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    Chemistry

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    Also known as: 1944-12-3, Fenoterol hbr, Fenoterol (hydrobromide), Phenoterol hydrobromide, Fenoterol bromide, Chebi:31601
    Molecular Formula
    C17H22BrNO4
    Molecular Weight
    384.3  g/mol
    InChI Key
    SGZRQMALQBXAIQ-UHFFFAOYSA-N
    Fenoterol Hydrobromide
    A synthetic adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.
    1 2D Structure

    Fenoterol Hydrobromide

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    5-[1-hydroxy-2-[1-(4-hydroxyphenyl)propan-2-ylamino]ethyl]benzene-1,3-diol;hydrobromide
    2.1.2 InChI
    InChI=1S/C17H21NO4.BrH/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13;/h2-5,7-9,11,17-22H,6,10H2,1H3;1H
    2.1.3 InChI Key
    SGZRQMALQBXAIQ-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(CC1=CC=C(C=C1)O)NCC(C2=CC(=CC(=C2)O)O)O.Br
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. Berotec

    2. Berotek

    3. Fenoterol

    4. Fenoterol Hydrochloride

    5. Hydrochloride, Fenoterol

    6. P Hydroxyphenyl Orciprenaline

    7. P Hydroxyphenylorciprenaline

    8. P-hydroxyphenyl-orciprenaline

    9. P-hydroxyphenylorciprenaline

    10. Partusisten

    11. Phenoterol

    12. Th 1165a

    13. Th-1165a

    14. Th1165a

    2.2.2 Depositor-Supplied Synonyms

    1. 1944-12-3

    2. Fenoterol Hbr

    3. Fenoterol (hydrobromide)

    4. Phenoterol Hydrobromide

    5. Fenoterol Bromide

    6. Chebi:31601

    7. Partusisten

    8. Berotec

    9. 2-(3,5-dihydroxyphenyl)-2-hydroxy-2'-(4-hydroxyphenyl)-1'-methyldiethylamine Hydrobromide

    10. Dsstox_cid_25419

    11. Dsstox_rid_80867

    12. Dsstox_gsid_45419

    13. Fenoterol Bromide;th-1165a;phenoterol Hydrobromide

    14. Chembl537445

    15. 1,3-benzenediol,5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-,hydrobromide

    16. Cas-1944-12-3

    17. Th 1165a

    18. Nsc-757811

    19. Sr-01000075873

    20. Fenoterol Hydrobromide (jan)

    21. Fenoterol Hydrobromide [jan]

    22. Fenoterol-d6

    23. Prestwick_667

    24. Berotec (tn)

    25. Ncgc00016721-01

    26. Mls001056741

    27. Schembl121549

    28. Spectrum1501007

    29. Dtxsid5045419

    30. Hy-b0976a

    31. Regid_for_cid_5702161

    32. Hms1568j06

    33. Hms1921b11

    34. Pharmakon1600-01501007

    35. Bcp28959

    36. Einecs 217-742-8

    37. Tox21_110581

    38. Tox21_500544

    39. Ccg-38987

    40. Mfcd00079288

    41. Nsc757811

    42. S5768

    43. Akos015909691

    44. Tox21_110581_1

    45. Cs-5285

    46. Ks-5090

    47. Lp00544

    48. Ncgc00015430-06

    49. Ncgc00093932-01

    50. Ncgc00093932-02

    51. Ncgc00093932-03

    52. Ncgc00093932-04

    53. Ncgc00261229-01

    54. Smr000326705

    55. Eu-0100544

    56. Ft-0668501

    57. Ft-0668502

    58. Vu0243157-4

    59. D01428

    60. F 1016

    61. J-012593

    62. Sr-01000075873-1

    63. Sr-01000075873-6

    64. Q27114503

    65. Fenoterol Hydrobromide, British Pharmacopoeia (bp) Reference Standard

    66. Fenoterol Hydrobromide, European Pharmacopoeia (ep) Reference Standard

    67. 1,3-benzenediol, 5-(1-hydroxy-2-((2-(4-hydroxyphenyl)-1-methylethyl)amino)ethyl)-, Hbr

    68. 1-(3,5-dihydroxy-phenyl)-2-((1-(4-hydroxybenzyl)ethyl)amino)-ethanol Hydrobromide

    69. 5-(1-hydroxy-2-(1-(4-hydroxyphenyl)propan-2-ylamino)ethyl)benzene-1,3-diol Hydrobromide

    70. 5-(1-hydroxy-2-{[1-(4-hydroxyphenyl)propan-2-yl]amino}ethyl)benzene-1,3-diol (hbr)

    71. 5-(1-hydroxy-2-{[1-(4-hydroxyphenyl)propan-2-yl]amino}ethyl)benzene-1,3-diol Hydrobromide

    72. Fenoterol For Peak Identification, European Pharmacopoeia (ep) Reference Standard

    73. 5-[1-hydroxy-2-[[2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]benzene-1,3-diol Hydrobromide

