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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

6 API Suppliers, 6 Listed Suppliers, $ API Reference Price

6 API Suppliers
6 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

4 FDF Dossiers, 4 Listed Dossiers

4 FDF Dossiers
4 Listed Dossiers

MARKET PLACE

10 APIs, 1 FDF Dossiers

marketPlace
10 APIs
1 FDF Dossiers

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 843

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

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0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Fropenem, 106560-14-9, Faropenem sodium, Faropenem sodium hydrate, (5r,6s)-6-[(1r)-1-hydroxyethyl]-7-oxo-3-[(2r)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5r,6s)-6-[(1r)-1-hydroxyethyl]-7-oxo-3-[(2r)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Molecular Formula

C₁₂H₁₅NO₅S

Molecular Weight

285.32 g/mol

InChI Key

HGGAKXAHAYOLDJ-FHZUQPTBSA-N

FDA UNII

F52Y83BGH3

Faropenem is a penem with a tetrahydrofuran substituent at position C2, with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes. Compared with imipenem, faropenem has improved chemical stability and reduced central nervous system effects. In addition, faropenem is resistant to hydrolysis by many beta-lactamases.

1 2D Structure

Faropenem

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

2.1.2 InChI

InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1

2.1.3 InChI Key

HGGAKXAHAYOLDJ-FHZUQPTBSA-N

2.1.4 Canonical SMILES

CC(C1C2N(C1=O)C(=C(S2)C3CCCO3)C(=O)O)O

2.1.5 Isomeric SMILES

C[C@H]([C@@H]1[C@@H]2N(C1=O)C(=C(S2)[C@H]3CCCO3)C(=O)O)O

2.2 Other Identifiers

2.2.1 UNII

F52Y83BGH3

2.3 Synonyms

2.3.1 MeSH Synonyms

1. (5r,6s)-6-(r)-1-hydroxyethyl-7-oxo-3-(r)-2-tetrahydrofuryl-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate

2. Fropenem

2.3.2 Depositor-Supplied Synonyms

1. Fropenem

2. 106560-14-9

3. Faropenem Sodium

4. Faropenem Sodium Hydrate

5. (5r,6s)-6-[(1r)-1-hydroxyethyl]-7-oxo-3-[(2r)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid

6. (5r,6s)-6-[(1r)-1-hydroxyethyl]-7-oxo-3-[(2r)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid

7. Chebi:51257

8. F52y83bgh3

9. (+)-(5r,6s)-6-((1r)-1-hydroxyethyl)-7-oxo-3-((2r)-tetrahydro-2-furyl)-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic Acid

10. 122547-49-3

11. Ncgc00164546-02

12. 122547-49-3 (na)

13. Dsstox_cid_26430

14. Dsstox_rid_81608

15. Dsstox_gsid_46430

16. (5r,6s)-6-((r)-1-hydroxyethyl)-7-oxo-3-((r)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid

17. 6alpha-[(1r)-1-hydroxyethyl]-2-[(2r)-tetrahydrofuran-2-yl]-2,3-didehydropenam-3-carboxylic Acid

18. 6alpha-[(r)-1-hydroxyethyl]-2-[(r)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic Acid

19. Fropenem [inn]

20. (5r,6s)-6-(1-hydroxyethyl)-7-oxo-3-[(2r)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid

21. Cas-106560-14-9

22. Faropenem [usan:inn]

23. Unii-f52y83bgh3

24. Ncgc00164546-01

25. (5r,6s)-6-((1r)-1-hydroxyethyl)-7-oxo-3-((2r)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic Acid

26. Faropenem [inn]

27. Faropenem [mi]

28. Faropenem [who-dd]

29. Schembl239381

30. Chembl556262

31. Dtxsid0046430

32. Gtpl10808

33. Hy-a0035

34. Zinc3959242

35. Tox21_112175

36. Bdbm50483324

37. Compound 1 [pmid: 9216830]

38. Akos015895072

39. Tox21_112175_1

40. Db12190

41. Cs-0006739

42. H11961

43. 560f149

44. A801462

45. Sr-01000872591

46. J-001609

47. Q1397045

48. Sr-01000872591-1

49. 4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic Acid, 6-((1r)-1-hydroxyethyl)-7-oxo-3-((2r)-tetrahydro-2-furanyl)-,(5r,6s)

50. 4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid,6-[(1r)-1-hydroxyethyl]-7-oxo-3-[(2r)-tetrahydro-2-furanyl]-, (5r,6s)-

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₂H₁₅NO₅S
Molecular Weight	285.32 g/mol
XLogP3	0.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	285.06709375 g/mol
Monoisotopic Mass	285.06709375 g/mol
Topological Polar Surface Area	112 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	477
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 ATC Code

