menu
    • menu

    Find Etravirine manufacturers, exporters & distributors on PharmaCompass

    Suanfarma, at the Core of a Better Life.

    Virtual Booth

    Contact Supplier

    Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

    Virtual Booth

    Contact Supplier

    Egis is a Hungarian generic pharma company with 110 years history. Our activities incorporate all areas of the pharma value chain.

    Virtual Booth

    Contact Supplier

    Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

    Virtual Booth

    Contact Supplier

    Transo-Pharm GmbH works globally to supply Active Pharmaceutical Ingredients adhering to the highest quality & GMP standards.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2025-01-20

    Virtual Booth

    Contact Supplier

    ACTIVE PHARMA INGREDIENTS

    INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    DRUG PRODUCT COMPOSITIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    GLOBAL SALES INFORMATION

    MARKET PLACE

    PATENTS & EXCLUSIVITIES

    PharmaCompass

    Synopsis

    Product SearchProduct Search

    Synopsis

    ACTIVE PHARMA INGREDIENTS

    10

    API Suppliers

    API Suppliers

    6

    USDMF

    US DMFs Filed

    0

    CEP/COS

    CEP/COS Certifications

    0

    JDMF

    JDMFs Filed

    3

    EU WC

    EU WC

    1

    KDMF

    KDMF

    6

    NDC API

    NDC API

    0

    VMF

    NDC API

    6

    Listed Suppliers

    Other Suppliers

    API REF. PRICE (USD/KG)

    $
    $ 1,321

    MARKET PLACE

    1

    API

    0

    FDF

    4INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    24

    FDF Dossiers

    FDF Dossiers

    8

    FDA Orange Book

    FDA (Orange Book)

    7

    Europe

    Europe

    2

    Canada

    Canada

    1

    Australia

    Australia

    2

    South Africa

    South Africa

    4

    Listed Dossiers

    Listed Dossiers

    0 DRUGS IN DEVELOPMENT

    FDF DossiersDRUG PRODUCT COMPOSITIONS

    REF. STANDARDS OR IMPURITIES

    0

    EDQM

    0

    USP

    0

    JP

    0

    Others

    PATENTS & EXCLUSIVITIES

    0

    US Patents

    0

    US Exclusivities

    9

    Health Canada Patents

    DIGITAL CONTENT

    0

    Data Compilation #PharmaFlow

    0

    Stock Recap #PipelineProspector

    0

    Weekly News Recap #Phispers

    3

    News #PharmaBuzz

    GLOBAL SALES INFORMATION

    US Medicaid

    41,166,810

    Annual Reports

    NA

    Finished Drug Prices

    Listed Dossiers

    140 RELATED EXCIPIENT COMPANIES

    219EXCIPIENTS BY APPLICATIONS

    Chemistry

    Click the arrow to open the dropdown
    read-moreClick the button for full data set
    read-moreClick the button for full data set
    Also known as: 269055-15-4, Intelence, Tmc-125, Tmc125, Etravirine (tmc125), Tmc 125
    Molecular Formula
    C20H15BrN6O
    Molecular Weight
    435.3  g/mol
    InChI Key
    PYGWGZALEOIKDF-UHFFFAOYSA-N
    FDA UNII
    0C50HW4FO1
    Etravirine
    Etravirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in multiple conformations, both for native and mutant RT, thereby blocking the enzymatic activity of RT.
    Etravirine is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of etravirine is as a Non-Nucleoside Reverse Transcriptase Inhibitor, and Cytochrome P450 3A Inducer, and Cytochrome P450 2C9 Inhibitor, and Cytochrome P450 2C19 Inhibitor, and P-Glycoprotein Inhibitor.
    1 2D Structure

    Etravirine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile
    2.1.2 InChI
    InChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27)
    2.1.3 InChI Key
    PYGWGZALEOIKDF-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N
    2.2 Other Identifiers
    2.2.1 UNII
    0C50HW4FO1
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-benzonitrile

