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Chemistry

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Also known as: 41136-22-5, Falomesin, Celoslin, Alomen, Ceftezole sodium [jan], 3nhz4y117h
Molecular Formula
C13H11N8NaO4S3
Molecular Weight
462.5  g/mol
InChI Key
UGUMHWUOXWFPFH-JHQAJZDGSA-M
FDA UNII
3NHZ4Y117H

Falomesin
Ceftezole Sodium is the sodium salt form of ceftezole, a semi-synthetic first-generation cephalosporin with antibacterial activity.
1 2D Structure

Falomesin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(6R,7R)-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
2.1.2 InChI
InChI=1S/C13H12N8O4S3.Na/c22-7(1-20-4-14-18-19-20)16-8-10(23)21-9(12(24)25)6(2-26-11(8)21)3-27-13-17-15-5-28-13;/h4-5,8,11H,1-3H2,(H,16,22)(H,24,25);/q;+1/p-1/t8-,11-;/m1./s1
2.1.3 InChI Key
UGUMHWUOXWFPFH-JHQAJZDGSA-M
2.1.4 Canonical SMILES
C1C(=C(N2C(S1)C(C2=O)NC(=O)CN3C=NN=N3)C(=O)[O-])CSC4=NN=CS4.[Na+]
2.1.5 Isomeric SMILES
C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CN3C=NN=N3)C(=O)[O-])CSC4=NN=CS4.[Na+]
2.2 Other Identifiers
2.2.1 UNII
3NHZ4Y117H
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ceftezol

2. Ceftezol, Sodium Salt

3. Ceftezole

4. Celoslin

5. Demethylcefazolin

6. Falomesin

2.3.2 Depositor-Supplied Synonyms

1. 41136-22-5

2. Falomesin

3. Celoslin

4. Alomen

5. Ceftezole Sodium [jan]

6. 3nhz4y117h

7. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 8-oxo-7-((1h-tetrazol-1-ylacetyl)amino)-3-((1,3,4-thiadiazol-2-ylthio)methyl)-, Monosodium Salt, (6r-trans)-

8. Ceftezole Sodium (jan)

9. Dsstox_cid_28520

10. Dsstox_rid_82792

11. Dsstox_gsid_48594

12. Sodium (6r,7r)-3-(((1,3,4-thiadiazol-2-yl)thio)methyl)-7-(2-(1h-tetrazol-1-yl)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

13. Cas-41136-22-5

14. Ceftezole Sodium Salt

15. Ncgc00182064-02

16. Ncgc00183098-01

17. Unii-3nhz4y117h

18. Ceftezolesodium

19. Falomesin (tn)

20. Celoslin (tn)

21. Schembl1649887

22. Celoslin Sodium;falomesin Sodium

23. Dtxsid1048594

24. Chebi:31382

25. Ceftezole Sodium [mart.]

26. Ceftezole Sodium [who-dd]

27. Ceftezole Sodium Salt [mi]

28. Hy-n7096

29. Tox21_112923

30. Tox21_113140

31. Ccg-269369

32. As-83858

33. Cs-0019767

34. D01517

35. D81767

36. A899671

37. Q27257756

38. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 8-oxo-7-((2-(1h-tetrazol-1-yl)acetyl)amino)-3-((1,3,4-thiadiazol-2-ylthio)methyl)-, Sodium Salt (1:1), (6r,7r)-

39. 8-oxo-7-[(1h-tetrazol-1-ylacetyl)amino]-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Monosodium Salt

40. Sodium (6r,7r)-3-((1,3,4-thiadiazol-2-ylthio)methyl)-7-(2-(1h-tetrazol-1-yl)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

41. Sodium (7r)-7-(2-(1h-tetrazol-1-yl)acetamido)-3-(1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylate

42. Sodium,(6r,7r)-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

43. Sodium;(6r,7r)-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 462.5 g/mol
Molecular Formula C13H11N8NaO4S3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count12
Rotatable Bond Count7
Exact Mass461.99630866 g/mol
Monoisotopic Mass461.99630866 g/mol
Topological Polar Surface Area238 Ų
Heavy Atom Count29
Formal Charge0
Complexity716
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


ABOUT THIS PAGE

Falomesin Manufacturers

A Falomesin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Falomesin, including repackagers and relabelers. The FDA regulates Falomesin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Falomesin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Falomesin Suppliers

A Falomesin supplier is an individual or a company that provides Falomesin active pharmaceutical ingredient (API) or Falomesin finished formulations upon request. The Falomesin suppliers may include Falomesin API manufacturers, exporters, distributors and traders.

Falomesin GMP

Falomesin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Falomesin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Falomesin GMP manufacturer or Falomesin GMP API supplier for your needs.

Falomesin CoA

A Falomesin CoA (Certificate of Analysis) is a formal document that attests to Falomesin's compliance with Falomesin specifications and serves as a tool for batch-level quality control.

Falomesin CoA mostly includes findings from lab analyses of a specific batch. For each Falomesin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Falomesin may be tested according to a variety of international standards, such as European Pharmacopoeia (Falomesin EP), Falomesin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Falomesin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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