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Ethyl Noradrianol

Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

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API REF. PRICE (USD/KG)

$ 0

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FDF

0INTERMEDIATES

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Chemistry

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Also known as: Etilefrin, Effortil, 709-55-7, Ethylphenylephrine, 3-[2-(ethylamino)-1-hydroxyethyl]phenol, N-ethylnorphenylephrine

Molecular Formula

C₁₀H₁₅NO₂

Molecular Weight

181.23 g/mol

InChI Key

SQVIAVUSQAWMKL-UHFFFAOYSA-N

FDA UNII

ZB6F8MY53V

A phenylephrine-related beta-1 adrenergic and alpha adrenergic agonist used as a cardiotonic and antihypotensive agent.

1 2D Structure

Ethyl Noradrianol

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

3-[2-(ethylamino)-1-hydroxyethyl]phenol

2.1.2 InChI

InChI=1S/C10H15NO2/c1-2-11-7-10(13)8-4-3-5-9(12)6-8/h3-6,10-13H,2,7H2,1H3

2.1.3 InChI Key

SQVIAVUSQAWMKL-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCNCC(C1=CC(=CC=C1)O)O

2.2 Other Identifiers

2.2.1 UNII

ZB6F8MY53V

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Adrenam

2. Adrianol, Ethyl

3. Bioflutin

4. Cardanat

5. Circupon

6. Effortil

7. Efortil

8. Ethyl Adrianol

9. Ethyladrianol

10. Ethylnorphenylephrine

11. Ethylphenylephrine

12. Eti Puren

13. Eti-puren

14. Etil Von Ct

15. Etilefrin

16. Etilefrin Al

17. Etilefrin Ratiopharm

18. Etilefrin-ratiopharm

19. Etilefrine Hydrochloride

20. Etilefrine Pivalate Hydrochloride

21. Fetanol

22. Hydrochloride, Etilefrine

23. Hydrochloride, Etilefrine Pivalate

24. Phetanol

25. Pivalate Hydrochloride, Etilefrine

26. Thomasin

2.3.2 Depositor-Supplied Synonyms

1. Etilefrin

2. Effortil

3. 709-55-7

4. Ethylphenylephrine

5. 3-[2-(ethylamino)-1-hydroxyethyl]phenol

6. N-ethylnorphenylephrine

7. Ethyladrianol

8. Ethyl Noradrianol

9. Racemic Etilefrine

10. Phetanol

11. Thomasin

12. Ethyl Adrianol

13. Dl-etilefrin

14. Etilefrine [inn]

15. Ethylefrine

16. M-hydroxyphenylethanolethylamine

17. Corcanfol

18. Etilefrin Dl-form

19. 1-(3-hydroxyphenyl)-2-(ethylamino)ethanol

20. Cardanat

21. Efortil

22. Updormin

23. Alpha-((ethylamino)methyl)-m-hydroxybenzyl Alcohol

24. 1-(3'-hydroxyphenyl)-2-ethylaminoethanol

25. Etilefrine-d5

26. 10128-36-6

27. S 40032

28. Zb6f8my53v

29. S 40032-7

30. 3-[2-(ethylamino)-1-hydroxy-ethyl]phenol

31. Mls000881153

32. 709-55-7 (free Base)