    2. Benzonitrile, 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-

    3. Intelence

    4. R165335

    5. Tmc 125

    6. Tmc-125

    7. Tmc125 Cpd

    2.3.2 Depositor-Supplied Synonyms

    1. 269055-15-4

    2. Intelence

    3. Tmc-125

    4. Tmc125

    5. Etravirine (tmc125)

    6. Tmc 125

    7. R165335

    8. R-165335

    9. 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile

    10. 4-({6-amino-5-bromo-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile

    11. 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile

    12. 0c50hw4fo1

    13. Chembl308954

    14. Chebi:63589

    15. Etravirine-d8

    16. 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-benzonitrile

    17. 4-(6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yloxy)-3,5-dimethylbenzonitrile

    18. Benzonitrile, 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-

    19. Benzonitrile, 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-

    20. Benzonitrile,4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-

    21. 65b

    22. Intelence(tm)

    23. Dapy Deriv

    24. 4-(6-amino-5-bromo-2-(4-cyanophenylamino)pyrimidin-4-yloxy)-3,5-dimethylbenzonitrile

    25. Intelence (tn)

    26. Diaminopyrimidine Deriv

    27. Tmc125 Cpd

    28. Unii-0c50hw4fo1

    29. Etravirine (jan/usan/inn)

    30. Etravirine [usan:inn:ban:jan]

    31. Etravirine [inn]

    32. Etravirine- Bio-x

    33. R 165335

    34. Etravine; Etravirine

    35. 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile

    36. R165335-tmc125

    37. 3m8p

    38. Etravirine [mi]

    39. Tmc-125/r-165335

    40. Etravirine [jan]

    41. Etravirine [usan]

    42. Etravirine [vandf]

    43. Etravirine [mart.]

    44. Etravirine [who-dd]

    45. Schembl52691

    46. Etravirine [ema Epar]

    47. Etravirine [orange Book]

    48. Dtxsid30181412

    49. Hms3651p20

    50. Zinc602632

    51. Bcp03562

    52. Ex-a4282

    53. Bdbm50103642

    54. S3080

    55. 4-({6-amino-5-bromo-2-[(4-

    56. Akos015896355

    57. Ac-8503

    58. Bcp9000006

    59. Ccg-269074

    60. Cs-0435

    61. Db06414

    62. He-0088

    63. Pb32778

    64. 4-[[4-amino-5-bromo-6-(4-cyano-2,6-dimethylphenyloxy)-2-pyrimidinyl]amino]benzonitrile

    65. 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethyl-benzonitrile

    66. Ncgc00345885-02

    67. Ncgc00345885-04

    68. Ba164437

    69. Hy-90005

    70. Bcp0726000193

    71. Db-067700

    72. Am20080899

    73. Cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-

    74. Ft-0658058

    75. Ft-0668442

    76. Ft-0668443

    77. Sw219570-1

    78. A26965

    79. D04112

    80. Ab01566873_01

    81. A818671

    82. Q414762

    83. Sr-01000944895

    84. J-513179

    85. Sr-01000944895-1

    86. 4-(6-amino-5-bromo-2-(4-cyanophenylamino)pyrimidin-4-ylamino)-3,5-dimethylbenzonitrile

    87. 4-[[4-amino 5-bromo-6-(4-cyano-2,6-dimethylphenyloxy)-2-pyrimidinyl]amino]benzonitrile

    88. 4-[[4-amino-5-bromo-6-(4-cyano-2,6-dimethylphenyloxy)-2-pyrimidinyl]-amino]benzonitrile

    89. 4-[[6-amino-5-bromo-2-(4-cyanoanilino)-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile

    90. 4-[6-amino-5-bromo-2-(4-cyano-phenylamino)-pyrimidin-4-yloxy]-3,5-dimethyl-benzonitrile

    91. 4-((6-amino-5-bromo-2-((4-cyanophenyl) Amino) Pyrimidin-4-yl) Oxy)-3, 5-dimethylbenzonitrile