J - Antiinfectives for systemic use

J01 - Antibacterials for systemic use

J01D - Other beta-lactam antibacterials

J01DI - Other cephalosporins and penems

J01DI03 - Faropenem

API SUPPLIERS

01

Metrochem API Private Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM

Not Confirmed

Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

02

Hunan Warrant Chiral Pharmaceutica...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM

Not Confirmed

03

Vitalpharms

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM

Not Confirmed

04

Kopran

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM

Not Confirmed

05

Unipex

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM

Not Confirmed

06

Lunan Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

BIO Partnering at JPM

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

01

Metrochem API Private Limited

India

Pharma, Lab & Chemical Expo

Not Confirmed

Metrochem has been delivering customized volume & quality products to customers across the world, taking utmost care of their needs.

Contact Supplier

India

Virtual Booth

Digital Content

Faropenem

About the Company :

Established in 2004, Metrochem API is one of the fastest-growing APIs, pellets & intermediates manufacturers. It has 6 dedicated manufacturing facilities for its 3 core product ...

Established in 2004, Metrochem API is one of the fastest-growing APIs, pellets & intermediates manufacturers. It has 6 dedicated manufacturing facilities for its 3 core product groups and has been approved by ISO 9001-2015, USFDA, WHO GMP, Cofepris & Japanese authorities. Metrochem’s in-depth industry knowledge, & hi-tech & advanced infrastructure, helps it provide quality products to its customers. Note: None of the products will be supplied to the countries where this could conflict with existing patents. Further, any products under patent will be offered for R&D purposes only. However, the final responsibility lies with the buyer

Portfolio PDF

Product Web Link

Virtual Booth

China

Pharma, Lab & Chemical Expo

Not Confirmed

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API Reference Price

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E. MOSES","city":"MUMBAI ,MAHARASHTRA","supplier":"KOPRAN","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"DHAKA BANK LTD.","customerCountry":"BANGLADESH","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"925","totalValueFC":"45694.3","currency":"USD","unitRateINR":75860,"date":"30-Sep-2023","totalValueINR":"3793000","totalValueInUsd":"45694.3","indian_port":"Bombay Air","hs_no":"29419090","bill_no":"4327765","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"PARIJAT HOUSE,1076,DR. E. MOSES, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1703788200,"product":"PHARMACEUTICAL RAW MATERIAL FAROPENEM SODIUM HYDRATE JP (FAROPENEM SODIUM)","address":"PARIJAT HOUSE,1076,DR. E. 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HYDERABAD","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1628620200,"product":"(N.C.V)FAROPENEM SODIUM (FOR TESTING PURPOSE ONLY)","address":"1ST FLOOR PLOT NO 4 K K CHAMBERS, PURUSHOTTAMDAS THAKURDAS ROAD FORT","city":"MUMBAI,MAHARASHTRA","supplier":"LUCKTIN (HAINAN) BIOTECH CO., LTD.","supplierCountry":"CHINA","foreign_port":"HONG KONG","customer":"ZENVISION PHARMA LLP","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"5100","totalValueFC":"5164.1","currency":"USD","unitRateINR":"383010","date":"11-Aug-2021","totalValueINR":"383010","totalValueInUsd":"5164.1","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"5014019","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HONG KONG","supplierAddress":"","customerAddress":"1ST FLOOR PLOT NO 4 K K CHAMBERS, PURUSHOTTAMDAS THAKURDAS ROAD FORT"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1633285800,"product":"FAROPENEM SODIUM(NON-STERILE BULK)(34DRUM)","address":"304 AGGARWAL CITY SQUARE,MANGALAM","city":"DELHI,DELHI","supplier":"LONGCHEM INTERNATIONAL TRADING ","supplierCountry":"HONG KONG","foreign_port":"N\/A","customer":"SHAH TC GLOBAL ","customerCountry":"INDIA","quantity":"170.00","actualQuantity":"170","unit":"KGS","unitRateFc":"1080.2","totalValueFC":"182386.2","currency":"USD","unitRateINR":"80370.1","date":"04-Oct-2021","totalValueINR":"13662913","totalValueInUsd":"182386.2","indian_port":"ARSHIYA-SEZ\/PANVEL","hs_no":"29420090","bill_no":"1011533","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"HONG KONG","selfForZScoreResived":"Non-sterile","supplierPort":"N\/A","supplierAddress":"UNIT 2 OF LG 1 MIRROR TOWER 61 MODY ROAD TSIM SHA KOWLOON , , HONG KON G HONG KONG","customerAddress":"304 AGGARWAL CITY SQUARE,MANGALAM"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1726079400,"product":"FAROPENEM SODIUM (NON-STERILE BULK) JP LONGCHEM IUPAC NAME:4-THIA-1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID,6-[(1FAROPENEM SODIUM (NON-STERILE BULK) JP LONGCHEM IUPAC NAME:","address":"DARABSHAW HOUSE LEVEL 1 SHOORJI","city":"MUMBAI","supplier":"LUNAN PHARMACEUTICAL","supplierCountry":"CHINA","foreign_port":"NANNING","customer":"NHAVA SHEVA BUSINESS PARK PRIVATE LIMITED","customerCountry":"INDIA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"650","totalValueFC":"131704.5","currency":"USD","unitRateINR":"55185","date":"12-Sep-2024","totalValueINR":"11037000","totalValueInUsd":"131704.5","indian_port":"JNPT SEZ\/MUMBAI","hs_no":"29420090","bill_no":"5568418","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Non-sterile","supplierPort":"NANNING","supplierAddress":"NO.1, NORTH OUTER RING ROAD, FEIXIA N COUNTY, SHANDONG, CHINA Shandong, , CHINA CHINA","customerAddress":"DARABSHAW HOUSE LEVEL 1 SHOORJI"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1727721000,"product":"FAROPENEM SODIUM (NON-STERILE BULK) JP LONGCHEM IUPAC NAME:4-THIA-1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID,6-[(1FAROPENEM SODIUM (NON-STERILE BULK) JP LONGCHEM IUPAC NAME:","address":"305 AGGARWAL CITY SQUARE","city":"DELHI","supplier":"LONGCHEM INTERNATIONALTRADING COMPANY LIMITED","supplierCountry":"CHINA","foreign_port":"NANNING","customer":"SHAH TC DISTRIBUTION LLP","customerCountry":"INDIA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"650","totalValueFC":"130887.2","currency":"USD","unitRateINR":"54990","date":"01-Oct-2024","totalValueINR":"10998000","totalValueInUsd":"130887.2","indian_port":"JNPT SEZ\/MUMBAI","hs_no":"29420090","bill_no":"5903686","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Non-sterile","supplierPort":"NANNING","supplierAddress":"UNIT 2 OF LG 1, MIRROR TOWER, 61 MO DY ROAD, TSIM SHA TSUI, KOWLOON HON G KONG Kowloon, , HONG KONG HONG KONG","customerAddress":"305 AGGARWAL CITY SQUARE"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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FDF Dossiers

