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Chemistry

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Also known as: 10447-38-8, Phencarol, Diphenyl(quinuclidin-3-yl)methanol hydrochloride, 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol hydrochloride, Fenkarol, Fencarol
Molecular Formula
C20H24ClNO
Molecular Weight
329.9  g/mol
InChI Key
MVCBFPDJWSQMNY-UHFFFAOYSA-N
FDA UNII
6WSK4828LL

Fencarol
1 2D Structure

Fencarol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol;hydrochloride
2.1.2 InChI
InChI=1S/C20H23NO.ClH/c22-20(17-7-3-1-4-8-17,18-9-5-2-6-10-18)19-15-21-13-11-16(19)12-14-21;/h1-10,16,19,22H,11-15H2;1H
2.1.3 InChI Key
MVCBFPDJWSQMNY-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CN2CCC1C(C2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O.Cl
2.2 Other Identifiers
2.2.1 UNII
6WSK4828LL
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Fenatin

2. Fencarol

3. Phencarol

4. Quifenadine

5. Quifenadine Hydrobromide, (+-)-isomer

6. Quinuclidinyl-3-diphenylcarbinol

2.3.2 Depositor-Supplied Synonyms

1. 10447-38-8

2. Phencarol

3. Diphenyl(quinuclidin-3-yl)methanol Hydrochloride

4. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride

5. Fenkarol

6. Fencarol

7. 6wsk4828ll

8. 1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol;hydrochloride

9. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride;1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride

10. Alpha,alpha-diphenyl-3-quinuclidinemethanol Hydrochloride;alpha,alpha-diphenyl-3-quinuclidinemethanol Hydrochloride

11. Unii-6wsk4828ll

12. Alpha,alpha-diphenyl-3-quinuclidinemethanol, Hydrochloride

13. 3-quinuclidinemethanol, Alpha,alpha-diphenyl-, Hydrochloride

14. 1-azabicyclo(2.2.2)octane-3-methanol, Alpha,alpha-diphenyl-, Hydrochloride

15. Mls000765321

16. Chembl1510616

17. Schembl11613936

18. Dtxsid30908989

19. Akos005111025

20. Akos030507569

21. Am84319

22. Quifenadine Hydrochloride [who-dd]

23. Smr000289426

24. Ft-0682664

25. Diphenyl(quinuclidin-3-yl)methanolhydrochloride

26. (quinuclidin-3-yl)diphenylcarbinol Hydrochloride

27. A927551

28. Sr-01000323054

29. Sr-01000323054-1

30. (3-quinuclidinyl)diphenylcarbinolhydrochloride

31. Q27265638

32. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanolhydrochloride

33. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride (1:1)

34. 3-quinuclidinemethanol, .alpha.,.alpha.-diphenyl-, Hydrochloride

35. (1-azabicyclo[2.2.2]octan-3-yl)(diphenyl)methanol--hydrogen Chloride (1/1)

36. 1-azabicyclo(2.2.2)octane-3-methanol, .alpha.,.alpha.-diphenyl-, Hydrochloride

37. 1-azabicyclo(2.2.2)octane-3-methanol, .alpha.,.alpha.-diphenyl-, Hydrochloride (1:1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 329.9 g/mol
Molecular Formula C20H24ClNO
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass329.1546421 g/mol
Monoisotopic Mass329.1546421 g/mol
Topological Polar Surface Area23.5 Ų
Heavy Atom Count23
Formal Charge0
Complexity344
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Histamine Antagonists

Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only. (See all compounds classified as Histamine Antagonists.)


ABOUT THIS PAGE

Fencarol Manufacturers

A Fencarol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Fencarol, including repackagers and relabelers. The FDA regulates Fencarol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Fencarol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Fencarol Suppliers

A Fencarol supplier is an individual or a company that provides Fencarol active pharmaceutical ingredient (API) or Fencarol finished formulations upon request. The Fencarol suppliers may include Fencarol API manufacturers, exporters, distributors and traders.

Fencarol GMP

Fencarol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Fencarol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Fencarol GMP manufacturer or Fencarol GMP API supplier for your needs.

Fencarol CoA

A Fencarol CoA (Certificate of Analysis) is a formal document that attests to Fencarol's compliance with Fencarol specifications and serves as a tool for batch-level quality control.

Fencarol CoA mostly includes findings from lab analyses of a specific batch. For each Fencarol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Fencarol may be tested according to a variety of international standards, such as European Pharmacopoeia (Fencarol EP), Fencarol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Fencarol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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