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Chemistry

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Also known as: 10447-38-8, Phencarol, Diphenyl(quinuclidin-3-yl)methanol hydrochloride, 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol hydrochloride, Fenkarol, Fencarol
Molecular Formula
C20H24ClNO
Molecular Weight
329.9  g/mol
InChI Key
MVCBFPDJWSQMNY-UHFFFAOYSA-N
FDA UNII
6WSK4828LL

Fencarol
1 2D Structure

Fencarol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol;hydrochloride
2.1.2 InChI
InChI=1S/C20H23NO.ClH/c22-20(17-7-3-1-4-8-17,18-9-5-2-6-10-18)19-15-21-13-11-16(19)12-14-21;/h1-10,16,19,22H,11-15H2;1H
2.1.3 InChI Key
MVCBFPDJWSQMNY-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CN2CCC1C(C2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O.Cl
2.2 Other Identifiers
2.2.1 UNII
6WSK4828LL
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Fenatin

2. Fencarol

3. Phencarol

4. Quifenadine

5. Quifenadine Hydrobromide, (+-)-isomer

6. Quinuclidinyl-3-diphenylcarbinol

2.3.2 Depositor-Supplied Synonyms

1. 10447-38-8

2. Phencarol

3. Diphenyl(quinuclidin-3-yl)methanol Hydrochloride

4. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride

5. Fenkarol

6. Fencarol

7. 6wsk4828ll

8. 1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol;hydrochloride

9. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride;1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride

10. Alpha,alpha-diphenyl-3-quinuclidinemethanol Hydrochloride;alpha,alpha-diphenyl-3-quinuclidinemethanol Hydrochloride

11. Unii-6wsk4828ll

12. Alpha,alpha-diphenyl-3-quinuclidinemethanol, Hydrochloride

13. 3-quinuclidinemethanol, Alpha,alpha-diphenyl-, Hydrochloride

14. 1-azabicyclo(2.2.2)octane-3-methanol, Alpha,alpha-diphenyl-, Hydrochloride

15. Mls000765321

16. Chembl1510616

17. Schembl11613936

18. Dtxsid30908989

19. Akos005111025

20. Akos030507569

21. Am84319

22. Quifenadine Hydrochloride [who-dd]

23. Smr000289426

24. Ft-0682664

25. Diphenyl(quinuclidin-3-yl)methanolhydrochloride

26. (quinuclidin-3-yl)diphenylcarbinol Hydrochloride

27. A927551

28. Sr-01000323054

29. Sr-01000323054-1

30. (3-quinuclidinyl)diphenylcarbinolhydrochloride

31. Q27265638

32. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanolhydrochloride

33. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride (1:1)

34. 3-quinuclidinemethanol, .alpha.,.alpha.-diphenyl-, Hydrochloride

35. (1-azabicyclo[2.2.2]octan-3-yl)(diphenyl)methanol--hydrogen Chloride (1/1)

36. 1-azabicyclo(2.2.2)octane-3-methanol, .alpha.,.alpha.-diphenyl-, Hydrochloride

37. 1-azabicyclo(2.2.2)octane-3-methanol, .alpha.,.alpha.-diphenyl-, Hydrochloride (1:1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 329.9 g/mol
Molecular Formula C20H24ClNO
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass329.1546421 g/mol
Monoisotopic Mass329.1546421 g/mol
Topological Polar Surface Area23.5 Ų
Heavy Atom Count23
Formal Charge0
Complexity344
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Histamine Antagonists

Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only. (See all compounds classified as Histamine Antagonists.)


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