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Chemistry

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Also known as: 5700-49-2, Jodethamine, Ethane-1,2-diamine dihydroiodide, Ethanediamine dihydroiodide, Hydrodine, Eddi
Molecular Formula
C2H10I2N2
Molecular Weight
315.92  g/mol
InChI Key
IWNWLPUNKAYUAW-UHFFFAOYSA-N
FDA UNII
721M52NQ5L

Ethylene Diamine Dihydro Iodide
1 2D Structure

Ethylene Diamine Dihydro Iodide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
ethane-1,2-diamine;dihydroiodide
2.1.2 InChI
InChI=1S/C2H8N2.2HI/c3-1-2-4;;/h1-4H2;2*1H
2.1.3 InChI Key
IWNWLPUNKAYUAW-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C(CN)N.I.I
2.2 Other Identifiers
2.2.1 UNII
721M52NQ5L
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1,2-diaminoethane

2. 1,2-ethanediamine

3. Edamine

4. Ethane-1,2-diamine

5. Ethyl Diamine

6. Ethylenediamine

7. Ethylenediamine (1:1) Sulfate

8. Ethylenediamine (1:1) Sulfite

9. Ethylenediamine Conjugate Acid

10. Ethylenediamine Dihydrobromide

11. Ethylenediamine Dihydrochloride

12. Ethylenediamine Dihydrogen Iodide

13. Ethylenediamine Dinitrate

14. Ethylenediamine Hydrochloride

15. Ethylenediamine Monohydrochloride

16. Ethylenediamine Phosphate

17. Ethylenediamine Sulfate

18. Ethylenediamine, 3h-labeled Cpd

2.3.2 Depositor-Supplied Synonyms

1. 5700-49-2

2. Jodethamine

3. Ethane-1,2-diamine Dihydroiodide

4. Ethanediamine Dihydroiodide

5. Hydrodine

6. Eddi

7. Ethylenediamine Dihydriodide

8. Orgadine

9. Ethylenediammonium Diiodide

10. Ethane-1,2-diamine;dihydroiodide

11. Ethylendiamine Dihydroiodide

12. 1,2-ethanediamine Dihydriodide

13. 1,2-ethanediamine Dihydroiodide

14. Chebi:81719

15. 721m52nq5l

16. Ethane-1,2-diammonium Iodide

17. Hiamine

18. Iomide

19. Hydriodide-boot

20. Iod-ethamine

21. Hy-odide

22. Hi-boot

23. Hydriodide-o-dide

24. Hi-o-dide

25. 1,2-ethanediamine, Dihydriodide

26. Unii-721m52nq5l

27. Hsdb 440

28. Ethane-1,2-diamine,dihydroiodide

29. Einecs 227-186-8

30. Hoffman Bonded E-d-d Iodine Compound

31. Whitmoyer Ethylene Diamine Dihydriodide

32. Dsstox_cid_24570

33. Dsstox_rid_80319

34. Dsstox_gsid_44570

35. Schembl1007637

36. Chembl3182879

37. Dtxsid5044570

38. 1,2-diaminoethane, Dihydroiodide

39. Tox21_302266

40. Mfcd00035535

41. Akos024334047

42. 1,2-ethanediamine, Hydriodide (1:2)

43. Ethane-1,2-diammonium Iodide, >=98%

44. Ncgc00255744-01

45. As-60979

46. Cas-5700-49-2

47. Db-052998

48. Ethylenediamine Dihydroiodide [hsdb]

49. E1222

50. Ft-0635813

51. C18382

52. T72638

53. 700e492

54. Q3027890

55. W-105492

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 315.92 g/mol
Molecular Formula C2H10I2N2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass315.89334 g/mol
Monoisotopic Mass315.89334 g/mol
Topological Polar Surface Area52 Ų
Heavy Atom Count6
Formal Charge0
Complexity6
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Therapeutic Uses

VET: ...ETHYLENEDIAMINE DIHYDROIODIDE (EDDI), IS FED TO CATTLE TO PREVENT OR TREAT VARIOUS AILMENTS SUCH AS FOOT ROT, MILD RESP CONDITIONS, ACTINOMYCOSIS, MASTITIS, OTHER CHRONIC INFECTIONS, & IODINE DEFICIENCY.

Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1284


VET: EXPECTORANT & ANTIINFLAMMATORY AGENT

Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1284


(VET): FEED ADDITIVE

Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 208


4.2 Drug Warning

VET: .../EDDI INTAKE/ SHOULD BE CURTAILED PRIOR TO CALVING, SHIPPING, VACCINATION, OR OTHER STRESSFUL SITUATIONS BECAUSE STRESS IS MAJOR FACTOR IN DEVELOPMENT OF EDDI-RELATED INFECTIONS.

Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1284


MORE RESEARCH IS NEEDED TO CHARACTERIZE DISEASE-ENHANCING ACTIONS OF EDDI REPORTED BY PRACTITIONERS & CATTLEMEN.

Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 01284


5 Pharmacology and Biochemistry
5.1 Absorption, Distribution and Excretion

IN CATTLE NORMAL TOTAL SERUM IODINE CONCN RANGES FROM 5.6 TO 14 UG/100 ML... IN SHEEP NORMAL TOTAL SERUM IODINE CONCN IS ABOUT 2.3-4.6 UG/100 ML... IN CASES OF EDDI-INDUCED IODISM &...INFECTION...TOTAL SERUM IODINE CONCN.../REPORTED/ 10-100 OR MORE TIMES NORMAL.

Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1285


IODIDES ARE READILY EXCRETED IN MILK /OF CATTLE/. ... IODIDES...ALSO SECRETED BY GLANDULAR CELLS IN RESP TRACT... SALIVARY & LACRIMAL GLANDS ALSO SECRETE IODIDES.

Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1284


5.2 Mechanism of Action

...REFLECTIONS OF PROSECRETORY ACTIONS OF IODIDE...SUSCEPTIBILITY OR PREDISPOSITION...TO MICROBIAL INFECTIONS /& FEVER/...ATTRIBUTED TO POSSIBLE ANTIINFLAMMATORY ACTION...ABILITY OF IODINE TO UNCOUPLE OXIDATIVE PHOSPHORYLATION.

Jones, L.M., et al. Veterinary Pharmacology & Therapeutics. 4th ed. Ames: Iowa State University Press, 1977., p. 1284


API Reference Price

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17-Dec-2021
18-Oct-2024
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Ethylene Diamine Dihydro Iodide Manufacturers

A Ethylene Diamine Dihydro Iodide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ethylene Diamine Dihydro Iodide, including repackagers and relabelers. The FDA regulates Ethylene Diamine Dihydro Iodide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ethylene Diamine Dihydro Iodide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ethylene Diamine Dihydro Iodide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ethylene Diamine Dihydro Iodide Suppliers

A Ethylene Diamine Dihydro Iodide supplier is an individual or a company that provides Ethylene Diamine Dihydro Iodide active pharmaceutical ingredient (API) or Ethylene Diamine Dihydro Iodide finished formulations upon request. The Ethylene Diamine Dihydro Iodide suppliers may include Ethylene Diamine Dihydro Iodide API manufacturers, exporters, distributors and traders.

click here to find a list of Ethylene Diamine Dihydro Iodide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ethylene Diamine Dihydro Iodide GMP

Ethylene Diamine Dihydro Iodide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ethylene Diamine Dihydro Iodide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ethylene Diamine Dihydro Iodide GMP manufacturer or Ethylene Diamine Dihydro Iodide GMP API supplier for your needs.

Ethylene Diamine Dihydro Iodide CoA

A Ethylene Diamine Dihydro Iodide CoA (Certificate of Analysis) is a formal document that attests to Ethylene Diamine Dihydro Iodide's compliance with Ethylene Diamine Dihydro Iodide specifications and serves as a tool for batch-level quality control.

Ethylene Diamine Dihydro Iodide CoA mostly includes findings from lab analyses of a specific batch. For each Ethylene Diamine Dihydro Iodide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ethylene Diamine Dihydro Iodide may be tested according to a variety of international standards, such as European Pharmacopoeia (Ethylene Diamine Dihydro Iodide EP), Ethylene Diamine Dihydro Iodide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ethylene Diamine Dihydro Iodide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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