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1. (1s,9s)-1-amino-9-ethyl-5-fluoro-2,3-dihydro-9-hydroxy-4-methyl-1h,12h-benzo(de)pyrano(3',4'-6,7)indolizino(1,2-b)quinoline-10,13(9h,15h)dione Methanesulfonate
2. Dx 8951
3. Dx 8951f
4. Dx-8951
5. Dx-8951a
6. Dx-8951f
7. Exatecan Mesilate Hydrate
8. Exatecan Mesylate
9. Exatecan Methanesulfonate Dihydrate
1. 171335-80-1
2. Exatecan [inn]
3. Dx-8951f
4. Oc71pp0f89
5. Dx-8951
6. (1s,9s)-1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10h,13h-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione
7. Dx 8951
8. Unii-oc71pp0f89
9. Exatecan-mesylate
10. (1s,9s)-1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10h,13h-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-10,13-dione
11. Exatecan [mi]
12. Exatecan [who-dd]
13. Schembl2512959
14. Chembl1614650
15. Dtxsid60169061
16. Chebi:135709
17. Ex-a2683
18. Zinc3800855
19. Nsc829066
20. Akos005146469
21. At33978
22. Bcp9000674
23. Db12185
24. Nsc-829066
25. 10h,13h-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1s,9s)-
26. 10h,13h-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1s-trans)-
27. Ac-32495
28. Bp-27996
29. Hy-13631
30. Db-064817
31. Dx8951;dx 8951;dx-8951
32. 335e801
33. J-521361
34. Q5419343
35. (10s,23s)-23-amino-10-ethyl-18-fluoro-10-hydroxy-19-methyl-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaene-5,9-dione
| Molecular Weight | 435.4 g/mol |
|---|---|
| Molecular Formula | C24H22FN3O4 |
| XLogP3 | 0.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 1 |
| Exact Mass | 435.15943435 g/mol |
| Monoisotopic Mass | 435.15943435 g/mol |
| Topological Polar Surface Area | 106 Ų |
| Heavy Atom Count | 32 |
| Formal Charge | 0 |
| Complexity | 950 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Topoisomerase I Inhibitors
Compounds that inhibit the activity of DNA TOPOISOMERASE I. (See all compounds classified as Topoisomerase I Inhibitors.)
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Drugs in Development
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CAS Number : 110351-94-5
End Use API : Exatecan
About The Company : Hangzhou Hairui Chemical Co., Ltd. is located in the Zhongheng Century Science and Technology Park in Hangzhou, Zhejiang. It is an excellent manufacturer of org...
CAS Number : 110351-94-5
End Use API : Exatecan
About The Company : Established in 2011 and situated in Hangzhou, Zhejiang, China, Hangzhou Longshine Bio-Tech CO., Ltd is dedicated to providing services for pharmaceutical and ch...
CAS Number : 110351-94-5
End Use API : Exatecan
About The Company : Hefei Hirisun Pharmatech Co., Ltd located in Hefei China, is a leading and developing Biotech enterprise, specialize in providing fine chemical, novel biochemic...
CAS Number : 110351-94-5
End Use API : Exatecan
About The Company : Gruechem, established in 2011, is dedicated to the custom synthesis, and custom-manufacturing of building blocks, core skeletons, and molecular frameworks, whic...
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ABOUT THIS PAGE
A Exatecan manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Exatecan, including repackagers and relabelers. The FDA regulates Exatecan manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Exatecan API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Exatecan manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Exatecan supplier is an individual or a company that provides Exatecan active pharmaceutical ingredient (API) or Exatecan finished formulations upon request. The Exatecan suppliers may include Exatecan API manufacturers, exporters, distributors and traders.
click here to find a list of Exatecan suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Exatecan DMF (Drug Master File) is a document detailing the whole manufacturing process of Exatecan active pharmaceutical ingredient (API) in detail. Different forms of Exatecan DMFs exist exist since differing nations have different regulations, such as Exatecan USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Exatecan DMF submitted to regulatory agencies in the US is known as a USDMF. Exatecan USDMF includes data on Exatecan's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Exatecan USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Exatecan suppliers with USDMF on PharmaCompass.
Exatecan Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Exatecan GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Exatecan GMP manufacturer or Exatecan GMP API supplier for your needs.
A Exatecan CoA (Certificate of Analysis) is a formal document that attests to Exatecan's compliance with Exatecan specifications and serves as a tool for batch-level quality control.
Exatecan CoA mostly includes findings from lab analyses of a specific batch. For each Exatecan CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Exatecan may be tested according to a variety of international standards, such as European Pharmacopoeia (Exatecan EP), Exatecan JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Exatecan USP).
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