    92. 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3, 5 Cdimethylbenzonitrile

    93. 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl -benzonitrile

    94. 4-[6-azanyl-5-bromanyl-2-[(4-cyanophenyl)amino]pyrimidin-4-yl]oxy-3,5-dimethyl-benzenecarbonitrile

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 435.3 g/mol
    Molecular Formula C20H15BrN6O
    XLogP34.5
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count7
    Rotatable Bond Count4
    Exact Mass434.04907 g/mol
    Monoisotopic Mass434.04907 g/mol
    Topological Polar Surface Area121 Ų
    Heavy Atom Count28
    Formal Charge0
    Complexity609
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameIntelence
    PubMed HealthEtravirine (By mouth)
    Drug ClassesAntiretroviral Agent
    Drug LabelINTELENCE (etravirine) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1).The chemical name for etravirine is 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzon...
    Active IngredientEtravirine
    Dosage FormTablet
    RouteOral
    Strength200mg; 25mg; 100mg
    Market StatusPrescription
    CompanyJanssen R And D

    2 of 2  
    Drug NameIntelence
    PubMed HealthEtravirine (By mouth)
    Drug ClassesAntiretroviral Agent
    Drug LabelINTELENCE (etravirine) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1).The chemical name for etravirine is 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzon...
    Active IngredientEtravirine
    Dosage FormTablet
    RouteOral
    Strength200mg; 25mg; 100mg
    Market StatusPrescription
    CompanyJanssen R And D

    4.2 Drug Indication

    Indicated as an adjunct therapy in the treatment of adult HIV-1 infections resistant to therapy with other NNRTIs and antiretroviral agents.

    FDA Label

    Intelence, in combination with a boosted protease inhibitor and other antiretroviral medicinal products, is indicated for the treatment of human-immunodeficiency-virus-type-1 (HIV-1) infection in antiretroviral-treatment-experienced adult patients and in antiretroviral-treatment-experienced paediatric patients from six years of age.

    This indication is based on week-48 analyses from two phase-III trials in highly pretreated patients where Intelence was investigated in combination with an optimised background regimen (OBR) which included darunavir/ritonavir. The indication in paediatric patients is based on 48-week analyses of a single-arm, phase-II trial in antiretroviral-treatment-experienced paediatric patients.

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Clinical trials have shown no prolongation of QT intervals on electrocardiograms after 8 days of dosing.

    5.2 MeSH Pharmacological Classification

    Reverse Transcriptase Inhibitors

    Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template. (See all compounds classified as Reverse Transcriptase Inhibitors.)

    5.3 FDA Pharmacological Classification
    5.3.1 Active Moiety
    ETRAVIRINE
    5.3.2 FDA UNII
    0C50HW4FO1
    5.3.3 Pharmacological Classes
    Cytochrome P450 2C9 Inhibitors [MoA]; Cytochrome P450 3A Inducers [MoA]; Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]; Non-Nucleoside Analog [EXT]; Non-Nucleoside Reverse Transcriptase Inhibitors [MoA]; P-Glycoprotein Inhibitors [MoA]; Cytochrome P450 2C19 Inhibitors [MoA]; Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]
    5.4 ATC Code

    J05AG04

    J05AG04

    S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

    J - Antiinfectives for systemic use

    J05 - Antivirals for systemic use

    J05A - Direct acting antivirals

    J05AG - Non-nucleoside reverse transcriptase inhibitors

    J05AG04 - Etravirine

    5.5 Absorption, Distribution and Excretion

    Absorption

    Maximum oral absorption is achieved in 2.5-4 hours. Absorption is unaffected by the concomitant use of oral ranitidine or omeprazole, which decrease gastric acidity. Administration under fasting conditions resulted in a near 50% decrease in systemic exposure (AUC) when compared to administration after a meal.

