

A Ethyl Loflazepate supplier is an individual or a company that provides Ethyl Loflazepate active pharmaceutical ingredient (API) or Ethyl Loflazepate finished formulations upon request. The Ethyl Loflazepate suppliers may include Ethyl Loflazepate API manufacturers, exporters, distributors and traders.

click here to find a list of Ethyl Loflazepate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ethyl Loflazepate JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Ethyl Loflazepate Drug Master File in Japan (Ethyl Loflazepate JDMF) empowers Ethyl Loflazepate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Ethyl Loflazepate JDMF during the approval evaluation for pharmaceutical products. At the time of Ethyl Loflazepate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Ethyl Loflazepate suppliers with JDMF on PharmaCompass.

Ethyl Loflazepate GMP

Ethyl Loflazepate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ethyl Loflazepate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ethyl Loflazepate GMP manufacturer or Ethyl Loflazepate GMP API supplier for your needs.

Ethyl Loflazepate CoA

A Ethyl Loflazepate CoA (Certificate of Analysis) is a formal document that attests to Ethyl Loflazepate's compliance with Ethyl Loflazepate specifications and serves as a tool for batch-level quality control.

Ethyl Loflazepate CoA mostly includes findings from lab analyses of a specific batch. For each Ethyl Loflazepate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ethyl Loflazepate may be tested according to a variety of international standards, such as European Pharmacopoeia (Ethyl Loflazepate EP), Ethyl Loflazepate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ethyl Loflazepate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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