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Chemistry

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Also known as: 1593673-23-4, Msp-2017, (-)-msp-2017, Ms)-msp-2017, S82a18y42p, Methyl (s)-3-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate
Molecular Formula
C27H36N2O4
Molecular Weight
452.6  g/mol
InChI Key
VAZNEHLGJGSQEL-MHZLTWQESA-N
FDA UNII
S82A18Y42P

Etripamil
Etripamil has been used in trials studying the treatment of Paroxysmal Supraventricular Tachycardia (PSVT).
1 2D Structure

Etripamil

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
methyl 3-[2-[[(4S)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl]-methylamino]ethyl]benzoate
2.1.2 InChI
InChI=1S/C27H36N2O4/c1-20(2)27(19-28,23-11-12-24(31-4)25(18-23)32-5)14-8-15-29(3)16-13-21-9-7-10-22(17-21)26(30)33-6/h7,9-12,17-18,20H,8,13-16H2,1-6H3/t27-/m0/s1
2.1.3 InChI Key
VAZNEHLGJGSQEL-MHZLTWQESA-N
2.1.4 Canonical SMILES
CC(C)C(CCCN(C)CCC1=CC(=CC=C1)C(=O)OC)(C#N)C2=CC(=C(C=C2)OC)OC
2.1.5 Isomeric SMILES
CC(C)[C@](CCCN(C)CCC1=CC(=CC=C1)C(=O)OC)(C#N)C2=CC(=C(C=C2)OC)OC
2.2 Other Identifiers
2.2.1 UNII
S82A18Y42P
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Benzoic Acid, 3-(2-(((4s)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl)methylamino)ethyl)-, Methyl Ester

2. Methyl 3-(2-(((4s)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate

2.3.2 Depositor-Supplied Synonyms

1. 1593673-23-4

2. Msp-2017

3. (-)-msp-2017

4. Ms)-msp-2017

5. S82a18y42p

6. Methyl (s)-3-(2-((4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl)(methyl)amino)ethyl)benzoate

7. Benzoic Acid, 3-(2-(((4s)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl)methylamino)ethyl)- , Methyl Ester

8. Etripamil [usan:inn]

9. Unii-s82a18y42p

10. Etripamil [inn]

11. Etripamil (usan/inn)

12. Etripamil [usan]

13. Etripamil [who-dd]

14. Chembl3707312

15. Ex-a5306

16. Db12605

17. Hy-17611

18. Cs-0014689

19. D10932

20. Q27289030

21. Benzoic Acid, 3-(2-(((4s)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl)methylamino)ethyl)-, Methyl Ester

22. Methyl 3-[2-[[(4s)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl]-methylamino]ethyl]benzoate

2.4 Create Date
2015-07-27
3 Chemical and Physical Properties
Molecular Weight 452.6 g/mol
Molecular Formula C27H36N2O4
XLogP33.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count13
Exact Mass452.26750763 g/mol
Monoisotopic Mass452.26750763 g/mol
Topological Polar Surface Area71.8 Ų
Heavy Atom Count33
Formal Charge0
Complexity645
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Treatment of supraventricular arrhythmias


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Calcium Channel Blockers

A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)


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ABOUT THIS PAGE

Etripamil Manufacturers

A Etripamil manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Etripamil, including repackagers and relabelers. The FDA regulates Etripamil manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Etripamil API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Etripamil manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Etripamil Suppliers

A Etripamil supplier is an individual or a company that provides Etripamil active pharmaceutical ingredient (API) or Etripamil finished formulations upon request. The Etripamil suppliers may include Etripamil API manufacturers, exporters, distributors and traders.

click here to find a list of Etripamil suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Etripamil GMP

Etripamil Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Etripamil GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Etripamil GMP manufacturer or Etripamil GMP API supplier for your needs.

Etripamil CoA

A Etripamil CoA (Certificate of Analysis) is a formal document that attests to Etripamil's compliance with Etripamil specifications and serves as a tool for batch-level quality control.

Etripamil CoA mostly includes findings from lab analyses of a specific batch. For each Etripamil CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Etripamil may be tested according to a variety of international standards, such as European Pharmacopoeia (Etripamil EP), Etripamil JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Etripamil USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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