33. Etilefrine (inn)

34. Einecs 233-359-9

35. Funasol

36. Benzenemethanol, .alpha.-[(ethylamino)methyl]-3-hydroxy-

37. Etiladrianol

38. Etilephrine

39. Smr000685797

40. S-40032

41. (+-)-etilefrine

42. .alpha.-((ethylamino)methyl)-m-hydroxybenzyl Alcohol

43. Etilefrina [dcit]

44. (+-)-etilefrin

45. Etilefrinum [latin]

46. S-40032-7

47. Ethylephrine Hydrochloride

48. Etilefrina [spanish]

49. Benzyl Alcohol, .alpha.-((ethylamino)methyl)-m-hydroxy-

50. Etilefrina

51. Etilefrinum

52. Etilefrinum [inn-latin]

53. Etilefrine [inn:ban]

54. Einecs 211-910-4

55. Unii-zb6f8my53v

56. (1)-alpha-((ethylamino)methyl)-m-hydroxybenzyl Alcohol

57. Benzenemethanol, Alpha-((ethylamino)methyl)-3-hydroxy-

58. Benzenemethanol, .alpha.-((ethylamino)methyl)-3-hydroxy-

59. R,s-ethylephrine

60. M-hydroxy-alpha-(ethylaminomethyl)benzyl Alcohol

61. Corcanfol (tn)

62. Alpha-(m-hydroxyphenyl)-beta-(ethylamino)ethanol

63. (+-)-ethylephrine

64. Benzyl Alcohol, Alpha-((ethylamino)methyl)-m-hydroxy-

65. Enamine_002760

66. Etilefrin [mi]

67. (.+/-.)-etilefrin

68. Prestwick0_001017

69. Prestwick1_001017

70. Prestwick2_001017

71. Prestwick3_001017

72. (.+/-.)-etilefrine

73. Ec 211-910-4

74. Cid_3306

75. Etilefrine [who-dd]

76. (+/-)-etilefrine

77. Oprea1_593945

78. Bspbio_001173

79. Chembl86882

80. Schembl150802

81. Spbio_003044

82. Bpbio1_001291

83. Dtxsid1023029

84. Niosh/do5600010

85. Bdbm97154

86. Chebi:91518

87. Hms1401n10

88. Hms2233j17

89. Hms3370k09

90. Hy-a0144

91. Bbl027207

92. Stl377784

93. Akos000116366

94. Akos022060703

95. Db08985

96. Idi1_007107

97. Ncgc00179276-01

98. Ncgc00179276-04

99. 3-[2-(ethylamino)-1-hydroxyethyl]phenol #

100. 3-[2-(ethylamino)-1-oxidanyl-ethyl]phenol

101. Ab00514701

102. Cs-0017466

103. Do56000100

104. D07931

105. Ab00514701-08

106. Q417873

107. Brd-a09925278-001-07-6

108. Brd-a09925278-003-03-1

109. Z56836691

110. (+-)-alpha-((ethylamino)methyl)-m-hydroxybenzyl Alcohol

111. .alpha.-(m-hydroxyphenyl)-.beta.-(ethylamino)ethanol

112. Benzyl Alcohol, Alpha-((ethylamino)methyl)-m-hydroxy-, (+-)

113. .alpha.-[(ethylamino)methyl]-3-hydroxybenzenemethanol Hydrochloride

114. Benzenemethanol, .alpha-[(ethylamino)methyl]-3-hydroxy-, Hydrochloride

2.4 Create Date

2005-03-25

3 Chemical and Physical Properties

Molecular Formula	C₁₀H₁₅NO₂
Molecular Weight	181.23 g/mol
XLogP3	0.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	181.110278721 g/mol
Monoisotopic Mass	181.110278721 g/mol
Topological Polar Surface Area	52.5 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	141
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

Vasoconstrictor Agents

Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)

Adrenergic alpha-Agonists

Drugs that selectively bind to and activate alpha adrenergic receptors. (See all compounds classified as Adrenergic alpha-Agonists.)

Adrenergic beta-1 Receptor Agonists

Compounds that bind to and activate ADRENERGIC BETA-1 RECEPTORS. (See all compounds classified as Adrenergic beta-1 Receptor Agonists.)

Cardiotonic Agents

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)

4.2 ATC Code

C01CA01

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

C - Cardiovascular system

C01 - Cardiac therapy

C01C - Cardiac stimulants excl. cardiac glycosides

C01CA - Adrenergic and dopaminergic agents

C01CA01 - Etilefrine

ABOUT THIS PAGE

Ethyl Noradrianol Manufacturers

A Ethyl Noradrianol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ethyl Noradrianol, including repackagers and relabelers. The FDA regulates Ethyl Noradrianol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ethyl Noradrianol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ethyl Noradrianol Suppliers

A Ethyl Noradrianol supplier is an individual or a company that provides Ethyl Noradrianol active pharmaceutical ingredient (API) or Ethyl Noradrianol finished formulations upon request. The Ethyl Noradrianol suppliers may include Ethyl Noradrianol API manufacturers, exporters, distributors and traders.

Ethyl Noradrianol GMP

Ethyl Noradrianol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ethyl Noradrianol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ethyl Noradrianol GMP manufacturer or Ethyl Noradrianol GMP API supplier for your needs.

Ethyl Noradrianol CoA

A Ethyl Noradrianol CoA (Certificate of Analysis) is a formal document that attests to Ethyl Noradrianol's compliance with Ethyl Noradrianol specifications and serves as a tool for batch-level quality control.

Ethyl Noradrianol CoA mostly includes findings from lab analyses of a specific batch. For each Ethyl Noradrianol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ethyl Noradrianol may be tested according to a variety of international standards, such as European Pharmacopoeia (Ethyl Noradrianol EP), Ethyl Noradrianol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ethyl Noradrianol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.