    Route of Elimination

    After a 800mg dose of radio-labelled etraverine, 93.7% was found to undergo fecal elimination, with 81.2% - 86.4% eliminated unchanged. 1.2% of the dose was renally eliminated, changed. Etravirine is dialyzable (hemodialysis).

    Volume of Distribution

    Distribution of etravirine into compartments other than plasma has not been evaluated in humans.

    Clearance

    Renal clearance of etravirine is negligible (<1.2%), thus no dose adjustments are required in patients with renal impairment. Clearance is shown to be reduced in patients with Hepatitis B and/or co-infection, however, the safety profile of etravirine does not call for dosage adjustments.

    5.6 Metabolism/Metabolites

    Metabolized (in vitro) by the liver CYP450 enzymes: CYP3A4, CYP2C9, CYP2C19. The major metabolites formed by a methyl hydroxylation of the dimethylbenzonitrile moiety retained less than 90% of etravirine's activity.

    5.7 Biological Half-Life

    Half life of 9.05-41 hours.

    5.8 Mechanism of Action

    Etravirine exerts its effects via direct inhibition of the reverse transcriptase enzyme of human immunodeficiency virus type 1 (HIV-1). It directly binds reverse transcriptase and consequently blocks DNA-dependent and RNA-dependent polymerase activity. Etravirine does not inhibit human DNA polymerase alpha, beta or gamma.

    API SUPPLIERS

    read-more
    read-more
    Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

