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Details:
ETX0462, a novel non-β-lactam PBP inhibitor, has potent antibacterial activity against a panel of geographically diverse Gram-negative bacterial clinical isolates.
Lead Product(s): ETX0462
Therapeutic Area: Infections and Infectious Diseases Product Name: ETX0462
Highest Development Status: PreclinicalProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 09, 2022
Details:
ETX0462 is novel, first-in-class, diazabicyclooctane with antimicrobial activity against multidrug-resistant Gram-negative and biothreat pathogens including, P. aeruginosa, K. pneumoniae, S. maltophilia, E. coli, B. anthracis, Y. pestis, F. tularensis and Burkholderia.
Lead Product(s): ETX0462
Therapeutic Area: Infections and Infectious Diseases Product Name: ETX0462
Highest Development Status: PreclinicalProduct Type: Small molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 15, 2021
Details:
Funding from the contract will support research towards developing molecules with expanded Gram-negative spectrum against antibiotic resistant bacterial pathogens including E. coli, Acinetobacter, Pseudomonas and Klebsiella.
Lead Product(s): ETX0462
Therapeutic Area: Infections and Infectious Diseases Product Name: ETX0462
Highest Development Status: PreclinicalProduct Type: Undisclosed
Partner/Sponsor/Collaborator: National Institutes of Health
Deal Size: $15.5 million Upfront Cash: $3.0 million
Deal Type: Funding July 06, 2020
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