menu
    • menu

    Find Fentanyl Hydrochloride manufacturers, exporters & distributors on PharmaCompass

    Aspen Fentanyl Hydrochloride

    Virtual Booth

    Contact Supplier

    Veranova Fentanyl Hydrochloride

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    Tofigh Daru Fentanyl Hydrochloride

    Virtual Booth

    Contact Supplier

    Bloomage is a one-stop source for CEP Sodium Hyaluronate and Hyaluronic Acid// FDA-inspected & GMP-certified.

    Virtual Booth

    Contact Supplier

    xyz-pharma-m-2024-10-07

    Virtual Booth

    Contact Supplier

    ACTIVE PHARMA INGREDIENTS

    FINISHED DOSAGE FORMULATIONS

    RELATED EXCIPIENT COMPANIES

    EXCIPIENTS BY APPLICATIONS

    DIGITAL CONTENT

    PATENTS & EXCLUSIVITIES

    REF. STANDARDS & IMPURITIES

    PharmaCompass

    Synopsis

    Related ProductsRelated Products

    Synopsis

    ACTIVE PHARMA INGREDIENTS

    4

    API Suppliers

    API Suppliers

    1

    USDMF

    US DMFs Filed

    0

    CEP/COS

    CEP/COS Certifications

    0

    JDMF

    JDMFs Filed

    0

    EU WC

    EU WC

    0

    KDMF

    KDMF

    2

    NDC API

    NDC API

    0

    VMF

    NDC API

    4

    Listed Suppliers

    Other Suppliers

    API REF. PRICE (USD/KG)

    $
    $ 288,705

    MARKET PLACE

    0

    API

    0

    FDF

    0INTERMEDIATES

    FINISHED DOSAGE FORMULATIONS

    3

    FDF Dossiers

    FDF Dossiers

    1

    FDA Orange Book

    FDA (Orange Book)

    2

    Europe

    Europe

    0

    Canada

    Canada

    0

    Australia

    Australia

    0

    South Africa

    South Africa

    0

    Listed Dossiers

    Listed Dossiers

    0 DRUGS IN DEVELOPMENT

    FDF Dossiers

    DRUG PRODUCT COMPOSITIONS

    REF. STANDARDS OR IMPURITIES

    0

    EDQM

    0

    USP

    0

    JP

    1

    Others

    PATENTS & EXCLUSIVITIES

    8

    US Patents

    0

    US Exclusivities

    0

    Health Canada Patents

    DIGITAL CONTENT

    1

    Data Compilation #PharmaFlow

    0

    Stock Recap #PipelineProspector

    0

    Weekly News Recap #Phispers

    5

    News #PharmaBuzz

    GLOBAL SALES INFORMATION

    US Medicaid

    NA

    Annual Reports

    NA

    Finished Drug Prices

    NA

    16 RELATED EXCIPIENT COMPANIES

    24EXCIPIENTS BY APPLICATIONS

    Chemistry

    Click the arrow to open the dropdown
    read-moreClick the button for full data set
    read-moreClick the button for full data set
    Also known as: Fentanyl hcl, 1443-54-5, 59h156xy46, Fentanyl hydrochloride (jan), Fentanyl hydrochloride [jan], N-phenyl-n-[1-(2-phenylethyl)piperidin-4-yl]propanamide;hydrochloride
    Molecular Formula
    C22H29ClN2O
    Molecular Weight
    372.9  g/mol
    InChI Key
    LHCBOXPPRUIAQT-UHFFFAOYSA-N
    FDA UNII
    59H156XY46
    Fentanyl Hydrochloride
    Fentanyl Hydrochloride is the hydrochloride salt form of fentanyl, a synthetic, lipophilic phenylpiperidine opioid agonist with analgesic and anesthetic properties. Fentanyl selectively binds to the mu-receptor in the central nervous system (CNS) thereby mimicking the effects of endogenous opiates. Stimulation of the mu-subtype opioid receptor stimulates the exchange of GTP for GDP on the G-protein complex and subsequently inhibits adenylate cyclase. This results in a decrease in intracellular cAMP and leads to a reduction in the release of neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline. The analgesic effect of fentanyl is likely due to its metabolite morphine, which induces opening of G-protein-coupled inwardly rectifying potassium (GIRK) channels and blocks the opening of N-type voltage-gated calcium channels, thereby resulting in hyperpolarization and reduced neuronal excitability.
    1 2D Structure