    API Reference Price

    read-more
    read-more
    [{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1642530600,"product":"ETRAVIRINE STANDARD B.NO.EV0111021","address":"882\/1-871, NEAR KANKAVATI ,VILLAGE-","city":"AHMEDABAD, GUJARAT","supplier":"AMNEAL PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"JOHN F. KENNEDY APT\/","customer":"AMNEAL PHARMACEUTICALS","customerCountry":"UNITED STATES","quantity":"0.01","actualQuantity":"8","unit":"GMS","unitRateFc":"1.4","totalValueFC":"11.1","currency":"USD","unitRateINR":103.625,"date":"19-Jan-2022","totalValueINR":"829","totalValueInUsd":"11.1","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29420090","bill_no":"4000310","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad-ZIPL-SEZ","supplierAddress":"882\/1-871, NEAR KANKAVATI ,VILLAGE-, AHMEDABAD, GUJARAT","customerAddress":""},{"dataSource":"API Import","activeIngredients":"ETRAVIRINE","year":"2021","qtr":"Q1","strtotime":1615746600,"product":"(N.C.V) ETRAVIRINE 250MG\/G SPRAY DRIED POWDER (FOR TESTING PURPOSE ONLY)","address":"30 FORJETT STREETPOST BOX NO 9301","city":"MUMBAI, MAHARASHTRA.","supplier":"JOHNSON & JOHNSON","supplierCountry":"BELGIUM","foreign_port":"BRUSSELS","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"3.10","actualQuantity":"3095.14","unit":"GMS","unitRateFc":"3.8","totalValueFC":"14587.2","currency":"EUR","unitRateINR":"343.1","date":"15-Mar-2021","totalValueINR":"1061968.78","totalValueInUsd":"14587.2","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"3154389","productDescription":"API","marketType":"REGULATED MARKET","country":"BELGIUM","selfForZScoreResived":"Pharma Grade","supplierPort":"BRUSSELS","supplierAddress":"","customerAddress":"30 FORJETT STREETPOST BOX NO 9301"},{"dataSource":"API Import","activeIngredients":"ETRAVIRINE","year":"2021","qtr":"Q1","strtotime":1617042600,"product":"ETRAVIRINE (QTY: 2 X 0.55 GMS, PRICE: USD-42.39\/EACH)(FOC)","address":"106, FIRST FLOOR , ASHOKA BHOOPALCHAMBERS BEGUMPET, S.P. ROAD,","city":"HYDERABAD-A.P.","supplier":"THE U.S. PHARMACOPEIAL ","supplierCountry":"INDIA","foreign_port":"","customer":"UNITED STATES PHARMACOPEIA ","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0011","unit":"KGS","unitRateFc":"77072.7","totalValueFC":"87.1","currency":"USD","unitRateINR":"5763918.2","date":"30-Mar-2021","totalValueINR":"6340.31","totalValueInUsd":"87.1","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"3351632","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"","supplierAddress":"","customerAddress":"106, FIRST FLOOR , ASHOKA BHOOPALCHAMBERS BEGUMPET, S.P. ROAD,"},{"dataSource":"API Import","activeIngredients":"ETRAVIRINE","year":"2021","qtr":"Q2","strtotime":1620412200,"product":"(N.C.V) ETRAVIRINE 222MG API PER G SOD POSTDRIED (FOR TESTING PURPOSE ONLY)","address":"30 FORJETT STREETPOST BOX NO 9301","city":"MUMBAI, MAHARASHTRA.","supplier":"JOHNSON & JOHNSON","supplierCountry":"BELGIUM","foreign_port":"BRUSSELS","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"3.13","actualQuantity":"3127.86","unit":"GMS","unitRateFc":"2.5","totalValueFC":"9557.5","currency":"EUR","unitRateINR":"223.8","date":"08-May-2021","totalValueINR":"700077.34","totalValueInUsd":"9557.5","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"3867687","productDescription":"API","marketType":"REGULATED MARKET","country":"BELGIUM","selfForZScoreResived":"Pharma Grade","supplierPort":"BRUSSELS","supplierAddress":"","customerAddress":"30 FORJETT STREETPOST BOX NO 9301"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1652293800,"product":"(N.C.V) ETRAVIRINE SPRAY DRIED-POWDER 250MG\/G (FOR TESTING PURPOSE ONLY)","address":"L.B.S. MARG,,MULUND-WEST","city":"MUMBAI,MAHARASHTRA","supplier":"JOHNSON & JOHNSON","supplierCountry":"BELGIUM","foreign_port":"NA","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"3.78","actualQuantity":"3780","unit":"GMS","unitRateFc":"4","totalValueFC":"16319.9","currency":"EUR","unitRateINR":"333.7","date":"12-May-2022","totalValueINR":"1261292.07","totalValueInUsd":"16319.9","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"8649638","productDescription":"API","marketType":"REGULATED