01

Associated Biotech

India

Pharma, Lab & Chemical Expo

Not Confirmed

02

Associated Biotech

India

Pharma, Lab & Chemical Expo

Not Confirmed

03

Health Biotech

India

Pharma, Lab & Chemical Expo

Not Confirmed

04

Smith & Kenner Pharmaceuticals

India

Pharma, Lab & Chemical Expo

Not Confirmed

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Listed Dossiers

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FDF DOSSIERS

Enquiry// Caspofungin, Palonosetron, Ticagrelor and Faropenem finished formulations needed in Vietnam [ENA00974]

A newly established company in Vietnam is looking for suppliers of following formulations: 1. Caspofungin powder infusion 2. Palonosetron soft capsules 3. Palonosetron injections 4. Ticagrelor tablets 5. Faropenem tablets

06 Jun 2018

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ABOUT THIS PAGE

Faropenem Manufacturers

A Faropenem manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Faropenem, including repackagers and relabelers. The FDA regulates Faropenem manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Faropenem API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Faropenem manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Faropenem Suppliers

A Faropenem supplier is an individual or a company that provides Faropenem active pharmaceutical ingredient (API) or Faropenem finished formulations upon request. The Faropenem suppliers may include Faropenem API manufacturers, exporters, distributors and traders.

click here to find a list of Faropenem suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Faropenem GMP

Faropenem Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Faropenem GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Faropenem GMP manufacturer or Faropenem GMP API supplier for your needs.

Faropenem CoA

A Faropenem CoA (Certificate of Analysis) is a formal document that attests to Faropenem's compliance with Faropenem specifications and serves as a tool for batch-level quality control.

Faropenem CoA mostly includes findings from lab analyses of a specific batch. For each Faropenem CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Faropenem may be tested according to a variety of international standards, such as European Pharmacopoeia (Faropenem EP), Faropenem JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Faropenem USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

Find Faropenem manufacturers, exporters & distributors on PharmaCompass

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ACTIVE PHARMA INGREDIENTS

6 API Suppliers

6 Listed Suppliers

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

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1 FDF Dossiers

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API REF. PRICE (USD/KG)

$ 843

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