    Fentanyl Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide;hydrochloride
    2.1.2 InChI
    InChI=1S/C22H28N2O.ClH/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19;/h3-12,21H,2,13-18H2,1H3;1H
    2.1.3 InChI Key
    LHCBOXPPRUIAQT-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    59H156XY46
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. Fentanyl Hcl

    2. 1443-54-5

    3. 59h156xy46

    4. Fentanyl Hydrochloride (jan)

    5. Fentanyl Hydrochloride [jan]

    6. N-phenyl-n-[1-(2-phenylethyl)piperidin-4-yl]propanamide;hydrochloride

    7. Unii-59h156xy46

    8. Ionsys (tn)

    9. N-(1-phenethyl-4-piperidyl)propionanilide Hydrochloride

    10. Mls002320669

    11. Schembl242876

    12. Chembl1201159

    13. Dtxsid90162666

    14. Propionanilide, N-(1-phenethyl-4-piperidyl)-, Hydrochloride

    15. Fentanyl Hydrochloride [mart.]

    16. Fentanyl Hydrochloride [who-dd]

    17. Fentanyl Hydrochloride [ema Epar]

    18. Smr001338815

    19. Fentanyl Hydrochloride [orange Book]

    20. D10811

    21. Q27261701

    22. Propanamide, N-phenyl-n-(1-(2-phenylethyl)-4-piperidinyl)-, Monohydrochloride

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 372.9 g/mol
    Molecular Formula C22H29ClN2O
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count6
    Exact Mass372.1968412 g/mol
    Monoisotopic Mass372.1968412 g/mol
    Topological Polar Surface Area23.6 Ų
    Heavy Atom Count26
    Formal Charge0
    Complexity391
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Indication

    Ionsys is indicated for the management of acute moderate to severe post-operative pain in adult patients.

    Management of acute moderate to severe post-operative pain for use in a hospital setting only

    Treatment of acute pain

    5 Pharmacology and Biochemistry
    5.1 ATC Code

    N02AB03

    N02AB03

    Related Excipient Companies

    Upload your portfolio for free, ask us

    Excipients by Applications

    Click here to find the perfect excipient manufacturers by their capabilities

    Coating Systems & Additives

    read-more
    read-more

    Controlled & Modified Release

    read-more
    read-more

    Parenteral

    read-more
    read-more

    Disintegrants & Superdisintegrants

    read-more
    read-more

    API Stability Enhancers

    read-more
    read-more

    Topical

    read-more
    read-more

    Fillers, Diluents & Binders

    read-more
    read-more

    Taste Masking

    read-more
    read-more

    Digital Content read-more

    Create Content with PharmaCompass, ask us

    DATA COMPILATION #PharmaFlow

    read-more
    read-more

    NEWS #PharmaBuzz

    read-more
    read-more

    Patents & EXCLUSIVITIES

    Check the patents & exclusivity for this product

    REF. STANDARDS & IMPURITIES

    Upload your portfolio for free, ask us

    ABOUT THIS PAGE

    Ask Us for Pharmaceutical Supplier and Partner
    Ask Us, Find A Supplier / Partner
    No Commissions, No Strings Attached, Get Connected for FREE

    What are you looking for?

    How can we help you?

    The request can't be empty

    Please read our Privacy Policy carefully

    You must agree to the privacy policy

    The name can't be empty
    The company can't be empty.
    The email can't be empty Please enter a valid email.
    The mobile can't be empty

    Market Place

    Market Place

    PharmaCompass

    Home

    Market Place

    Menu

    Post Enquiry

    Post Enquiry

    Market Place

    Market Place

    Search