MARKET","country":"BELGIUM","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"L.B.S. MARG,,MULUND-WEST"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1652812200,"product":"(N.C.V) ETRAVIRINE (FOR TESTING PURPOSE ONLY)","address":"L.B.S. MARG,,MULUND-WEST","city":"MUMBAI,MAHARASHTRA","supplier":"JOHNSON & JOHNSON","supplierCountry":"BELGIUM","foreign_port":"NA","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.20","actualQuantity":"195.58","unit":"GMS","unitRateFc":"5","totalValueFC":"1043.2","currency":"EUR","unitRateINR":"412.3","date":"18-May-2022","totalValueINR":"80627.85","totalValueInUsd":"1043.2","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"8731653","productDescription":"API","marketType":"REGULATED MARKET","country":"BELGIUM","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"L.B.S. MARG,,MULUND-WEST"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1657218600,"product":"(N.C.V)ETRAVIRINE 222MG\/G SPRAY DRIED POWDER (FOR TESTING PURPOSE ONLY)","address":"L.B.S. MARG,,MULUND-WEST","city":"MUMBAI,MAHARASHTRA","supplier":"JOHNSON & JOHNSON","supplierCountry":"BELGIUM","foreign_port":"NA","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.49","actualQuantity":"485.87","unit":"GMS","unitRateFc":"2.5","totalValueFC":"1244.9","currency":"EUR","unitRateINR":"203.7","date":"08-Jul-2022","totalValueINR":"98987.47","totalValueInUsd":"1244.9","indian_port":"BOMBAY AIR","hs_no":"29335990","bill_no":"9468447","productDescription":"API","marketType":"REGULATED MARKET","country":"BELGIUM","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"L.B.S. MARG,,MULUND-WEST"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1674066600,"product":"ETRAVIRINE (QTY: 1 X 100 MG, VALUE: USD 620)(FOC)","address":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"USP","supplierCountry":"INDIA","foreign_port":"NA","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0001","unit":"KGS","unitRateFc":"6200000","totalValueFC":"662.6","currency":"USD","unitRateINR":"541725900","date":"19-Jan-2023","totalValueINR":"54172.59","totalValueInUsd":"662.6","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"4247139","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1676831400,"product":"(N.C.V) ETRAVIRINE 250MG\/G SPRAY DRIED POWDER (FOR TESTING PURPOSE ONLY)","address":"L.B.S. MARG,,MULUND-WEST","city":"MUMBAI,MAHARASHTRA","supplier":"JOHNSON & JOHNSON","supplierCountry":"BELGIUM","foreign_port":"NA","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"3.20","actualQuantity":"3200","unit":"GMS","unitRateFc":"3.8","totalValueFC":"13354.2","currency":"EUR","unitRateINR":"344.7","date":"20-Feb-2023","totalValueINR":"1102927.2","totalValueInUsd":"13354.2","indian_port":"BOMBAY AIR","hs_no":"29335990","bill_no":"4719034","productDescription":"API","marketType":"REGULATED MARKET","country":"BELGIUM","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"L.B.S. MARG,,MULUND-WEST"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1719513000,"product":"(N.C.V) ETRAVIRINE (TMC 125 SPRAY DRIED POWDER) 250MG\/G (PLASTIC BAG IN ALUBAG) (FOR TESTING PURPOSE ONLY)","address":"30 FORJETT STREET","city":"MUMBAI, MAHARASHTRA.","supplier":"JOHNSON & JOHNSON","supplierCountry":"BELGIUM","foreign_port":"BRUSSELS","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"2.34","actualQuantity":"2335","unit":"GMS","unitRateFc":"3.7","totalValueFC":"9425.8","currency":"EUR","unitRateINR":"337","date":"28-Jun-2024","totalValueINR":"786858.07","totalValueInUsd":"9425.8","indian_port":"Bombay Air","hs_no":"29335990","bill_no":"4233602","productDescription":"API","marketType":"REGULATED MARKET","country":"BELGIUM","selfForZScoreResived":"Pharma Grade","supplierPort":"BRUSSELS","supplierAddress":"TURNHOUTSEWEG 30 B-2340 Beerse, , BelgiumSDNF Belgium","customerAddress":"30 FORJETT STREET"}]
    15-Mar-2021
    28-Jun-2024
    KGS
    overview
    Loading...