    74. Benzyl Alcohol, 3,5-dihydroxy-alpha-(((p-hydroxy-alpha-methylphenethyl)amino)methyl)-, Hydrobromide

    2.3 Create Date
    2006-03-07
    3 Chemical and Physical Properties
    Molecular Weight 384.3 g/mol
    Molecular Formula C17H22BrNO4
    Hydrogen Bond Donor Count6
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count6
    Exact Mass383.07322 g/mol
    Monoisotopic Mass383.07322 g/mol
    Topological Polar Surface Area93 Ų
    Heavy Atom Count23
    Formal Charge0
    Complexity310
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count2
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Adrenergic beta-2 Receptor Agonists

    Compounds bind to and activate ADRENERGIC BETA-2 RECEPTORS. (See all compounds classified as Adrenergic beta-2 Receptor Agonists.)

    Tocolytic Agents

    Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete. (See all compounds classified as Tocolytic Agents.)

    Bronchodilator Agents

    Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)

    Sympathomimetics

    Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

    API Reference Price

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    02-Jan-2021
    07-Nov-2024
    KGS
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    Fenoterol Hydrobromide Manufacturers

    A Fenoterol Hydrobromide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Fenoterol Hydrobromide, including repackagers and relabelers. The FDA regulates Fenoterol Hydrobromide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Fenoterol Hydrobromide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Fenoterol Hydrobromide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Fenoterol Hydrobromide Suppliers

    A Fenoterol Hydrobromide supplier is an individual or a company that provides Fenoterol Hydrobromide active pharmaceutical ingredient (API) or Fenoterol Hydrobromide finished formulations upon request. The Fenoterol Hydrobromide suppliers may include Fenoterol Hydrobromide API manufacturers, exporters, distributors and traders.

    click here to find a list of Fenoterol Hydrobromide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Fenoterol Hydrobromide JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Fenoterol Hydrobromide Drug Master File in Japan (Fenoterol Hydrobromide JDMF) empowers Fenoterol Hydrobromide API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Fenoterol Hydrobromide JDMF during the approval evaluation for pharmaceutical products. At the time of Fenoterol Hydrobromide JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Fenoterol Hydrobromide suppliers with JDMF on PharmaCompass.

    Fenoterol Hydrobromide CEP

    A Fenoterol Hydrobromide CEP of the European Pharmacopoeia monograph is often referred to as a Fenoterol Hydrobromide Certificate of Suitability (COS). The purpose of a Fenoterol Hydrobromide CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Fenoterol Hydrobromide EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Fenoterol Hydrobromide to their clients by showing that a Fenoterol Hydrobromide CEP has been issued for it. The manufacturer submits a Fenoterol Hydrobromide CEP (COS) as part of the market authorization procedure, and it takes on the role of a Fenoterol Hydrobromide CEP holder for the record. Additionally, the data presented in the Fenoterol Hydrobromide CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Fenoterol Hydrobromide DMF.

    A Fenoterol Hydrobromide CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Fenoterol Hydrobromide CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Fenoterol Hydrobromide suppliers with CEP (COS) on PharmaCompass.

    Fenoterol Hydrobromide WC

    A Fenoterol Hydrobromide written confirmation (Fenoterol Hydrobromide WC) is an official document issued by a regulatory agency to a Fenoterol Hydrobromide manufacturer, verifying that the manufacturing facility of a Fenoterol Hydrobromide active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Fenoterol Hydrobromide APIs or Fenoterol Hydrobromide finished pharmaceutical products to another nation, regulatory agencies frequently require a Fenoterol Hydrobromide WC (written confirmation) as part of the regulatory process.

    click here to find a list of Fenoterol Hydrobromide suppliers with Written Confirmation (WC) on PharmaCompass.

    Fenoterol Hydrobromide NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Fenoterol Hydrobromide as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Fenoterol Hydrobromide API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Fenoterol Hydrobromide as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Fenoterol Hydrobromide and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Fenoterol Hydrobromide NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Fenoterol Hydrobromide suppliers with NDC on PharmaCompass.

    Fenoterol Hydrobromide GMP

    Fenoterol Hydrobromide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Fenoterol Hydrobromide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Fenoterol Hydrobromide GMP manufacturer or Fenoterol Hydrobromide GMP API supplier for your needs.

    Fenoterol Hydrobromide CoA

    A Fenoterol Hydrobromide CoA (Certificate of Analysis) is a formal document that attests to Fenoterol Hydrobromide's compliance with Fenoterol Hydrobromide specifications and serves as a tool for batch-level quality control.

    Fenoterol Hydrobromide CoA mostly includes findings from lab analyses of a specific batch. For each Fenoterol Hydrobromide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Fenoterol Hydrobromide may be tested according to a variety of international standards, such as European Pharmacopoeia (Fenoterol Hydrobromide EP), Fenoterol Hydrobromide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Fenoterol Hydrobromide USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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