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Chemistry

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Also known as: 36637-19-1, Duranest hydrochloride, Duranest, Etidocaine hcl, Etidocaine hydrochloride, (+)-, Etidocaine hydrochloride, (-)-
Molecular Formula
C17H29ClN2O
Molecular Weight
312.9  g/mol
InChI Key
LMWQQUMMGGIGJQ-UHFFFAOYSA-N
FDA UNII
G6N3B3U8E6

Etidocaine Hydrochloride
A local anesthetic with rapid onset and long action, similar to BUPIVACAINE.
1 2D Structure

Etidocaine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-(2,6-dimethylphenyl)-2-[ethyl(propyl)amino]butanamide;hydrochloride
2.1.2 InChI
InChI=1S/C17H28N2O.ClH/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5;/h9-11,15H,6-8,12H2,1-5H3,(H,18,20);1H
2.1.3 InChI Key
LMWQQUMMGGIGJQ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCCN(CC)C(CC)C(=O)NC1=C(C=CC=C1C)C.Cl
2.2 Other Identifiers
2.2.1 UNII
G6N3B3U8E6
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(ethylpropylamino)-2',6'-butyroxylidide

2. Duranest

3. Etidocaine

4. W 19053

5. W-19053

6. W19053

2.3.2 Depositor-Supplied Synonyms

1. 36637-19-1

2. Duranest Hydrochloride

3. Duranest

4. Etidocaine Hcl

5. Etidocaine Hydrochloride, (+)-

6. Etidocaine Hydrochloride, (-)-

7. Etidocaine (hydrochloride)

8. 38188-13-5

9. 60yd32ql30

10. Ygd0y35434

11. Duranest; Duranest Hydrochloride; W 19053

12. W-19053

13. N-(2,6-dimethylphenyl)-2-[ethyl(propyl)amino]butanamide;hydrochloride

14. (+/-)-n-(2,6-dimethylphenyl)-2-(ethylpropylamino)butyramide Monohydrochloride

15. Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, Monohydrochloride, (+)-

16. Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, Monohydrochloride, (-)-

17. 38188-14-6

18. G6n3b3u8e6

19. Unii-60yd32ql30

20. Unii-ygd0y35434

21. Duranest (tn)

22. Schembl419100

23. Chebi:4905

24. Chembl1200597

25. Hy-b2080a

26. Dtxsid70957895

27. Etidocaine Hydrochloride [mi]

28. Etidocaine Hydrochloride [mart.]

29. Etidocaine Hydrochloride [vandf]

30. Etidocaine Hydrochloride [who-dd]

31. Cs-0031033

32. Ft-0696974

33. Etidocaine Hydrochloride [orange Book]

34. D00737

35. Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, Hydrochloride

36. Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, Hydrochloride (1:1)

37. Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, Monohydrochloride

38. N-(2,6-dimethylphenyl)-2-[ethyl(propyl)amino]butanimidic Acid--hydrogen Chloride (1/1)

39. Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, (+/-)-, Monohydrochloride

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 312.9 g/mol
Molecular Formula C17H29ClN2O
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count7
Exact Mass312.1968412 g/mol
Monoisotopic Mass312.1968412 g/mol
Topological Polar Surface Area32.3 Ų
Heavy Atom Count21
Formal Charge0
Complexity283
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anesthetics, Local

Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)


ABOUT THIS PAGE

Etidocaine Hydrochloride Manufacturers

A Etidocaine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Etidocaine Hydrochloride, including repackagers and relabelers. The FDA regulates Etidocaine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Etidocaine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Etidocaine Hydrochloride Suppliers

A Etidocaine Hydrochloride supplier is an individual or a company that provides Etidocaine Hydrochloride active pharmaceutical ingredient (API) or Etidocaine Hydrochloride finished formulations upon request. The Etidocaine Hydrochloride suppliers may include Etidocaine Hydrochloride API manufacturers, exporters, distributors and traders.

Etidocaine Hydrochloride GMP

Etidocaine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Etidocaine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Etidocaine Hydrochloride GMP manufacturer or Etidocaine Hydrochloride GMP API supplier for your needs.

Etidocaine Hydrochloride CoA

A Etidocaine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Etidocaine Hydrochloride's compliance with Etidocaine Hydrochloride specifications and serves as a tool for batch-level quality control.

Etidocaine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Etidocaine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Etidocaine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Etidocaine Hydrochloride EP), Etidocaine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Etidocaine Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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