    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

    Total Value (USD)

    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

    Upgrade, download data, analyse, strategize, subscribe with us contact

    DRUG PRODUCT COMPOSITIONS

    Do you need Business Intel? Ask us

    DOSAGE - TABLET;ORAL - 100MG

    USFDA APPLICATION NUMBER - 22187

    read-more

    DOSAGE - TABLET;ORAL - 200MG

    USFDA APPLICATION NUMBER - 22187

    read-more

    DOSAGE - TABLET;ORAL - 25MG

    USFDA APPLICATION NUMBER - 22187

    read-more

    Related Excipient Companies

    Upload your portfolio for free, ask us

    Excipients by Applications

    Click here to find the perfect excipient manufacturers by their capabilities

    Fillers, Diluents & Binders

    read-more
    read-more

    Coating Systems & Additives

    read-more
    read-more

    Direct Compression

    read-more
    read-more

    Controlled & Modified Release

    read-more
    read-more

    Disintegrants & Superdisintegrants

    read-more
    read-more

    Thickeners and Stabilizers

    read-more
    read-more

    Granulation

    read-more
    read-more

    Lubricants & Glidants

    read-more
    read-more

    Co-Processed Excipients

    read-more
    read-more

    Film Formers & Plasticizers

    read-more
    read-more

    Empty Capsules

    read-more
    read-more

    Vegetarian Capsules

    read-more
    read-more

    Taste Masking

    read-more
    read-more

    API Stability Enhancers

    read-more
    read-more

    Emulsifying Agents

    read-more
    read-more

    Chewable & Orodispersible Aids

    read-more
    read-more

    Rheology Modifiers

    read-more
    read-more

    Coloring Agents

    read-more
    read-more

    Parenteral

    read-more
    read-more

    Solubilizers

    read-more
    read-more

    Digital Content read-more

    Create Content with PharmaCompass, ask us

    NEWS #PharmaBuzz

    read-more
    read-more

    Global Sales Information

    Do you need Business Intel? Ask us

    Market Place

    Do you need sourcing support? Ask us

    Patents & EXCLUSIVITIES

    Check the patents & exclusivity for this product

    ABOUT THIS PAGE

    Etravirine Manufacturers

    A Etravirine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Etravirine, including repackagers and relabelers. The FDA regulates Etravirine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Etravirine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Etravirine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Etravirine Suppliers

    A Etravirine supplier is an individual or a company that provides Etravirine active pharmaceutical ingredient (API) or Etravirine finished formulations upon request. The Etravirine suppliers may include Etravirine API manufacturers, exporters, distributors and traders.

    click here to find a list of Etravirine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Etravirine USDMF

    A Etravirine DMF (Drug Master File) is a document detailing the whole manufacturing process of Etravirine active pharmaceutical ingredient (API) in detail. Different forms of Etravirine DMFs exist exist since differing nations have different regulations, such as Etravirine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Etravirine DMF submitted to regulatory agencies in the US is known as a USDMF. Etravirine USDMF includes data on Etravirine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Etravirine USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Etravirine suppliers with USDMF on PharmaCompass.

    Etravirine KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Etravirine Drug Master File in Korea (Etravirine KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Etravirine. The MFDS reviews the Etravirine KDMF as part of the drug registration process and uses the information provided in the Etravirine KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Etravirine KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Etravirine API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Etravirine suppliers with KDMF on PharmaCompass.

    Etravirine WC

    A Etravirine written confirmation (Etravirine WC) is an official document issued by a regulatory agency to a Etravirine manufacturer, verifying that the manufacturing facility of a Etravirine active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Etravirine APIs or Etravirine finished pharmaceutical products to another nation, regulatory agencies frequently require a Etravirine WC (written confirmation) as part of the regulatory process.

    click here to find a list of Etravirine suppliers with Written Confirmation (WC) on PharmaCompass.

    Etravirine NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Etravirine as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Etravirine API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Etravirine as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Etravirine and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Etravirine NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Etravirine suppliers with NDC on PharmaCompass.

    Etravirine GMP

    Etravirine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Etravirine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Etravirine GMP manufacturer or Etravirine GMP API supplier for your needs.

    Etravirine CoA

    A Etravirine CoA (Certificate of Analysis) is a formal document that attests to Etravirine's compliance with Etravirine specifications and serves as a tool for batch-level quality control.

    Etravirine CoA mostly includes findings from lab analyses of a specific batch. For each Etravirine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Etravirine may be tested according to a variety of international standards, such as European Pharmacopoeia (Etravirine EP), Etravirine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Etravirine USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
    Ask Us for Pharmaceutical Supplier and Partner
    Ask Us, Find A Supplier / Partner
    No Commissions, No Strings Attached, Get Connected for FREE

    What are you looking for?

    How can we help you?

    The request can't be empty

    Please read our Privacy Policy carefully

    You must agree to the privacy policy

    The name can't be empty
    The company can't be empty.
    The email can't be empty Please enter a valid email.
    The mobile can't be empty

    Market Place

    Market Place

    PharmaCompass

    Home

    Market Place

    Menu

    Post Enquiry

    Post Enquiry

    Market Place

    Market Place

    Search